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1. 发明申请

WO2007140331A2 METHODS OF USING HIGH INTENSITY FOCUSED ULTRASOUND TO FORM AN ABLATED TISSUE AREA CONTAINING A PLURALITY OF LESIONS 审中-公开
标题翻译：使用高强度聚焦超声波形成包含多种淋巴结的组织组织的方法
公开(公告)号：WO2007140331A2
公开(公告)日：2007-12-06
申请号：PCT/US2007/069789
申请日：2007-05-25
申请人： MEDTRONIC, INC. , STEWART, Mark, T. , FRANCISCHELLI, David, E. , KEOGH, James, R. , HISSONG, James, B. , SKARDA, James, R. , LEE, Hotaik , SMITH, Nadine, B.
发明人： STEWART, Mark, T. , FRANCISCHELLI, David, E. , KEOGH, James, R. , HISSONG, James, B. , SKARDA, James, R. , LEE, Hotaik , SMITH, Nadine, B.
IPC分类号： A61N7/02
CPC分类号： A61B17/320068 , A61B8/4281 , A61B34/20 , A61B2017/320076 , A61B2017/320078 , A61B2018/00291 , A61B2034/2051 , A61B2090/378 , A61B2090/3782 , A61N7/02 , A61N7/022 , A61N2007/0078
摘要： A device and method for ablating tissue is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding an ablating member within the patient while tracking the position of the ablating member in the patient, positioning the ablating member in a desired position to ablate tissue, emitting ablating energy from the ablating member to form an ablated tissue area and removing the ablating member from the patient.
摘要翻译：公开了一种用于消融组织的装置和方法，包括以下步骤：获取患者的解剖图像，将图像与患者相关联，在跟踪患者内的消融部件的位置的同时引导患者内的消融部件，定位消融成员在消融组织的期望位置，从烧蚀构件发出消融能量以形成消融的组织区域，并从患者身上移除消融部件。

2. 发明申请

WO2005113068A1 METHODS OF USING HIGH INTENSITY FOCUSED ULTRASOUND TO FORM AN ABLATED TISSUE AREA 审中-公开
标题翻译：使用高强度聚焦超声波形成组织组织的方法
公开(公告)号：WO2005113068A1
公开(公告)日：2005-12-01
申请号：PCT/US2005/016860
申请日：2005-05-13
申请人： MEDTRONIC, INC. , STEWART, Mark, T. , FRANCISCHELLI, David, E. , SKARDA, James, R. , KEOGH, James, R. , HISSONG, James, B.
发明人： STEWART, Mark, T. , FRANCISCHELLI, David, E. , SKARDA, James, R. , KEOGH, James, R. , HISSONG, James, B.
IPC分类号： A61N7/02
CPC分类号： A61N7/022 , A61B8/4281 , A61B17/2202 , A61B18/1492 , A61B2018/00291 , A61B2018/00351 , A61B2018/00357 , A61B2018/00363 , A61B2018/00839 , A61B2018/1472
摘要： A method of thermal ablation using high intensity focused ultrasound energy includes the steps of positioning one or more ultrasound emitting members within a patient, emitting ultrasound energy from the one or more ultrasound emitting members, focusing the ultrasound energy, ablating with the focused ultrasound energy to form an ablated tissue area and removing the ultrasound emitting member.
摘要翻译：使用高强度聚焦超声能量的热消融的方法包括将一个或多个超声发射部件定位在患者体内的步骤，从一个或多个超声发射部件发射超声能量，将超声能量聚焦，用聚焦的超声能量消融到形成消融的组织区域并移除超声发射构件。

3. 发明申请

WO2007067945A2 METHOD FOR GUIDING A MEDICAL DEVICE 审中-公开
标题翻译：用于引导医疗装置的方法
公开(公告)号：WO2007067945A2
公开(公告)日：2007-06-14
申请号：PCT/US2006/061722
申请日：2006-12-07
申请人： MEDTRONIC, INC , FRANCISCHELLI, David, E , HISSONG, James, B. , KEOGH, James, R. , SKARDA, James, R. , STEWART, Mark, T.
发明人： FRANCISCHELLI, David, E , HISSONG, James, B. , KEOGH, James, R. , SKARDA, James, R. , STEWART, Mark, T.
CPC分类号： A61N7/02 , A61B8/4272 , A61B18/1442 , A61B34/20 , A61B2017/00243 , A61B2018/00291 , A61B2034/2051 , A61B2034/2053 , A61B2034/2063 , A61B2090/378 , A61B2090/397 , A61N7/022 , A61N2007/0078

5. 发明申请

WO2005112812A1 METHOD AND DEVICES FOR TREATING ATRIAL FIBRILLATION BY MASS ABLATION 审中-公开
标题翻译：用于通过大规模消除治疗心律失常的方法和装置
公开(公告)号：WO2005112812A1
公开(公告)日：2005-12-01
申请号：PCT/US2005/016806
申请日：2005-05-13
申请人： MEDTRONIC, INC. , STEWART, Mark, T. , FRANCISCHELLI, David, E. , SKARDA, James, R.
发明人： STEWART, Mark, T. , FRANCISCHELLI, David, E. , SKARDA, James, R.
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B17/2202 , A61B18/02 , A61B18/04 , A61B18/06 , A61B18/149 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B18/20 , A61B2018/0022 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00351 , A61B2018/00357 , A61B2018/00363 , A61B2018/00577 , A61B2018/00839 , A61B2018/00982 , A61B2018/0212 , A61B2018/1405 , A61B2018/1472 , A61B2018/1861 , A61M5/14 , A61N7/022
摘要： Apparatus and method for ablating target tissue including a non-linear area of tissue in the left atrium of a patient. The method can include selecting an ablation apparatus having an ablator with a tissue engagement section, penetrating a chest cavity of the patient, and identifying the target tissue. The method can also include positioning the ablation apparatus adjacent to the target tissue so that the tissue engagement section can transfer ablation energy to the target tissue. The method can further include energizing the tissue engagement section with ablation energy in order to create a footprint on the non-linear area of tissue in the left atrium and to reduce an overall mass of excitable tissue in the left atrium.
摘要翻译：用于消融包括患者左心房中组织的非线性区域的靶组织的装置和方法。该方法可以包括选择具有消融器的消融装置，其具有组织接合部分，穿透患者的胸腔，并且识别目标组织。该方法还可以包括将消融设备定位成邻近目标组织，使得组织接合部分可以将消融能量传递到目标组织。该方法还可以包括用消融能激发组织接合部分，以便在左心房的组织的非线性区域上产生足迹并且减小左心房中的可兴奋组织的整体质量。

6. 发明公开

EP1583577A2 STEERABLE CATHETER 有权
标题翻译：可操纵导管
公开(公告)号：EP1583577A2
公开(公告)日：2005-10-12
申请号：EP03800020.4
申请日：2003-12-19
申请人： MEDTRONIC, INC.
发明人： WALDHAUSER, Steven, L. , GESKE, Jeff , TEISANU, Eduard, T. , SKARDA, James, R. , SHIPE, Gregory, P.
IPC分类号： A61M25/00
CPC分类号： A61M25/0012 , A61M25/0029 , A61M25/005 , A61M25/0053 , A61M25/0054 , A61M25/0147 , A61M2025/0034 , A61M2025/0037 , A61M2025/0177 , A61M2025/018
摘要： A steerable catheter and methods of fabrication including a catheter body (12) formed of a continuous wire braid formed of wires braided over a delivery lumen (24) liner and a pull wire lumen (26) liner distal to a pull wire jacket port (32), braided around the pull wire jacket port to form a braid port (90), and over at least a portion of the delivery lumen liner proximal to the pull wire jacket port. A pull wire (30) extends from a pull wire proximal end through the pull wire lumen port and through the pull wire lumen to a pull wire distal end. A band is attached to the pull wire distal end and fitted over a distal segment of the wire braid proximal to the catheter body distal end to fix the pull wire distal end to the catheter body.

7. 发明申请

WO2004058341A3 STEERABLE CATHETER 审中-公开
公开(公告)号：WO2004058341A3
公开(公告)日：2004-07-15
申请号：PCT/US2003/040635
申请日：2003-12-19
申请人： MEDTRONIC, INC.
发明人： WALDHAUSER, Steven, L. , GESKE, Jeff , TEISANU, Eduard, T. , SKARDA, James, R. , SHIPE, Gregory, P.
IPC分类号： A61M25/01 , A61M25/00
摘要： A steerable catheter and methods of fabrication including a catheter body (12) formed of a continuous wire braid formed of wires braided over a delivery lumen (24) liner and a pull wire lumen (26) liner distal to a pull wire jacket port (32), braided around the pull wire jacket port to form a braid port (90), and over at least a portion of the delivery lumen liner proximal to the pull wire jacket port. A pull wire (30) extends from a pull wire proximal end through the pull wire lumen port and through the pull wire lumen to a pull wire distal end. A band is attached to the pull wire distal end and fitted over a distal segment of the wire braid proximal to the catheter body distal end to fix the pull wire distal end to the catheter body.

8. 发明申请

WO2004033013A1 POROUS MEDICAL CATHETER AND METHODS OF MANUFACTURE 审中-公开
标题翻译：多孔医用导管及其制造方法
公开(公告)号：WO2004033013A1
公开(公告)日：2004-04-22
申请号：PCT/US2003/031339
申请日：2003-10-02
申请人： MEDTRONIC, INC.
发明人： VETTLING, Patrick, R. , STEWART, Mark, T. , SKARDA, James, R.
IPC分类号： A61M25/00
CPC分类号： B29C65/68 , A61B18/1492 , A61B2017/00044 , A61B2017/00243 , A61B2017/00867 , A61B2018/00065 , A61B2018/00214 , A61B2018/00375 , A61B2018/00404 , A61B2018/00898 , A61B2018/1407 , A61B2018/1435 , A61B2018/1472 , A61L29/041 , A61L29/06 , A61L29/146 , A61M25/0009 , B29C61/006 , B29C65/4815 , B29C65/483 , B29C65/484 , B29C65/4845 , B29C66/026 , B29C66/1122 , B29C66/1222 , B29C66/1224 , B29C66/12445 , B29C66/5221 , B29C66/52291 , B29C66/52293 , B29C66/63 , B29C66/636 , B29C66/71 , B29C66/727 , B29K2027/18 , B29L2023/007 , B29L2031/7542 , C08L27/18 , B29K2083/00 , B29K2081/06 , B29K2077/00 , B29K2075/00 , B29K2023/18 , B29K2023/12 , B29K2023/06 , B29K2019/00 , C08L77/12
摘要： The present invention relates to fabrication methods and apparatus for irrigating medical catheters. Such catheters include at least one section of standard thermoplastic catheter tubing coupled to a section of porous tubing (e.g., ePTFE and the like). A source of fluid couples to the porous portion of tubing to dispense diverse fluids. The manufacturing technique overcomes the inability of such porous material to liquefy and/or bond to most available adhesives by creating a mechanical-based coupling. One aspect of the present invention involves pre-treatment of a portion of a porous material such as ePTFE; that is, a "pre-imbibing" process is employed wherein the ePTFE is saturated with a solution of solvent and dissolved thermoplastic resin. After the solution evaporates a resin-based interstitial residue provides suitable structure that fuses to adjacent thermoplastic material during application of heat, such as during thermal bonding. The present may be used to prepare virtually any porous material for thermoplastic bonding.
摘要翻译：本发明涉及用于冲洗医用导管的制造方法和装置。这种导管包括与多孔管（例如，ePTFE等）的一部分连接的标准热塑性导管的至少一部分。流体源耦合到管道的多孔部分以分配多种流体。该制造技术克服了这种多孔材料不能通过创建基于机械的耦合来液化和/或粘合到大多数可用的粘合剂。本发明的一个方面涉及一部分多孔材料的预处理，例如ePTFE; 也就是说，使用其中ePTFE被溶剂和溶解的热塑性树脂溶液饱和的“预吸收”方法。溶液蒸发后，树脂基间隙残渣提供了适合的结构，其在加热期间例如在热粘合期间在相邻的热塑性材料上熔化。本发明可用于制备用于热塑性粘合的几乎任何多孔材料。

9. 发明申请

WO2002102263A1 RADIOFREQUENCY ABLATION SYSTEM AND METHOD OF USE 审中-公开
标题翻译：射频消融系统及其使用方法
公开(公告)号：WO2002102263A1
公开(公告)日：2002-12-27
申请号：PCT/US2002/013179
申请日：2002-04-25
申请人： MEDTRONIC, INC.
发明人： FRANCISCHELLI, David, E. , MEHRA, Rahul , SKARDA, James, R. , SCHWARTZMAN, David , WARMAN, Eduardo, N. , STEWART, Mark, T. , PURYEAR, Harry, A.
IPC分类号： A61B18/14
CPC分类号： A61B18/1445 , A61B5/04 , A61B18/12 , A61B2018/00065 , A61B2018/00363 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00755 , A61B2018/00779 , A61B2018/00791 , A61B2018/00839 , A61B2018/00875 , A61B2018/1226 , A61B2018/1253 , A61B2018/126 , A61B2018/1467 , A61B2018/1472 , A61B2218/002 , A61N1/403
摘要： A system and method for creating lesions and assessing their completeness or transmurality. Assessment of transmurality of a lesion is accomplished by monitoring the depolarization signal amplitude in a local electrogram taken using electrodes located adjacent the tissue to be ablated. Following onset of application of ablation energy to heart tissue, the amplitude of a local electrogram measured with electrodes located adjacent tissue to be ablated first gradually drops and then stabilizes, indicating that the tissue being monitored has ceased making any contribution to the sensed electrogram. The amplitude drop and/or the following amplitude plateau may be used alone or together as indicators of transmurality. Detection of a rapid drop in amplitude may be employed as an indicator that the ablation process is proceeding too quickly and may be employed to trigger a reduction in the power of applied ablation energy. Detection of an insufficiently rapid drop in amplitude may be employed as an indicator that the ablation process is proceeding too slowly and may be employed to trigger an increase in the power of applied ablation energy.
摘要翻译：用于创建病变并评估其完整性或透视性的系统和方法。病变透壁度的评估是通过在使用邻近待消融组织的电极拍摄的局部电描记图中监测去极化信号振幅来实现的。在开始将消融能量施加到心脏组织之后，首先用邻近要消融的组织的电极测量的局部电描记图的幅度逐渐下降然后稳定，表明所监测的组织已停止对感测的电描记图作出任何贡献。幅度下降和/或随后的振幅平台可以单独使用或一起用作透壁度的指标。振幅的快速下降的检测可以用作消融过程进展得太快的指标，并且可以用于触发施加的消融能量的功率的降低。可以采用振幅不充分快速下降的检测作为消融过程进行得太慢的指标，并且可以用于触发施加的消融能量的功率的增加。

10. 发明申请

WO2002094334A1 MALLEABLE ELONGATED MEDICAL DEVICE 审中-公开
标题翻译：可弹性伸长的医疗装置
公开(公告)号：WO2002094334A1
公开(公告)日：2002-11-28
申请号：PCT/US2002/016136
申请日：2002-05-21
申请人： MEDTRONIC, INC.
发明人： SKARDA, James, R.
IPC分类号： A61L31/02
CPC分类号： A61M25/0041 , A61B18/1492 , A61B2018/00386 , A61L29/02 , A61L31/022 , A61M25/0068 , A61M25/0069 , A61M25/008 , A61M25/0082 , A61M25/09 , A61M2025/0063 , A61M2025/09141 , A61M2205/0266 , C22C14/00
摘要： An elongated medical device insertable through an access pathway into a body vessel, organ or cavity to locate a therapeutic or diagnostic distal segment of the elongated medical device into alignment with an anatomic feature of interest having a malleable distal segment capable of being manually formed into a shape facilitating such alignment at room temperature. The elongated medical device includes a device body distal section formed of a malleable material including an elongated, malleable member disposed on or within the device body extending in the direction of the device body axis. The malleable member is formed of a Beta III titanium alloy of the type exhibiting superelastic properties when subjected to strain at a bending strain of less than a set threshold strain and capable of undergoing plastic flow to take a set shape when subjected to a strain of greater than the set threshold at the same temperature.
摘要翻译：细长的医疗装置可以通过进入通道插入身体容器，器官或空腔中，以将细长的医疗装置的治疗或诊断远侧段定位成与感兴趣的解剖特征对准，具有可延展的远端段，其能够手动形成为形状有助于在室温下进行这种对准。细长的医疗装置包括由可延展材料形成的装置主体远端部分，其包括设置在装置本体上或装置本体轴线方向上延伸的细长的可延展部件。该韧性构件由具有超弹性特性的βIII型钛合金形成，当经受小于设定阈值应变的弯曲应变下的应变时，当受到较大应变时，能够经受塑性流动以形成一定形状在相同温度下的设定阈值。

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