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    • 3. 发明授权
    • Methods and compositions for the treatment of gastrointestinal disorders
    • 用于治疗胃肠道疾病的方法和组合物
    • US07704947B2
    • 2010-04-27
    • US11930696
    • 2007-10-31
    • Mark G. CurrieShalina Mahajan-MiklosThea NormanG. Todd Milne
    • Mark G. CurrieShalina Mahajan-MiklosThea NormanG. Todd Milne
    • C07K7/08
    • C07K7/08A61K38/00C07K14/245
    • The present invention features compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), Crohn's disease, ulcerative colitis, Inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
    • 本发明的特征在于用于治疗IBS和其他胃肠道疾病和病症(例如胃肠蠕动障碍,功能性胃肠道疾病,胃食管反流病(GERD),克罗恩病,溃疡性结肠炎,炎性肠病,功能性胃灼热,消化不良( 包括功能性消化不良或非溃疡性消化不良),胃轻瘫,慢性肠假性梗阻(或结肠假性梗阻)以及与便秘相关的疾病和病症,例如与使用阿片类止痛药相关的便秘,手术后便秘和便秘​​相关 与使用活化鸟苷酸环化酶C(GC-C)受体的肽和其他试剂的神经性疾病以及其它病症和病症。
    • 5. 发明授权
    • Methods and compositions for the treatment of gastrointestinal disorders
    • 用于治疗胃肠道疾病的方法和组合物
    • US08110553B2
    • 2012-02-07
    • US12788979
    • 2010-05-27
    • Mark G. CurrieShalina Mahajan-MiklosG. Todd MilneThea Norman
    • Mark G. CurrieShalina Mahajan-MiklosG. Todd MilneThea Norman
    • A61K38/10
    • C07K7/08C07K14/245
    • The present invention features compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), Crohn's disease, ulcerative colitis, Inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation (post-operative ileus), and constipation associated with neuropathic disorders as well as other conditions and disorders using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
    • 本发明的特征在于用于治疗IBS和其他胃肠道疾病和病症(例如胃肠蠕动障碍,功能性胃肠道疾病,胃食管反流病(GERD),克罗恩病,溃疡性结肠炎,炎性肠病,功能性胃灼热,消化不良( 包括功能性消化不良或非溃疡性消化不良),胃轻瘫,慢性肠假性梗阻(或结肠假性梗阻)以及与便秘相关的疾病和病症,例如与使用阿片类止痛药相关的便秘,手术后便秘 肠梗阻)和与神经性疾病相关的便秘以及使用活化鸟苷酸环化酶C(GC-C)受体的肽和其它试剂的其他病症和病症。
    • 9. 发明授权
    • Methods and compositions for the treatment of gastrointestinal disorders
    • 用于治疗胃肠道疾病的方法和组合物
    • US07745409B2
    • 2010-06-29
    • US11949340
    • 2007-12-03
    • Mark G. CurrieShalina Mahajan-MiklosThea NormanG. Todd Milne
    • Mark G. CurrieShalina Mahajan-MiklosThea NormanG. Todd Milne
    • A61K38/00
    • C07K7/08C07K14/245
    • The present invention features compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), Crohn's disease, ulcerative colitis, Inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation (post-operative ileus), and constipation associated with neuropathic disorders as well as other conditions and disorders using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
    • 本发明的特征在于用于治疗IBS和其他胃肠道疾病和病症(例如胃肠蠕动障碍,功能性胃肠道疾病,胃食管反流病(GERD),克罗恩病,溃疡性结肠炎,炎性肠病,功能性胃灼热,消化不良( 包括功能性消化不良或非溃疡性消化不良),胃轻瘫,慢性肠假性梗阻(或结肠假性梗阻)以及与便秘相关的疾病和病症,例如与使用阿片类止痛药相关的便秘,手术后便秘 肠梗阻)和与神经性疾病相关的便秘以及使用活化鸟苷酸环化酶C(GC-C)受体的肽和其它试剂的其他病症和病症。