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1. 发明专利

AU2013237732B2 Inducing desirable temperature effects on body tissue 未知
公开(公告)号：AU2013237732B2
公开(公告)日：2015-10-22
申请号：AU2013237732
申请日：2013-10-04
申请人： VESSIX VASCULAR INC
发明人： BLANCK ARTHUR G , STONE CORBETT W , GUSTUS ROLFE TYSON , HOEY MICHAEL F , PERRY MIKE , KUNSTMANAS LINAS R
IPC分类号： A61B18/14
摘要： INDUCING DESIRABLE TEMPERATURE EFFECTS ON BODY TISSUE There is disclosed a system (10) for remodeling tissue disposed about a blood vessel, the system comprising: an endovascular catheter (12) having an energy delivery portion, the energy delivery portion having a plurality of energy delivery regions, wherein the energy delivery portion comprises a plurality of electrodes (34) mounted on a surface of a balloon (20) of the catheter and arranged in an array so as to define a plurality of remodeling zones in the tissue when the balloon is in contact with a wall of the blood vessel; and an energy source (42) coupleable with the catheter, the energy source configured to deliver controlled quantities of energy to the energy delivery portion thereby transmitting desired quantities of tissue remodeling energy to each of the energy delivery regions in response to an input such that the energy is suitable for heating a plurality of remodeling zones of the tissue, wherein the energy source is configured to deliver bipolar tissue remodeling energy with bipolar electrode pairs of the plurality of electrodes so as to heat each of the plurality of remodeling zones, and wherein the energy source is configured to delivery energy with the electrodes by energizing the electrode pairs with 0.5 to 5 Watts for 0.1 to 180 seconds.

2. 发明专利

ES2560006T3 Inducción de efectos de temperatura deseables sobre tejido corporal 未知
公开(公告)号：ES2560006T3
公开(公告)日：2016-02-17
申请号：ES12154120
申请日：2007-10-18
申请人： VESSIX VASCULAR INC
发明人： STONE CORBETT W , HOEY MICHAEL F , GUSTUS ROLFE TYSON , PERRY MIKE , BLANCK ARTHUR G , KUNSTMANAS LINAS R
IPC分类号： A61B18/14
摘要： Un sistema para tratar tejido dispuesto alrededor de un vaso sanguíneo, comprendiendo el sistema: un catéter endovascular que tiene una parte de suministro de energía, teniendo la parte de suministro de energía una pluralidad de pares de electrodos bipolares montados sobre una superficie externa de un balón del catéter y dispuestos en una disposición ordenada; y una fuente de energía acoplable con el catéter, estando la fuente de energía configurada para suministrar cantidades controladas de energía a cada uno de los pares de electrodos bipolares en respuesta a una entrada, y en el que la fuente de energía está configurada para excitar los pares de electrodos con de 0,25 a 5 vatios de potencia promedio durante de 1 a 180 segundos.

3. 发明专利

AU2013231125B2 System for inducing desirable temperature effects on body tissue 未知
公开(公告)号：AU2013231125B2
公开(公告)日：2015-08-20
申请号：AU2013231125
申请日：2013-09-20
申请人： VESSIX VASCULAR INC
发明人： BLANCK ARTHUR G , STONE CORBETT W , GUSTUS ROLFE TYSON , HOEY MICHAEL F , PERRY MIKE , BRIGGS LEN
IPC分类号： A61B18/04 , A61B18/14
摘要： SYSTEM FOR INDUCING DESIRABLE TEMPERATURE EFFECTS ON BODY TISSUE There is disclosed herein a system for inducing desirable temperature effects on a target body tissue disposed about a blood vessel, the system comprising: a catheter body having a proximal end and a distal end with an axis therebetween; a radially expandable member supported by the distal end of the catheter body, the expandable member having a low profile insertion configuration and a larger profile configuration; and a plurality of electrodes included on a plurality of separate flexible circuits each attached to an outer surface of the expandable member so as to radially couple with a wall of the blood vessel and define a plurality of remodeling zones in a tissue treatment area when the expandable member is in the large profile configuration within the blood vessel, wherein the plurality of electrodes are distributed circumferentially about the balloon such that the plurality of remodeling zones extend about the circumference of the blood vessel, wherein each of the plurality of flexible circuits includes a polymeric substrate supporting at least one pair of electrodes; wherein the plurality of electrodes are configured to transmit a tissue remodeling energy to each of the plurality of remodeling zones such that when at least some remodeling zones of the plurality include collateral tissue without the target body tissue, the tissue remodeling energy is transmitted to the at least some remodeling zones heating the collateral tissue without causing thermal damage, while the tissue remodeling energy transmitted to remodeling zones including both the target tissue and collateral tissue heats the target tissue sufficiently to efficaciously alter the target tissue without causing thermal damage to the collateral healthy tissue.

4. 发明专利

AU2013231125A1 System for inducing desirable temperature effects on body tissue 未知
公开(公告)号：AU2013231125A1
公开(公告)日：2013-10-10
申请号：AU2013231125
申请日：2013-09-20
申请人： VESSIX VASCULAR INC
发明人： BLANCK ARTHUR G , STONE CORBETT W , GUSTUS ROLFE TYSON , HOEY MICHAEL F , PERRY MIKE , BRIGGS LEN
IPC分类号： A61B18/04 , A61B18/14
摘要： SYSTEM FOR INDUCING DESIRABLE TEMPERATURE EFFECTS ON BODY TISSUE There is disclosed herein a system for inducing desirable temperature effects on a target body tissue disposed about a blood vessel, the system comprising: a catheter body having a proximal end and a distal end with an axis therebetween; a radially expandable member supported by the distal end of the catheter body, the expandable member having a low profile insertion configuration and a larger profile configuration; and a plurality of electrodes included on a plurality of separate flexible circuits each attached to an outer surface of the expandable member so as to radially couple with a wall of the blood vessel and define a plurality of remodeling zones in a tissue treatment area when the expandable member is in the large profile configuration within the blood vessel, wherein the plurality of electrodes are distributed circumferentially about the balloon such that the plurality of remodeling zones extend about the circumference of the blood vessel, wherein each of the plurality of flexible circuits includes a polymeric substrate supporting at least one pair of electrodes; wherein the plurality of electrodes are configured to transmit a tissue remodeling energy to each of the plurality of remodeling zones such that when at least some remodeling zones of the plurality include collateral tissue without the target body tissue, the tissue remodeling energy is transmitted to the at least some remodeling zones heating the collateral tissue without causing thermal damage, while the tissue remodeling energy transmitted to remodeling zones including both the target tissue and collateral tissue heats the target tissue sufficiently to efficaciously alter the target tissue without causing thermal damage to the collateral healthy tissue.

5. 发明专利

AU2016201555A1 Selective accumulation of energy with or without knowledge of tissue topography 未知
公开(公告)号：AU2016201555A1
公开(公告)日：2016-03-31
申请号：AU2016201555
申请日：2016-03-10
申请人： VESSIX VASCULAR INC
发明人： GUSTUS ROLFE TYSON , KUNSTMANAS LINAS , BLANCK ARTHUR G
IPC分类号： A61B18/14
摘要： SELECTIVE ACCUMULATION OF ENERGY WITH OR WITHOUT KNOWLEDGE OF TISSUE TOPOGRAPHY Methods and systems for heating a body tissue region adjacent a body lumen with diseased and healthy portions using selective accumulation of energy in the artery tissue with or without knowledge of tissue topography. The method includes positioning an energy delivery portion of a catheter body within the lumen adjacent the body tissue region to be heated, determining a pulse characteristic in response to a thermal property of a first tissue type and applying pulsed energy with the pulse characteristic from the energy delivery portion so as to therapeutically treat the second tissue type within the body tissue region by drawing heat from the first tissue type at a rate that avoids significant thermal damage to the first tissue type while building-up heat in the second tissue type. 11091292_1

6. 发明专利

AU2009314133B2 Selective accumulation of energy with or without knowledge of tissue topography 未知
公开(公告)号：AU2009314133B2
公开(公告)日：2015-12-10
申请号：AU2009314133
申请日：2009-11-11
申请人： VESSIX VASCULAR INC
发明人： GUSTUS ROLFE TYSON , KUNSTMANAS LINAS , BLANCK ARTHUR G
IPC分类号： A61B18/14
摘要： Methods and systems for heating a body tissue region adjacent a body lumen with diseased and healthy portions using selective accumulation of energy in the artery tissue with or without knowledge of tissue topography. The method Includes positioning an energy delivery portion of a catheter body within the lumen adjacent the body tissue region to be heated, determining a pulse characteristic in response to a thermal property of a first tissue type and applying pulsed energy with the pulse characteristic from the energy delivery portion so as to therapeutically treat the second tissue type within the body tissue region by drawing heat from the first tissue type at a rate that avoids significant thermal damage to the first tissue type while building-up heat in the second tissue type.

7. 发明专利

AU2009313873B2 Selective drug delivery in a lumen 未知
公开(公告)号：AU2009313873B2
公开(公告)日：2015-03-12
申请号：AU2009313873
申请日：2009-11-13
申请人： VESSIX VASCULAR INC
发明人： PERRY MIKE , STONE CORBETT W , GUSTUS ROLFE TYSON , SCHREIBER RONDA , MAZOR MEITAL , CONN BRIAN
IPC分类号： A61F2/958 , A61M31/00
摘要： Methods and systems are disclosed for selective drug or fluid delivery in a lumen through a coating or fluid delivery channels. One system includes an elongate catheter having a proximal end and a distal end with an axis therebetween, the catheter having a radially expandable balloon near the distal end and an energy delivery portion proximate the balloon for transmission of energy, a thermally changeable coating having a releasable drug coupled to the balloon, the thermally changeable coating being oriented to be urged against the body tissue when the expandable balloon expands and an energy source operatively coupled to the energy delivery portion configured to energize the energy delivery portion to heat and liquefy the thermally changeable coating to release the drug to the body tissue.

8. 发明专利

AU2009292987A1 Inducing desirable temperature effects on body tissue using alternate energy sources 未知
公开(公告)号：AU2009292987A1
公开(公告)日：2010-03-25
申请号：AU2009292987
申请日：2009-09-21
申请人： VESSIX VASCULAR INC
发明人： GUSTUS ROLFE TYSON , STONE CORBETT W , HOEY MICHAEL F , BLANCK ARTHUR G , BRIGGS LEN , PERRY MIKE , MAZOR MEITAL , KUNSTMANAS LINAS R
IPC分类号： A61B17/00
摘要： A system for inducing desirable temperature effects on body tissue, the body tissue being disposed about a lumen. The system includes an elongate catheter having a proximal end and a distal end with an axis therebetween with an energy delivery portion for transmission of energy. A tissue analyzer configured to characterize the body tissue in the lumen proximate the energy delivery portion and an energy source coupled to the energy delivery portion transmitting tissue treatment energy, wherein the energy is non-RF energy. A processor coupled to the tissue analyzer and energy source, the processor configured to determine an appropriate treatment energy for the characterized body tissue so as to mildly heat the body tissue with the energy delivery portion without ablating.

9. 发明公开

EP2355737A4 SELECTIVE ACCUMULATION OF ENERGY WITH OR WITHOUT KNOWLEDGE OF TISSUE TOPOGRAPHY 有权转让
标题翻译：通过或者不通过组织形貌信息能量的选择性积累
公开(公告)号：EP2355737A4
公开(公告)日：2013-01-16
申请号：EP09826671
申请日：2009-11-11
申请人： VESSIX VASCULAR INC
发明人： GUSTUS ROLFE TYSON , KUNSTMANAS LINAS , BLANCK ARTHUR G
IPC分类号： A61B18/14 , A61N7/02
CPC分类号： A61F7/123 , A61B17/22004 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B2017/00022 , A61B2018/00023 , A61B2018/00214 , A61B2018/0022 , A61B2018/00422 , A61B2018/00791 , A61N7/022

10. 发明公开

EP2341839A4 INDUCING DESIRABLE TEMPERATURE EFFECTS ON BODY TISSUE USING ALTERNATE ENERGY SOURCES 有权
标题翻译： RELEASE WANT CHEAPER温度效应对身体组织基于替代能源
公开(公告)号：EP2341839A4
公开(公告)日：2012-11-14
申请号：EP09815350
申请日：2009-09-21
申请人： VESSIX VASCULAR INC
发明人： GUSTUS ROLFE TYSON , STONE CORBETT W , HOEY MICHAEL F , BLANCK ARTHUR G , BRIGGS LEN , PERRY MIKE , MAZOR MEITAL , KUNSTMANAS LINAS R
IPC分类号： A61B17/00
CPC分类号： A61B18/245 , A61B5/0066 , A61B5/0084 , A61B5/0088 , A61B5/055 , A61B8/12 , A61B17/2202 , A61B18/18 , A61B2017/00057 , A61B2018/00642 , A61B2018/2272 , A61B2090/374 , A61N7/022 , A61N2007/0078

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