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    • 4. 发明申请
    • PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND
    • 广泛形成氨基氧化合物和1,2-氧化合物的方法
    • US20110224429A1
    • 2011-09-15
    • US12782709
    • 2010-05-18
    • Guofu ZhongMin LuDi ZhuPei Juan ChuaBin Tan
    • Guofu ZhongMin LuDi ZhuPei Juan ChuaBin Tan
    • C07D265/02C07C209/38
    • C07D265/02C07C239/20
    • Disclosed is a process of enantioselectively forming an aminoxy compound of Formula (3) In formula (3) R1 is one of an aliphatic group and an alicyclic group. R2 is one of hydrogen, an aliphatic group, an alicyclic group, an aromatic group, an arylaliphatic group and an arylalicyclic group. R3 is one of hydrogen, halogen, hydroxyl, and an aliphatic group with a main chain having 1 to about 10 carbon atoms. The respective aliphatic, alicyclic, aromatic, arylaliphatic or arylalicyclic groups of R1, R2, and R3 comprise 0 to about 3 heteroatoms independently selected from the group consisting of N, O, S, Se and Si. The process includes contacting a carbonyl compound of Formula (1) and a nitroso compound of Formula (2) in the presence of a chiral catalyst. The chiral catalyst is a compound of Formula (IX)
    • 公开了对映选择性地形成式(3)的氨氧基化合物的方法。在式(3)中,R 1是脂族基和脂环基之一。 R2是氢,脂肪族基团,脂环族基团,芳香族基团,芳基脂族基团和芳基脂环族基团中的一种。 R 3是氢,卤素,羟基和具有1至约10个碳原子的主链的脂族基团之一。 R 1,R 2和R 3各自的脂族,脂环族,芳族,芳基脂族或芳基脂环基包含0至约3个独立地选自N,O,S,Se和Si的杂原子。 该方法包括在手性催化剂的存在下使式(1)的羰基化合物与式(2)的亚硝基化合物接触。 手性催化剂是式(IX)的化合物,
    • 6. 发明授权
    • Processes of enantioselectively forming an aminoxy compound and an 1,2-oxazine compound
    • 对映选择性形成氨氧基化合物和1,2-恶嗪化合物的方法
    • US08680335B2
    • 2014-03-25
    • US12782709
    • 2010-05-18
    • Guofu ZhongMin LuDi ZhuPei Juan ChuaBin Tan
    • Guofu ZhongMin LuDi ZhuPei Juan ChuaBin Tan
    • C07C209/38C07D265/02
    • C07D265/02C07C239/20
    • Disclosed is a process of enantioselectively forming an aminoxy compound of Formula (3) In formula (3) R1 is one of an aliphatic group and an alicyclic group. R2 is one of hydrogen, an aliphatic group, an alicyclic group, an aromatic group, an arylaliphatic group and an arylalicyclic group. R3 is one of hydrogen, halogen, hydroxyl, and an aliphatic group with a main chain having 1 to about 10 carbon atoms. The respective aliphatic, alicyclic, aromatic, arylaliphatic or arylalicyclic groups of R1, R2, and R3 comprise 0 to about 3 heteroatoms independently selected from the group consisting of N, O, S, Se and Si. The process includes contacting a carbonyl compound of Formula (1) and a nitroso compound of Formula (2) in the presence of a chiral catalyst. The chiral catalyst is a compound of Formula (IX)
    • 公开了对映选择性地形成式(3)的氨氧基化合物的方法。在式(3)中,R 1是脂族基和脂环基之一。 R2是氢,脂肪族基团,脂环族基团,芳香族基团,芳基脂族基团和芳基脂环族基团中的一种。 R 3是氢,卤素,羟基和具有1至约10个碳原子的主链的脂族基团之一。 R 1,R 2和R 3各自的脂族,脂环族,芳族,芳基脂族或芳基脂环基包含0至约3个独立地选自N,O,S,Se和Si的杂原子。 该方法包括在手性催化剂的存在下使式(1)的羰基化合物与式(2)的亚硝基化合物接触。 手性催化剂是式(IX)的化合物,