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1. 发明专利

JP2012157427A Input device for respiration training 审中-公开
标题翻译：用于呼吸训练的输入装置
公开(公告)号：JP2012157427A
公开(公告)日：2012-08-23
申请号：JP2011017736
申请日：2011-01-31
申请人： Toshiyuki Chiba , 敏行千葉
发明人： CHIBA TOSHIYUKI
IPC分类号： A63B23/18
摘要： PROBLEM TO BE SOLVED: To provide an input device for respiration training which is capable of providing an excellent training effect by enhancing user's eagerness.SOLUTION: The input device 1 for respiration training which is capable of controlling operation of an external device 40 by the user's respiration training, includes: a body part 10 having a breath passage 11 through which breath passes; a breath detection part 15 for detecting the strength of breathing into the breath passage 11; a count part for counting the number of times when a detected value of the breath detection part 15 exceeds a preset threshold; and a control part for externally outputting a control signal when a counted value of the count part reaches a preset reference value.
摘要翻译：要解决的问题：提供一种用于呼吸训练的输入装置，其能够通过增强用户的渴望来提供优异的训练效果。解决方案：能够通过用户的呼吸训练来控制外部设备40的操作的用于呼吸训练的输入设备1包括：身体部分10，其具有呼吸通过的呼吸通道11; 用于检测进入呼吸通道11的呼吸强度的呼吸检测部15; 计数部，用于对呼吸检测部15的检测值超过预设阈值的次数进行计数; 以及控制部，当计数部的计数值达到预先设定的基准值时，从外部输出控制信号。版权所有（C）2012，JPO＆INPIT

2. 发明授权

US5241064A Enzymatic process for preparing optically active 3-substituted azetidinones 失效
标题翻译：用于制备光学活性3-取代的AZETIDINONES的酶法
公开(公告)号：US5241064A
公开(公告)日：1993-08-31
申请号：US587037
申请日：1990-09-24
申请人： Masayoshi Murata , Toshiyuki Chiba , Fumiyuki Shirai , Kenichi Washizuka , Motohiro Hino
发明人： Masayoshi Murata , Toshiyuki Chiba , Fumiyuki Shirai , Kenichi Washizuka , Motohiro Hino
IPC分类号： C07B53/00 , C07D205/08 , C12P7/42 , C12P41/00
CPC分类号： C12R1/07 , C07D205/08 , C12P41/004 , C12P7/42 , Y02P20/55
摘要： Preparation of optically active 3-substituted azetidinones of the formula (I) ##STR1## in which R.sup.1 is a hydroxy-protective group wherein an allylic alcohol of the formula (II) ##STR2## is acylated, then subjected to asymmetric enzymatic hydrolysis yielding the R-allylic alcohol. The hydroxyl group is protected and then stereoselectively reacted with an amine which is subsequently cyclized to yield the desired 3-substituted azetidinone. Two new species of microorganisms have been isolated, Pimelobacter sp. No. 1254 and Bacillus megaterium No. 1253 which exhibit stereoselective esterase activity.

3. 发明授权

US5075437A 3,4-disubstituted-2-azetidinone derivatives and processes for preparation using tin enolates 失效
标题翻译： 3,4-取代的2-氮杂二酮衍生物和使用钛酸盐的制备方法
公开(公告)号：US5075437A
公开(公告)日：1991-12-24
申请号：US518993
申请日：1990-05-04
申请人： Takeshi Nakai , Fumiyuki Shirai , Toshiyuki Chiba , Hiroaki Ohtake
发明人： Takeshi Nakai , Fumiyuki Shirai , Toshiyuki Chiba , Hiroaki Ohtake
IPC分类号： C07D205/08 , C07D417/06 , C07F7/18
CPC分类号： C07D417/06 , C07D205/08 , C07F7/186 , Y02P20/55
摘要： The invention relates to the preparation of 3,4-disubstituted-2-azetidinone compounds of the formula: ##STR1## in which R.sup.1 is hydrogen or amido-protective group, R.sup.2 is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl, R.sup.3 is lower alkyl, and R.sup.4 is 1-(lower)alkyl-1-hydroxy(C.sub.2 -C.sub.6)alkyl, 1-(lower)alkyl-1-(protected hydroxy)-(C.sub.2 -C.sub.6)alkyl or 2-thioxothiazolidin-3-yl, useful as an intermediate for the production of antimicrobial agents by reacting a compound a compound of the formula: ##STR2## in which R.sup.5 is acyl, or salts thereof, with a compound of the formula:R.sup.3 --CH.sub.2 CO--R.sup.4or salts thereof, in the presence of an enolizating agent selected from the group consisting of stannous(lower)alkylsulfonate and stannous perhalo(lower)alkylsulfonate.

4. 发明授权

US4393059A Cephem compounds 失效
标题翻译：头孢烯化合物
公开(公告)号：US4393059A
公开(公告)日：1983-07-12
申请号：US302639
申请日：1981-09-15
申请人： Takao Takaya , Hisashi Takasugi , Kiyoshi Tsuji , Toshiyuki Chiba
发明人： Takao Takaya , Hisashi Takasugi , Kiyoshi Tsuji , Toshiyuki Chiba
IPC分类号： C07D277/20 , C07D285/06 , C07D501/59 , C07D501/20 , A61K31/545
CPC分类号： C07D277/20 , C07D285/06 , C07D501/20
摘要： The invention relates particularly to syn compounds of the formula: ##STR1## wherein R.sup.2 is hydrogen or an aliphatic hydrocarbon which may be substituted with halogen, carboxy or pharmaceutically acceptable esterified carboxy,R.sup.5 is carboxy or pharmaceutically acceptable esterified carboxy,R.sup.6 is amino or protected amino andR.sup.7 is lower alkanesulfonyl or arenesulfonyl and pharmaceutically acceptable salt thereof, processes for making them, pharmaceutical compositions containing them and their use in treating infectious diseases.
摘要翻译：本发明特别涉及下式的顺式化合物：其中R 2为氢或可被卤素，羧基或药学上可接受的酯化羧基取代的脂族烃基，R 5为羧基或药学上可接受的酯化羧基，R6为氨基或保护基氨基和R7是低级烷基磺酰基或芳烃磺酰基及其药学上可接受的盐，其制备方法，含有它们的药物组合物及其在治疗感染性疾病中的用途。

5. 发明授权

US07587683B2 Display method, portable terminal device, and display program 有权
标题翻译：显示方法，便携式终端设备和显示程序
公开(公告)号：US07587683B2
公开(公告)日：2009-09-08
申请号：US11318669
申请日：2005-12-27
申请人： Yuichi Ito , Toshiyuki Chiba , Tatsuya Hama , Yukako Morimoto
发明人： Yuichi Ito , Toshiyuki Chiba , Tatsuya Hama , Yukako Morimoto
IPC分类号： G06F3/048 , G06F3/00 , G06F15/177 , H04B1/00
CPC分类号： H04M1/72583 , G06F3/04817 , G06F3/0482 , H04M1/0214
摘要： A display method for displaying a plurality of icons in list form on a display device by a list-form displaying section and for enlarging and reducing an icon. When a first icon is selected while second icon previously selected is being enlarged, the second icon is enlarged to a predetermined size, and then after the enlargement, the enlarged second icon is reduced so as to have a size substantially equal to the size of each of icons which are not selected.
摘要翻译：一种用于通过列表形式显示部分在显示装置上以列表形式显示多个图标并用于放大和缩小图标的显示方法。当在先前选择的第二图标被放大时选择第一图标时，第二图标被放大到预定大小，然后在放大之后，放大的第二图标被减小，使得尺寸基本上等于每个图像的大小未选择的图标。

6. 发明申请

US20060116344A1 Remedy and preventive for diseases caused by NF-kB 审中-公开
标题翻译：补救和预防由NF-kB引起的疾病
公开(公告)号：US20060116344A1
公开(公告)日：2006-06-01
申请号：US11324230
申请日：2006-01-04
申请人： Ryuichi Morishita , Toshio Ogiwara , Toshiko Sugimoto , Kazuhiro Maeda , Ikuo Kawamura , Toshiyuki Chiba
发明人： Ryuichi Morishita , Toshio Ogiwara , Toshiko Sugimoto , Kazuhiro Maeda , Ikuo Kawamura , Toshiyuki Chiba
IPC分类号： A61K48/00 , C07H21/02
CPC分类号： A61K31/00 , A61K38/00 , A61K48/005 , C12N15/113 , C12N2310/13 , C12N2310/315
摘要： Administration of a decoy, i.e. a compound which specifically antagonizes the nucleic acid domain to which NF-κB is bound, is effective in the treatment and prevention of diseases caused by the transcriptional regulatory factor NF-κB, such as ischemic diseases, inflammatory diseases, autoimmune diseases, cancer metastasis and invasion, and cachexia.
摘要翻译：施用诱饵，即特异性拮抗NF-κB结合的核酸结构域的化合物在治疗和预防由转录调节因子NF-κB引起的疾病中是有效的，例如缺血性疾病，炎性疾病，自身免疫性疾病，癌症转移和侵袭以及恶病质。

7. 发明授权

US06262033B1 Remedy for diseases associated with NF-&kgr;B 失效
标题翻译：补救与NF-κB相关的疾病
公开(公告)号：US06262033B1
公开(公告)日：2001-07-17
申请号：US08945805
申请日：1998-01-06
申请人： Ryuichi Morishita , Toshio Ogiwara , Toshiko Sugimoto , Kazuhiro Maeda , Ikuo Kawamura , Toshiyuki Chiba
发明人： Ryuichi Morishita , Toshio Ogiwara , Toshiko Sugimoto , Kazuhiro Maeda , Ikuo Kawamura , Toshiyuki Chiba
IPC分类号： A61K4800
CPC分类号： A61K31/00 , A61K38/00 , A61K48/005 , C12N15/113 , C12N2310/13 , C12N2310/315
摘要： Administration of a decoy, i.e. a compound which specifically antagonizes the nucleic acid domain to which NF-&kgr;B is bound, is effective in the treatment and prevention of diseases caused by the transcriptional regulatory factor NF-&kgr;B, such as ischemic diseases, inflammatory diseases, autoimmune diseases, cancer metastasis and invasion, and cachexia.
摘要翻译：施用诱饵，即特异性拮抗NF-κB结合的核酸结构域的化合物在治疗和预防由转录调节因子NF-κB引起的疾病中是有效的，例如缺血性疾病，炎性疾病，自身免疫性疾病，癌症转移和侵袭以及恶病质。

8. 发明授权

US5529414A Paper feeding apparatus for printer 失效
标题翻译：打印机供纸装置
公开(公告)号：US5529414A
公开(公告)日：1996-06-25
申请号：US482527
申请日：1995-06-07
申请人： Keiji Katano , Toshiyuki Chiba
发明人： Keiji Katano , Toshiyuki Chiba
IPC分类号： B41J11/42 , B41J11/46 , B41J13/02
CPC分类号： B41J11/46 , B41J11/42
摘要： The present invention provides a paper feeding apparatus for a printer wherein a paper feed roller can be driven to rotate with a high degree of accuracy to achieve feeding of a paper sheet with a very high degree of accuracy. The paper feeding apparatus for a printer comprises a paper feed motor constituted from a stepping motor, a motor gear driven to rotate by the paper feed motor, a paper feed roller disposed for rotation for transporting a recording sheet to a printing position, the length of an outer periphery of the paper feed roller being set equal to N line feed distances, a paper feed gear for driving the paper feed roller to rotate, at least one transmission gear for transmitting rotating force of the motor gear to the paper feed gear, a detection element formed on the paper feed roller and indicating a reference position of the paper feed roller, a detector for detecting the detection element and generating a detection signal, and a control apparatus for receiving the detection signal from the detector and controlling driving of the paper feed motor so that, upon starting of paper feeding, the paper feed roller may be positioned normally at the reference position.
摘要翻译：本发明提供了一种用于打印机的送纸装置，其中可以高精度地驱动供纸辊旋转以实现非常高的准确度的纸张的供纸。用于打印机的送纸装置包括由步进电机构成的供纸马达，由供纸马达驱动旋转的马达齿轮，设置用于转动以便将记录纸传送到打印位置的供纸辊，供纸辊的外周设定为N线进给距离，用于驱动供纸辊旋转的进纸齿轮，至少一个用于将马达齿轮的旋转力传递到进纸齿轮的传动齿轮，检测元件形成在供纸辊上并指示供纸辊的基准位置，用于检测检测元件并产生检测信号的检测器，以及用于从检测器接收检测信号并控制纸张驱动的控制装置进给马达，使得在开始进纸时，供纸辊可以正常地定位在参考位置。

9. 发明授权

US4923857A 3-Alkenyl-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid compounds 失效
标题翻译： 3-烯基-1-氮杂双环（3.2.0）庚-2-烯-2-羧酸化合物
公开(公告)号：US4923857A
公开(公告)日：1990-05-08
申请号：US312061
申请日：1989-02-17
申请人： Masayoshi Murata , Toshiyuki Chiba , Akira Yamada
发明人： Masayoshi Murata , Toshiyuki Chiba , Akira Yamada
IPC分类号： C07D477/00 , A61K31/397 , A61K31/40 , A61P31/04 , C07D477/14
CPC分类号： C07D477/14
摘要： The invention relates to an antimicrobial compound of the formula: ##STR1## in which R.sup.1 is carboxy or protected carboxy,R.sup.2 is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl,R.sup.3 and R.sup.4 are each hydrogen or lower alkyl, andR.sup.5 is saturated 4 to 6-membered heteromonocyclic group containing 1 to 4 nitrogen atom(s), saturated 5 or 6-membered heteromonocyclic group containing 1 to 2 oxygen atom(s) and 1 to 3 nitrogen atom(s) or saturated 5 or 6-membered heteromonocyclic group containing 1 to 2 sulfur atom(s) and 1 to 3 nitrogen atom(s), wherein said aliphatic heterocyclic group may be substituted by one or more suitable substituent(s) selected from a group consisting of hydroxy, protected hydroxy, hydroxy(lower)alkyl, protected hydroxy(lower)alkyl, halogen, lower alkoxy, lower alkyl, lower alkoxy(lower)alkyl, imino, protected imino, lower alkylamino, protected lower alkylamino, mono(or di)-(lower)alkylcarbamoyloxy, lower alkylidene, lower alkanimidoyl and imino-protective group, or pharmaceutically acceptable salts thereof.

10. 发明授权

US4507293A Antimicrobial cephem compounds 失效
标题翻译：抗微生物头孢烯化合物
公开(公告)号：US4507293A
公开(公告)日：1985-03-26
申请号：US504428
申请日：1983-06-15
申请人： Takao Takaya , Hisashi Takasugi , Toshiyuki Chiba , Kiyoshi Tsuji
发明人： Takao Takaya , Hisashi Takasugi , Toshiyuki Chiba , Kiyoshi Tsuji
IPC分类号： C07D501/20 , C07D501/59
CPC分类号： C07D501/59
摘要： The invention relates to novel cephem compounds, of antimicrobial activity, of the formula ##STR1## wherein R.sup.1 is amino or protected amino,R.sup.2 is carboxy(lower)alkyl or protected carboxy(lower)alkyl,R.sup.3 is lower alkoxy, andR.sup.4 is carboxy or protected carboxy,and a pharmaceutically acceptable salt thereof.
摘要翻译：本发明涉及抗微生物活性的新颖的头孢烯化合物，其中R1是氨基或被保护的氨基，R2是羧基（低级）烷基或被保护的羧基（低级）烷基，R3是低级烷氧基，R4是羧基或保护的羧基及其药学上可接受的盐。

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