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1. 发明申请

US20100317836A1 NOVEL BIOLOGICAL SUBSTANCE NESFATIN AND ITS RELATED SUBSTANCES AND USES THEREOF 失效
标题翻译：新生物质NESFATIN及其相关物质及其用途
公开(公告)号：US20100317836A1
公开(公告)日：2010-12-16
申请号：US12838760
申请日：2010-07-19
申请人： Masatomo MORI , Hiroyuki Shimizu , Hiroshi Eguchi , Masanori Yamamoto
发明人： Masatomo MORI , Hiroyuki Shimizu , Hiroshi Eguchi , Masanori Yamamoto
IPC分类号： C07K16/00
CPC分类号： C12Q1/6883 , A01K67/027 , A01K2227/105 , A01K2267/035 , C07K14/4702 , C12Q2600/158 , G01N33/5023 , G01N2800/02 , G01N2800/044
摘要： The present invention relates to a novel method of obtaining a factor involved in appetite control and/or body weight control, as well as genes obtained by said method, polypeptides encoded by said genes, or novel polypeptides obtained from the information on polypeptides encoded by said genes as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control. Also the present invention relates to substances that inhibit the effects of said genes or said polypeptides as a means for treating, controlling or diagnosing diseases associated with appetite control and/or body weight control. By using thiazolidine diones having a PPAR γ agonist activity, genes and polypeptides involved in appetite regulation and/or body weight reduction can be obtained. NESFATIN or the like obtained by said method can be used as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control.
摘要翻译：本发明涉及一种获得涉及食欲控制和/或体重控制的因子的新方法，以及通过所述方法获得的基因，由所述基因编码的多肽或从由所述基因编码的多肽编码的信息获得的新多肽基因作为治疗，控制或诊断与进食障碍和/或体重控制相关的疾病的手段。本发明还涉及抑制所述基因或所述多肽作为治疗，控制或诊断与食欲控制和/或体重控制相关的疾病的手段的物质。通过使用具有PPARγ激动剂活性的噻唑烷二酮，可以获得参与食欲调节和/或体重减轻的基因和多肽。通过所述方法获得的NESFATIN等可以用作治疗，控制或诊断与进食障碍和/或体重控制相关的疾病的手段。

2. 发明授权

US08383119B2 Biological substance nesfatin and its related substances and uses thereof 失效
标题翻译：生物物质nesfatin及其相关物质及其用途
公开(公告)号：US08383119B2
公开(公告)日：2013-02-26
申请号：US12838760
申请日：2010-07-19
申请人： Masatomo Mori , Hiroyuki Shimizu , Hiroshi Eguchi , Masanori Yamamoto
发明人： Masatomo Mori , Hiroyuki Shimizu , Hiroshi Eguchi , Masanori Yamamoto
IPC分类号： A61K39/395 , A61K39/00 , A61K38/17 , C07K16/18 , C07K16/26
CPC分类号： C12Q1/6883 , A01K67/027 , A01K2227/105 , A01K2267/035 , C07K14/4702 , C12Q2600/158 , G01N33/5023 , G01N2800/02 , G01N2800/044
摘要： The present invention relates to a novel method of obtaining a factor involved in appetite control and/or body weight control, as well as genes obtained by said method, polypeptides encoded by said genes, or novel polypeptides obtained from the information on polypeptides encoded by said genes as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control. Also the present invention relates to substances that inhibit the effects of said genes or said polypeptides as a means for treating, controlling or diagnosing diseases associated with appetite control and/or body weight control. By using thiazolidine diones having a PPAR γ agonist activity, genes and polypeptides involved in appetite regulation and/or body weight reduction can be obtained. NESFATIN or the like obtained by said method can be used as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control.
摘要翻译：本发明涉及一种获得涉及食欲控制和/或体重控制的因子的新方法，以及通过所述方法获得的基因，由所述基因编码的多肽或从由所述基因编码的多肽编码的信息获得的新多肽基因作为治疗，控制或诊断与进食障碍和/或体重控制相关的疾病的手段。本发明还涉及抑制所述基因或所述多肽作为治疗，控制或诊断与食欲控制和/或体重控制相关的疾病的手段的物质。通过使用具有PPARγ激动剂活性的噻唑烷二酮，可以获得参与食欲调节和/或体重减轻的基因和多肽。通过所述方法获得的NESFATIN等可以用作治疗，控制或诊断与进食障碍和/或体重控制相关的疾病的手段。

3. 发明授权

US07795390B2 Biological substance nesfatin and its related substances and uses thereof 失效
标题翻译：生物物质nesfatin及其相关物质及其用途
公开(公告)号：US07795390B2
公开(公告)日：2010-09-14
申请号：US11474282
申请日：2006-06-26
申请人： Masatomo Mori , Hiroyuki Shimizu , Hiroshi Eguchi , Masanori Yamamoto
发明人： Masatomo Mori , Hiroyuki Shimizu , Hiroshi Eguchi , Masanori Yamamoto
IPC分类号： C12N9/00 , C12N1/20 , C12N15/00 , C07K14/00 , C07H21/02
CPC分类号： C12Q1/6883 , A01K67/027 , A01K2227/105 , A01K2267/035 , C07K14/4702 , C12Q2600/158 , G01N33/5023 , G01N2800/02 , G01N2800/044
摘要： The present invention relates to a novel method of obtaining a factor involved in appetite control and/or body weight control, as well as genes obtained by said method, polypeptides encoded by said genes, or novel polypeptides obtained from the information on polypeptides encoded by said genes as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control. Also the present invention relates to substances that inhibit the effects of said genes or said polypeptides as a means for treating, controlling or diagnosing diseases associated with appetite control and/or body weight control. By using thiazolidine diones having a PPAR γ agonist activity, genes and polypeptides involved in appetite regulation and/or body weight reduction can be obtained. NESFATIN or the like obtained by said method can be used as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control.
摘要翻译：本发明涉及一种获得涉及食欲控制和/或体重控制的因子的新方法，以及通过所述方法获得的基因，由所述基因编码的多肽或从由所述基因编码的多肽编码的信息获得的新多肽基因作为治疗，控制或诊断与进食障碍和/或体重控制相关的疾病的手段。本发明还涉及抑制所述基因或所述多肽作为治疗，控制或诊断与食欲控制和/或体重控制相关的疾病的手段的物质。通过使用具有PPARγ激动剂活性的噻唑烷二酮，可以获得参与食欲调节和/或体重减轻的基因和多肽。通过所述方法获得的NESFATIN等可以用作治疗，控制或诊断与进食障碍和/或体重控制相关的疾病的手段。

4. 发明申请

US20080115231A1 Novel biological substance nesfatin and its related substances and uses thereof 失效
标题翻译：新型生物物质nesfatin及其相关物质及其用途
公开(公告)号：US20080115231A1
公开(公告)日：2008-05-15
申请号：US11474282
申请日：2006-06-26
申请人： Masatomo Mori , Hiroyuki Shimizu , Hiroshi Eguchi , Masanori Yamamoto
发明人： Masatomo Mori , Hiroyuki Shimizu , Hiroshi Eguchi , Masanori Yamamoto
IPC分类号： A01K67/027 , C12Q1/68 , C07H21/04 , C12P21/06 , C07K14/705
CPC分类号： C12Q1/6883 , A01K67/027 , A01K2227/105 , A01K2267/035 , C07K14/4702 , C12Q2600/158 , G01N33/5023 , G01N2800/02 , G01N2800/044
摘要： The present invention relates to a novel method of obtaining a factor involved in appetite control and/or body weight control, as well as genes obtained by said method, polypeptides encoded by said genes, or novel polypeptides obtained from the information on polypeptides encoded by said genes as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control. Also the present invention relates to substances that inhibit the effects of said genes or said polypeptides as a means for treating, controlling or diagnosing diseases associated with appetite control and/or body weight control. By using thiazolidine diones having a PPAR γ agonist activity, genes and polypeptides involved in appetite regulation and/or body weight reduction can be obtained. NESFATIN or the like obtained by said method can be used as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control.
摘要翻译：本发明涉及一种获得涉及食欲控制和/或体重控制的因子的新方法，以及通过所述方法获得的基因，由所述基因编码的多肽或从由所述基因编码的多肽编码的信息获得的新多肽基因作为治疗，控制或诊断与进食障碍和/或体重控制相关的疾病的手段。本发明还涉及抑制所述基因或所述多肽作为治疗，控制或诊断与食欲控制和/或体重控制相关的疾病的手段的物质。通过使用具有PPARγ激动剂活性的噻唑烷二酮，可以获得参与食欲调节和/或体重减轻的基因和多肽。通过所述方法获得的NESFATIN等可以用作治疗，控制或诊断与进食障碍和/或体重控制相关的疾病的手段。

5. 发明申请

US20110110949A1 NESFATIN-1 SPECIFIC ANTIBODY AND THE USE THEREOF, AND NESFATIN SPECIFIC ANTIBODY AND THE USE THEREOF 审中-公开
标题翻译： NESFATIN-1特异性抗体及其用途及其特异性抗体及其用途
公开(公告)号：US20110110949A1
公开(公告)日：2011-05-12
申请号：US12674902
申请日：2008-08-25
申请人： Masatomo Mori , Hiroyuki Shimizu , Hiroshi Eguchi , Takashi Kawamura
发明人： Masatomo Mori , Hiroyuki Shimizu , Hiroshi Eguchi , Takashi Kawamura
IPC分类号： A61K39/395 , C07K16/00 , C12N5/16 , G01N33/566 , A61P3/00
CPC分类号： C07K16/26 , C07K16/18 , G01N33/566
摘要： The present application relates to an antibody performing an antigen-antibody reaction with Nesfatin-1, but not substantially performing the antigen-antibody reaction with Nesfatin and/or NucB1, and with the use of the antibody, an immunological detection method and a detection kit of Nesfatin-1, and further, an antibody performing an antigen-antibody reaction with Nesfatin, but not substantially performing the antigen-antibody reaction with NucB1, and an immunological detection method using the antibody, and a detection kit of Nesfatin comprising the antibody.
摘要翻译：本申请涉及与Nesfatin-1进行抗原 - 抗体反应的抗体，但实质上不进行与Nesfatin和/或NucB1的抗原 - 抗体反应，并且使用抗体，免疫检测方法和检测试剂盒的Nesfatin-1，进一步，与Nesfatin进行抗原抗体反应，但基本上不进行与NucB1的抗原 - 抗体反应的抗体，以及使用该抗体的免疫检测方法，以及含有该抗体的Nesfatin检测试剂盒。

6. 发明授权

US09409313B2 Concrete mixer truck 有权
标题翻译：混凝土搅拌车
公开(公告)号：US09409313B2
公开(公告)日：2016-08-09
申请号：US13546114
申请日：2012-07-11
申请人： Hiroyuki Shimizu
发明人： Hiroyuki Shimizu
IPC分类号： B28C5/42 , B28C7/02 , B28C7/12
CPC分类号： B28C5/422 , B28C7/026 , B28C7/12
摘要： A concrete mixer truck includes: a driving device that drives a mixer drum to rotate; a pressure sensor that detects a pressure of the working fluid in the driving device; a material introduction determination unit that determines whether or not a material for generating the mixed concrete has been introduced into the mixer drum; a pressure determination unit that determines whether or not the pressure of the working fluid detected by the pressure sensor has fallen to a set pressure set in advance in accordance with a carrying amount and a fluidity of the mixed concrete after the introduction of the materials for the mixed concrete into the mixer drum; and a notification device that notifies an operator that the pressure of the working fluid in the driving device has fallen to the set pressure on the basis of the determination made by the pressure determination unit.
摘要翻译：混凝土搅拌车包括：驱动搅拌筒旋转的驱动装置; 检测所述驱动装置内的工作流体的压力的压力传感器; 材料介绍确定单元，其确定用于产生混合混凝土的材料是否被引入到混合器鼓中; 压力确定单元，其确定由压力传感器检测到的工作流体的压力是否已经下降到预先设定的设定压力之后，根据混合混凝土的承载量和流动性，在引入用于将混凝土搅拌成混合器; 以及通知装置，其基于由压力确定单元做出的确定通知操作者驱动装置中的工作流体的压力已经下降到设定压力。

7. 发明授权

US08542974B2 Portable information terminal apparatus, information processing method, computer-program storage medium 有权
标题翻译：便携式信息终端装置，信息处理方法，计算机程序存储介质
公开(公告)号：US08542974B2
公开(公告)日：2013-09-24
申请号：US13433840
申请日：2012-03-29
申请人： Koji Kunii , Masaki Takase , Hiroyuki Shimizu
发明人： Koji Kunii , Masaki Takase , Hiroyuki Shimizu
IPC分类号： H04N5/932
CPC分类号： G08C23/04 , H04H60/09 , H04H60/27 , H04H60/72 , H04H60/80 , H04H60/85 , H04H60/91 , H04N21/4126 , H04N21/47214 , H04N21/812
摘要： A portable information terminal apparatus generates a first signal, based on the user's operation, that causes a recording/reproducing apparatus to acquire program information. A second signal based on the user's operation, causes the recording/reproducing apparatus to display the acquired program information. A third signal based on the user's operation causes the recording/reproducing apparatus to preset the program for unattended recording. A fourth signal based on the user's operation causes the recording/reproducing apparatus to convert the recorded program to video data in a predetermined file format.
摘要翻译：便携式信息终端装置根据用户的操作生成使记录/再现装置获取节目信息的第一信号。基于用户操作的第二信号使得记录/再现设备显示所获取的节目信息。基于用户操作的第三信号使记录/再现设备预设用于无人值守记录的程序。基于用户的操作的第四信号使得记录/再现装置将所记录的节目转换为预定文件格式的视频数据。

8. 发明申请

US20120229953A1 LEAD-FREE PIEZOELECTRIC PORCELAIN COMPOSITION, PIEZOELECTRIC CERAMIC COMPONENT FORMED USING THE COMPOSITION, AND PROCESS FOR PRODUCING PIEZOELECTRIC CERAMIC COMPONENT 审中-公开
标题翻译：无铅压电陶瓷组合物，使用该组合物成型的压电陶瓷组分和用于生产压电陶瓷组分的方法
公开(公告)号：US20120229953A1
公开(公告)日：2012-09-13
申请号：US13510261
申请日：2010-09-21
申请人： Keiichi Hatano , Keisuke Kobayashi , Tomoya Hagiwara , Hiroyuki Shimizu , Yutaka Doshida
发明人： Keiichi Hatano , Keisuke Kobayashi , Tomoya Hagiwara , Hiroyuki Shimizu , Yutaka Doshida
IPC分类号： H01L41/187 , H01G4/12 , H01L41/22
CPC分类号： H03H9/02031 , C04B35/495 , C04B2235/3201 , C04B2235/3203 , C04B2235/3251 , C04B2235/3294 , C04B2235/442 , C04B2235/76 , C04B2235/765 , C04B2235/768 , C04B2235/79 , H01G4/12 , H01L41/1873 , H01L41/43 , H03H9/02543 , H03H9/178 , Y10T29/42
摘要： Provided is an alkali-niobate-based piezoelectric porcelain composition which has a crystal-structure transition point in the range of operation guarantee temperatures and which, despite this, is inhibited from abruptly changing in capacitance. The piezoelectric porcelain composition comprises Li, Na, K, Nb, Ta, Sb, and O as major constituent elements and has an alkali-niobate-based perovskite structure. When the composition has an ABO3 type perovskite structure as a unit lattice in which Z=1, the composition has a transition point at which the crystal structure changes from the monoclinic to the tetragonal system. Thus, the composition has a crystal-structure transition point at −50° C. to 150° C. so as to utilize the high piezoelectric effect produced by the MPB at the crystal-structure transition point and, despite this, has the feature of always satisfying ΔC>0.
摘要翻译：本发明提供一种碱铌酸盐系压电陶瓷组合物，其具有晶体结构转变点在操作保证温度的范围内，尽管如此，其抑制了电容的突然变化。压电瓷组合物包含Li，Na，K，Nb，Ta，Sb和O作为主要组成元素，并具有铌酸酯基钙钛矿结构。当组合物具有作为Z = 1的单位晶格的ABO 3型钙钛矿结构时，组成具有晶体结构从单斜晶向四方晶系变化的转变点。因此，组合物在-50℃至150℃具有晶体结构转变点，以利用在晶体结构转变点由MPB产生的高压电效应，并且尽管如此，具有总是满足＆Dgr; C> 0。

9. 发明申请

US20070106767A1 DATABASE DEVICE DATABASE SEARCH DEVICE, AND METHOD THEREOF 审中-公开
标题翻译：数据库设备数据库搜索设备及其方法
公开(公告)号：US20070106767A1
公开(公告)日：2007-05-10
申请号：US10554365
申请日：2004-04-23
申请人： Akio Yamamoto , Shinya Nakagawa , Hiroyuki Shimizu
发明人： Akio Yamamoto , Shinya Nakagawa , Hiroyuki Shimizu
IPC分类号： G06F15/173
CPC分类号： G06F16/288 , G06F16/9024
摘要： There is provided a database server capable of easily adding various kinds of associated data without modifying the structure of the database. A heading node (T node) is correlated with an associated node (A node) and an association role R is defined between the T node and the A node associated with it. Furthermore, each of the T node and the A node is added with an identifier (ID), its attribute (node type), and a name (node name). The data having such a structure is stored in an association/role table (AR table) composed of an entry containing ID of the A node and T node associated with each other and the association role R defined between them and in an identifier table (ID table) containing the ID, attribute, and name of the A node and the T node, so that the data can be searched.
摘要翻译：提供了能够容易地添加各种关联数据而不修改数据库的结构的数据库服务器。标题节点（T节点）与关联节点（A节点）相关联，并且在T节点和与其相关联的A节点之间定义关联角色R. 此外，T节点和A节点中的每一个都添加了标识符（ID），其属性（节点类型）和名称（节点名称）。具有这种结构的数据被存储在由包含彼此相关联的A节点和T节点的ID的条目组成的关联/角色表（AR表）中，以及在它们之间定义的关联角色R和标识符表（ID 表），其包含A节点和T节点的ID，属性和名称，以便可以搜索数据。

10. 发明申请

US20050149846A1 Apparatus, method, and program for text classification using frozen pattern 审中-公开
标题翻译：使用冻结图案进行文本分类的装置，方法和程序
公开(公告)号：US20050149846A1
公开(公告)日：2005-07-07
申请号：US10958598
申请日：2004-10-06
申请人： Hiroyuki Shimizu , Shinya Nakagawa
发明人： Hiroyuki Shimizu , Shinya Nakagawa
IPC分类号： G06F17/30 , G06F15/00 , G06F17/00 , G06F17/21 , G06F17/24 , G06F17/27 , G06N5/02
CPC分类号： G06F17/274
摘要： A document is classified by document style on the basis of textual analysis without depending upon morphological analysis. A style-specific frozen pattern is prepared as a reference dictionary for each document style. A frozen pattern list is extracted for an input document based on the basis of a state of appearance of a style-specific frozen pattern present in the document. Confidence for each document style is calculated based on the frozen pattern list and the detected style of the input document.
摘要翻译：文件根据文本分析而不依赖于形态分析，将文档分类。准备作为每个文档样式的参考字典的样式特定冻结模式。基于文档中存在的风格特定冻结模式的出现状态的基础，为输入文档提取冻结模式列表。基于冻结模式列表和检测到的输入文档的样式计算每种文档样式的置信度。

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