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1. 发明申请

WO2010126943A3 GROUNDING OF A SHIELD WITHIN AN IMPLANTABLE MEDICAL LEAD 审中-公开
标题翻译：在可植入医疗领域接触皮肤
公开(公告)号：WO2010126943A3
公开(公告)日：2011-02-17
申请号：PCT/US2010032671
申请日：2010-04-28
申请人： MEDTRONIC INC , OLSEN JAMES M , KLARDIE MICHAEL R , STONE RICHARD T , CAI CHAD Q , BONDHUS SPENCER , CONROY MARK J , ABRAHAM TIMOTHY R
发明人： OLSEN JAMES M , KLARDIE MICHAEL R , STONE RICHARD T , CAI CHAD Q , BONDHUS SPENCER , CONROY MARK J , ABRAHAM TIMOTHY R
IPC分类号： A61N1/08 , A61N1/05 , A61N1/37
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： Grounding of a shield that is located in an implantable medical lead may be done in many ways. The shield may be grounded directly to tissue from the lead body at one or more points along the lead body. The pathway for grounding may be a direct current pathway or be capacitively coupled. The pathway for grounding may utilize an exposed or nearly exposed shield at one or more points along the lead body. A jacket forming the lead body may have an outer layer removed at these points to provide the RF pathway to ground. Alternatively, the jacket may be doped with conductive particles at these points. Metal conductors such as ring electrodes and/or lead anchors may be attached to the lead at one or more points to provide the RF pathway to ground.
摘要翻译：位于可植入医疗引线中的护罩的接地可以以许多方式进行。屏蔽层可以沿着引线主体的一个或多个点从引线体直接接地到组织上。接地的途径可以是直流电路或电容耦合。用于接地的路径可以沿着引线体在一个或多个点处利用暴露或接近暴露的屏蔽。形成引线体的护套可以在这些点处具有去除的外层，以将RF通路提供到地面。或者，夹套可以在这些点处掺杂导电颗粒。诸如环形电极和/或引线锚的金属导体可以在一个或多个点附接到引线，以将RF通路提供到地。

2. 发明申请

WO2010126884A3 GROUNDING OF A SHIELD WITHIN AN IMPLANTABLE MEDICAL LEAD 审中-公开
标题翻译：可植入医用导线的屏蔽层接地
公开(公告)号：WO2010126884A3
公开(公告)日：2010-12-23
申请号：PCT/US2010032560
申请日：2010-04-27
申请人： MEDTRONIC INC , OLSEN JAMES M , KLARDIE MICHAEL R , STONE RICHARD T , CAI CHAD Q , BONDHUS SPENCER , CONROY MARK J , ABRAHAM TIMOTHY R
发明人： OLSEN JAMES M , KLARDIE MICHAEL R , STONE RICHARD T , CAI CHAD Q , BONDHUS SPENCER , CONROY MARK J , ABRAHAM TIMOTHY R
IPC分类号： A61N1/05 , A61N1/08 , A61N1/375
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： Grounding of a shield that is located in an implantable medical lead may be done in many ways. The ground pathway may couple to the shield at a point that is outside of a header of an implantable medical device to which the implantable medical lead is attached. The ground pathway may couple to the shield at a point that is within the header of the implantable medical device. The ground pathway may terminate at the metal can of the implantable medical device. As another option, the ground pathway may terminate at a ground plate that is mounted to the header. The ground pathway may be direct current coupled from the shield to the can or ground plate. Alternatively, the ground pathway may include one or more capacitive couplings that provide a pathway for induced radio frequency current.
摘要翻译：位于植入式医疗导线中的屏蔽层的接地可以通过许多方式完成。接地路径可以在可植入医疗设备所附接的可植入医疗设备的头部外部的点处耦合到屏蔽。接地路径可以在植入式医疗装置的头部内的点处耦合到护罩。接地路径可以终止于可植入医疗设备的金属罐。作为另一种选择，地面通路可以终止于安装到插头的接地板。接地路径可以是从屏蔽耦合到罐或接地板的直流电。或者，接地路径可以包括提供感应射频电流的路径的一个或多个电容耦合。

3. 发明申请

WO2010126871A2 TERMINATION OF A SHIELD WITHIN AN IMPLANTABLE MEDICAL LEAD 审中-公开
标题翻译：在可植入医疗领域终止护理
公开(公告)号：WO2010126871A2
公开(公告)日：2010-11-04
申请号：PCT/US2010032526
申请日：2010-04-27
申请人： MEDTRONIC INC , MEHDIZADEH BRUCE R , STOLZ BRIAN T , KLARDIE MICHAEL R , KERN MICHAEL J , OLSEN JAMES M , STONE RICHARD T , CAI CHAD Q , BONDHUS SPENCER , CONROY MARK J , ABRAHAM TIMOTHY R
发明人： MEHDIZADEH BRUCE R , STOLZ BRIAN T , KLARDIE MICHAEL R , KERN MICHAEL J , OLSEN JAMES M , STONE RICHARD T , CAI CHAD Q , BONDHUS SPENCER , CONROY MARK J , ABRAHAM TIMOTHY R
IPC分类号： A61N1/05
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： A shield located within an implantable medical lead may be terminated in various ways at a metal connector. The shield may be terminated by various joints including butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. The shield may terminate with a physical and electrical connection to a single metal connector. The shield may terminate with a physical and electrical connection by passing between an overlapping pair of inner and outer metal connectors. The metal connectors may include features such as teeth or threads that penetrate the insulation layers of the lead. The shield may terminate with a physical and electrical connection by exiting a jacket of a lead adjacent to a metal connector and lapping onto the metal connector.
摘要翻译：位于可植入医疗引线内的护罩可以以各种方式在金属连接器处终止。屏蔽层可以由围绕引线的绝缘层和绝缘延伸部之间的各种接头（包括对接，围巾，搭接或其他接头）终止。屏蔽可以通过与单个金属连接器的物理和电连接终止。屏蔽可以通过在重叠的一对内部和外部金属连接器之间通过物理和电连接终止。金属连接器可以包括贯穿引线的绝缘层的诸如齿或线的特征。通过离开与金属连接器相邻的引线的护套并且研磨到金属连接器上，屏蔽件可以通过物理和电连接终止。

4. 发明申请

WO2010062988A3 PATIENT PROGRAMMER WITH AUTOMATED MRI COMPATIBILITY VERIFICATION FOR ACTIVE IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：具有自动化MRI兼容性验证的患者编程器，用于活性可植入医疗设备
公开(公告)号：WO2010062988A3
公开(公告)日：2010-08-05
申请号：PCT/US2009065979
申请日：2009-11-25
申请人： MEDTRONIC INC , GADAGKAR HRISHIKESH , ZIMMERMAN JAMES , OLSEN JAMES M , JAGLER ROBYN L , ABRAHAM TIMOTHY R , DIXON JEFFREY R
发明人： GADAGKAR HRISHIKESH , ZIMMERMAN JAMES , OLSEN JAMES M , JAGLER ROBYN L , ABRAHAM TIMOTHY R , DIXON JEFFREY R
IPC分类号： A61N1/36 , A61B5/055 , A61N1/08 , A61N1/37 , A61N1/372 , G06F19/00
CPC分类号： A61N1/37264 , A61B5/055 , A61N1/086 , A61N1/3718 , A61N1/372 , A61N1/37247 , A61N1/37258 , A61N1/37282 , A61N1/3925 , G01R33/285 , G01R33/288 , G16H40/40
摘要： A system may include an active implantable medical device implantable in a body of a patient and a patient programmer for the AIMD. The patient programmer may be configured to obtain magnetic resonance imaging (MRI) compatibility information regarding compatibility of the AIMD with an MRI modality.
摘要翻译：系统可以包括可植入患者体内的有源可植入医疗设备和用于AIMD的患者编程器。患者编程器可以被配置为获得关于AIMD与MRI模式的兼容性的磁共振成像（MRI）兼容性信息。

5. 发明申请

WO2010062984A3 PATIENT-CENTRIC DATA COLLECTION FOR AUTOMATED MRI COMPATIBILITY VERIFICATION 审中-公开
标题翻译：患者中心数据采集自动MRI兼容性验证
公开(公告)号：WO2010062984A3
公开(公告)日：2010-10-14
申请号：PCT/US2009065974
申请日：2009-11-25
申请人： MEDTRONIC INC , GADAGKAR HRISHIKESH , ZIMMERMAN JAMES , OLSEN JAMES M , JAGLER ROBYN L , ABRAHAM TIMOTHY R , DIXON JEFFREY R
发明人： GADAGKAR HRISHIKESH , ZIMMERMAN JAMES , OLSEN JAMES M , JAGLER ROBYN L , ABRAHAM TIMOTHY R , DIXON JEFFREY R
IPC分类号： G06F19/00 , A61B5/055 , A61N1/08 , A61N1/36 , A61N1/37 , A61N1/372
CPC分类号： A61N1/37264 , A61B5/055 , A61N1/086 , A61N1/3718 , A61N1/372 , A61N1/37247 , A61N1/37258 , A61N1/37282 , A61N1/3925 , G01R33/285 , G01R33/288 , G16H40/40
摘要： A system may include a patient information terminal that receives magnetic resonance imaging compatibility information from a patient and a processor that automatically determines compatibility of an active implantable medical device with an magnetic resonance imaging modality based on the magnetic resonance imaging compatibility information. The magnetic resonance imaging compatibility information includes information relating to compatibility of the active implantable medical device implantable in the patient and the magnetic resonance imaging modality.
摘要翻译：系统可以包括从患者和处理器接收磁共振成像兼容性信息的患者信息终端，所述处理器基于磁共振成像兼容性信息自动确定有源可植入医疗装置与磁共振成像模态的兼容性。磁共振成像兼容性信息包括与可植入患者的有源可植入医疗装置与磁共振成像模式的兼容性有关的信息。

6. 发明申请

WO2010062978A3 AUTOMATED VERIFICATION OF MRI COMPATIBILITY OF ACTIVE IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：自动验证活动可植入医疗器械的MRI兼容性
公开(公告)号：WO2010062978A3
公开(公告)日：2010-08-12
申请号：PCT/US2009065964
申请日：2009-11-25
申请人： MEDTRONIC INC , GADAGKAR HRISHIKESH , ZIMMERMAN JAMES , OLSEN JAMES M , JAGLER ROBYN L , ABRAHAM TIMOTHY R , DIXON JEFFREY R
发明人： GADAGKAR HRISHIKESH , ZIMMERMAN JAMES , OLSEN JAMES M , JAGLER ROBYN L , ABRAHAM TIMOTHY R , DIXON JEFFREY R
IPC分类号： G06F19/00 , A61B5/055 , A61N1/08 , A61N1/36 , A61N1/37 , A61N1/372
CPC分类号： A61N1/37264 , A61B5/055 , A61N1/086 , A61N1/3718 , A61N1/372 , A61N1/37247 , A61N1/37258 , A61N1/37282 , A61N1/3925 , G01R33/285 , G01R33/288 , G16H40/40
摘要： A system may include a processor configured to automatically obtain magnetic resonance imaging compatibility information relating to compatibility of an active implantable medical device implantable in a patient with an MRI modality from at least two information sources. The processor may also be configured to automatically determine compatibility of the active implantable medical device with the magnetic resonance imaging modality based on the magnetic resonance imaging compatibility information.
摘要翻译：系统可以包括处理器，其被配置为自动获得与可植入患者的有源可植入医疗装置与来自至少两个信息源的MRI模态的兼容性相关的磁共振成像兼容性信息。处理器还可以被配置为基于磁共振成像兼容性信息自动确定主动植入式医疗装置与磁共振成像模态的兼容性。

7. 发明申请

WO2005102444A3 MRI-SAFE IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译： MRI-SAFE可植入医疗器械
公开(公告)号：WO2005102444A3
公开(公告)日：2007-06-07
申请号：PCT/US2004040082
申请日：2004-11-30
申请人： MEDTRONIC INC , WAHLSTRAND CARL D , SKIME ROBERT M , HRDLICKA GREGORY A , OLSEN JAMES M , BOLEA STEPHEN L
发明人： WAHLSTRAND CARL D , SKIME ROBERT M , HRDLICKA GREGORY A , OLSEN JAMES M , BOLEA STEPHEN L
IPC分类号： A61N1/36 , A61N1/05 , A61N1/34 , A61N1/375
CPC分类号： A61N1/08 , A61N1/05 , A61N1/0534 , A61N1/0551 , A61N1/086 , A61N1/36071
摘要： A medical lead is provided for use in a pulse stimulation system of the type which includes a pulse generator (102) for producing electrical stimulation therapy. The lead comprises an elongate insulating body (120) and at least one electrical conductor (106) within the insulating body (120). The conductor has a proximal end configured to be electrically coupled to the pulse generator and has a DC resistance in the range of 375-2000 ohms. At least one distal electrode (114) is coupled to the conductor (106).
摘要翻译：提供了一种用于包括用于产生电刺激疗法的脉冲发生器（102）的脉冲刺激系统的医疗引线。引线包括细长绝缘体（120）和绝缘体（120）内的至少一个电导体（106）。导体具有被配置为电耦合到脉冲发生器的近端，并具有在375-2000欧姆范围内的直流电阻。至少一个远端电极（114）耦合到导体（106）。

8. 发明申请

WO2005120605A3 FLOW REGULATOR 审中-公开
标题翻译：流量调节器
公开(公告)号：WO2005120605A3
公开(公告)日：2006-04-20
申请号：PCT/US2005020062
申请日：2005-06-07
申请人： MEDTRONIC INC , OLSEN JAMES M
发明人： OLSEN JAMES M
IPC分类号： A61K9/00 , A61K9/22 , A61M5/142 , A61M5/168
CPC分类号： A61K9/0024 , A61M5/14276 , A61M5/16881
摘要： A flow regulator (19, 208, 308, 408) may be used in a drug delivery system (10). The regulator includes a chamber that is divided by a diaphragm (111, 211, 311, 411) into a first and second subchamber. A third subchamber is in fluid communication with the first subchamber. A valve (26, 217, 317, 417) is operatively connected to the diaphragm, wherein pressure differences between the first subchamber and second subchamber result in movement of the diaphragm and movement of the diaphragm controls operation of the valve. A flow restrictor (116, 216, 316, 416) is in fluid communication between the first and second subchambers. Flow of a drug (11, 101) is thereby regulated.
摘要翻译：流量调节器（19,208,308,408）可以用在药物递送系统（10）中。调节器包括由隔膜（111,211,311,411）分成第一和第二子室的腔室。第三个子室与第一个子室流体连通。阀（26,217,317,417）可操作地连接到隔膜，其中第一子室和第二子室之间的压力差导致隔膜的运动并且隔膜的运动控制阀的操作。限流器（116,216,316,416）在第一和第二子室之间流体连通。由此调节药物（11,101）的流动。

9. 发明申请

WO2005120605A8 FLOW REGULATOR 审中-公开
标题翻译：流量调节器
公开(公告)号：WO2005120605A8
公开(公告)日：2007-03-22
申请号：PCT/US2005020062
申请日：2005-06-07
申请人： MEDTRONIC INC , OLSEN JAMES M
发明人： OLSEN JAMES M
IPC分类号： A61M5/142 , A61K9/00 , A61K9/22 , A61M5/168
CPC分类号： A61K9/0024 , A61M5/14276 , A61M5/16881
摘要： A flow regulator (19, 208, 308, 408) may be used in a drug delivery system (10). The regulator includes a chamber that is divided by a diaphragm (111, 211, 311, 411) into a first and second subchamber. A third subchamber is in fluid communication with the first subchamber. A valve (26, 217, 317, 417) is operatively connected to the diaphragm, wherein pressure differences between the first subchamber and second subchamber result in movement of the diaphragm and movement of the diaphragm controls operation of the valve. A flow restrictor (116, 216, 316, 416) is in fluid communication between the first and second subchambers. Flow of a drug (11, 101) is thereby regulated.
摘要翻译：流量调节器（19,208,308,408）可以用在药物递送系统（10）中。调节器包括由隔膜（111,211,311,411）分成第一和第二子室的腔室。第三个子室与第一个子室流体连通。阀（26,217,317,417）可操作地连接到隔膜，其中第一子室和第二子室之间的压力差导致隔膜的运动并且隔膜的运动控制阀的操作。限流器（116,216,316,416）在第一和第二子室之间流体连通。由此调节药物（11,101）的流动。

10. 发明申请

WO2006093686A3 LEAD ELECTRODE FOR USE IN AN MRI-SAFE IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：铅电极用于MRI安全植入式医疗设备
公开(公告)号：WO2006093686A3
公开(公告)日：2006-11-30
申请号：PCT/US2006005539
申请日：2006-02-15
申请人： MEDTRONIC INC , PRZYBYSZEWSKI PIOTR , WAHLSTRAND CARL A , DAVIS TIMOTHY J , HRDLICKA GREGORY A , OLSEN JAMES M
发明人： PRZYBYSZEWSKI PIOTR , WAHLSTRAND CARL A , DAVIS TIMOTHY J , HRDLICKA GREGORY A , OLSEN JAMES M
IPC分类号： A61N1/08 , A61N1/05 , A61N1/16 , A61N1/18 , A61N1/34 , A61N1/37 , A61N1/375 , G01R27/16
CPC分类号： A61N1/0551 , A61N1/0534 , A61N1/08 , A61N1/086 , A61N1/3605 , A61N1/36071 , A61N1/36125 , A61N1/36142 , A61N1/3718 , A61N2001/086
摘要： An implantable stimulation system comprises a stimulator (138) for generating electrical stimulation and a conductive stimulation lead (134) having a proximal end electrically coupled to the stimulator (138), wherein at least a first component of the impedance looking into the stimulator (138) is substantially matched to the impedance of the stimulation lead (134). At least one distal stimulation electrode (132) is positioned proximate the distal end of the stimulation lead (134).
摘要翻译：一种可植入刺激系统包括用于产生电刺激的刺激器（138）和具有电耦合到刺激器（138）的近端的导电刺激引线（134），其中阻抗的至少第一分量看向刺激器（138 ）基本上与刺激引线（134）的阻抗匹配。至少一个远端刺激电极（132）位于刺激引线（134）的远端附近。

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