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1. 发明申请

US20140005706A1 Carotid Body Ablation Via Directed Energy 有权
标题翻译：颈动脉身体通过定向能量消融
公开(公告)号：US20140005706A1
公开(公告)日：2014-01-02
申请号：US13933023
申请日：2013-07-01
申请人： Mark Gelfand , Charles Lennox , Ary Chernomorsky , Howard Levin , Veijo T. Suorsa , Kenneth M. Martin , Yegor D. Sinelnikov
发明人： Mark Gelfand , Charles Lennox , Ary Chernomorsky , Howard Levin , Veijo T. Suorsa , Kenneth M. Martin , Yegor D. Sinelnikov
IPC分类号： A61B17/32
CPC分类号： A61B18/1492 , A61B17/2202 , A61B17/320092 , A61B18/24 , A61B2017/00256 , A61B2017/003 , A61B2017/22024 , A61B2017/22028 , A61B2017/22058 , A61B2017/22062 , A61B2017/22069 , A61B2017/320044 , A61B2018/00404 , A61B2018/1425 , A61B2018/1475 , A61B2090/3784 , A61N7/022
摘要： Methods and devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation.
摘要翻译：用于评估和治疗患有交感神经介导的疾病的患者的方法和装置，通过减少化学传感器通过颈动脉体消融对输入神经系统的输入，涉及增加的外周化学反应和增强的交感神经紧张。

2. 发明申请

US20130324989A1 Percutaneous Methods and Devices for Carotid Body Ablation 有权
标题翻译：颈动脉身体消融的经皮方法和装置
公开(公告)号：US20130324989A1
公开(公告)日：2013-12-05
申请号：US13908995
申请日：2013-06-03
申请人： Mark Leung , Brett Schleicher , Charles Lennox , Ary Chernomorsky , Zoar Jacob Engelman , Marat Fudim , Martin M. Grasse , Mark Gelfand , Howard Levin
发明人： Mark Leung , Brett Schleicher , Charles Lennox , Ary Chernomorsky , Zoar Jacob Engelman , Marat Fudim , Martin M. Grasse , Mark Gelfand , Howard Levin
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B8/0841 , A61B8/0891 , A61B8/12 , A61B8/145 , A61B8/4227 , A61B8/488 , A61B18/1477 , A61B18/22 , A61B90/11 , A61B2018/00041 , A61B2018/00404 , A61B2018/00791 , A61B2018/0212 , A61B2018/0293 , A61B2090/376 , A61B2090/3762 , A61B2090/378 , A61N7/022 , A61N2007/0026 , F04C2270/0421
摘要： Methods and percutaneous devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via percutaneous carotid body ablation.
摘要翻译：用于评估和治疗患有交感神经介导的疾病的患者的方法和经皮装置，通过经由经皮颈动脉体消融将化学传感器输入减少到神经系统，涉及增加的外周化学反应和增强的交感神经紧张。

3. 发明申请

US20130324987A1 Methods and Devices for Cryogenic Carotid Body Ablation 有权
标题翻译：低温颈动脉身体消融的方法和装置
公开(公告)号：US20130324987A1
公开(公告)日：2013-12-05
申请号：US13908853
申请日：2013-06-03
申请人： Mark Leung , Eric Ryba , Charles Lennox , Ary Chernomorsky , Zoar Jacob Engelman , Marat Fudim , Martin M. Grasse , Mark Gelfand , Howard Levin , Brett Schleicher
发明人： Mark Leung , Eric Ryba , Charles Lennox , Ary Chernomorsky , Zoar Jacob Engelman , Marat Fudim , Martin M. Grasse , Mark Gelfand , Howard Levin , Brett Schleicher
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B18/0218 , A61B18/1492 , A61B2018/00041 , A61B2018/0022 , A61B2018/00285 , A61B2018/00291 , A61B2018/00345 , A61B2018/00404 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262 , A61B2018/0293 , A61B2090/376 , A61B2090/3762 , A61B2090/378 , A61B2090/3782
摘要： Methods and cryogenic devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation.
摘要翻译：用于评估和治疗患有交感神经介导的疾病的患者的方法和低温装置涉及增加的外周化学反应和增强的交感神经紧张，通过减少化学传感器通过颈动脉体消融输入神经系统。

4. 发明申请

US20060135912A1 Biodegradable pericardia constraint system and method 审中-公开
标题翻译：可生物降解的心包约束系统及方法
公开(公告)号：US20060135912A1
公开(公告)日：2006-06-22
申请号：US11282694
申请日：2005-11-21
申请人： Ary Chernomorsky , Mark Gelfand , Howard Levin
发明人： Ary Chernomorsky , Mark Gelfand , Howard Levin
IPC分类号： A61M1/00
CPC分类号： A61M25/0084 , A61B17/00491 , A61B2017/00247 , A61B2018/00392
摘要： A system has been developed for injecting a biodegradable pericardial constraint including: a biodegradable viscoelastic substance (BES); an external injection container for the BES; a cannula having a distal section adapted to be inserted into a pericardial sac of a mammalian heart and a proximal section connectable to the external injection container; wherein BES from the injection container is injected into the pericardial sac through the cannula.
摘要翻译：已经开发了用于注射可生物降解的心包约束的系统，包括：生物可降解粘弹性物质（BES）; 用于BES的外部注射容器; 套管，其具有适于插入哺乳动物心脏的心包囊中的远端部分和可连接到外部注射容器的近端部分; 其中来自注射容器的BES通过套管被注射到心包囊中。

5. 发明申请

US20060229492A1 MATERIALS AND METHODS FOR IN SITU FORMATION OF A HEART CONSTRAINER 审中-公开
标题翻译：用于形成心脏约束器的材料和方法
公开(公告)号：US20060229492A1
公开(公告)日：2006-10-12
申请号：US11279026
申请日：2006-04-07
申请人： Mark Gelfand , Howard Levin , Ary Chernomorsky
发明人： Mark Gelfand , Howard Levin , Ary Chernomorsky
IPC分类号： A61F2/00
CPC分类号： A61L31/04 , A61F2002/249 , A61L31/14 , A61L2400/06 , A61L2430/20
摘要： A method to constrain a heart including the steps of: injecting a biopolymer into a pericardial space of the heart; inducing intramolecular or intermolecular interactions in the biopolymer in the pericardial space to modify physical properties of the biopolymer in the pericardial space, and constraining the heart with the modified biopolymer in the pericardial space.
摘要翻译：一种限制心脏的方法，包括以下步骤：将生物聚合物注射到心脏的心包空间中; 诱导心包空间中的生物聚合物中的分子内或分子间相互作用，以改变心包空间中的生物聚合物的物理性质，并用心包空间中的改性生物聚合物约束心脏。

6. 发明申请

US20070198010A1 Methods and systems for in situ tissue marking and orientation stabilization 审中-公开
标题翻译：用于原位组织标记和取向稳定的方法和系统
公开(公告)号：US20070198010A1
公开(公告)日：2007-08-23
申请号：US11737382
申请日：2007-04-19
申请人： Roberta LEE , James Vetter , Ary Chernomorsky
发明人： Roberta LEE , James Vetter , Ary Chernomorsky
IPC分类号： A61B18/00 , A61B10/00
CPC分类号： A61B10/0266 , A61B18/148 , A61B2018/00333 , A61B2018/00601 , A61B2018/141 , A61B2018/1475 , A61B2090/3908 , A61B2090/3937 , A61B2090/395
摘要： A method of marking an orientation of a cut specimen of tissue prior to excision thereof from a body includes steps of disposing a tissue-marking probe in the body adjacent the cut specimen, the tissue-marking probe including a tissue-marking tool configured to selectively mark the cut specimen. A surface of the cut specimen is then marked with the tissue-marking tool such that the orientation of the cut specimen within the body is discernable after the cut specimen is excised from the body. The tissue-marking tool may be configured to selectively bow out of and back into a window defined near a distal tip of the probe and the marking step may include a step of selectively bowing the tissue-marking tool out of the window and following the surface of the cut specimen while rotating the probe. The tissue-marking tool may include an RF cutting tool and the marking step may include a step of coagulating or cauterizing a selected portion of the surface of the cut specimen with the RF cutting tool. Alternatively, the marking step may include a step of delivering dye onto selected portions of the surface of the cut specimen.
摘要翻译：在从身体切除之前标记组织切割样本的取向的方法包括以下步骤：将组织标记探针设置在与切割的样本相邻的身体中，组织标记探针包括组织标记工具，其被配置为选择性地标记切割标本。然后用组织标记工具标记切割的样品的表面，使得在切割的样品从身体切除之后，切割的样品在体内的取向是可辨别的。组织标记工具可以被配置为选择性地弯曲到限定在探针的远侧末端附近的窗口中，并且标记步骤可以包括将组织标记工具选择性地弯曲出窗户并且跟随表面的步骤同时旋转探头。组织标记工具可以包括RF切割工具，并且标记步骤可以包括用RF切割工具凝固或烧灼切割样品表面的选定部分的步骤。或者，标记步骤可以包括将染料递送到切割样品的表面的选定部分上的步骤。

7. 发明申请

US20050020899A1 Post-biopsy cavity treatmetn implants and methods 审中-公开
标题翻译：活检后治疗植入物和方法
公开(公告)号：US20050020899A1
公开(公告)日：2005-01-27
申请号：US10627960
申请日：2003-07-25
申请人： Ary Chernomorsky , James Vetter , Simon Chernomorsky
发明人： Ary Chernomorsky , James Vetter , Simon Chernomorsky
IPC分类号： A61B19/00 , A61K49/04 , A61B5/05
CPC分类号： A61M31/005 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3987 , A61K49/04 , A61L31/146 , A61L31/18
摘要： An embodiment of a post-biopsy cavity treatment implant includes a first portion including a first porous matrix defining a first controlled pore architecture or crosslinking density, and a second portion coupled to the first portion. The second portion includes a second porous matrix that defines a second controlled pore architecture or a second crosslinking density that is different from the first controlled pore architecture or the first crosslinking density, causing the second portion to swell in a different manner than the first portion when the implant is placed in an aqueous environment.
摘要翻译：活检后腔腔治疗植入物的实施方案包括第一部分，其包括限定第一受控孔结构或交联密度的第一多孔基质，以及耦合到第一部分的第二部分。第二部分包括限定第二受控孔结构的第二多孔基质或不同于第一受控孔结构或第一交联密度的第二交联密度，导致第二部分以与第一部分不同的方式膨胀，将植入物置于含水环境中。

8. 发明申请

US20070203513A1 Methods and devices for cutting and collecting soft tissue 失效
标题翻译：切割和收集软组织的方法和装置
公开(公告)号：US20070203513A1
公开(公告)日：2007-08-30
申请号：US11742391
申请日：2007-04-30
申请人： James VETTER , Ary Chernomorsky , Mark Clifford , Dan Brounstein , Scott Anderson
发明人： James VETTER , Ary Chernomorsky , Mark Clifford , Dan Brounstein , Scott Anderson
IPC分类号： A61B17/32
CPC分类号： A61B10/0266 , A61B2017/00287 , A61B2017/008 , A61B2018/1407
摘要： A method of cutting breast tissue for removal may include a step of providing a tissue cutting device having an elongate cutting element, the cutting element being movable between a bowed position and a retracted position, the cutting element having a radially outer side and a radially inner side. The tissue cutting device may be introduced into a breast and the elongate cutting element may be moved to the bowed position. A power source may be coupled to the elongate cutting element; and the cutting element may be rotated after the moving step so that the cutting element cuts the breast tissue. The radially outer side of the cutting element may have a larger surface area for transmitting energy to cut the tissue than the radially inner side.
摘要翻译：切割乳房组织以便去除的方法可以包括提供具有细长切割元件的组织切割装置的步骤，所述切割元件可在弓形位置和缩回位置之间移动，所述切割元件具有径向外侧和径向内部侧。组织切割装置可以被引入到乳房中，并且细长切割元件可以移动到弓形位置。电源可以耦合到细长切割元件; 并且切割元件可以在移动步骤之后旋转，使得切割元件切割乳房组织。切割元件的径向外侧可以具有比径向内侧更大的用于传递切割组织的能量的表面积。

9. 发明申请

US20070135711A1 Methods and systems for marking post biopsy cavity sites 失效
标题翻译：用于标记活检后腔位点的方法和系统
公开(公告)号：US20070135711A1
公开(公告)日：2007-06-14
申请号：US11673510
申请日：2007-02-09
申请人： Ary Chernomorsky , Sean Daniel , James Vetter
发明人： Ary Chernomorsky , Sean Daniel , James Vetter
IPC分类号： A61B6/00
CPC分类号： A61B90/39 , A61B2090/3908 , A61B2090/3925
摘要： A method of marking a cavity in a breast for subsequent visualization may include steps of providing a device having a delivery opening, a first marker and a second marker, the first and second markers being movable through the delivery opening, the first marker being configured to be visualized by ultrasound and the second marker configured to be radiopaque, the first and second markers being free to move relative to one another; introducing the device into a breast so that the delivery opening is positioned in a cavity formed in the breast; and moving the first marker and the second marker through the delivery opening and into the cavity in the breast, the first and second markers being free to move relative to one another when delivered into the cavity so that the first and second markers may take a number of different positions relative to one another when positioned within the cavity.
摘要翻译：一种在乳房中标记腔体以便随后可视化的方法可以包括提供具有输送开口，第一标记和第二标记的装置的步骤，第一和第二标记可移动穿过输送开口，第一标记被配置为通过超声可视化，第二标记被配置为不透射线，第一和第二标记物可相对于彼此自由移动; 将装置引入乳房，使得输送口位于形成在乳房中的空腔中; 以及通过所述输送开口移动所述第一标记和所述第二标记并进入所述乳房中的空腔中，所述第一标记和所述第二标记在递送到所述空腔中时相对于彼此自由移动，使得所述第一标记和所述第二标记可以取数当位于空腔内时相对于彼此的不同位置。

10. 发明申请

US20060229650A1 Methods and devices for cutting and collecting soft tissue 审中-公开
标题翻译：切割和收集软组织的方法和装置
公开(公告)号：US20060229650A1
公开(公告)日：2006-10-12
申请号：US11391791
申请日：2006-03-28
申请人： James Vetter , Ary Chernomorsky , Mark Clifford , Dan Brounstein , Scott Anderson
发明人： James Vetter , Ary Chernomorsky , Mark Clifford , Dan Brounstein , Scott Anderson
IPC分类号： A61B17/32
CPC分类号： A61B10/0266 , A61B2017/00287 , A61B2017/008 , A61B2018/1407
摘要： Devices and methods for cutting and collecting a specimen from a mass of tissue. The device may include an integrated cut and collect assembly. The integrated cut and collect assembly includes a cutting portion and a collection portion that includes a flexible membrane. The collection portion of the assembly is attached to the cutting portion thereof. The cutting portion is configured to cut the specimen from the mass of tissue and the collection portion is configured to collect the cut specimen and to encapsulate and isolate the cut specimen within the membrane to enable its safe retraction from the mass of tissue.
摘要翻译：从大量组织切割和收集标本的装置和方法。该装置可以包括集成的切割和收集组件。集成的切割和收集组件包括切割部分和包括柔性膜的收集部分。组件的收集部分附接到其切割部分。切割部分被构造成从组织块切割样本，并且收集部分被配置为收集切割的样本并且将切割的样本包封并分离在膜内以使其能够从组织块的安全回缩。

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