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1. 发明申请

US20080182854A1 4-Amino-5-Cyanopyrimidine Derivatives 有权
标题翻译： 4-氨基-5-氰基嘧啶衍生物
公开(公告)号：US20080182854A1
公开(公告)日：2008-07-31
申请号：US11579067
申请日：2005-04-28
申请人： Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
发明人： Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
IPC分类号： A61K31/506 , C07D401/12 , C07D401/14 , A61P27/06 , A61P27/02
CPC分类号： C07D401/14 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要： The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor agonistic activity; and also provides an adenosine A2a receptor agonist, an intraocular pressure reducing agent, or a medicine for treating glaucoma, etc., which comprises the compound as an active ingredient.
摘要翻译：本发明提供下式的4-氨基-5-氰基嘧啶衍生物：其中R 1，R 2和R 3 3定义如下，其药学上可接受的盐具有安全有效的腺苷A2a受体激动活性; 并且还提供了包含该化合物作为有效成分的腺苷A2a受体激动剂，眼内压降低剂或治疗青光眼的药物等。

2. 发明授权

US07989446B2 4-amino 5-cyanopyrimidine derivatives 有权
标题翻译： 4-氨基-5-氰基嘧啶衍生物
公开(公告)号：US07989446B2
公开(公告)日：2011-08-02
申请号：US12923451
申请日：2010-09-22
申请人： Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
发明人： Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
IPC分类号： C07D401/12 , C07D401/14 , A61K31/506
CPC分类号： C07D401/14 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要： The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor agonistic activity; and also provides an adenosine A2a receptor agonist, an intraocular pressure reducing agent, or a medicine for treating glaucoma, etc., which comprises the compound as an active ingredient.
摘要翻译：本发明提供下式的4-氨基-5-氰基嘧啶衍生物：其中R1，R2和R3在本文中定义，或其药学上可接受的盐，具有安全有效的腺苷A2a受体激动活性; 并且还提供了包含该化合物作为有效成分的腺苷A2a受体激动剂，眼内压降低剂或治疗青光眼的药物等。

3. 发明授权

US07834002B2 4-amino-5-cyanopyrimidine derivatives 有权
标题翻译： 4-氨基-5-氰基嘧啶衍生物
公开(公告)号：US07834002B2
公开(公告)日：2010-11-16
申请号：US11579067
申请日：2005-04-28
申请人： Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
发明人： Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
IPC分类号： C07D401/12 , C07D401/14 , C07D405/14 , A61K31/506
CPC分类号： C07D401/14 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要： The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor agonistic activity; and also provides an adenosine A2a receptor agonist, an intraocular pressure reducing agent, or a medicine for treating glaucoma, etc., which comprises the compound as an active ingredient.
摘要翻译：本发明提供下式的4-氨基-5-氰基嘧啶衍生物：其中R1，R2和R3在本文中定义，或其药学上可接受的盐，具有安全有效的腺苷A2a受体激动活性; 并且还提供了包含该化合物作为有效成分的腺苷A2a受体激动剂，眼内压降低剂或治疗青光眼的药物等。

4. 发明申请

US20110009620A1 4-Amino-5-cyanopyrimidine derivatives 有权
标题翻译： 4-氨基-5-氰基嘧啶衍生物
公开(公告)号：US20110009620A1
公开(公告)日：2011-01-13
申请号：US12923451
申请日：2010-09-22
申请人： Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
发明人： Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
IPC分类号： C07D401/14 , C07D401/12 , C07D413/14 , C07D417/14
CPC分类号： C07D401/14 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要： The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor agonistic activity; and also provides an adenosine A2a receptor agonist, an intraocular pressure reducing agent, or a medicine for treating glaucoma, etc., which comprises the compound as an active ingredient.
摘要翻译：本发明提供下式的4-氨基-5-氰基嘧啶衍生物：其中R1，R2和R3在本文中定义，或其药学上可接受的盐，具有安全有效的腺苷A2a受体激动活性; 并且还提供了包含该化合物作为有效成分的腺苷A2a受体激动剂，眼内压降低剂或治疗青光眼的药物等。

5. 发明授权

US08637559B2 Oxazole compound and pharmaceutical composition 有权
标题翻译：恶唑化合物和药物组合物
公开(公告)号：US08637559B2
公开(公告)日：2014-01-28
申请号：US12090951
申请日：2006-11-14
申请人： Minoru Okada , Masaya Kato , Norifumi Sato , Tetsuyuki Uno , Hideki Kitagaki , Junpei Haruta , Hidetaka Hiyama , Tomonori Shibata
发明人： Minoru Okada , Masaya Kato , Norifumi Sato , Tetsuyuki Uno , Hideki Kitagaki , Junpei Haruta , Hidetaka Hiyama , Tomonori Shibata
IPC分类号： A61K31/5377 , A61K31/497 , A61K31/496 , A61K31/4709 , A61K31/4439 , A61K31/422 , A61K31/421 , C07D413/12 , C07D413/06 , C07D263/32
CPC分类号： A61K31/421 , A61K31/4439 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/5377 , C07D263/32 , C07D263/34 , C07D413/06 , C07D413/12 , C12N9/16 , C12Y301/04012
摘要： The present invention provides a oxazole compound represented by Formula (1), or a salt thereof: wherein R1 is an aryl group which may have one or more substituents; R2 is an aryl group or a nitrogen atom-containing heterocyclic group each of which may have one or more substituents; and W is a divalent group represented by —Y1-A1- or —Y2—C(═O)— wherein Y1 is a group such as —C(═O)—, A1 is a group such as a lower alkylene group, and Y2 is a group such as a piperazinediyl group. The oxazole compound has a specific inhibitory action against phosphodiesterase 4.
摘要翻译：本发明提供由式（1）表示的恶唑化合物或其盐：其中R 1为可具有一个或多个取代基的芳基; R2是含有一个或多个取代基的芳基或含氮原子的杂环基; W为由-Y1-A1-或-Y2-C（= O）表示的二价基团，其中Y1为-C（= O） - ，A1为低级亚烷基等基团， Y2是哌嗪二基等基团。恶唑化合物对磷酸二酯酶4具有特异性的抑制作用。

6. 发明申请

US20090221586A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION 有权
标题翻译：奥沙唑化合物和药物组合物
公开(公告)号：US20090221586A1
公开(公告)日：2009-09-03
申请号：US12090951
申请日：2006-11-14
申请人： Minoru Okada , Masaya Kato , Norifumi Sato , Tetsuyuki Uno , Hideki Kitagaki , Junpei Haruta , Hidetaka Hiyama , Tomonori Shibata
发明人： Minoru Okada , Masaya Kato , Norifumi Sato , Tetsuyuki Uno , Hideki Kitagaki , Junpei Haruta , Hidetaka Hiyama , Tomonori Shibata
IPC分类号： A61K31/5377 , A61K31/497 , A61K31/4439 , A61K31/421 , C07D413/12 , C07D263/34
CPC分类号： A61K31/421 , A61K31/4439 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/5377 , C07D263/32 , C07D263/34 , C07D413/06 , C07D413/12 , C12N9/16 , C12Y301/04012
摘要： The present invention provides a oxazole compound represented by Formula (1), or a salt thereof: wherein R1 is an aryl group which may have one or more substituents; R2 is an aryl group or a nitrogen atom-containing heterocyclic group each of which may have one or more substituents; and W is a divalent group represented by —Y1-A1- or —Y2—C(═O)— wherein Y1 is a group such as —C(═O)—, A1 is a group such as a lower alkylene group, and Y2 is a group such as a piperazinediyl group. The oxazole compound has a specific inhibitory action against phosphodiesterase 4.
摘要翻译：本发明提供由式（1）表示的恶唑化合物或其盐：其中R 1为可具有一个或多个取代基的芳基; R2是含有一个或多个取代基的芳基或含氮原子的杂环基; W是由-Y1-A1-或-Y2-C（-O） - 表示的二价基团，其中Y1是-C（-O） - ，A1是低级亚烷基等基团， Y2是哌嗪二基等基团。恶唑化合物对磷酸二酯酶4具有特异性的抑制作用。

7. 发明申请

US20140016233A1 MULTILAYER FILM, MAGNETIC HEAD, MAGNETIC HEAD DEVICE, MAGNETIC RECORDING/REPRODUCING APPARATUS AND METHOD FOR MANUFACTURING MULTILAYER FILM 有权
标题翻译：多层膜，磁头，磁头装置，磁记录/再现装置和制造多层膜的方法
公开(公告)号：US20140016233A1
公开(公告)日：2014-01-16
申请号：US13548715
申请日：2012-07-13
申请人： Masaya Kato , Atsushi Yamaguchi
发明人： Masaya Kato , Atsushi Yamaguchi
IPC分类号： G11B5/48 , C25D5/18 , G11B5/33
CPC分类号： G11B5/3967 , C25D3/562 , C25D5/14 , C25D5/18 , C25D7/001 , G11B5/3912
摘要： In the present invention, magnetic and non-magnetic films are formed as a compound of Fe, Ni and P to provide a multilayer film in which such magnetic and non-magnetic films are alternately stacked.The multilayer film includes a magnetic film and a non-magnetic film. The magnetic film and the non-magnetic film are alternately stacked. The magnetic film contains Fe, Ni and P but has Fe as a main component. The magnetic film contains Fe, Ni and P but has Fe or Ni as a main component. The non-magnetic film contains Fe, Ni and P but has Ni as a main component.
摘要翻译：在本发明中，作为Fe，Ni和P的化合物形成磁性和非磁性膜，以提供交替堆叠这种磁性和非磁性膜的多层膜。多层膜包括磁性膜和非磁性膜。磁性膜和非磁性膜交替堆叠。磁性膜含有Fe，Ni和P，但以Fe为主要成分。磁性膜含有Fe，Ni和P，但以Fe或Ni为主要成分。非磁性膜含有Fe，Ni和P，但以Ni为主要成分。

8. 发明授权

US08248728B2 Thin-film magnetic head having a magnetic pole formed of a plating film 有权
标题翻译：具有由镀膜形成的磁极的薄膜磁头
公开(公告)号：US08248728B2
公开(公告)日：2012-08-21
申请号：US12697699
申请日：2010-02-01
申请人： Atsushi Yamaguchi , Masaya Kato , Koichi Otani , Wakako Okawa
发明人： Atsushi Yamaguchi , Masaya Kato , Koichi Otani , Wakako Okawa
IPC分类号： G11B5/147
CPC分类号： G11B5/33 , G11B21/02 , Y10T428/1171
摘要： A magnetic pole of a magnetic head includes a narrow and a wide portion, and is formed of a plating film. An electrode film forms the plating film, and is provided only under at least a part of the wide portion. A manufacturing method for the magnetic head includes: forming a plating-film-accommodating layer with an accommodating groove; forming the electrode film in part of the accommodating groove; and forming the plating film in the accommodating groove by plating using the electrode film. The accommodating groove includes a narrow and a wide groove portion for accommodating the narrow and wide portions, respectively. The electrode film is provided only in at least a part of the wide groove portion. In the step of forming the plating film, the plating film grows from the surface of the electrode film, and the narrow groove portion is filled with a part of the plating film.
摘要翻译：磁头的磁极包括窄且宽的部分，并且由镀膜形成。电极膜形成镀膜，并且仅在宽部的至少一部分下方设置。磁头的制造方法包括：形成具有容纳槽的镀膜容纳层; 在所述容纳槽的一部分中形成所述电极膜; 以及通过使用所述电极膜进行电镀而在所述容纳槽中形成所述镀膜。容纳槽包括狭窄的宽槽部分，用于分别容纳狭窄和宽的部分。电极膜仅设置在宽槽部的至少一部分中。在形成镀膜的步骤中，电镀膜从电极膜的表面生长，并且窄槽部分填充有电镀膜的一部分。

9. 发明授权

US08164853B2 Perpendicular magnetic write head with side shield saturation magnetic flux density increasing away from magnetic pole 有权
标题翻译：垂直磁写头，侧面屏蔽饱和磁通密度从磁极增加
公开(公告)号：US08164853B2
公开(公告)日：2012-04-24
申请号：US12719451
申请日：2010-03-08
申请人： Kei Hirata , Atsushi Yamaguchi , Masaya Kato , Hideyuki Ukita , Kenkichi Anagawa , Minoru Ota
发明人： Kei Hirata , Atsushi Yamaguchi , Masaya Kato , Hideyuki Ukita , Kenkichi Anagawa , Minoru Ota
IPC分类号： G11B5/10 , G11B5/31
CPC分类号： G11B5/315 , G11B5/1278
摘要： A perpendicular magnetic write head is provided with a magnetic pole and a pair of side shields disposed on both sides of the magnetic pole in a cross track direction with side gaps in between. Each of the pair of side shields is configured in such a manner that a saturation magnetic flux density thereof increases as a distance from the magnetic pole in the cross track direction increases. Such a configuration allows unwanted divergence component of magnetic flux in a recording magnetic field to be captured while avoiding any excessive capturing of the recording magnetic field, and while preventing any intensity reduction of the recording magnetic field in its entirety. As a result, the recording magnetic field is maintained to have an adequate intensity and spreading of the recording magnetic field is suppressed, so that the recording capabilities are improved.
摘要翻译：垂直磁性写头设置有磁极和一对侧屏蔽件，其设置在磁极的两侧上，并且在横向方向上具有侧间隙。一对侧面屏蔽中的每一个被构造成使得其饱和磁通密度随着在横向上的磁极的距离增加而增加。这样的配置允许在避免记录磁场的任何过度捕获的同时捕获记录磁场中的磁通量的不期望的发散分量，并且同时防止整个记录磁场的强度降低。结果，记录磁场被保持为具有足够的强度，并且抑制了记录磁场的扩展，从而提高了记录能力。

10. 发明申请

US20110216443A1 PERPENDICULAR MAGNETIC WRITE HEAD AND MAGNETIC RECORDING DEVICE 有权
标题翻译：全磁性写磁头和磁记录装置
公开(公告)号：US20110216443A1
公开(公告)日：2011-09-08
申请号：US12719451
申请日：2010-03-08
申请人： Kei Hirata , Atsushi Yamaguchi , Masaya Kato , Hideyuki Ukita , Kenkichi Anagawa , Minoru Ota
发明人： Kei Hirata , Atsushi Yamaguchi , Masaya Kato , Hideyuki Ukita , Kenkichi Anagawa , Minoru Ota
IPC分类号： G11B5/10
CPC分类号： G11B5/315 , G11B5/1278
摘要： A perpendicular magnetic write head is provided with a magnetic pole and a pair of side shields disposed on both sides of the magnetic pole in a cross track direction with side gaps in between. Each of the pair of side shields is configured in such a manner that a saturation magnetic flux density thereof increases as a distance from the magnetic pole in the cross track direction increases. Such a configuration allows unwanted divergence component of magnetic flux in a recording magnetic field to be captured while avoiding any excessive capturing of the recording magnetic field, and while preventing any intensity reduction of the recording magnetic field in its entirety. As a result, the recording magnetic field is maintained to have an adequate intensity and spreading of the recording magnetic field is suppressed, so that the recording capabilities are improved.
摘要翻译：垂直磁性写头设置有磁极和一对侧屏蔽件，其设置在磁极的两侧上，并且在横向方向上具有侧间隙。一对侧面屏蔽中的每一个被构造成使得其饱和磁通密度随着在横向上的磁极的距离增加而增加。这样的配置允许在避免记录磁场的任何过度捕获的同时捕获记录磁场中的磁通量的不期望的发散分量，并且同时防止整个记录磁场的强度降低。结果，记录磁场被保持为具有足够的强度，并且抑制了记录磁场的扩展，从而提高了记录能力。

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