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1. 发明申请

WO2010126975A1 A SHIELDED IMPLANTABLE MEDICAL LEAD WITH REDUCED TORSIONAL STIFFNESS 审中-公开
标题翻译：具有降低扭转刚度的屏蔽式可植入医疗引线
公开(公告)号：WO2010126975A1
公开(公告)日：2010-11-04
申请号：PCT/US2010/032719
申请日：2010-04-28
申请人： MEDTRONIC, INC. , HEGLAND, Michael , SALMINEN, Gary W. , STONE, Richard T. , BONDHUS, Spencer
发明人： HEGLAND, Michael , SALMINEN, Gary W. , STONE, Richard T. , BONDHUS, Spencer
IPC分类号： A61N1/08 , H01B11/18
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： Shields within implantable leads increase the torsional stiffness of the leads. The torsional stiffness may be reduced by cutting the shield axially to break the circumferential mechanical continuity of the shield. The circumferential shielding continuity of the shield may be re-established to preserve the shielding effect in various manners. The shield may overlap onto itself to close the slot created by the cut. A shield patch may be placed across the slot created by the cut. The shield may be located between two insulation layers of the lead. The shield may be cut and then the slot closed prior to application of the outer insulation layer. The outer insulation layer may then be added over the shield. The outer insulation layer may be compliant so that once covered, the circumferential mechanical continuity of the shield remains broken.
摘要翻译：可植入引线内的护盾增加引线的扭转刚度。可以通过轴向切割屏蔽来破坏屏蔽件的周向机械连续性来减小扭转刚度。可以重新建立屏蔽件的圆周屏蔽连续性，以各种方式保持屏蔽效果。屏蔽可能会重叠在自身上，以关闭由切割创建的槽。屏蔽贴片可以放置在由切口产生的狭槽上。屏蔽可以位于引线的两个绝缘层之间。屏蔽可以被切割，然后在施加外绝缘层之前关闭槽。然后可以将外部绝缘层添加到屏蔽上。外绝缘层可以是柔性的，使得一旦被覆盖，屏蔽层的周向机械连续性保持断裂。

2. 发明申请

WO2010126943A2 GROUNDING OF A SHIELD WITHIN AN IMPLANTABLE MEDICAL LEAD 审中-公开
标题翻译：在可植入医疗领域接触皮肤
公开(公告)号：WO2010126943A2
公开(公告)日：2010-11-04
申请号：PCT/US2010/032671
申请日：2010-04-28
申请人： MEDTRONIC, INC. , OLSEN, James M. , KLARDIE, Michael R. , STONE, Richard T. , CAI, Chad Q. , BONDHUS, Spencer , CONROY, Mark J. , ABRAHAM, Timothy R.
发明人： OLSEN, James M. , KLARDIE, Michael R. , STONE, Richard T. , CAI, Chad Q. , BONDHUS, Spencer , CONROY, Mark J. , ABRAHAM, Timothy R.
IPC分类号： A61N1/08 , A61N1/37 , A61N1/05
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： Grounding of a shield that is located in an implantable medical lead may be done in many ways. The shield may be grounded directly to tissue from the lead body at one or more points along the lead body. The pathway for grounding may be a direct current pathway or be capacitively coupled. The pathway for grounding may utilize an exposed or nearly exposed shield at one or more points along the lead body. A jacket forming the lead body may have an outer layer removed at these points to provide the RF pathway to ground. Alternatively, the jacket may be doped with conductive particles at these points. Metal conductors such as ring electrodes and/or lead anchors may be attached to the lead at one or more points to provide the RF pathway to ground.
摘要翻译：位于植入式医疗引线中的护罩的接地可以以许多方式进行。屏蔽件可以沿着引线主体的一个或多个点从引线体直接接地到组织。用于接地的途径可以是直流电路或电容耦合。用于接地的路径可以沿着引线主体在一个或多个点处利用暴露或几乎暴露的屏蔽。形成引线体的护套可以在这些点处具有去除的外层，以将RF通路提供到地面。或者，夹套可以在这些点处掺杂导电颗粒。诸如环形电极和/或引线锚的金属导体可以在一个或多个点附接到引线，以将RF通路提供到地。

3. 发明申请

WO2010126939A1 A SHIELDED IMPLANTABLE MEDICAL LEAD WITH GUARDED TERMINATION 审中-公开
标题翻译：带有保护终止的屏蔽式可植入式医疗引线
公开(公告)号：WO2010126939A1
公开(公告)日：2010-11-04
申请号：PCT/US2010/032666
申请日：2010-04-28
申请人： MEDTRONIC, INC. , STONE, Richard T. , CONROY, Mark J. , LIU, Wanzhan , SALMINEN, Gary W.
发明人： STONE, Richard T. , CONROY, Mark J. , LIU, Wanzhan , SALMINEN, Gary W.
IPC分类号： A61N1/05 , A61N1/08 , H01R9/05 , H01B11/18
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： Implantable medical leads include a shield that is guarded at a termination by having a first portion and second portion of the shield, where the first portion is between a termination of the shield at the second portion and an inner insulation layer surrounding the filars. The first portion may reduce the coupling of RF energy from the termination of the shield at the second portion to the filars. The first and second portions may be part of a continuous shield, where the first and second portions are separated by an inversion of the shield. The first and second portions may instead be separate pieces. The first portion may be noninverted residing between the termination at the second portion and inner layers, or the first portion may be inverted to create first and second sub-portions. The shield termination at the second portion is between the first and second sub-portions.
摘要翻译：可植入医疗引线包括通过具有屏蔽件的第一部分和第二部分在端子处被保护的屏蔽件，其中第一部分位于第二部分处的屏蔽件的终端和围绕线圈的内部绝缘层之间。第一部分可以减少RF能量从第二部分处的屏蔽端接到丝状体的耦合。第一和第二部分可以是连续屏蔽的一部分，其中第一和第二部分被屏蔽的反转分开。第一和第二部分可以是分开的部分。第一部分可以位于第二部分的终端和内层之间，或者第一部分可以被倒置以产生第一和第二子部分。第二部分处的屏蔽终端位于第一和第二子部分之间。

4. 发明申请

WO2010126871A2 TERMINATION OF A SHIELD WITHIN AN IMPLANTABLE MEDICAL LEAD 审中-公开
标题翻译：在可植入医疗领域终止护理
公开(公告)号：WO2010126871A2
公开(公告)日：2010-11-04
申请号：PCT/US2010032526
申请日：2010-04-27
申请人： MEDTRONIC INC , MEHDIZADEH BRUCE R , STOLZ BRIAN T , KLARDIE MICHAEL R , KERN MICHAEL J , OLSEN JAMES M , STONE RICHARD T , CAI CHAD Q , BONDHUS SPENCER , CONROY MARK J , ABRAHAM TIMOTHY R
发明人： MEHDIZADEH BRUCE R , STOLZ BRIAN T , KLARDIE MICHAEL R , KERN MICHAEL J , OLSEN JAMES M , STONE RICHARD T , CAI CHAD Q , BONDHUS SPENCER , CONROY MARK J , ABRAHAM TIMOTHY R
IPC分类号： A61N1/05
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： A shield located within an implantable medical lead may be terminated in various ways at a metal connector. The shield may be terminated by various joints including butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. The shield may terminate with a physical and electrical connection to a single metal connector. The shield may terminate with a physical and electrical connection by passing between an overlapping pair of inner and outer metal connectors. The metal connectors may include features such as teeth or threads that penetrate the insulation layers of the lead. The shield may terminate with a physical and electrical connection by exiting a jacket of a lead adjacent to a metal connector and lapping onto the metal connector.
摘要翻译：位于可植入医疗引线内的护罩可以以各种方式在金属连接器处终止。屏蔽层可以由围绕引线的绝缘层和绝缘延伸部之间的各种接头（包括对接，围巾，搭接或其他接头）终止。屏蔽可以通过与单个金属连接器的物理和电连接终止。屏蔽可以通过在重叠的一对内部和外部金属连接器之间通过物理和电连接终止。金属连接器可以包括贯穿引线的绝缘层的诸如齿或线的特征。通过离开与金属连接器相邻的引线的护套并且研磨到金属连接器上，屏蔽件可以通过物理和电连接终止。

5. 发明申请

WO2008130408A1 IMPLANTABLE MEDICAL ELECTRICAL LEAD AND CONNECTOR ASSEMBLY 审中-公开
标题翻译：可植入医用电线和连接器总成
公开(公告)号：WO2008130408A1
公开(公告)日：2008-10-30
申请号：PCT/US2007/067064
申请日：2007-04-20
申请人： MEDTRONIC, INC. , ALEXANDER, James A. , OLSEN, James M. , CAI, Chad Q. , SCHNEIDER, Kristin J. , SKAKOON, James G. , STONE, Richard T.
发明人： ALEXANDER, James A. , OLSEN, James M. , CAI, Chad Q. , SCHNEIDER, Kristin J. , SKAKOON, James G. , STONE, Richard T.
IPC分类号： A61N1/05 , A61N1/375 , H01R13/52 , H01R13/64
CPC分类号： A61N1/3752 , A61B2562/227 , A61N1/05 , H01R13/5224 , H01R13/64 , H01R2201/12
摘要： An implantable medical system that includes an implantable electrical lead (24) having a lead body (11) having a connector portion (17) wherein at least the connector portion of the lead body has an axial cross section that is substantially non-circular; and a connector block (51) that is configured to be operably coupled to the implantable electrical lead (24), wherein the connector block includes a lumen (52) having an inner surface that is configured to be complementary to the outer surface of at least the connector portion of the lead body. Leads and connector blocks are also discussed.
摘要翻译：一种可植入医疗系统，其包括具有连接器部分（17）的引线本体（11）的可植入电引线（24），其中所述引线主体的至少所述连接器部分具有基本上非圆形的轴向截面; 以及连接器块（51），其被构造成可操作地耦合到所述可植入电引线（24），其中所述连接器块包括内腔（52），所述内腔具有内表面，所述内表面构造成至少与外表面互补引线体的连接器部分。还讨论了引线和连接器块。

6. 发明申请

WO2008111986A1 MEDICAL DEVICE ELECTRICAL LEAD DESIGN FOR PREVENTING TRANSMITTANCE OF UNSAFE CURRENTS TO A PATIENT 审中-公开
标题翻译：医疗设备电气导线设计，用于防止不安全电流向病人发送
公开(公告)号：WO2008111986A1
公开(公告)日：2008-09-18
申请号：PCT/US2007/067309
申请日：2007-04-24
申请人： MEDTRONIC, INC. , STONE, Richard, T.
发明人： STONE, Richard, T.
IPC分类号： A61N1/37 , H02H5/04 , A61B19/00
CPC分类号： A61N1/05 , A61B2090/0481 , A61N1/0534 , A61N1/0551 , A61N1/056 , A61N1/086
摘要： An electrical lead including a conductor assembly, an electrode, and a thermally sensitive material. The conductor assembly has one or more conductors. The electrode is in electrical communication with one of the conductors and has an outer contact adapted for contacting adjacent body tissue of a patient. The thermally sensitive material is electrically connected between the one conductor and the electrode outer contact, and is configured to exhibit high impedance in the presence of currents considered unsafe to the patient, thereby preventing the unsafe currents from flowing through the thermally sensitive material and through the electrode outer contact potentially causing the adjacent body tissue to increase in temperature to an unsafe level. The unsafe currents cause the thermally sensitive material to increase in temperature, thereby causing the material to transition to a high impedance state.
摘要翻译：包括导体组件，电极和热敏材料的电引线。导体组件具有一个或多个导体。电极与导体中的一个电连通，并且具有适于接触患者的相邻身体组织的外部接触。感热材料电连接在一个导体和电极外触点之间，并且被配置为在存在被认为对患者不安全的电流的情况下呈现高阻抗，由此防止不安全电流流过热敏材料并通过电极外部接触可能导致相邻的身体组织将温度升高到不安全的水平。不安全的电流导致热敏材料的温度升高，从而导致材料转变到高阻抗状态。

7. 发明申请

WO2006133445A2 IMPLANTABLE MEDICAL LEAD 审中-公开
标题翻译：可植入医疗领域
公开(公告)号：WO2006133445A2
公开(公告)日：2006-12-14
申请号：PCT/US2006/022721
申请日：2006-06-09
申请人： MEDTRONIC, INC. , ROONEY, Ethan, A. , WAHLSTRAND, Carl, D. , KING, Gary, W. , CROSS, Thomas, E. , STONE, Richard, T.
发明人： ROONEY, Ethan, A. , WAHLSTRAND, Carl, D. , KING, Gary, W. , CROSS, Thomas, E. , STONE, Richard, T.
IPC分类号： A61N1/05
CPC分类号： A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36071 , A61N1/37211
摘要： The disclosure describes an implantable medical lead for delivering stimulation to a patient. Electrodes may be located on two or more surfaces of the lead to, for example, selectively deliver stimulation to one or more tissue layers within the patient. The lead may be implanted within or between intra-dermal, deep dermal, or subcutaneous tissue layers, and may be used to, for example, deliver peripheral nerve field stimulation to treat pain experienced by the patient at the site at which the lead is implanted. The lead may comprise a paddle lead or a multiple level lead, e.g., a lead having a plurality of flat or paddle shaped lead bodies arranged in substantially parallel planes. Further, the lead may include fixation structures on the distal end, proximal end, or both ends to prevent migration.
摘要翻译：本公开描述了用于将刺激递送给患者的可植入医疗引线。电极可以位于引线的两个或更多个表面上，以例如选择性地将刺激递送到患者体内的一个或多个组织层。铅可以植入在真皮内，深层皮肤或皮下组织层之内或之间，并且可以用于例如递送周围神经域刺激，以治疗患者在植入铅的部位所经历的疼痛。引线可以包括桨引线或多级引线，例如具有布置在基本上平行的平面中的多个扁平或桨状引线的引线。此外，引线可以包括远端，近端或两端的固定结构，以防止迁移。

8. 发明申请

WO2010126887A1 TERMINATION OF A SHIELD WITHIN AN IMPLANTABLE MEDICAL LEAD 审中-公开
标题翻译：在可植入医疗领域终止护理
公开(公告)号：WO2010126887A1
公开(公告)日：2010-11-04
申请号：PCT/US2010/032567
申请日：2010-04-27
申请人： MEDTRONIC, INC. , KERN, Michael, J. , OLSEN, James, M. , KLARDIE, Michael, R. , STONE, Richard T. , CAI, Chad, Q. , BONDHUS, Spencer , CONROY, Mark, J. , ABRAHAM, Timothy, R. , STOLZ, Brian, T.
发明人： KERN, Michael, J. , OLSEN, James, M. , KLARDIE, Michael, R. , STONE, Richard T. , CAI, Chad, Q. , BONDHUS, Spencer , CONROY, Mark, J. , ABRAHAM, Timothy, R. , STOLZ, Brian, T.
IPC分类号： A61N1/08 , A61M25/00
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： A shield located within an implantable medical lead may be terminated in various ways. The shield may be terminated by butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. For lap joints, a portion of an outer insulation layer may be removed and a replacement outer insulation layer is positioned in place of the removed outer insulation layer, where the replacement layer extends beyond an inner insulation layer and the shield. The replacement layer may also lap onto a portion of the insulation extension. Barbs may be located between the replacement layer and the inner insulation layer or the insulation extension. The shield wires have ends at the termination point that may be folded over individually or may be capped with a ring located within one of the insulation layers of the jacket.
摘要翻译：位于可植入医疗引线内的护罩可以以各种方式终止。护罩可以通过对接，围巾，搭接或围绕导线的绝缘层与绝缘延伸部分之间的其他接头来终止。对于搭接接头，可以去除外部绝缘层的一部分，并且替换外部绝缘层被定位成代替去除的外部绝缘层，其中替换层延伸超出内部绝缘层和屏蔽。替换层也可以搭接在绝缘延伸部分的一部分上。倒钩可以位于更换层和内绝缘层之间或绝缘延伸部分。屏蔽线在终止点处具有可以单独折叠的端部，或者可以用位于护套的绝缘层之一内的环来封盖。

9. 发明申请

WO2010126871A3 TERMINATION OF A SHIELD WITHIN AN IMPLANTABLE MEDICAL LEAD 审中-公开
公开(公告)号：WO2010126871A3
公开(公告)日：2010-11-04
申请号：PCT/US2010/032526
申请日：2010-04-27
申请人： MEDTRONIC, INC. , MEHDIZADEH, Bruce R. , STOLZ, Brian T. , KLARDIE, Michael R. , KERN, Michael J. , OLSEN, James M. , STONE, Richard T. , CAI, Chad Q. , BONDHUS, Spencer , CONROY, Mark J. , ABRAHAM, Timothy R.
发明人： MEHDIZADEH, Bruce R. , STOLZ, Brian T. , KLARDIE, Michael R. , KERN, Michael J. , OLSEN, James M. , STONE, Richard T. , CAI, Chad Q. , BONDHUS, Spencer , CONROY, Mark J. , ABRAHAM, Timothy R.
IPC分类号： A61N1/05
摘要： A shield located within an implantable medical lead may be terminated in various ways at a metal connector. The shield may be terminated by various joints including butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. The shield may terminate with a physical and electrical connection to a single metal connector. The shield may terminate with a physical and electrical connection by passing between an overlapping pair of inner and outer metal connectors. The metal connectors may include features such as teeth or threads that penetrate the insulation layers of the lead. The shield may terminate with a physical and electrical connection by exiting a jacket of a lead adjacent to a metal connector and lapping onto the metal connector.

10. 发明申请

WO2007100428A1 ELECTRICAL AND ACTIVATION FIELD MODELS FOR CONFIGURING STIMULATION THERAPY 审中-公开
标题翻译：电动和激活用于配置刺激治疗的现场模型
公开(公告)号：WO2007100428A1
公开(公告)日：2007-09-07
申请号：PCT/US2007/002047
申请日：2007-01-24
申请人： MEDTRONIC, Inc. , STONE, Richard, T. , BALL, Warren, W. , WAHLSTRAND, Carl, D. , GOETZ, Steven, M. , OTTEN, Lynn, M.
发明人： STONE, Richard, T. , BALL, Warren, W. , WAHLSTRAND, Carl, D. , GOETZ, Steven, M. , OTTEN, Lynn, M.
IPC分类号： A61N1/372
CPC分类号： A61N1/37247 , A61N1/0529 , A61N1/0531 , A61N1/0534 , A61N1/0551 , A61N1/36082
摘要： The disclosure describes a method and system that generates an electrical field model of defined stimulation therapy arid displays the electrical field model to a user via a user interface. The electrical field model is generated based upon a patient anatomy and stimulation parameters to illustrate which areas of a patient anatomical region will be covered by the electrical field during therapy. In addition, a neuron model may be applied to the electrical field model to generate an activation field model. The activation field model indicates which neurons will be activated by the electrical field in the anatomical region. These field models may be used by a clinician to determine effective therapy prior to stimulation delivery. In particular, the field models may be beneficial when programming non axi-syrnmetric, or three-dimensional (3D), leads which allow greater flexibility in creating stimulation fields.
摘要翻译：本公开描述了一种产生定义的刺激疗法的电场模型的方法和系统，并且经由用户界面向用户显示电场模型。基于患者解剖学和刺激参数产生电场模型，以说明在治疗期间患者解剖区域的哪些区域将被电场覆盖。此外，神经元模型可以应用于电场模型以产生激活场模型。激活场模型指示哪个神经元将被解剖区域中的电场激活。临床医生可以使用这些现场模型来确定在刺激递送之前的有效治疗。特别地，当编程非轴向或三维（3D）导线时，现场模型可能是有益的，这些导线在创建刺激场方面具有更大的灵活性。

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