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1. 发明申请

WO2012103000A1 DE-AIRING OXYGENATOR FOR TREATING BLOOD IN AN EXTRACORPOREAL BLOOD CIRCUIT 审中-公开
标题翻译：用于在血液中检测血液的空气氧化剂
公开(公告)号：WO2012103000A1
公开(公告)日：2012-08-02
申请号：PCT/US2012/022199
申请日：2012-01-23
申请人： MEDTRONIC INC. , CLOUTIER, Patrick , OLSEN, Robert , ROLLER, Stephen , PLOTT, Chris , MCLEVISH, Al , LI, Ming , LAXEN, Michael , KNOLL, John , HAKE, Gregory
发明人： CLOUTIER, Patrick , OLSEN, Robert , ROLLER, Stephen , PLOTT, Chris , MCLEVISH, Al , LI, Ming , LAXEN, Michael , KNOLL, John , HAKE, Gregory
IPC分类号： A61M1/16
CPC分类号： A61M1/1698 , A61M2206/16 , A61M2206/20
摘要： An apparatus (20) for de-aering, oxygenating and controlling a temperature of blood in an extracorporeal blood circuit. The apparatus includes a housing (22), a manifold body (24), a heat exchanger (26), and an oxygenator (28). A blood inlet (32) tangentially directs blood into a first chamber of the housing. The manifold body is disposed in a second chamber, and includes a core (100) and a plurality of vanes (102) that define channels. The heat exchanger is arranged around the manifold body, and the oxygenator around the heat exchanger. The channels are open to the heat exchanger. An established blood flow path includes rotational flow within the first chamber to separate air from the blood, generally longitudinal flow from the first chamber and along the channels, and generally radial flow through the heat exchanger and the oxygenator. With this construction, gross air removal occurs prior to the blood passing through the heat exchanger and oxygenator.
摘要翻译：一种用于在体外血液回路中去除，氧合和控制血液温度的装置（20）。该装置包括壳体（22），歧管主体（24），热交换器（26）和氧合器（28）。血液入口（32）切向地将血液引导到壳体的第一腔室中。歧管主体设置在第二室中，并且包括限定通道的芯（100）和多个叶片（102）。热交换器布置在歧管主体周围，并且热交换器周围设置有氧合器。通道通向热交换器。已建立的血流路径包括在第一室内的旋转流动，以从血液中分离空气，大体上来自第一腔室的纵向流动并且沿着通道，并且通常径向流过热交换器和氧合器。利用这种结构，在血液通过热交换器和充氧器之前，总的空气除去发生。

2. 发明申请

WO2013122749A1 DUAL OUTLET OXYGENATOR FOR TREATING BLOOD IN AN EXTRACORPOREAL BLOOD CIRCUIT 审中-公开
标题翻译：用于在血液中检测血液的双出口氧化剂
公开(公告)号：WO2013122749A1
公开(公告)日：2013-08-22
申请号：PCT/US2013/024051
申请日：2013-01-31
申请人： MEDTRONIC INC.
发明人： ROLLER, Stephen , PLOTT, Christopher , MCLEVISH, Alford , HAKE, Gregory , STEFFENS, Brian
IPC分类号： A61M1/16
CPC分类号： A61M1/1698 , A61M1/36 , A61M2209/082
摘要： An apparatus (20) for oxygenating blood including a housing (22) and an oxygenator bundle. The housing defines a primary chamber, a blood inlet port (32) open to the primary chamber, and a blood outlet region. The outlet region includes a blood outlet port (34), an outlet chamber open to the outlet port, and a partition. The partition establishes spaced apart, first and second passageways from the primary chamber to the outlet chamber. The oxygenator bundle is disposed within the primary chamber. A blood flow path is formed from the blood inlet port, through the oxygenator bundle and to the blood outlet port, and includes first and second outlet flow paths within the outlet chamber via the first and second passageways, respectively. The first and second outlet blood flow paths merge at the blood outlet port. A dual port blood outlet is created, increasing mixing of blood immediately upstream of the outlet port.
摘要翻译：一种用于使血液充氧的装置（20），包括壳体（22）和充氧器束。壳体限定主室，通向主室的血液入口（32）和血液出口区域。出口区域包括血液出口（34），通向出口的出口腔和分隔件。分隔件形成从主室到出口室的间隔开的第一和第二通道。充氧器束设置在主室内。血液流路由血液入口通过充氧器束和血液出口形成，并且分别经由第一和第二通道包括出口室内的第一和第二出口流动路径。第一和第二出血血流通道在血液出口处合并。产生双口血液出口，增加了紧靠出口端上游的血液混合。

3. 发明申请

WO2021061908A1 PROSTHESIS WITH ANTI-PARAVALVULAR LEAKAGE COMPONENT INCLUDING A ONE-WAY VALVE 审中-公开
公开(公告)号：WO2021061908A1
公开(公告)日：2021-04-01
申请号：PCT/US2020/052388
申请日：2020-09-24
申请人： MEDTRONIC, INC.
发明人： CLAGUE, Cynthia , MENK, Ana , PETERSEN, Tim , ROTHSTEIN, Paul , ROLLER, Stephen
IPC分类号： A61F2/24
摘要： A transcatheter prosthesis includes a stent, a prosthetic valve component, and an anti-paravalvular leakage component. The anti-paravalvular leakage component is coupled to the stent and includes an inner skirt, an outer wrap, a cavity, an opening, and a one-way valve. The inner skirt is disposed on an inner surface of the stent and has an inflow end and a downstream end. The outer wrap is disposed around an outer surface of the stent and has an inflow end coupled to the inflow end of the inner skirt and a downstream end. The cavity is formed between an outer surface of the inner skirt and an inner surface of the outer wrap. An opening is disposed between the inner skirt and the outer wrap. The one-way valve includes a flap at the opening configured to open to allow blood flow into the cavity but prevent blood flow out of the cavity.

4. 发明申请

WO2012103001A1 WOUND HEAT EXCHANGER 审中-公开
标题翻译：热交换器
公开(公告)号：WO2012103001A1
公开(公告)日：2012-08-02
申请号：PCT/US2012/022200
申请日：2012-01-23
申请人： MEDTRONIC INC. , CLOUTIER, Patrick , OLSEN, Robert , ROLLER, Stephen , PLOTT, Chris , MCLEVISH, Al , LI, Ming , LAXEN, Michael , KNOLL, John , HAKE, Gregory
发明人： CLOUTIER, Patrick , OLSEN, Robert , ROLLER, Stephen , PLOTT, Chris , MCLEVISH, Al , LI, Ming , LAXEN, Michael , KNOLL, John , HAKE, Gregory
IPC分类号： A61M1/16 , A61M1/36 , B01D63/02 , B29C53/66
CPC分类号： F28D15/046 , A61M1/1698 , A61M1/367 , A61M1/369 , B01D63/025 , B01D2313/38 , B29C53/083 , B29L2031/18 , Y10T29/49353
摘要： A capillary tube bundle sub -assembly for use in an extracorporeal heat exchanger includes a continuous capillary tubing (22) wound about a core (24) to define a plurality of capillary layers each including a plurality of capillary segments. The capillary segments each define opposing terminal ends adjacent opposing ends of the core. The capillary segments of each layer are circumferentially aligned relative to an axis of the core, with each successive layer being radially outward of an immediately preceding layer. The capillary segments are non-parallel with the axis, spiraling partially about the axis in extension between the opposing terminal ends. Each capillary segment forms less than one complete revolution (i.e., winds less than 360°). The segments within each layer are substantially parallel with one another; however, an orientation of the segments differs from layer- to- layer such as by pitch or angle.
摘要翻译：用于体外热交换器的毛细管束子组件包括围绕芯部（24）缠绕以限定多个毛细管层的连续毛细管（22），每个毛细管层包括多个毛细管段。毛细管段各自限定与芯的相对端相邻的相对的末端。每个层的毛细管段相对于芯的轴线周向对准，每个连续层在紧邻的前一层的径向外侧。毛细管段与轴不平行，部分地围绕相对端部之间延伸的轴线螺旋形。每个毛细管段形成少于一个完整的旋转（即，风小于360°）。每个层内的段基本上彼此平行; 然而，片段的取向与层间不同，例如通过间距或角度。

5. 发明公开

EP2667909A1 WOUND HEAT EXCHANGER 有权
标题翻译：缠绕式换热交换
公开(公告)号：EP2667909A1
公开(公告)日：2013-12-04
申请号：EP12704953.4
申请日：2012-01-23
申请人： Medtronic, Inc. , Laxen, Michael
发明人： LAXEN, Michael , CLOUTIER, Patrick , OLSEN, Robert , ROLLER, Stephen , PLOTT, Chris , MCLEVISH, Al , LI, Ming , KNOLL, John , HAKE, Gregory
IPC分类号： A61M1/16 , A61M1/36 , B01D63/02 , B29C53/66
CPC分类号： F28D15/046 , A61M1/1698 , A61M1/367 , A61M1/369 , B01D63/025 , B01D2313/38 , B29C53/083 , B29L2031/18 , Y10T29/49353
摘要： A capillary tube bundle sub-assembly for use in an extracorporeal heat exchanger includes a continuous capillary tubing wound about a core to define a plurality of capillary layers each including a plurality of capillary segments. The capillary segments each define opposing terminal ends adjacent opposing ends of the core. The capillary segments of each layer are circumferentially aligned relative to an axis of the core, with each successive layer being radially outward of an immediately preceding layer. The capillary segments are non-parallel with the axis, spiraling partially about the axis in extension between the opposing terminal ends. Each capillary segment forms less than one complete revolution (i.e., winds less than 360°). The segments within each layer are substantially parallel with one another; however, an orientation of the segments differs from layer-to-layer such as by pitch or angle.

6. 发明公开

EP2814536A1 DUAL OUTLET OXYGENATOR FOR TREATING BLOOD IN AN EXTRACORPOREAL BLOOD CIRCUIT 有权
标题翻译：用于血液处理氧合双输出。在血液张福亭
公开(公告)号：EP2814536A1
公开(公告)日：2014-12-24
申请号：EP13703504.4
申请日：2013-01-31
申请人： Medtronic Inc.
发明人： ROLLER, Stephen , PLOTT, Christopher , MCLEVISH, Alford , HAKE, Gregory , STEFFENS, Brian
IPC分类号： A61M1/16
CPC分类号： A61M1/1698 , A61M1/36 , A61M2209/082
摘要： An apparatus (20) for oxygenating blood including a housing (22) and an oxygenator bundle. The housing defines a primary chamber, a blood inlet port (32) open to the primary chamber, and a blood outlet region. The outlet region includes a blood outlet port (34), an outlet chamber open to the outlet port, and a partition. The partition establishes spaced apart, first and second passageways from the primary chamber to the outlet chamber. The oxygenator bundle is disposed within the primary chamber. A blood flow path is formed from the blood inlet port, through the oxygenator bundle and to the blood outlet port, and includes first and second outlet flow paths within the outlet chamber via the first and second passageways, respectively. The first and second outlet blood flow paths merge at the blood outlet port. A dual port blood outlet is created, increasing mixing of blood immediately upstream of the outlet port.

7. 发明授权

EP2667908B1 DE-AIRING OXYGENATOR FOR TREATING BLOOD IN AN EXTRACORPOREAL BLOOD CIRCUIT 有权
标题翻译： ENTLÜFTUNGSOXYGENATOR用血液的IN A张福亭血流中的治疗
公开(公告)号：EP2667908B1
公开(公告)日：2016-06-29
申请号：EP12702698.7
申请日：2012-01-23
申请人： Medtronic, Inc
发明人： CLOUTIER, Patrick , OLSEN, Robert , ROLLER, Stephen , PLOTT, Chris , MCLEVISH, Al , LI, Ming , LAXEN, Michael , KNOLL, John , HAKE, Gregory
IPC分类号： A61M1/16
CPC分类号： A61M1/1698 , A61M2206/16 , A61M2206/20

8. 发明公开

EP4034040A1 PROSTHESIS WITH ANTI-PARAVALVULAR LEAKAGE COMPONENT INCLUDING A ONE-WAY VALVE 审中-公开
公开(公告)号：EP4034040A1
公开(公告)日：2022-08-03
申请号：EP20786676.5
申请日：2020-09-24
申请人： Medtronic, Inc.
发明人： CLAGUE, Cynthia , MENK, Ana , PETERSEN, Tim , ROTHSTEIN, Paul , ROLLER, Stephen
IPC分类号： A61F2/24

9. 发明授权

EP2814536B1 DUAL OUTLET OXYGENATOR FOR TREATING BLOOD IN AN EXTRACORPOREAL BLOOD CIRCUIT 有权
标题翻译：用于血液处理氧合双输出。在血液张福亭
公开(公告)号：EP2814536B1
公开(公告)日：2016-01-27
申请号：EP13703504.4
申请日：2013-01-31
申请人： Medtronic Inc.
发明人： ROLLER, Stephen , PLOTT, Christopher , MCLEVISH, Alford , HAKE, Gregory , STEFFENS, Brian
IPC分类号： A61M1/36 , A61M1/16
CPC分类号： A61M1/1698 , A61M1/36 , A61M2209/082

10. 发明授权

EP2667909B1 WOUND HEAT EXCHANGER 有权
标题翻译：缠绕式换热交换
公开(公告)号：EP2667909B1
公开(公告)日：2015-12-16
申请号：EP12704953.4
申请日：2012-01-23
申请人： Medtronic, Inc. , Laxen, Michael
发明人： LAXEN, Michael , CLOUTIER, Patrick , OLSEN, Robert , ROLLER, Stephen , PLOTT, Chris , MCLEVISH, Al , LI, Ming , KNOLL, John , HAKE, Gregory
IPC分类号： A61M1/16 , A61M1/36 , B01D63/02 , B29C53/66
CPC分类号： F28D15/046 , A61M1/1698 , A61M1/367 , A61M1/369 , B01D63/025 , B01D2313/38 , B29C53/083 , B29L2031/18 , Y10T29/49353

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