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1. 发明申请

US20050171163A1 MCP-1 receptor antagonists and methods of use thereof 失效
标题翻译： MCP-1受体拮抗剂及其使用方法
公开(公告)号：US20050171163A1
公开(公告)日：2005-08-04
申请号：US10442917
申请日：2003-05-21
申请人： Larry Bratton , Alexander Bridges , David Connor , Steven Miller , Yuntao Song , Kuai-Lin Sun , Bharat Trivedi , Paul Unangst
发明人： Larry Bratton , Alexander Bridges , David Connor , Steven Miller , Yuntao Song , Kuai-Lin Sun , Bharat Trivedi , Paul Unangst
IPC分类号： C07D233/64 , A61K31/10 , A61K31/121 , A61K31/167 , A61K31/22 , A61K31/341 , A61K31/381 , A61K31/4164 , A61K31/42 , A61K31/421 , A61K31/426 , A61K31/4402 , A61K31/4439 , A61P9/10 , A61P19/02 , A61P29/00 , A61P37/06 , A61P43/00 , C07C311/03 , C07C311/27 , C07C317/18 , C07C317/24 , C07C317/28 , C07C317/44 , C07C323/22 , C07D213/44 , C07D213/50 , C07D233/54 , C07D239/26 , C07D261/08 , C07D263/32 , C07D277/10 , C07D277/26 , C07D307/40 , C07D307/46 , C07D307/71 , C07D307/80 , C07D333/18 , C07D333/22 , C07D333/38 , C07D333/44 , C07D413/02 , C07D413/04
CPC分类号： C07C311/03 , C07C311/27 , C07C317/18 , C07C317/24 , C07C317/28 , C07C317/44 , C07D213/50 , C07D233/64 , C07D239/26 , C07D261/08 , C07D263/32 , C07D277/10 , C07D277/26 , C07D307/46 , C07D307/71 , C07D307/80 , C07D333/22 , C07D333/38 , C07D333/44 , C07D413/04
摘要： The present invention relates to sulfones that are useful in the treatment of chemokine-mediated disorders. In certain embodiments, the present invention concerns the compounds that are MCP-1 receptor antagonists.
摘要翻译：本发明涉及可用于治疗趋化因子介导的病症的砜。在某些实施方案中，本发明涉及作为MCP-1受体拮抗剂的化合物。

2. 发明授权

US4014806A Novel organopolyphosphates in aqueous cleaning compositions 失效
标题翻译：水性清洁组合物中的新型有机多磷酸盐
公开(公告)号：US4014806A
公开(公告)日：1977-03-29
申请号：US420579
申请日：1973-12-07
申请人： David Connor , Francesco Cuciti , Edward James Lowe
发明人： David Connor , Francesco Cuciti , Edward James Lowe
IPC分类号： C11D1/04 , C11D1/22 , C11D1/29 , C11D1/37 , C11D3/06 , C11D3/30 , C11D17/00 , C11D3/065 , C11D3/36 , C11D17/08
CPC分类号： C11D3/06 , C11D10/042 , C11D3/30 , C11D1/22 , C11D1/29
摘要： Novel organic polyphosphate mixtures are made by a process comprising a mixture of a plurality of polyphosphate salts of one or more primary, secondary or tertiary amines; which mixture has been obtained by a process comprising (1) forming an aqueous polyphosphoric acid solution comprising from 80 to 88% by weight of phosphorus penitoxide; (2) reacting said polyphosphoric acid solution with a primary, secondary or tertiary amine at a pH of from 4 to 12 and at a temperature of from 15 to 70.degree. C.Such mixtures are useful as builders in liquid cleaning compositions comprising surface active agents or alkali metal hydroxides or silicates with which they are more compatible in aqueous solution then are previously used polyphosphate builder materials.
摘要翻译：新的有机多磷酸盐混合物通过包括多种一种或多种伯，仲或叔胺的多磷酸盐的混合物的方法制备; 该混合物是通过以下方法获得的：（1）形成含有80-88％（重量）的氧化磷的多磷酸水溶液; （2）使所述多磷酸溶液与pH为4至12，温度为15至70℃的伯胺，仲胺或叔胺反应。

3. 发明授权

US5544737A Conveyor devices 失效
标题翻译：输送装置
公开(公告)号：US5544737A
公开(公告)日：1996-08-13
申请号：US389508
申请日：1995-02-16
申请人： David Connor
发明人： David Connor
IPC分类号： B65G21/04 , B65G35/00
CPC分类号： B65G17/20 , B65G21/04
摘要： An easily transportable self-powered conveyor device, for use e.g. in transporting pieces of wood over rough terrain, has a drive chain and driven disc installed on a chainsaw in place of a saw chain and bar, the drive chain being in driving engagement with the driven disc. A sheave is connected to an output of a reduction gearing for rotation thereby and a rope extends around the sheave, with securing devices attached to the rope and spaced apart along the rope for temporarily securing objects to the rope for conveyance thereby as the rope is pulled by the sheave. A retaining device anchors the sheave to any suitable support, e.g. a tree.
摘要翻译：一种易于运输的自供电输送装置，在崎岖的地形上运输木材，具有安装在电锯上的驱动链和驱动盘代替锯链和杆，驱动链与从动盘驱动接合。绳轮连接到减速齿轮的输出端，用于旋转，绳索围绕绳轮延伸，固定装置连接到绳索上并沿着绳索间隔开，用于将物体临时固定到绳索以便随着绳索被拉动而传送由滑轮保持装置将滑轮锚固到任何合适的支撑件，例如一颗树。

4. 发明申请

US20060232661A1 System and method for correcting scan position errors in an imaging system 失效
标题翻译：用于校正成像系统中扫描位置误差的系统和方法
公开(公告)号：US20060232661A1
公开(公告)日：2006-10-19
申请号：US11087714
申请日：2005-03-24
申请人： M. Niland , David Connor , Donald Troxel , John Connolly
发明人： M. Niland , David Connor , Donald Troxel , John Connolly
IPC分类号： B41J2/435
CPC分类号： B41J2/471
摘要： Embodiments of the invention provide systems and methods for correcting scan position errors in an imaging system. In one embodiment of the present invention, the method includes determining an image beam velocity error as a function of a position within a scan line of an image, and using the image beam velocity error to determine a plurality of pixel clock frequencies to be respectively applied to a plurality of positions within the scan line.
摘要翻译：本发明的实施例提供了用于校正成像系统中的扫描位置误差的系统和方法。在本发明的一个实施例中，该方法包括根据图像的扫描线内的位置确定图像束速度误差，并且使用图像束速度误差来确定要分别应用的多个像素时钟频率到扫描线内的多个位置。

5. 发明申请

US20060025396A1 Isophthalic acid derivatives as matrix metalloproteinase inhibitors 失效
标题翻译：间苯二甲酸衍生物作为基质金属蛋白酶抑制剂
公开(公告)号：US20060025396A1
公开(公告)日：2006-02-02
申请号：US11238502
申请日：2005-09-29
申请人： Nicole Barvian , David Connor , Richard Dyer , Adam Johnson , William Patt
发明人： Nicole Barvian , David Connor , Richard Dyer , Adam Johnson , William Patt
IPC分类号： A61K31/455 , A61K31/195 , A61K31/192 , C07C235/78
CPC分类号： C07D213/30 , C07C69/80 , C07C69/90 , C07C69/92 , C07C229/60 , C07C233/66 , C07C233/69 , C07C233/73 , C07C233/75 , C07C233/78 , C07C235/60 , C07D285/14 , C07D317/54 , C40B50/14
摘要： Selective MMP-13 inhibitors are isophthalic acid derivatives of the formula wherein: R1, R2, and R3 independently are hydrogen, halo, hydroxy, C1-C6 alkyl, C1-C6 alkoxy, C2-C6 alkenyl, C2-C6 alkynyl, NO2, NR4R5, CN, or CF3; E is independently O or S; A and B independently are OR4 or NR4R5; each R4 and R5 independently are H, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, (CH2)n aryl, (CH2)n cycloalkyl, (CH2)n heteroaryl, or R4 and R5 when taken together with the nitrogen to which they are attached complete a 3- to 8-membered ring, optionally containing a heteroatom selected from O, S, or NH, and optionally substituted or unsubstituted; n is 0 to 6; or a pharmaceutically acceptable salt thereof. The compounds are useful for treating diseases in a mammal that are mediated by MMP enzymes.
摘要翻译：选择性MMP-13抑制剂是下式的间苯二甲酸衍生物，其中：R 1，R 2和R 3独立地是氢，卤素，羟基，C 1 -C 6烷基，C 1 -C 6烷氧基，C 2 -C 6烷基，C 1 -C 6烷基，C 1 -C 6烷基， C 1 -C 6亚烷基，C 2 -C 6炔基，NO 2，NR 2， 4，R 5，CN或CF 3; E独立地为O或S; A和B独立地为OR 4或NR 4 R 5; 每个R 4和R 5独立地是H，C 1 -C 6烷基，C 2 C 1 -C 6亚烷基，C 2 -C 6炔基，（CH 2 2）（CH 2）2芳基，（CH 2）2芳基，（CH 2 CH 2）n个杂芳基，或R 4和R 5与它们所连接的氮原子一起形成3至8元环，任选含有选自O，S的杂原子，或NH，并且任选取代或未取代; n为0〜6; 或其药学上可接受的盐。该化合物可用于治疗由MMP酶介导的哺乳动物中的疾病。

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