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1. 发明授权

US08317772B2 Catheter with composite stiffener 有权
标题翻译：导管与复合加强筋
公开(公告)号：US08317772B2
公开(公告)日：2012-11-27
申请号：US13045102
申请日：2011-03-10
申请人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
发明人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M25/005 , A61M25/0054
摘要： A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.
摘要翻译：导管，其包括具有近端，远端和限定在所述近端和远端之间延伸的内腔的通道的细长管状构件。细长管状构件包括相对刚性的近端部分和相对柔性的远端部分。近端部分包括内部管状衬垫，包括金属合金的第一加强件和包括非金属合金的第二加强件。第一和第二加强件同轴地缠绕在近端内衬的外部。远侧部分包括远侧内部管状衬垫，并且第二加强件同轴地缠绕在远端内衬套的外部。第一加强件在到达远端部分之前终止。

2. 发明授权

US07909812B2 Catheter with composite stiffener 有权
标题翻译：导管与复合加强筋
公开(公告)号：US07909812B2
公开(公告)日：2011-03-22
申请号：US11516061
申请日：2006-09-06
申请人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
发明人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M25/005 , A61M25/0054
摘要： A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.
摘要翻译：导管，其包括具有近端，远端和限定在所述近端和远端之间延伸的内腔的通道的细长管状构件。细长管状构件包括相对刚性的近端部分和相对柔性的远端部分。近端部分包括内部管状衬垫，包括金属合金的第一加强件和包括非金属合金的第二加强件。第一和第二加强件同轴地缠绕在近端内衬的外部。远侧部分包括远侧内部管状衬垫，并且第二加强件同轴地缠绕在远端内衬套的外部。第一加强件在到达远端部分之前终止。

3. 发明申请

US20110172643A1 Catheter with Composite Stiffener 有权
标题翻译：导管与复合加强筋
公开(公告)号：US20110172643A1
公开(公告)日：2011-07-14
申请号：US13045102
申请日：2011-03-10
申请人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
发明人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M25/005 , A61M25/0054
摘要： A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.
摘要翻译：导管，其包括具有近端，远端和限定在所述近端和远端之间延伸的内腔的通道的细长管状构件。细长管状构件包括相对刚性的近端部分和相对柔性的远端部分。近端部分包括内部管状衬垫，包括金属合金的第一加强件和包括非金属合金的第二加强件。第一和第二加强件同轴地缠绕在近端内衬的外部。远侧部分包括远侧内部管状衬垫，并且第二加强件同轴地缠绕在远端内衬套的外部。第一加强件在到达远端部分之前终止。

4. 发明授权

US07104979B2 Catheter with composite stiffener 有权
公开(公告)号：US07104979B2
公开(公告)日：2006-09-12
申请号：US10079103
申请日：2002-02-19
申请人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
发明人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M25/005 , A61M25/0054
摘要： A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.

5. 发明授权

US06368316B1 Catheter with composite stiffener 失效
公开(公告)号：US06368316B1
公开(公告)日：2002-04-09
申请号：US09096267
申请日：1998-06-11
申请人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
发明人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
IPC分类号： A61M2500
CPC分类号： A61M25/0053 , A61M25/005 , A61M25/0054
摘要： A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.

6. 发明授权

US06165163A Soft-tip performance braided catheter 有权
标题翻译：软尖性能编织导管
公开(公告)号：US06165163A
公开(公告)日：2000-12-26
申请号：US277010
申请日：1999-03-26
申请人： Thomas Yung-Hui Chien , Lex P. Jansen , Henry Nita , Jeffrey A. Sarge
发明人： Thomas Yung-Hui Chien , Lex P. Jansen , Henry Nita , Jeffrey A. Sarge
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M25/0054 , A61M2025/0081
摘要： This is a catheter assembly which may be used in accessing a tissue target within the body, typically a target which is accessible through the vascular system. Central to the invention is the use of a braided metallic reinforcing member, typically of a stainless steel or super-elastic alloy ribbon, situated within the catheter body in such a way to create a catheter section having a thin wall, controlled stiffness, and high resistance to kinking. The distal-most section of the catheter is much more flexible than are other braided catheters of the genre due to choice of braid construction features of that distal-most section. The distal-most braid, and optionally, intermediate braid components are constructed to be more flexible than the more proximal sections due to deletion of ribbons from the braid structure, change of ribbon material, and change of pitch. The various sections include braids which may have a consistent pitch or may vary in pitch along the axis of the catheter or catheter section. The braided ribbon reinforcing member typically is placed between a flexible outer tubing member and an inner tubing member to produce a catheter section which is very flexible but highly kink resistant. The more proximal sections of the catheter assembly are often substantially stiffer than the more distal sections also due to the presence of stiff polymeric tubing or composited materials in the stiffer section.
摘要翻译：这是一种导管组件，其可以用于进入身体内的组织靶，通常是可通过血管系统接近的靶。本发明的中心是使用通常为不锈钢或超弹性合金带的编织金属加强件，其位于导管主体内，以便产生具有薄壁，受控刚度和高度的导管部分耐扭结。由于选择最远部分的编织结构特征，导管的最远端部分比其他类型的编织导管更加灵活。最远的编织物和任选的中间编织部件被构造成比近侧部分更柔软，这是由于从编织结构中删除丝带，带状材料的变化和间距的变化。各个部分包括可以具有一致间距的编织物或者可以沿着导管或导管部分的轴线的间距变化。编织带加强构件通常放置在柔性外管构件和内管构件之间以产生非常柔性但高度扭结的导管部分。导管组件的近端部分通常比较远的部分基本上更硬，这也是由于在刚性部分中存在刚性聚合物管或复合材料。

7. 发明授权

US5891114A Soft-tip high performance braided catheter 失效
标题翻译：软尖高性能编织导管
公开(公告)号：US5891114A
公开(公告)日：1999-04-06
申请号：US941511
申请日：1997-09-30
申请人： Thomas Yung-Hui Chien , Lex P. Jansen , Henry Nita , Jeffrey A. Sarge
发明人： Thomas Yung-Hui Chien , Lex P. Jansen , Henry Nita , Jeffrey A. Sarge
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M2025/0081 , A61M25/0054
摘要： This is a catheter assembly which may be used in accessing a tissue target within the body, typically a target which is accessible through the vascular system. Central to the invention is the use of a braided metallic reinforcing member, typically of a stainless steel or super-elastic alloy ribbon, situated within the catheter body in such a way to create a catheter section having a thin wall, controlled stiffness, and high resistance to kinking. The distal-most section of the catheter is much more flexible than are other braided catheters of the genre due to choice of braid construction features of that distal-most section. The distal-most braid, and optionally, intermediate braid components are constructed to be more flexible than the more proximal sections due to deletion of ribbons from the braid structure, change of ribbon material, and change of pitch. The various sections include braids which may have a consistent pitch or may vary in pitch along the axis of the catheter or catheter section. The braided ribbon reinforcing member typically is placed between a flexible outer tubing member and an inner tubing member to produce a catheter section which is very flexible but highly kink resistant. The more proximal sections of the catheter assembly are often substantially stiffer than the more distal sections also due to the presence of stiff polymeric tubing or composited materials in the stiffer section.
摘要翻译：这是一种导管组件，其可以用于进入身体内的组织靶，通常是可通过血管系统接近的靶。本发明的中心是使用通常为不锈钢或超弹性合金带的编织金属加强件，其位于导管主体内，以便产生具有薄壁，受控刚度和高度的导管部分耐扭结。由于选择最远部分的编织结构特征，导管的最远端部分比其他类型的编织导管更加灵活。最远的编织物和任选的中间编织部件被构造成比近侧部分更柔软，这是由于从编织结构中删除丝带，带状材料的变化和间距的变化。各个部分包括可以具有一致间距的编织物或者可以沿着导管或导管部分的轴线的间距变化。编织带加强构件通常放置在柔性外管构件和内管构件之间以产生非常柔性但高度扭结的导管部分。导管组件的近端部分通常比较远的部分基本上更硬，这也是由于在刚性部分中存在刚性聚合物管或复合材料。

8. 发明授权

US07338511B2 Solid embolic material with variable expansion 失效
标题翻译：固体栓塞材料，膨胀可变
公开(公告)号：US07338511B2
公开(公告)日：2008-03-04
申请号：US10155563
申请日：2002-05-24
申请人： Gregory E. Mirigian , Huey Quoc Chan , Thomas Yung-Hui Chien , Stephen C. Porter , Robert P. Eury
发明人： Gregory E. Mirigian , Huey Quoc Chan , Thomas Yung-Hui Chien , Stephen C. Porter , Robert P. Eury
IPC分类号： A61M29/00
CPC分类号： A61B17/12195 , A61B17/12022 , A61B17/12113 , A61B17/12136 , A61B17/12186 , A61B2017/1205 , A61B2017/12063
摘要： A solid embolic material that is capable of filling irregularly shaped and asymmetrical vascular defects in a controlled and predictable manner, without the difficulties associated with delivery of the embolic material through a microcatheter and containment of the embolic material in a defect. A detachable embolic balloon with optional check valve for maintaining liquid in the balloon prior to curing and optional multi-leaflet covering to prevent the balloon from expanding into the native vascular lumen.
摘要翻译：一种固体栓塞材料，其能够以受控和可预测的方式填充不规则形状和不对称的血管缺陷，而不需要通过微导管输送栓塞材料并将栓塞材料容纳在缺陷中。一种可拆卸的栓塞气囊，其具有可选的止回阀，用于在固化之前保持气囊中的液体，并且可选的多叶片覆盖物以防止气囊扩张到天然血管腔中。

9. 发明授权

US06527790B2 Intravascular balloon catheter for embolic coil delivery 有权
公开(公告)号：US06527790B2
公开(公告)日：2003-03-04
申请号：US09732476
申请日：2000-12-07
申请人： Thomas Yung-Hui Chien , Greg P. Welsh , Huey Quoc Chan
发明人： Thomas Yung-Hui Chien , Greg P. Welsh , Huey Quoc Chan
IPC分类号： A61M2902
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12136 , A61B17/12145 , A61B90/39 , A61B2017/00557 , A61B2017/1205 , A61B2017/22052 , A61B2017/22068 , A61B2017/22069
摘要： Improved intravascular balloon catheters for the delivery of embolic agents and devices such as coils to wide-neck aneurysms. In one embodiment, the present invention provides a balloon catheter having a combined guide wire/delivery lumen and a lateral delivery hole. The balloon may comprise a multi-lobed design with the delivery hole disposed between adjacent balloon lobes. The balloon catheter preferably includes a diversion member disposed in the combined lumen to cause the embolic device to divert from the combined lumen, through the delivery hole, and into the wide-neck aneurysm. In another embodiment, the present invention provides a balloon catheter having a shaft including a shaft tube and a co-extending embolic delivery tube. The delivery tube terminates proximal of the distal end of the shaft tube for added flexibility, and the balloon may inflate eccentrically to push the distal opening of the delivery lumen adjacent the opening of the wide-neck aneurysm.

10. 发明授权

US06547804B2 Selectively permeable highly distensible occlusion balloon 有权
标题翻译：选择性高透气性高密度闭塞气囊
公开(公告)号：US06547804B2
公开(公告)日：2003-04-15
申请号：US09748972
申请日：2000-12-27
申请人： Stephen Christopher Porter , Thomas Yung-Hui Chien , Huey Quoc Chan
发明人： Stephen Christopher Porter , Thomas Yung-Hui Chien , Huey Quoc Chan
IPC分类号： A61M2902
CPC分类号： A61B17/12186 , A61B17/12022 , A61B17/12113 , A61B17/12136 , A61B17/1219 , A61M2025/1054
摘要： A process and apparatus for occluding a vascular site. A catheter having a highly distensible occlusion balloon detachably mounted at a distal end thereof is provided to the vascular site and at least partially filled with an aqueous balloon inflation fluid which allows the balloon placement to be imaged. The balloon is porous to the aqueous inflation fluid and the inflation fluid is gradually displaced through the balloon pores by a liquid filling composition which is solidifiable on contact with the aqueous inflation fluid to produce a mass to which the balloon is nonporous. The filing composition is injected to bring the balloon wall into contact with the vessel wall at the vascular site. The balloon is detached from the catheter after the filling composition has at least substantially solidified and the catheter removed from the body.
摘要翻译：用于闭塞血管部位的方法和装置。具有可分离地安装在其远端处的高度可扩张的闭塞球囊的导管被提供到血管部位，并且至少部分地填充有允许气囊放置成像的水性球囊充气流体。气囊对水性充气流体是多孔的，并且膨胀流体通过液体填充组合物逐渐移位通过球囊孔隙，该液体填充组合物在与水性膨胀流体接触时可固化，以产生气球无孔的质量。注射该组合物以使球囊壁与血管部位处的血管壁接触。在填充组合物至少基本上固化并且导管从身体移除之后，气囊与导管分离。

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