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1. 发明申请

WO2006135791A3 PERIPHERAL NERVE FIELD STIMULATION AND SPINAL CORD STIMULATION 审中-公开
标题翻译：外周神经刺激和脊髓刺激
公开(公告)号：WO2006135791A3
公开(公告)日：2007-03-22
申请号：PCT/US2006022565
申请日：2006-06-09
申请人： MEDTRONIC INC , ROONEY ETHAN A , WAHLSTRAND CARL D , KING GARY W , CROSS THOMAS E JR , HERUTH KENNETH T , WACNIK PAUL W , EVANSON JEFFREY S
发明人： ROONEY ETHAN A , WAHLSTRAND CARL D , KING GARY W , CROSS THOMAS E JR , HERUTH KENNETH T , WACNIK PAUL W , EVANSON JEFFREY S
IPC分类号： A61N1/34 , A61N1/05 , A61N1/372
CPC分类号： A61N1/36071 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/0558 , A61N1/36021 , A61N1/37205 , A61N1/37211 , A61N1/375 , A61N1/3756
摘要： Delivery of peripheral nerve field stimulation (PNFS) in combination with one o more other therapies is described. The other therapy delivered in combination with PNF may be, for example, a different type of neurostimulation, such as spinal cord stimulation (SCS), or a drug. PNFS and the other therapy may be delivered simultaneously, in an alternating fashion, according to a schedule, and/or selectively, e.g., in response to a request received from a patient or clinician. A combination therapy that includes PNFS may be able to more completely address complex or multifocal pain than would be possible through delivery of either PNFS or other therapies alone. Further, the combination of PNFS with one or more other therapies may reduce the likelihood that neural accommodation will impair the perceived effectiveness PNFS or the other therapies.
摘要翻译：描述了外周神经区域刺激（PNFS）与一种或多种其他疗法的结合。与PNF组合递送的另一疗法可以是例如不同类型的神经刺激，例如脊髓刺激（SCS）或药物。 PNFS和其他治疗可以根据时间表以交替方式同时递送，和/或选择性地，例如响应于从患者或临床医生接收到的请求。包括PNFS的联合治疗可能能够更全面地解决复杂或多焦点疼痛，而不仅仅是通过传送PNFS或其他疗法来实现。此外，PNFS与一种或多种其它疗法的组合可以降低神经调节可能损害所感知的有效性PNFS或其他疗法的可能性。

2. 发明申请

WO2006135751A3 COMBINATION THERAPY INCLUDING PERIPHERAL NERVE FIELD STIMULATION 审中-公开
标题翻译：组合治疗包括外周神经网络刺激
公开(公告)号：WO2006135751A3
公开(公告)日：2007-02-15
申请号：PCT/US2006022490
申请日：2006-06-09
申请人： MEDTRONIC INC , ROONEY ETHAN A , WAHLSTRAND CARL D , KING GARY W , CROSS THOMAS E JR , HERUTH KENNETH T , WACNIK PAUL W , EVANSON JEFFREY S
发明人： ROONEY ETHAN A , WAHLSTRAND CARL D , KING GARY W , CROSS THOMAS E JR , HERUTH KENNETH T , WACNIK PAUL W , EVANSON JEFFREY S
IPC分类号： A61N1/34
CPC分类号： A61N1/36021 , A61M5/14 , A61M5/142 , A61M2205/054 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/0558 , A61N1/36017 , A61N1/36071 , A61N1/37211 , A61N1/375
摘要： Delivery of peripheral nerve field stimulation (PNFS) in combination with one or more other therapies is described. The other therapy delivered in combination with PNFS may be, for example, a different type of neurostimulation, such as spinal cord stimulation (SCS), or a drug. PNFS and the other therapy may be delivered simultaneously, in an alternating fashion, according to a schedule, and/or selectively, e.g., in response to a request received from a patient or clinician. A combination therapy that includes PNFS may be able to more completely address complex or multifocal pain than would be possible through delivery of either PNFS or other therapies alone. Further, the combination of PNFS with one or more other therapies may reduce the likelihood that neural accommodation will impair the perceived effectiveness PNFS or the other therapies.
摘要翻译：描述了外周神经区域刺激（PNFS）与一种或多种其他疗法的结合。与PNFS组合递送的另一疗法可以是例如不同类型的神经刺激，例如脊髓刺激（SCS）或药物。 PNFS和其他治疗可以根据时间表以交替方式同时递送，和/或选择性地，例如响应于从患者或临床医生接收到的请求。包括PNFS的联合治疗可能能够更全面地解决复杂或多焦点疼痛，而不仅仅是通过传送PNFS或其他疗法来实现。此外，PNFS与一种或多种其它疗法的组合可以降低神经调节可能损害所感知的有效性PNFS或其他疗法的可能性。

3. 发明申请

WO2006133445A3 IMPLANTABLE MEDICAL LEAD 审中-公开
标题翻译：可植入医疗领域
公开(公告)号：WO2006133445A3
公开(公告)日：2007-02-08
申请号：PCT/US2006022721
申请日：2006-06-09
申请人： MEDTRONIC INC , ROONEY ETHAN A , WAHLSTRAND CARL D , KING GARY W , CROSS THOMAS E , STONE RICHARD T
发明人： ROONEY ETHAN A , WAHLSTRAND CARL D , KING GARY W , CROSS THOMAS E , STONE RICHARD T
IPC分类号： A61N1/05
CPC分类号： A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36071 , A61N1/37211
摘要： The disclosure describes an implantable medical lead for delivering stimulation to a patient. Electrodes may be located on two or more surfaces of the lead to, for example, selectively deliver stimulation to one or more tissue layers within the patient. The lead may be implanted within or between intra-dermal, deep dermal, or subcutaneous tissue layers, and may be used to, for example, deliver peripheral nerve field stimulation to treat pain experienced by the patient at the site at which the lead is implanted. The lead may comprise a paddle lead or a multiple level lead, e.g., a lead having a plurality of flat or paddle shaped lead bodies arranged in substantially parallel planes. Further, the lead may include fixation structures on the distal end, proximal end, or both ends to prevent migration.
摘要翻译：本公开描述了用于将刺激递送给患者的可植入医疗引线。电极可以位于引线的两个或更多个表面上，以例如选择性地将刺激递送到患者体内的一个或多个组织层。铅可以植入在真皮内，深层皮肤或皮下组织层之内或之间，并且可以用于例如递送周围神经区域刺激以治疗患者在植入铅的部位所经历的疼痛。引线可以包括桨引线或多级引线，例如具有布置在基本上平行的平面中的多个扁平或桨状引线的引线。此外，引线可以包括远端，近端或两端的固定结构，以防止迁移。

4. 发明申请

WO2006133444A2 IMPLANTABLE MEDICAL DEVICE WITH ELECTRODES ON MULTIPLE HOUSING SURFACES 审中-公开
标题翻译：具有多个外壳表面的电极的可植入医疗装置
公开(公告)号：WO2006133444A2
公开(公告)日：2006-12-14
申请号：PCT/US2006022718
申请日：2006-06-09
申请人： MEDTRONIC INC , ROONEY ETHAN A , WAHLSTRAND CARL D , KING GARY W , CROSS THOMAS E , STONE RICHARD T
发明人： ROONEY ETHAN A , WAHLSTRAND CARL D , KING GARY W , CROSS THOMAS E , STONE RICHARD T
IPC分类号： A61N1/375 , A61N1/34 , A61N1/36
CPC分类号： A61N1/375 , A61N1/0504 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36071 , A61N1/3756
摘要： An implantable medical device (IMD) with a housing and electrodes on at least two surfaces of the housing is described. The surfaces may be, for example, opposed, substantially parallel surfaces, e.g., top and bottom surfaces. Location of electrodes on multiple surfaces of the housing may allow the IMD to deliver stimulation to a variety of tissues and with a variety of current field configurations. For example, the IMD may deliver peripheral nerve field stimulation (PNFS) to one or more tissue areas via electrodes selected from one or both of the surfaces to, for example, reduce the sensation of pain in a tissue area proximate to an implantation site of the IMD without targeting a specific nerve. The IMD may be implanted between or within intra-dermal, deep dermal, or subcutaneous layers of the tissue of the patient to deliver PNFS to any one or more of these layers.
摘要翻译：描述了在壳体的至少两个表面上具有壳体和电极的可植入医疗装置（IMD）。表面可以是例如相对的基本上平行的表面，例如顶部和底部表面。电极在壳体的多个表面上的位置可允许IMD将刺激递送到各种组织以及各种当前的现场配置。例如，IMD可以通过选自一个或两个表面的电极将外周神经区域刺激（PNFS）递送到一个或多个组织区域，以例如减少接近植入部位的组织区域中的疼痛感觉 IMD没有针对特定的神经。 IMD可以植入在患者组织的真皮内，深层皮肤或皮下层之间或内，以将PNFS递送到这些层中的任何一个或多个层。

5. 发明申请

WO2005102444A3 MRI-SAFE IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译： MRI-SAFE可植入医疗器械
公开(公告)号：WO2005102444A3
公开(公告)日：2007-06-07
申请号：PCT/US2004040082
申请日：2004-11-30
申请人： MEDTRONIC INC , WAHLSTRAND CARL D , SKIME ROBERT M , HRDLICKA GREGORY A , OLSEN JAMES M , BOLEA STEPHEN L
发明人： WAHLSTRAND CARL D , SKIME ROBERT M , HRDLICKA GREGORY A , OLSEN JAMES M , BOLEA STEPHEN L
IPC分类号： A61N1/36 , A61N1/05 , A61N1/34 , A61N1/375
CPC分类号： A61N1/08 , A61N1/05 , A61N1/0534 , A61N1/0551 , A61N1/086 , A61N1/36071
摘要： A medical lead is provided for use in a pulse stimulation system of the type which includes a pulse generator (102) for producing electrical stimulation therapy. The lead comprises an elongate insulating body (120) and at least one electrical conductor (106) within the insulating body (120). The conductor has a proximal end configured to be electrically coupled to the pulse generator and has a DC resistance in the range of 375-2000 ohms. At least one distal electrode (114) is coupled to the conductor (106).
摘要翻译：提供了一种用于包括用于产生电刺激疗法的脉冲发生器（102）的脉冲刺激系统的医疗引线。引线包括细长绝缘体（120）和绝缘体（120）内的至少一个电导体（106）。导体具有被配置为电耦合到脉冲发生器的近端，并具有在375-2000欧姆范围内的直流电阻。至少一个远端电极（114）耦合到导体（106）。

6. 发明申请

WO2007112004A3 IMPLANTABLE MEDICAL DEVICE AND LITHIUM BATTERY 审中-公开
标题翻译：可植入医疗设备和锂电池
公开(公告)号：WO2007112004A3
公开(公告)日：2007-11-01
申请号：PCT/US2007007251
申请日：2007-03-23
申请人： MEDTRONIC INC , SCOTT ERIK R , WAHLSTRAND CARL D , CONROY MARK J , KAST JOHN
发明人： SCOTT ERIK R , WAHLSTRAND CARL D , CONROY MARK J , KAST JOHN
IPC分类号： H01M2/26 , A61N1/372 , H01M2/30
CPC分类号： G01R33/56572 , A61B5/055 , A61B34/10 , A61N1/05 , A61N1/0529 , A61N1/0551 , A61N1/08 , A61N1/086 , A61N1/3605 , A61N1/36125 , A61N1/3718 , A61N1/375 , A61N1/3758 , A61N1/378 , G01R33/3875 , H01M2/0217 , H01M2/026 , H01M2/0275 , H01M2/0285 , H01M2/0404 , H01M2/1066 , H01M2/22 , H01M2/263 , H01M2/30 , H01M10/0431 , H01M10/052 , H01M10/0525 , H01M10/0587 , H01M2220/30 , Y10T29/49 , Y10T29/49002
摘要： A lithium battery includes a housing and a first electrode and a second electrode provided within the housing. A first tab is coupled to the first electrode and a second tab coupled to the second electrode. A pin is coupled to the second tab and extends to a location outside the housing. At least one of the first tab, the second tab, and the pin are formed from a material comprising vanadium.
摘要翻译：锂电池包括壳体以及设置在壳体内的第一电极和第二电极。第一接线片联接到第一电极，而第二接线片联接到第二电极。销被联接到第二突出部并且延伸到壳体外部的位置。第一接片，第二接片和销中的至少一个由包含钒的材料形成。

7. 发明申请

WO2012103419A3 IMPLANTABLE MEDICAL LEADS AND SYSTEMS THAT UTILIZE REFLECTION POINTS TO CONTROL INDUCED RADIO FREQUENCY ENERGY 审中-公开
标题翻译：使用反射点控制诱发无线电频率的可植入医疗领域和系统
公开(公告)号：WO2012103419A3
公开(公告)日：2013-01-10
申请号：PCT/US2012022868
申请日：2012-01-27
申请人： MEDTRONIC INC , WAHLSTRAND CARL D , HOEGH THOMAS B
发明人： WAHLSTRAND CARL D , HOEGH THOMAS B
IPC分类号： A61N1/05 , A61N1/08
CPC分类号： A61N1/08 , A61N1/05 , A61N1/086
摘要： Implantable medical leads and systems utilize reflection points within the lead to control radio frequency current that has been induced onto one or more filars. The radio frequency current may be controlled by the reflection points to block at least some of the radio frequency current from reaching an electrode of the lead and to dissipate at least some of the radio frequency current as heat on the filar. Controlling the radio frequency current thereby reduces the amount that is dissipated into bodily tissue through one or more electrodes of the lead and reduces the likelihood of tissue damage. The reflection points may be created by physical changes such as to material or size in the filar and/or in insulation layers that may be present such as an inner jacket about the filar and an outer jacket formed by the body of the lead.
摘要翻译：植入式医疗引线和系统利用引线内的反射点来控制已被诱导到一个或多个丝状体上的射频电流。射频电流可以由反射点控制，以阻止射频电流中的至少一些到达引线的电极，并将至少一些射频电流作为热丝散布在丝状体上。控制射频电流从而减少通过引线的一个或多个电极消散到身体组织中的量，并减少了组织损伤的可能性。反射点可以通过物理变化产生，例如在丝状物和/或可能存在的绝缘层中的材料或尺寸，例如围绕丝状物的内护套和由引线主体形成的外护套。

8. 发明申请

WO2007112044A3 IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：可植入医疗器械
公开(公告)号：WO2007112044A3
公开(公告)日：2007-12-21
申请号：PCT/US2007007337
申请日：2007-03-23
申请人： MEDTRONIC INC , WAHLSTRAND CARL D , CONROY MARK J , KAST JOHN , SCOTT ERIK R
发明人： WAHLSTRAND CARL D , CONROY MARK J , KAST JOHN , SCOTT ERIK R
IPC分类号： A61N1/32
CPC分类号： G01R33/56572 , A61B5/055 , A61B34/10 , A61N1/05 , A61N1/0529 , A61N1/0551 , A61N1/08 , A61N1/086 , A61N1/3605 , A61N1/36125 , A61N1/3718 , A61N1/375 , A61N1/3758 , A61N1/378 , G01R33/3875 , H01M2/0217 , H01M2/026 , H01M2/0275 , H01M2/0285 , H01M2/0404 , H01M2/1066 , H01M2/22 , H01M2/263 , H01M2/30 , H01M10/0431 , H01M10/052 , H01M10/0525 , H01M10/0587 , H01M2220/30 , Y10T29/49 , Y10T29/49002
摘要： An implantable medical device includes a housing and a circuit board provided within the housing. The circuit board includes a plurality of electronic components electrically coupled thereto. At least one non-functional component is provided on the circuit board and formed from a material that has an electromagnetic permeability configured to reduce the amount of image distortion caused by at least one of the plurality of electronic components when the device is subject to a magnetic field during an MRI scan.
摘要翻译：可植入医疗装置包括壳体和设置在壳体内的电路板。电路板包括与其电耦合的多个电子部件。至少一个非功能部件设置在电路板上，并且由具有电磁渗透性的材料形成，该材料被配置为当该器件经受磁性时减少由至少一个电子元件引起的图像失真量在MRI扫描期间。

9. 发明申请

WO2012068385A2 IMPLANTABLE MEDICAL DEVICE WITH SWAPPABLE HEADERS 审中-公开
标题翻译：带可折叠接头的可植入医疗设备
公开(公告)号：WO2012068385A2
公开(公告)日：2012-05-24
申请号：PCT/US2011061208
申请日：2011-11-17
申请人： MEDTRONIC INC , SEELEY DALE F , RAHN JASON D , HEGLAND MICHAEL T , WAHLSTRAND CARL D
发明人： SEELEY DALE F , RAHN JASON D , HEGLAND MICHAEL T , WAHLSTRAND CARL D
IPC分类号： A61N1/375
CPC分类号： A61N1/3752 , A61N1/3754 , H01R24/00 , H01R24/76 , H01R2107/00 , Y10T29/49169
摘要： An implantable electrical medical device system includes a device body portion having a plurality of contacts operably coupled to discrete channels of electronics. One or more swappable headers may be attached to the device body portion by an end user, such as an implanting physician, to operably couple internal lead receptacle contacts in the header to the contacts of the device body portion. The swappable headers may have lead receptacles configured to receive differing types or combinations of leads, allowing an end user to select one or more appropriate headers as desired.
摘要翻译：一种可植入的电医疗设备系统包括设备主体部分，该设备主体部分具有可操作地耦合到离散电子通道的多个触点。一个或多个可置换的头部可由最终用户（例如植入医师）附接到装置主体部分，以将头部中的内部引线插座触点可操作地耦合到装置主体部分的触点。可交换头部可以具有配置成接收不同类型或引线组合的引线插座，允许最终用户根据需要选择一个或多个适当的头部。

10. 发明申请

WO2007112070A3 IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：可植入的医疗设备
公开(公告)号：WO2007112070A3
公开(公告)日：2007-11-29
申请号：PCT/US2007007384
申请日：2007-03-23
申请人： MEDTRONIC INC , KAST JOHN , WAHLSTRAND CARL D , CONROY MARK J , SCOTT ERIK R
发明人： KAST JOHN , WAHLSTRAND CARL D , CONROY MARK J , SCOTT ERIK R
IPC分类号： A61N1/32
CPC分类号： G01R33/56572 , A61B5/055 , A61B34/10 , A61N1/05 , A61N1/0529 , A61N1/0551 , A61N1/08 , A61N1/086 , A61N1/3605 , A61N1/36125 , A61N1/3718 , A61N1/375 , A61N1/3758 , A61N1/378 , G01R33/3875 , H01M2/0217 , H01M2/026 , H01M2/0275 , H01M2/0285 , H01M2/0404 , H01M2/1066 , H01M2/22 , H01M2/263 , H01M2/30 , H01M10/0431 , H01M10/052 , H01M10/0525 , H01M10/0587 , H01M2220/30 , Y10T29/49 , Y10T29/49002
摘要： An implantable medical device includes a housing having a shimming material provided in contact with an inner surface of the housing to reduce the amount of image distortion caused by the implantable medical device when the device is subjected to MRI scans.
摘要翻译：可植入医疗装置包括壳体，该壳体具有提供为与壳体的内表面接触的匀场材料，以减少当装置经受MRI扫描时由可植入医疗装置引起的图像失真的量。

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