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    • 6. 发明授权
    • Blood filter cartridge
    • 血液滤芯
    • US06217540B1
    • 2001-04-17
    • US09349173
    • 1999-07-09
    • Kenichiro YazawaKeiichi IshizakiTakeshi IgarashiMasao KitajimaShigeru TezukaTakaki AraiToshihisa ItoOsamu Seshimoto
    • Kenichiro YazawaKeiichi IshizakiTakeshi IgarashiMasao KitajimaShigeru TezukaTakaki AraiToshihisa ItoOsamu Seshimoto
    • A61M3700
    • G01N33/491
    • The invention provides a blood filter cartridge which is made so that the filtrate discharged from the filtrate outlet is not drawn back to the inside of the filtering chamber. The blood filter cartridge includes a blood filtering material, a holder containing the blood filtering material and having a blood inlet and a filtrate outlet, and a filtrate receiver which receives the filtrate discharged from the filtrate outlet. The blood filter catridge is provided with a means for preventing the filtrate in the filtrate receiver from returning to inside of the holder upon finishing filtration. Such means include the following: removing opposite faces around the filtrate outlet, making length of lower end of the filtrate outlet 0.8 mm or more, smoothing surface around the filtrate outlet, and forming surface around the filtrate outlet by a material having a small surface energy.
    • 本发明提供了一种血液过滤器滤芯,其被制成使得从滤液出口排出的滤液不会被抽回到过滤室的内部。 血液过滤器滤芯包括血液过滤材料,含有血液过滤材料并具有血液入口和滤液出口的保持器和接收从滤​​液出口排出的滤液的滤液接收器。 血液过滤器夹具设置有用于防止滤液接收器中的滤液在完成过滤时返回到保持器内部的装置。 这样的方法包括以下步骤:除去滤液出口周围的相对面,使滤液出口的下端长度为0.8mm以上,使滤液出口周围的表面光滑,并且通过具有小表面能的材料在滤液出口周围形成表面 。
    • 8. 发明授权
    • Preparation of plasma or serum sample from whole blood
    • 从全血制备血浆或血清样品
    • US5876605A
    • 1999-03-02
    • US784480
    • 1997-01-17
    • Masao KitajimaKenichiro Yazawa
    • Masao KitajimaKenichiro Yazawa
    • G01N33/48G01N1/28G01N33/50B01D61/00
    • G01N33/491G01N33/5002Y10T436/25375Y10T436/255
    • The method of the invention is for preparing a plasma or serum sample from whole blood and includes mixing an aqueous solution of an inorganic salt or an amino acid or salt thereof with the whole blood in an amount of 20% or less of the whole blood volume so that concentration of the inorganic salt or the amino acid or salt thereof becomes 10 to 200 .mu.mol/1 ml whole blood, and then, filtering the whole blood to remove blood cell components. According to the method of the invention, plasma separation from whole blood can be achieved efficiently, and recovered volume of plasma can be increased. By selecting reagent, good plasma which has no deviation in component viewpoint, and which is possible to measure in the same level accuracy as a plasma obtained by centurifuging, can be obtained through a simple filtration operation.
    • 本发明的方法是从全血中制备血浆或血清样品,包括将无机盐或其氨基酸或其盐的水溶液与全血的全血量的20%或更少的量混合 使无机盐或其氨基酸或其盐的浓度成为10〜200μmol/ ml全血,然后过滤全血以除血细胞成分。 根据本发明的方法,能够有效地实现全血的血浆分离,能够提高等离子体的回收体积。 通过选择试剂,可以通过简单的过滤操作获得组分观点没有偏差的良好的等离子体,并且可以以与通过中间脱色获得的等离子体相同的精度测量。
    • 9. 发明授权
    • Analysis material sheet
    • 分析材料表
    • US4783315A
    • 1988-11-08
    • US758562
    • 1985-07-23
    • Fuminori AraiKenichiro YazawaHideaki TakeuchiMasao Kitajima
    • Fuminori AraiKenichiro YazawaHideaki TakeuchiMasao Kitajima
    • G01N31/22G01N33/52G01N33/66
    • G01N33/525Y10T428/31736Y10T428/3175
    • An analysis material sheet is disclosed which is comprised of layers of material with strong adhesion for one another. The sheet includes a water-impermeable support having provided directly or indirectly thereon a layer of fabric. The fabric contains a hydrophobic organic polymer fiber and is physically activated on at least one surface thereof, with the physically activated surface being adhered directly or indirectly to the support. A reagent layer can be provided directly or indirectly on the liquid sample-spreading layer of fabric. By utilizing a fabric containing a hydrophobic organic polymer fiber, body fluids to be analyzed can be quickly and uniformly spread and by utilizing the physically activated surface of the fabric, strong adhesion between the layers can be obtained.
    • 公开了一种分析材料片,其由彼此具有强粘合性的材料层组成。 片材包括直接或间接地在其上提供织物层的不透水支撑体。 织物含有疏水性有机聚合物纤维,并在其至少一个表面上物理活化,物理活化表面直接或间接地粘附到载体上。 试剂层可以直接或间接地提供在织物的液体样品铺展层上。 通过使用含有疏水性有机聚合物纤维的织物,可以快速且均匀地分散待分析的体液,并且通过利用织物的物理活化表面,可以获得层间的强粘合性。