专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20120225793A1 METHODS FOR IDENTIFYING, DIAGNOSING, AND PREDICTING SURVIVAL OF LYMPHOMAS 审中-公开
标题翻译：鉴别，诊断和预测淋巴瘤存活的方法
公开(公告)号：US20120225793A1
公开(公告)日：2012-09-06
申请号：US13409416
申请日：2012-03-01
申请人： Louis M. Staudt , George Wright , Sandeep Dave , Bruce Tan , John I. Powell , Wyndham Wilson , Elaine Jaffe , Wing C. Chan , Timothy C. Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard I. Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia M. Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zetti , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaloy , Harald Holte , Jan Delabie , T. Andrew Lister
发明人： Louis M. Staudt , George Wright , Sandeep Dave , Bruce Tan , John I. Powell , Wyndham Wilson , Elaine Jaffe , Wing C. Chan , Timothy C. Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard I. Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia M. Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zetti , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaloy , Harald Holte , Jan Delabie , T. Andrew Lister
IPC分类号： C40B30/04
CPC分类号： G01N33/6842 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G01N2333/51 , G16B25/00 , G16B40/00 , Y02A90/26
摘要： Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.
摘要翻译：基因表达数据为更准确地鉴定和诊断淋巴组织增生性疾病提供了基础。此外，基因表达数据可用于开发更准确的生存预测因子。本发明公开了基于基因表达模式鉴定，诊断和预测淋巴瘤或淋巴组织增生性疾病存活的方法。本发明公开了一种用于从淋巴瘤样品获得基因表达数据的新型微阵列Lymph Dx微阵列。本发明还公开了多种利用淋巴瘤基因表达数据来确定特定淋巴瘤的身份并预测患有特定淋巴瘤的受试者的存活的方法。该信息将有助于开发与特定受试者一起使用的治疗方法。

2. 发明授权

US08131475B2 Methods for identifying, diagnosing, and predicting survival of lymphomas 有权
标题翻译：识别，诊断和预测淋巴瘤存活的方法
公开(公告)号：US08131475B2
公开(公告)日：2012-03-06
申请号：US11493387
申请日：2006-07-25
申请人： Louis M. Staudt , George Wright , Sandeep Dave , Bruce Tan , John I. Powell , Wyndham Wilson , Elaine Jaffe , Wing C. Chan , Timothy C. Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard I. Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia M Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zettl , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaløy , Harald Holte , Jan Delabie , T. Andrew Lister
发明人： Louis M. Staudt , George Wright , Sandeep Dave , Bruce Tan , John I. Powell , Wyndham Wilson , Elaine Jaffe , Wing C. Chan , Timothy C. Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard I. Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia M Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zettl , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaløy , Harald Holte , Jan Delabie , T. Andrew Lister
IPC分类号： G01N33/48 , C12Q1/68 , G06G7/58
CPC分类号： G01N33/6842 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G01N2333/51 , G06F19/20 , G06F19/24 , Y02A90/26
摘要： Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.
摘要翻译：基因表达数据为更准确地鉴定和诊断淋巴组织增生性疾病提供了基础。此外，基因表达数据可用于开发更准确的生存预测因子。本发明公开了基于基因表达模式鉴定，诊断和预测淋巴瘤或淋巴组织增生性疾病存活的方法。本发明公开了一种用于从淋巴瘤样品获得基因表达数据的新型微阵列Lymph Dx微阵列。本发明还公开了多种利用淋巴瘤基因表达数据来确定特定淋巴瘤的身份并预测患有特定淋巴瘤的受试者的存活的方法。该信息将有助于开发与特定受试者一起使用的治疗方法。

3. 发明授权

US07711492B2 Methods for diagnosing lymphoma types 有权
标题翻译：诊断淋巴瘤类型的方法
公开(公告)号：US07711492B2
公开(公告)日：2010-05-04
申请号：US10934930
申请日：2004-09-03
申请人： Louis M. Staudt , George Wright , Sandeep Dave , Bruce Tan
发明人： Louis M. Staudt , George Wright , Sandeep Dave , Bruce Tan
IPC分类号： G01N33/48 , C12Q1/68 , C12N15/00 , C12N15/11
CPC分类号： G06F19/24 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G06F19/20 , Y02A90/26
摘要： Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.
摘要翻译：基因表达数据为更准确地鉴定和诊断淋巴组织增生性疾病提供了基础。此外，基因表达数据可用于开发更准确的生存预测因子。本发明公开了基于基因表达模式鉴定，诊断和预测淋巴瘤或淋巴组织增生性疾病存活的方法。本发明公开了一种用于从淋巴瘤样品获得基因表达数据的新型微阵列Lymph Dx微阵列。本发明还公开了多种利用淋巴瘤基因表达数据来确定特定淋巴瘤的身份并预测患有特定淋巴瘤的受试者的存活的方法。该信息将有助于开发与特定受试者一起使用的治疗方法。

4. 发明申请

US20050164231A1 Methods for identifying, diagnosing, and predicting survival of lymphomas 有权
标题翻译：识别，诊断和预测淋巴瘤存活的方法
公开(公告)号：US20050164231A1
公开(公告)日：2005-07-28
申请号：US10934930
申请日：2004-09-03
申请人： Louis Staudt , George Wright , Sandeep Dave , Bruce Tan
发明人： Louis Staudt , George Wright , Sandeep Dave , Bruce Tan
IPC分类号： C07H21/04 , C12Q20060101 , C12Q1/68 , G01N33/48 , G01N33/50 , G06F19/00
CPC分类号： G06F19/24 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G06F19/20 , Y02A90/26
摘要： Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.
摘要翻译：基因表达数据为更准确地鉴定和诊断淋巴组织增生性疾病提供了基础。此外，基因表达数据可用于开发更准确的生存预测因子。本发明公开了基于基因表达模式鉴定，诊断和预测淋巴瘤或淋巴组织增生性疾病存活的方法。本发明公开了一种用于从淋巴瘤样品获得基因表达数据的新型微阵列Lymph Dx微阵列。本发明还公开了多种利用淋巴瘤基因表达数据来确定特定淋巴瘤的身份并预测患有特定淋巴瘤的受试者的存活的方法。该信息将有助于开发与特定受试者一起使用的治疗方法。

5. 发明申请

US20070105136A1 Methods for identifying, diagnosing, and predicting survival of lymphomas 有权
标题翻译：识别，诊断和预测淋巴瘤存活的方法
公开(公告)号：US20070105136A1
公开(公告)日：2007-05-10
申请号：US11493387
申请日：2006-07-25
申请人： Louis Staudt , George Wright , Sandeep Dave , Bruce Tan , John Powell , Wyndham Wilson , Elaine Jaffe , Wing Chan , Timothy Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zettl , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaloy , Harald Holte , Jan Delabie , T. Andrew Lister
发明人： Louis Staudt , George Wright , Sandeep Dave , Bruce Tan , John Powell , Wyndham Wilson , Elaine Jaffe , Wing Chan , Timothy Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zettl , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaloy , Harald Holte , Jan Delabie , T. Andrew Lister
IPC分类号： C12Q1/68 , G06F19/00
CPC分类号： G01N33/6842 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G01N2333/51 , G06F19/20 , G06F19/24 , Y02A90/26
摘要： Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.
摘要翻译：基因表达数据为更准确地鉴定和诊断淋巴组织增生性疾病提供了基础。此外，基因表达数据可用于开发更准确的生存预测因子。本发明公开了基于基因表达模式鉴定，诊断和预测淋巴瘤或淋巴组织增生性疾病存活的方法。本发明公开了一种用于从淋巴瘤样品获得基因表达数据的新型微阵列Lymph Dx微阵列。本发明还公开了多种利用淋巴瘤基因表达数据来确定特定淋巴瘤的身份并预测患有特定淋巴瘤的受试者的存活的方法。该信息将有助于开发与特定受试者一起使用的治疗方法。

6. 发明申请

US20150132297A1 SURVIVAL PREDICTOR FOR DIFFUSE LARGE B CELL LYMPHOMA 审中-公开
标题翻译：用于DIFFUSE大型B细胞淋巴瘤的存活预防剂
公开(公告)号：US20150132297A1
公开(公告)日：2015-05-14
申请号：US14540302
申请日：2014-11-13
申请人： Lisa Rimsza , Andrew T. Lister , Wing C. Chan , Dennis Weisenburger , Jan Delabie , Erlend B. Smeland , Harald Holte , Stein Kvaloy , Rita M. Braziel , Richard I. Fisher , Pedro Jares , Armando Lopez-Guillermo , Elias Campo Guerri , Elaine S. Jaffe , Georg Lenz , Wyndham H. Wilson , George Wright , Sandeep S. Dave , Louis M. Staudt , Randy D. Gascoyne , Joseph M. Connors , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , German Ott
发明人： Lisa Rimsza , Andrew T. Lister , Wing C. Chan , Dennis Weisenburger , Jan Delabie , Erlend B. Smeland , Harald Holte , Stein Kvaloy , Rita M. Braziel , Richard I. Fisher , Pedro Jares , Armando Lopez-Guillermo , Elias Campo Guerri , Elaine S. Jaffe , Georg Lenz , Wyndham H. Wilson , George Wright , Sandeep S. Dave , Louis M. Staudt , Randy D. Gascoyne , Joseph M. Connors , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , German Ott
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/57407 , G01N2800/52 , G01N2800/56
摘要： The invention provides methods and materials related to a gene expression-based survival predictor for DLBCL patients.
摘要翻译：本发明提供了与DLBCL患者的基于表达的生存预测因子相关的方法和材料。

7. 发明申请

US20110195064A1 SURVIVAL PREDICTOR FOR DIFFUSE LARGE B CELL LYMPHOMA 审中-公开
标题翻译：用于DIFFUSE大型B细胞淋巴瘤的生存预后
公开(公告)号：US20110195064A1
公开(公告)日：2011-08-11
申请号：US12996489
申请日：2009-06-05
申请人： Lisa Rimsza , Andrew T. Lister , Dennis Weisenburger , Jan Delabie , Erlend B. Smeland , Harald Holte , Stein Kvaloy , Rita M. Braziel , Richard I. Fisher , Pedro Jares , Armando Lopez-Guillermo , Elias Campo Guerri , Elaine S. Jaffe , Georg Lenz , Wyndham H. Wilson , George Wright , Sandeep S. Dave , Louis M. Staudt , Randy D. Gascoyne , Joseph M. Connors , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , German Ott
发明人： Lisa Rimsza , Andrew T. Lister , Dennis Weisenburger , Jan Delabie , Erlend B. Smeland , Harald Holte , Stein Kvaloy , Rita M. Braziel , Richard I. Fisher , Pedro Jares , Armando Lopez-Guillermo , Elias Campo Guerri , Elaine S. Jaffe , Georg Lenz , Wyndham H. Wilson , George Wright , Sandeep S. Dave , Louis M. Staudt , Randy D. Gascoyne , Joseph M. Connors , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , German Ott
IPC分类号： A61K39/395 , C40B30/00 , A61P35/00 , G06F19/00
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/57407 , G01N2800/52 , G01N2800/56
摘要： The invention provides methods and materials related to a gene expression-based survival predictor for diffuse large B cell lymphoma (DLBCL) patients.
摘要翻译：本发明提供了与弥漫性大B细胞淋巴瘤（DLBCL）患者的基于基因表达的存活预测因子相关的方法和材料。

8. 发明授权

US08636652B2 Endoscope designs and methods of manufacture 有权
标题翻译：内窥镜设计和制造方法
公开(公告)号：US08636652B2
公开(公告)日：2014-01-28
申请号：US13176681
申请日：2011-07-05
申请人： George Wright , Kais Almarzouk , Lonnie R. Hoyle
发明人： George Wright , Kais Almarzouk , Lonnie R. Hoyle
IPC分类号： A61B1/00 , G02B23/24
CPC分类号： A61B1/00096 , A61B1/00179 , A61B1/042 , A61B1/055 , A61B1/0676 , A61B1/0684 , A61B1/07 , A61B1/3137
摘要： Various embodiments of the present invention comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include at least one solid state emitter such as a light emitting diode (LED) that is inserted into the body cavity to provide illumination therein. Certain embodiments of the invention comprise disposable endoscopes that can be fabricated relatively inexpensively such that discarding these endoscopses after a single use is cost-effective. The endoscope may comprise a lens holder on a distal end of the endoscope for collection of light reflected from surfaces within the body in which the endoscope is inserted. This lens holder may have an inner cavity through which light passes along an optical path. Reflective surfaces on sidewalls of the inner cavity may direct light along this optical path. The endoscope may further comprise an elongated support structure for supporting a plurality of lenses disposed along the optical path. This optical path may lead to a detector onto which images are formed.
摘要翻译：本发明的各种实施例包括用于观察身体的空腔内的内窥镜，例如像静脉或动脉的血管。这些内窥镜可以包括至少一个固态发射器，例如插入到体腔中以在其中提供照明的发光二极管（LED）。本发明的某些实施例包括可相对廉价地制造的一次性内窥镜，使得在单次使用后丢弃这些内窥镜是成本有效的。内窥镜可以包括在内窥镜的远端上的透镜保持器，用于收集从插入内窥镜的主体内的表面反射的光。该透镜保持器可以具有内部空腔，光沿光路通过该内腔。内腔侧壁上的反射面可沿着该光路引导光。内窥镜还可以包括用于支撑沿着光路布置的多个透镜的细长支撑结构。该光路可能导致形成有图像的检测器。

9. 发明授权

US4526128A High-speed indexing feed screw conveyer 失效
标题翻译：高速分度进料螺旋输送机
公开(公告)号：US4526128A
公开(公告)日：1985-07-02
申请号：US579434
申请日：1984-02-13
申请人： Joseph Sorace , George Wright
发明人： Joseph Sorace , George Wright
IPC分类号： B05B13/02 , B65G33/06 , B05B7/06 , B05C5/00
CPC分类号： B05B13/0221 , B65G33/06 , Y10S118/03
摘要： A vertical-feed conveyor for cylindrical objects and the like utilized twin counter-rotating helical feed screws. The thread of the feed screws is shaped so as to create conveyance troughs which are closely dimensioned to the object to be moved. The variable pitch of the screws creates zones of acceleration, deceleration and dwell so that the objects may be sequentially delivered to predetermined indexing stations where various processes may be performed upon the objects such as; internal spray coating, capping, electronic non-destructive testing, etc. The points of dwell along the feed screws are achieved by the shape of the radial sidewalls of the feed screws which at those points extend part way around the screw in radial planes of the screw.
摘要翻译：用于圆柱形物体等的垂直进料输送机使用双反向旋转螺旋进给螺杆。进给螺杆的螺纹成形，以便形成与要移动的物体相近的尺寸的输送槽。螺钉的可变螺距产生加速度，减速度和停留的区域，使得物体可以顺序地传递到预定的分度工位，其中可以对诸如以下物体执行各种过程; 内部喷涂，封盖，电子非破坏性测试等。沿着进给螺钉的停留点是通过进给螺钉的径向侧壁的形状实现的，这些点在这些点的径向平面内围绕螺钉部分地延伸拧。

10. 发明申请

US20110184239A1 METHODS AND SYSTEMS FOR DISABLING AN ENDOSCOPE AFTER USE 审中-公开
标题翻译：使用后消除内镜的方法和系统
公开(公告)号：US20110184239A1
公开(公告)日：2011-07-28
申请号：US12974452
申请日：2010-12-21
申请人： George Wright , Lonnie Hoyle , Kais Almarzouk
发明人： George Wright , Lonnie Hoyle , Kais Almarzouk
IPC分类号： A61B1/00
CPC分类号： A61B1/00016 , A61B1/00029 , A61B1/00032 , A61B1/00062 , A61B1/0676 , A61B1/0684 , A61B2560/0276
摘要： Various embodiments comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include a usage detector and a disabling device coupled to the usage detector, wherein the disabling device is configured to disable the endoscope at least partly in response to an electrical, optical, and/or mechanical output from the usage detector.
摘要翻译：各种实施例包括用于在诸如静脉或动脉的血管的身体的空腔内观察的内窥镜。这些内窥镜可以包括使用检测器和耦合到使用检测器的禁用装置，其中禁用装置被配置为至少部分地响应于来自使用检测器的电，光学和/或机械输出来禁用内窥镜。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式