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1. 发明申请

WO2005112569A3 METHODS FOR COMPOUNDING AND DELIVERING A THERAPEUTIC AGENT TO THE ADVENTITIA OF A VESSEL 审中-公开
标题翻译：用于将治疗药物混合并输送到血管的先天的方法
公开(公告)号：WO2005112569A3
公开(公告)日：2006-03-16
申请号：PCT/US2005015621
申请日：2005-05-04
申请人： MEDTRONIC VASCULAR INC , TREMBLE PATRICE , JUDD DIANNE , UDIPI KISHORE , CHENG PEIWEN , SUNDAR RANGARAJAN RON , PATEL KAUSHIK , TEDESCHI EUGENE
发明人： TREMBLE PATRICE , JUDD DIANNE , UDIPI KISHORE , CHENG PEIWEN , SUNDAR RANGARAJAN RON , PATEL KAUSHIK , TEDESCHI EUGENE
IPC分类号： A61F2/958 , A61M25/00 , A61K9/16
CPC分类号： A61M25/0084 , A61K9/16
摘要： The invention provides a method of delivering a therapeutic agent to the adventitia of a vessel using a catheter-based microsyringe. A therapeutic agent is formed into microparticles, which are dispersed throughout an appropriate liquid carrier to form a therapeutic mixture. A catheter is provided that includes a microsyringe operably attached to an actuator. The microsyringe includes a hollow needle in fluid communication with a therapeutic agent delivery conduit. The catheter is introduced into a target area of a vessel. The actuator is operated to thrust the needle into a wall of the vessel. The therapeutic mixture is supplied to the therapeutic agent delivery conduit and delivered through the conduit to the needle and thereby into the adventitia of the vessel. The actuator is again operated to withdraw the needle from the wall of the vessel and to enclose it within the actuator. The catheter is then removed from the vessel.
摘要翻译：本发明提供了使用基于导管的微量注射器将治疗剂递送至血管的外膜的方法。将治疗剂形成为微粒，其分散在整个合适的液体载体中以形成治疗性混合物。提供了一种导管，其包括可操作地附接到致动器的微注射器。微注射器包括与治疗剂输送导管流体连通的中空针。将导管引入血管的靶区域。操作致动器以将针推入容器的壁中。将治疗性混合物供应到治疗剂递送导管并通过导管输送到针，从而被输送到血管的外膜。致动器再次被操作以将针从容器的壁中抽出并将其封闭在致动器内。然后从血管中取出导管。

2. 发明专利

DE602004011847D1 未知
公开(公告)号：DE602004011847D1
公开(公告)日：2008-04-03
申请号：DE602004011847
申请日：2004-02-24
申请人： MEDTRONIC VASCULAR INC
发明人： CHENG PEIWEN , SUNDAR RANGARAJAN , PATEL KAUSHIK , UDIPI KISHORE
IPC分类号： A61L31/10 , A61F2/00 , A61F2/06 , A61L27/34 , A61L29/08
摘要： The present invention provides a system for treating a vascular condition, which includes a catheter; a stent coupled to the catheter, the stent including a stent framework; a phenoxy primer coating operably disposed on the stent framework; and a drug-polymer coating disposed on the phenoxy primer coating. The present invention also provides a drug-coated stent and a method of manufacturing a drug-coated stent.

3. 发明专利

DE602005021101D1 VERFAHREN UND SYSTEM ZUM FESTHALTEN EINES STENTS MIT EINEM KLEBSTOFF 未知
公开(公告)号：DE602005021101D1
公开(公告)日：2010-06-17
申请号：DE602005021101
申请日：2005-03-23
申请人： MEDTRONIC VASCULAR INC
发明人： ROGERS RONAN , DESHMUKH SUSHEEL , PATEL KAUSHIK
IPC分类号： A61F2/06 , A61F2/84

4. 发明专利

AT466546T 未知
公开(公告)号：AT466546T
公开(公告)日：2010-05-15
申请号：AT05734344
申请日：2005-03-23
申请人： MEDTRONIC VASCULAR INC
发明人： ROGERS RONAN , DESHMUKH SUSHEEL , PATEL KAUSHIK
IPC分类号： A61F2/06 , A61F2/84
摘要： The invention provides a method of manufacturing a system for treating a vascular condition. A catheter including an inflatable balloon is provided. A stent is positioned over the balloon. An adhesive material is applied between an inner surface of the stent and an outer surface of the balloon. The adhesive material is heated to above a melting point of the adhesive material. The adhesive material is cooled to below a melting point of the adhesive material to provide an adhesive bond that retains the stent to the catheter during vascular delivery, wherein the stent is released from the balloon following inflation and deflation of the balloon at a treatment site.

5. 发明专利

DE602004011847T2 未知
公开(公告)号：DE602004011847T2
公开(公告)日：2009-02-26
申请号：DE602004011847
申请日：2004-02-24
申请人： MEDTRONIC VASCULAR INC
发明人： CHENG PEIWEN , SUNDAR RANGARAJAN , PATEL KAUSHIK , UDIPI KISHORE
IPC分类号： A61L31/10 , A61F2/00 , A61F2/06 , A61L27/34 , A61L29/08
摘要： The present invention provides a system for treating a vascular condition, which includes a catheter; a stent coupled to the catheter, the stent including a stent framework; a phenoxy primer coating operably disposed on the stent framework; and a drug-polymer coating disposed on the phenoxy primer coating. The present invention also provides a drug-coated stent and a method of manufacturing a drug-coated stent.

6. 发明申请

WO2012151520A3 WAFER SCALE PACKAGING PLATFORM FOR TRANSCEIVERS 审中-公开
标题翻译：收货机的平均包装平台
公开(公告)号：WO2012151520A3
公开(公告)日：2013-01-10
申请号：PCT/US2012036582
申请日：2012-05-04
申请人： LIGHTWIRE LLC , SHASTRI KALPENDU , PATEL VIPULKUMAR , WEBSTER MARK , GOTHOSKAR PRAKASH , KACHRU RAVINDER , PATHAK SOHAM , YELAMARTY RAO V , DAUGHERTY THOMAS , DAMA BIPIN , PATEL KAUSHIK , DESAI KISHOR
发明人： SHASTRI KALPENDU , PATEL VIPULKUMAR , WEBSTER MARK , GOTHOSKAR PRAKASH , KACHRU RAVINDER , PATHAK SOHAM , YELAMARTY RAO V , DAUGHERTY THOMAS , DAMA BIPIN , PATEL KAUSHIK , DESAI KISHOR
IPC分类号： H01L25/16 , H01L25/18
CPC分类号： H01L25/50 , G02B6/423 , G02B6/4244 , G02B6/4245 , G02B6/4249 , G02B6/4257 , G02B6/426 , H01L25/167 , H01L2224/16225 , H01L2224/48091 , H01L2224/48227 , H01L2924/00014
摘要： A wafer scale implementation of an opto-electronic transceiver assembly process utilizes a silicon wafer as an optical reference plane and platform upon which all necessary optical and electronic components are simultaneously assembled for a plurality of separate transceiver modules. In particular, a silicon wafer is utilized as a "platform" (interposer) upon which all of the components for a multiple number of transceiver modules are mounted or integrated, with the top surface of the silicon interposer used as a reference plane for defining the optical signal path between separate optical components. Indeed, by using a single silicon wafer as the platform for a large number of separate transceiver modules, one is able to use a wafer scale assembly process, as well as optical alignment and testing of these modules.
摘要翻译：光电子收发器组件过程的晶片级实现利用硅晶片作为光学参考平面和平台，同时为多个单独的收发器模块组装所有必需的光学和电子部件。特别地，硅晶片被用作“平台”（插入器），在其上安装或集成多个收发器模块的所有组件，硅插入器的顶表面用作参考平面，用于定义分离光学元件之间的光信号路径。实际上，通过使用单个硅晶片作为大量单独的收发器模块的平台，可以使用晶片级组装过程以及这些模块的光学对准和测试。

7. 发明申请

WO2011003039A3 ANALYTE SENSORS AND METHODS OF MANUFACTURING SAME 审中-公开
标题翻译：分析传感器及其制造方法
公开(公告)号：WO2011003039A3
公开(公告)日：2011-04-14
申请号：PCT/US2010040842
申请日：2010-07-01
申请人： DEXCOM INC , SIMPSON PETER C , BOOCK ROBERT , NEALE PAUL V , BOHM SEBASTIAN , WIGHTLIN MATTHEW , PRYOR JACK , MITCHELL JASON , JACKSON JEFF , PATEL KAUSHIK , LLEVARES ANTONIO C
发明人： SIMPSON PETER C , BOOCK ROBERT , NEALE PAUL V , BOHM SEBASTIAN , WIGHTLIN MATTHEW , PRYOR JACK , MITCHELL JASON , JACKSON JEFF , PATEL KAUSHIK , LLEVARES ANTONIO C
IPC分类号： A61B5/145 , A61B5/1468
CPC分类号： A61B5/1473 , A61B5/14503 , A61B5/1451 , A61B5/14517 , A61B5/14532 , A61B5/14546 , A61B5/14865 , A61B2560/0223 , A61B2562/0209 , A61B2562/043 , A61B2562/125 , B05C3/10
摘要： Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system (800) comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system (800) comprises first and second elongated bodies El, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer (810) that separates the conductive layer (820) from the elongated body, a membrane layer deposited on top of the elongated bodies El, E2, and working electrodes (802', 802") formed by removing portions of the conductive layer (820) and the insulating layer (810), thereby exposing electroactive surface of the elongated bodies El, E2.
摘要翻译：提供分析物传感器及其制造方法，包括包含多轴灵活性的分析物传感器。例如，提供了包括两个工作电极和至少一个参考/对电极的多电极传感器系统（800）。传感器系统（800）包括第一和第二细长体E1，E2，每个由导电芯或具有沉积在其上的导电层的芯构成;绝缘层（810），其将导电层（820）与细长体，沉积在细长体E1，E2和通过去除导电层（820）和绝缘层（810）的部分形成的工作电极（802'，802“）之上的膜层，从而暴露电活性表面细长体E1，E2。

8. 发明申请

WO2010045482A3 INTRAGASTRIC DEVICE 审中-公开
公开(公告)号：WO2010045482A3
公开(公告)日：2010-09-02
申请号：PCT/US2009060881
申请日：2009-10-15
申请人： OBALON THERAPEUTICS INC , BRISTER MARK C , QUINTANA NELSON , PATEL KAUSHIK , DRAKE NEIL , LLEVARES ANTONIO , MARKOVIC DUBRAVKA , RASDAL ANDREW , VANDENBERG AMY
发明人： BRISTER MARK C , QUINTANA NELSON , PATEL KAUSHIK , DRAKE NEIL , LLEVARES ANTONIO , MARKOVIC DUBRAVKA , RASDAL ANDREW , VANDENBERG AMY
IPC分类号： A61M29/04 , A61M29/00 , A61M29/02 , A61M31/00
CPC分类号： A61F5/003 , A61B17/1204 , A61B17/12099 , A61B90/39 , A61B2090/3966 , A61F5/0036 , A61F5/0073 , A61F5/0083 , A61L31/088 , A61L31/10 , A61L2400/16 , A61L2420/02 , A61L2420/08 , A61M25/10185 , A61M25/1027 , A61M25/1029 , A61M31/002 , A61M2025/1031 , A61M2025/105 , Y10T156/1051
摘要： An implant configured for ingestion by a patient. After the implant has been swallowed by the patient and is disposed within the target location, e.g. the patient's stomach, an inflation subcomponent causes the implant to expand from a compact delivery state to an expanded, volume-occupying, deployed state. In the deployed state the implant creates a sensation of satiety in the patient stomach and thereby aids in limiting food intake and obesity. After a predetermined time a deflation subcomponent is actuated and the implant reduces in size so as to allow it to pass through the remainder of the patient's digestive track. The device may further incorporate tracking and visualization subcomponents, as well as pharmaceutical delivery subcomponents. In a preferred embodiment, a swallowable, intragastric volume-occupying device is provided comprising a compacted balloon 445 having therein a silicone head 441 with radioopacity ring 442, a silicone septum 443, an inoculation spacer 444, an inner container 446, and outer container 447.
摘要翻译：配置为由患者摄取的植入物。在植入物被患者吞咽并被置于目标位置内后，例如，患者的胃部，充气辅助部件导致植入物从紧凑的输送状态扩展到扩大的容量占用部署状态。在展开状态下，植入物在患者胃中产生饱腹感，从而有助于限制食物摄入和肥胖。在预定的时间之后，放气子组件被致动并且植入物尺寸减小以允许其穿过患者消化道的其余部分。该装置可以进一步包含跟踪和可视化子组件以及药物递送子组件。在一个优选实施例中，提供可吞咽的胃内体积占用装置，其包括其中具有不透射线环442的硅树脂头部441，硅树脂隔膜443，接种隔离物444，内部容器446和外部容器447的压缩气囊445 。

9. 发明申请

WO2011128737A3 PAPER SHREDDER WITH FEEDER 审中-公开
标题翻译：纸ER ER。。
公开(公告)号：WO2011128737A3
公开(公告)日：2012-03-01
申请号：PCT/IB2011000651
申请日：2011-03-25
申请人： ACCO UK LTD , ARIES PAUL A , PATEL KAUSHIK
发明人： ARIES PAUL A , PATEL KAUSHIK
IPC分类号： B02C18/00 , B02C18/22
CPC分类号： B02C18/0007 , B02C18/2225 , B02C18/2283 , B02C18/2291
摘要： A paper shredder comprising a housing, cutters positioned in the housing, a feeder base coupled to the housing and including a feeder slot, and a pressure plate mounted for movement above the feeder base. The pressure plate has a length perpendicular to the feeder slot that is less than 80% of a length of the feeder base. In one embodiment, the pressure plate includes two rollers positioned on opposing sides of the feeder slot (e.g., rotational about axes fixed relative to each other). The pressure plate preferably does not overlap with any aperture(s) in the feeder base. The paper shredder can also include a feeder door that substantially covers the entire feeder base and is pivoted at one end of the feeder door. The pressure plate can be mounted adjacent a bottom surface of the feeder door.
摘要翻译：一种破碎机，包括壳体，定位在壳体中的切割器，联接到壳体并包括进料器槽的进料器基座和安装成在进料器基座上方移动的压力板。压板的长度垂直于给料槽，小于进料器底座长度的80％。在一个实施例中，压板包括位于给料器槽的相对侧上的两个辊（例如，围绕相对于彼此固定的轴线的旋转）。压板优选地不与馈送器基座中的任何孔重叠。碎纸机还可以包括馈送器门，其基本上覆盖整个馈送器基座并且在馈送器门的一端枢转。压板可以靠近进料器门的底部表面安装。

10. 发明申请

WO2011128736A3 PAPER SHREDDER WITH STAPLE AND CLIP REMOVER 审中-公开
标题翻译：带有剪纸和夹子拆卸的纸张
公开(公告)号：WO2011128736A3
公开(公告)日：2012-01-05
申请号：PCT/IB2011000647
申请日：2011-03-25
申请人： ACCO UK LTD , ARIES PAUL A , PATEL KAUSHIK
发明人： ARIES PAUL A , PATEL KAUSHIK
IPC分类号： B02C18/00
CPC分类号： B02C18/2283 , B02C18/0007 , B02C18/2225 , B02C23/02 , B02C23/04 , B02C23/08 , B02C2018/003 , B02C2018/0046
摘要： A paper shredder comprising a housing, cutters positioned in the housing, and a feeder base adapted to support a stack of paper. The feeder base includes a feed slot and an aperture providing communication between a top surface of the feeder base and a waste area. An edge defines at least a portion of the aperture and is oriented at an angle oblique to the feeder slot. The edge can be positioned at an angle of 3 degrees to 70 degrees, and preferably at about 10 degrees relative to the feeder slot. Preferably, the edge includes a first section at an angle of between 3 degrees and 20 degrees relative to the feeder slot, and a second section at an angle of between 20 degrees and 45 degrees relative to the feeder slot. The shredder can further comprise a deflection member for deflecting clips falling into the aperture.
摘要翻译：一种纸粉碎机，包括壳体，定位在壳体中的切割器以及适于支撑一叠纸张的馈送器基座。馈送器基座包括馈送槽和提供馈送器基座的顶表面与废物区之间的连通的孔。边缘限定孔的至少一部分并且以与给料器槽倾斜的角度定向。边缘可以相对于给料槽定位成3度至70度的角度，优选地为约10度。优选地，所述边缘包括相对于所述给料槽而处于3度和20度之间的角度的第一部分，以及相对于所述进料器槽在20度和45度之间的角度处的第二部分。切碎机还可以包括用于偏转落入孔中的夹子的偏转构件。

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