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    • 1. 发明专利
    • Sistema para inducir efectos de temperatura deseables sobre un tejido corporal
    • ES2407329T3
    • 2013-06-12
    • ES07844424
    • 2007-10-18
    • MINNOW MEDICAL INCVESSIX VASCULAR INC
    • STONE CORBETTHOEY MICHAELBLANCK ARTHURBRIGGS LENPERRY MIKEGUSTUS ROLFE
    • A61B18/14
    • Un sistema para inducir efectos de temperatura deseables sobre un tejido corporal, estando dispuesto el tejidocorporal alrededor de un lumen, sistema que comprende: un cuerpo (14) de catéter que tiene un extremo proximal y un extremo distal con un eje entre ellos;un miembro que se puede expandir radialmente y que comprende un balón (20) inflable alargado soportado porel extremo distal del cuerpo (14) de catéter, en el que el balón (20) tiene una configuración de inserción de perfilbajo y una configuración de perfil mayor; y una pluralidad de electrodos (34) montados o hechos sobre sustratos flexibles o circuitos flexibles (35) fijados albalón (20) con un adhesivo adecuado, en el que cada circuito flexible se extiende a lo largo del eje del balón ylos circuitos flexibles están separados circunferencialmente alrededor del balón (20), cada circuito flexible tieneal menos un par de electrodos (34) bipolar y el balón (20) tiene una pluralidad de pliegues para facilitar elcambio entre la configuración de perfil bajo y la configuración de perfil mayor con los pliegues dispuestos entrelos electrodos (34), de forma que los pares de electrodos bipolares definen zonas de remodelado en el tejidocuando el balón (20) está en la configuración de perfil mayor en el interior del lumen, los electrodos (34) estánacoplados radialmente con el tejido y energía para remodelado del tejido es transmitida entre los electrodos y eltejido para calentar el tejido dentro de las zonas de remodelado.
    • 3. 发明专利
    • System for inducing desirable temperature effects on body tissue
    • AU2013231125B2
    • 2015-08-20
    • AU2013231125
    • 2013-09-20
    • VESSIX VASCULAR INC
    • BLANCK ARTHUR GSTONE CORBETT WGUSTUS ROLFE TYSONHOEY MICHAEL FPERRY MIKEBRIGGS LEN
    • A61B18/04A61B18/14
    • SYSTEM FOR INDUCING DESIRABLE TEMPERATURE EFFECTS ON BODY TISSUE There is disclosed herein a system for inducing desirable temperature effects on a target body tissue disposed about a blood vessel, the system comprising: a catheter body having a proximal end and a distal end with an axis therebetween; a radially expandable member supported by the distal end of the catheter body, the expandable member having a low profile insertion configuration and a larger profile configuration; and a plurality of electrodes included on a plurality of separate flexible circuits each attached to an outer surface of the expandable member so as to radially couple with a wall of the blood vessel and define a plurality of remodeling zones in a tissue treatment area when the expandable member is in the large profile configuration within the blood vessel, wherein the plurality of electrodes are distributed circumferentially about the balloon such that the plurality of remodeling zones extend about the circumference of the blood vessel, wherein each of the plurality of flexible circuits includes a polymeric substrate supporting at least one pair of electrodes; wherein the plurality of electrodes are configured to transmit a tissue remodeling energy to each of the plurality of remodeling zones such that when at least some remodeling zones of the plurality include collateral tissue without the target body tissue, the tissue remodeling energy is transmitted to the at least some remodeling zones heating the collateral tissue without causing thermal damage, while the tissue remodeling energy transmitted to remodeling zones including both the target tissue and collateral tissue heats the target tissue sufficiently to efficaciously alter the target tissue without causing thermal damage to the collateral healthy tissue.
    • 4. 发明专利
    • System for inducing desirable temperature effects on body tissue
    • AU2013231125A1
    • 2013-10-10
    • AU2013231125
    • 2013-09-20
    • VESSIX VASCULAR INC
    • BLANCK ARTHUR GSTONE CORBETT WGUSTUS ROLFE TYSONHOEY MICHAEL FPERRY MIKEBRIGGS LEN
    • A61B18/04A61B18/14
    • SYSTEM FOR INDUCING DESIRABLE TEMPERATURE EFFECTS ON BODY TISSUE There is disclosed herein a system for inducing desirable temperature effects on a target body tissue disposed about a blood vessel, the system comprising: a catheter body having a proximal end and a distal end with an axis therebetween; a radially expandable member supported by the distal end of the catheter body, the expandable member having a low profile insertion configuration and a larger profile configuration; and a plurality of electrodes included on a plurality of separate flexible circuits each attached to an outer surface of the expandable member so as to radially couple with a wall of the blood vessel and define a plurality of remodeling zones in a tissue treatment area when the expandable member is in the large profile configuration within the blood vessel, wherein the plurality of electrodes are distributed circumferentially about the balloon such that the plurality of remodeling zones extend about the circumference of the blood vessel, wherein each of the plurality of flexible circuits includes a polymeric substrate supporting at least one pair of electrodes; wherein the plurality of electrodes are configured to transmit a tissue remodeling energy to each of the plurality of remodeling zones such that when at least some remodeling zones of the plurality include collateral tissue without the target body tissue, the tissue remodeling energy is transmitted to the at least some remodeling zones heating the collateral tissue without causing thermal damage, while the tissue remodeling energy transmitted to remodeling zones including both the target tissue and collateral tissue heats the target tissue sufficiently to efficaciously alter the target tissue without causing thermal damage to the collateral healthy tissue.