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1. 发明申请

US20070270706A1 Determination of sleep depth 有权
标题翻译：睡眠深度的确定
公开(公告)号：US20070270706A1
公开(公告)日：2007-11-22
申请号：US11438637
申请日：2006-05-22
申请人： Pekka Merilainen , Markku Paloheimo , Juha Virtanen , Hanna Viertio-Oja , Petteri Lapinlampi
发明人： Pekka Merilainen , Markku Paloheimo , Juha Virtanen , Hanna Viertio-Oja , Petteri Lapinlampi
IPC分类号： A61B5/04
CPC分类号： A61B5/0535 , A61B5/0484 , A61B5/0496 , A61B5/4812
摘要： The invention relates to a mechanism for determining the depth of sleep of a subject. In order to obtain information about the continuum of the depth of sleep in a user-friendly way without a need for high computational power, EEG signal data is obtained from a subject, REM sleep periods of the subject are detected, and a measure indicative of irregularity in the EEG signal data is derived. Based on the measure and the detected REM sleep periods, a sleep depth index and state information are produced, where the index is indicative of the depth of sleep of the subject and the state information indicates whether or not the EEG signal data is obtained during a REM sleep period. The detection of the REM periods may be based on a bioimpedance measured from EEG electrodes simultaneously with the EEG measurement or on EOG signal data measured from the subject.
摘要翻译：本发明涉及一种用于确定受试者睡眠深度的机制。为了以用户友好的方式获得关于睡眠深度的连续性的信息，而不需要高计算能力，从受试者获得EEG信号数据，检测对象的REM睡眠周期，并且指示导出EEG信号数据的不规则性。基于测量和检测到的REM睡眠周期，产生睡眠深度指数和状态信息，其中索引指示被摄体的睡眠深度，并且状态信息指示是否在期间获得EEG信号数据 REM睡眠期。 REM周期的检测可以基于与EEG测量同时测量的EEG电极的生物阻抗或从受试者测量的EOG信号数据。

2. 发明申请

US20140257286A1 Anatomically customized and mobilizing external support, method for manufacture 审中-公开
公开(公告)号：US20140257286A1
公开(公告)日：2014-09-11
申请号：US14285726
申请日：2014-05-23
申请人： Jan Erik Lindahl , Jari Salo , Jukka Tuomi , Roy Björkstrand , Markku Paloheimo
发明人： Jan Erik Lindahl , Jari Salo , Jukka Tuomi , Roy Björkstrand , Markku Paloheimo
IPC分类号： A61B17/62
CPC分类号： A61B17/62 , A61B5/103 , A61B5/1121 , A61B5/1124 , A61B5/4528 , A61B5/6878 , A61B17/6425 , B33Y80/00
摘要： The present invention relates to an anatomically personalized and mobilizing external support, a method for manufacturing is, as well as the use of a component of an invasively attached external support in determining the path of the joint being supported. In the method according to the invention, the kinetic dynamics of the joint are measured with the aid of a component of an external support invasively attached to two bone groups, on the basis of which an external support is arranged between the bone groups.

3. 发明申请

US20070015985A1 Method of positioning electrodes for central nervous system monitoring and sensing pain reactions of a patient 审中-公开
标题翻译：定位用于中枢神经系统监测和感测患者疼痛反应的电极的方法
公开(公告)号：US20070015985A1
公开(公告)日：2007-01-18
申请号：US11523997
申请日：2006-09-20
申请人： Heli Tolvanen-Laakso , Hanna Viertio-Oja , Markku Paloheimo
发明人： Heli Tolvanen-Laakso , Hanna Viertio-Oja , Markku Paloheimo
IPC分类号： A61B5/04 , A61B5/05
CPC分类号： A61B5/4821 , A61B5/0478 , A61B5/0492 , A61B5/1106 , A61B5/6814
摘要： A method concerning measurements by using an electrode array comprising three electrodes for central nervous system (CNS) monitoring from the forehead of a patient's head. A first electrode of said three electrodes is positioned between the eyebrows or immediately above the eyebrows of the patient. A third electrode of said three electrodes is positioned apart from the first electrode on the hairless fronto-lateral area of the forehead the patient. A second electrode is positioned between the first and the third electrodes on the forehead of the patient.
摘要翻译：一种关于通过使用包括从患者头部前额监测的中枢神经系统（CNS）的三个电极的电极阵列进行测量的方法。所述三个电极的第一电极位于眉毛之间或紧接在患者的眉毛之上。所述三个电极的第三电极在患者的额头的无毛正面 - 横向区域上与第一电极分开。第二电极位于患者前额上的第一和第三电极之间。

4. 发明授权

US07130673B2 Method of positioning electrodes for central nervous system monitoring and sensing pain reactions of a patient 有权
标题翻译：定位用于中枢神经系统监测和感测患者疼痛反应的电极的方法
公开(公告)号：US07130673B2
公开(公告)日：2006-10-31
申请号：US10409679
申请日：2003-04-08
申请人： Heli Tolvanen-Laakso , Hanna Viertiö-Oja , Markku Paloheimo
发明人： Heli Tolvanen-Laakso , Hanna Viertiö-Oja , Markku Paloheimo
IPC分类号： A61B5/0478 , A61B5/0492
CPC分类号： A61B5/4821 , A61B5/0478 , A61B5/0492 , A61B5/1106 , A61B5/6814
摘要： A method concerning measurements by using an electrode array comprising three electrodes for central nervous system (CNS) monitoring from the forehead of a patient's head. A first electrode of said three electrodes is positioned between the eyebrows or immediately above the eyebrows of the patient. A third electrode of said three electrodes is positioned apart from the first electrode on the hairless fronto-lateral area of the forehead the patient. A second electrode is positioned between the first and the third electrodes on the forehead of the patient.
摘要翻译：一种关于通过使用包括从患者头部前额监测的中枢神经系统（CNS）的三个电极的电极阵列进行测量的方法。所述三个电极的第一电极位于眉毛之间或紧接在患者的眉毛之上。所述三个电极的第三电极在患者的额头的无毛正面 - 横向区域上与第一电极分开。第二电极位于患者前额上的第一和第三电极之间。

5. 发明授权

US08463370B2 Method and apparatus based on combination of physiological parameters for assessment of analgesia during anesthesia or sedation 有权
标题翻译：基于麻醉或镇静镇痛评估的生理参数组合的方法和装置
公开(公告)号：US08463370B2
公开(公告)日：2013-06-11
申请号：US12052542
申请日：2008-03-20
申请人： Ilkka Korhonen , Marcus Johannis Van Gils , Markku Paloheimo , Arvi Yli-Hankala , Matti Veli Tapani Huiku
发明人： Ilkka Korhonen , Marcus Johannis Van Gils , Markku Paloheimo , Arvi Yli-Hankala , Matti Veli Tapani Huiku
IPC分类号： A61B5/04
CPC分类号： A61B5/4035 , A61B5/1106 , A61B5/412 , A61B5/4821 , A61B2505/05
摘要： The invention relates to a method for monitoring a condition of a patient under anesthesia or sedation, whereupon one, two, three or more signals are acquired, and the signal(s) represent(s) cardiovascular and/or combined electrical biopotential on skull activity of the patient. From said signal or signals are derived or calculated at least two parameter values related to a quantity like waveform amplitude, waveform periodicity, waveform morphology, waveform variability, energy, power, signal complexity and frequency content. A predetermined mathematical index for probability of patient comfort is used, in which function said parameters are variables, and successively changing probability index values of said mathematical index is calculated.
摘要翻译：本发明涉及用于监测麻醉或镇静患者状况的方法，因此获得一个，两个，三个或更多个信号，并且该信号代表颅骨活动的心血管和/或组合电生物电位的病人。从所述信号或信号中导出或计算出与诸如波形幅度，波形周期性，波形形态，波形变化性，能量，功率，信号复杂度和频率内容之类的量相关的至少两个参数值。使用患者舒适概率的预定数学指标，其中所述参数是变量，并且计算所述数学指标的连续变化的概率指标值。

6. 发明申请

US20050010116A1 Method and apparatus based on combination of physiological parameters for assessment of analgesia during anesthesia or sedation 有权
标题翻译：基于麻醉或镇静镇痛评估的生理参数组合的方法和装置
公开(公告)号：US20050010116A1
公开(公告)日：2005-01-13
申请号：US10614749
申请日：2003-07-07
申请人： Ilkka Korhonen , Marcus Johannis Gils , Markku Paloheimo , Arvi Yli-Hankala , Matti Huiku
发明人： Ilkka Korhonen , Marcus Johannis Gils , Markku Paloheimo , Arvi Yli-Hankala , Matti Huiku
IPC分类号： A61B5/11 , A61B5/02
CPC分类号： A61B5/4035 , A61B5/1106 , A61B5/412 , A61B5/4821 , A61B2505/05
摘要： The invention relates to a method for monitoring a condition of a patient under anesthesia or sedation, whereupon one, two, three or more signals are acquired, and the signal(s) represent(s) cardiovascular and/or combined electrical biopotential on skull activity of the patient. From said signal or signals are derived or calculated at least two parameter values related to a quantity like waveform amplitude, waveform periodicity, waveform morphology, waveform variability, energy, power, signal complexity and frequency content. A predetermined mathematical index for probability of patient comfort is used, in which function said parameters are variables, and successively changing probability index values of said mathematical index is calculated.
摘要翻译：本发明涉及用于监测麻醉或镇静患者状况的方法，因此获得一个，两个，三个或更多个信号，并且该信号代表颅骨活动的心血管和/或组合电生物电位的病人。从所述信号或信号中导出或计算出与诸如波形幅度，波形周期性，波形形态，波形变化性，能量，功率，信号复杂度和频率内容之类的量相关的至少两个参数值。使用患者舒适概率的预定数学指标，其中所述参数是变量，并且计算所述数学指标的连续变化的概率指标值。

7. 发明授权

US07367949B2 Method and apparatus based on combination of physiological parameters for assessment of analgesia during anesthesia or sedation 有权
标题翻译：基于麻醉或镇静镇痛评估的生理参数组合的方法和装置
公开(公告)号：US07367949B2
公开(公告)日：2008-05-06
申请号：US10614749
申请日：2003-07-07
申请人： Ilkka Korhonen , Marcus Johannis Van Gils , Markku Paloheimo , Arvi Yli-Hankala , Matti Veli Tapani Huiku
发明人： Ilkka Korhonen , Marcus Johannis Van Gils , Markku Paloheimo , Arvi Yli-Hankala , Matti Veli Tapani Huiku
IPC分类号： A61B5/02
CPC分类号： A61B5/4035 , A61B5/1106 , A61B5/412 , A61B5/4821 , A61B2505/05
摘要： The invention relates to a method for monitoring a condition of a patient under anesthesia or sedation, whereupon one, two, three or more signals are acquired, and the signal(s) represent(s) cardiovascular and/or combined electrical biopotential on skull activity of the patient. From said signal or signals are derived or calculated at least two parameter values related to a quantity like waveform amplitude, waveform periodicity, waveform morphology, waveform variability, energy, power, signal complexity and frequency content. A predetermined mathematical index for probability of patient comfort is used, in which function said parameters are variables, and successively changing probability index values of said mathematical index is calculated.
摘要翻译：本发明涉及用于监测麻醉或镇静患者状况的方法，因此获得一个，两个，三个或更多个信号，并且该信号代表颅骨活动的心血管和/或组合电生物电位的病人。从所述信号或信号中导出或计算出与诸如波形幅度，波形周期性，波形形态，波形变化性，能量，功率，信号复杂度和频率内容之类的量相关的至少两个参数值。使用患者舒适概率的预定数学指标，其中所述参数是变量，并且计算所述数学指标的连续变化的概率指标值。

8. 发明授权

US5722449A Arrangement in connection with a gas mixer 失效
标题翻译：与气体混合器相关的布置
公开(公告)号：US5722449A
公开(公告)日：1998-03-03
申请号：US868469
申请日：1997-06-03
申请人： Erkki Heinonen , Markku Paloheimo
发明人： Erkki Heinonen , Markku Paloheimo
IPC分类号： A61M16/12 , A61M16/10 , G05D11/13
CPC分类号： A61M16/12 , A61M2016/003 , Y10T137/2529 , Y10T137/2531
摘要： An arrangement in connection with a gas mixer, which is arranged to form a mixed gas of oxygen and another gas to be mixed with it. To provide a simple and reliable arrangement, before the mixed gas is formed the oxygen is arranged to be supplied through both a mechanical adjusting means, and a mechanical and electronic flow-measuring means. The other gas to be mixed with oxygen is arranged to flow through an electronic flow-measuring device. The flow of the other gas is arranged to be regulated by means of an electronically controlled regulating valve, whereupon the electronic flow-measuring means, the electronic flow-measuring device, and the electronically controlled regulating valve are arranged to be operated by means of a control unit.
摘要翻译：与气体混合器相关的布置，其布置成形成氧气和与其混合的另一种气体的混合气体。为了提供简单可靠的布置，在形成混合气体之前，将氧气布置成通过机械调节装置和机械和电子流量测量装置供应。与氧气混合的其他气体被布置成流过电子流量测量装置。其他气体的流动被布置成通过电子调节调节阀来调节，于是电子流量测量装置，电子流量测量装置和电子调节阀被设置成通过控制单元

9. 发明授权

US5482035A Method for monitoring the condition of a patient 失效
标题翻译：监测患者状况的方法
公开(公告)号：US5482035A
公开(公告)日：1996-01-09
申请号：US214641
申请日：1994-03-17
申请人： Markku Paloheimo
发明人： Markku Paloheimo
IPC分类号： A61B5/02 , A61B5/00
CPC分类号： A61B5/02
摘要： The invention relates to a method for anticipating a change occurring in the condition of a patient's organism before the condition of a patient reaches a critical point, the condition of a patient's organism being monitored by the application of an appropriate measuring method and the determinations according to said measuring method being effected at appropriate time intervals. The measuring results obtained on the basis of effected measurements, the number of which must be at least two, or quantities derived therefrom are utilized for predicting the future development of one or more measuring results and, if a measuring result according to the prediction indicates that a limit value representing a predetermined critical point is reached in the condition of a patient within a predetermined period of time, a warning signal is released indicating that this critical point is being approached.
摘要翻译：本发明涉及一种在患者病情达到临界点之前预测患者生物体状况发生变化的方法，通过适用的测量方法和根据本发明的测定方法监测患者生物体的状况所述测量方法以适当的时间间隔进行。基于实验测量获得的测量结果，其数量必须至少为2，或从其得到的量用于预测一个或多个测量结果的未来发展，并且如果根据预测的测量结果表明在预定时间段内患者的状况下达到表示预定临界点的极限值，释放指示该临界点正在接近的警告信号。

10. 发明申请

US20120277744A1 Anatomically customized and mobilizing external support, method for manufacture 有权
标题翻译：解剖定制和动员外部支持，制造方法
公开(公告)号：US20120277744A1
公开(公告)日：2012-11-01
申请号：US13499911
申请日：2010-09-30
申请人： Jan Erik Lindahl , Jari Salo , Jukka Tuomi , Roy Björkstrand , Markku Paloheimo , Kaija-Stlina Paloheimo
发明人： Jan Erik Lindahl , Jari Salo , Jukka Tuomi , Roy Björkstrand , Markku Paloheimo , Kaija-Stlina Paloheimo
IPC分类号： A61B17/62
CPC分类号： A61B17/62 , A61B5/103 , A61B5/1121 , A61B5/1124 , A61B5/4528 , A61B5/6878 , A61B17/6425 , B33Y80/00
摘要： The present invention relates to an anatomically personalized and mobilizing external support, a method for manufacturing is, as well as the use of a component of an invasively attached external support in determining the path of the joint being supported. In the method according to the invention, the kinetic dynamics of the joint are measured with the aid of a component of an external support invasively attached to two bone groups, on the basis of which an external support is arranged between the bone groups.
摘要翻译：本发明涉及一种解剖学上个性化和动员的外部支持，一种制造方法以及在确定被支撑的关节的路径中使用一种入侵附着的外部支撑件的部件。在根据本发明的方法中，借助于侵入性地附接到两个骨组的外部支撑的部件来测量关节的动力学动力学，在骨组之间布置有外部支撑。

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