专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2007114916A3 ARYLBENZYLPIPERIDINE COMPOUNDS 审中-公开
标题翻译：亚苄基哌啶化合物
公开(公告)号：WO2007114916A3
公开(公告)日：2008-07-31
申请号：PCT/US2007008291
申请日：2007-04-02
申请人： LUNDBECK & CO AS H , MARZABADI MOHAMMAD , CHEN CHIEN-AN , YU JIANG , REITMAN MICHAEL , KIM ANDERSEN
发明人： MARZABADI MOHAMMAD , CHEN CHIEN-AN , YU JIANG , REITMAN MICHAEL , KIM ANDERSEN
IPC分类号： G09B3/00
CPC分类号： A61K31/00
摘要： This invention is directed to arylbenzylpiperidine compounds which are ligands at the MCHl receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression comprising administering to the subject a therapeutically effective amount of a compound of the subject invention. This invention further provides a method of treating a subject suffering from anxiety comprising administering to the subject a therapeutically effective amount of a compound of the subject invention. This invention also provides a method of treating a subject suffering from obesity comprising administering to the subject a therapeutically effective amount of a compound of the subject invention. Furthermore, the present invention is directed to the use of a compound of the subject invention for the manufacture of a medicament for treating a subject suffering from depression, anxiety or obesity.
摘要翻译：本发明涉及作为MCH1受体的配体的芳基苄基哌啶化合物。本发明提供了包含治疗有效量的本发明化合物和药学上可接受的载体的药物组合物。本发明还提供了治疗患有抑郁症的受试者的方法，其包括向受试者施用治疗有效量的本发明化合物。本发明还提供了治疗患有焦虑症的受试者的方法，其包括向受试者施用治疗有效量的本发明化合物。本发明还提供了治疗患有肥胖症的受试者的方法，包括向受试者施用治疗有效量的本发明化合物。此外，本发明涉及本发明化合物在制备用于治疗患有抑郁症，焦虑症或肥胖症的受试者的药物中的用途。

2. 发明申请

WO2007114902A2 ALKYLTHIOBENZYLPIPERIDINE COMPOUNDS 审中-公开
标题翻译：烷基二苯基哌啶化合物
公开(公告)号：WO2007114902A2
公开(公告)日：2007-10-11
申请号：PCT/US2007008142
申请日：2007-04-02
申请人： LUNDBECK & CO AS H , MARZABADI MOHAMMAD , ANDERSEN KIM , CHEN BIN , REITMAN MICHAEL , JIANG YU , ELDEMENKY EMAN
发明人： MARZABADI MOHAMMAD , ANDERSEN KIM , CHEN BIN , REITMAN MICHAEL , JIANG YU , ELDEMENKY EMAN
IPC分类号： C02F1/00
CPC分类号： C07D211/26 , C07D405/12
摘要： This invention is directed to alkylthiobenzylpiperidine compounds which are ligands at the MCHl receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression comprising administering to the subject a therapeutically effective amount of a compound of the subject invention. This invention further provides a method of treating a subject suffering from anxiety comprising administering to the subject a therapeutically effective amount of a compound of the subject invention. This invention also provides a method of treating a subject suffering from obesity comprising administering to the subject a therapeutically effective amount of a compound of the subject invention. Furthermore, the present invention is directed to the use of a compound of the subject invention for the manufacture of a medicament for treating a subject suffering from depression, anxiety or obesity.
摘要翻译：本发明涉及作为MCH1受体的配体的烷硫基苄基哌啶化合物。本发明提供了包含治疗有效量的本发明化合物和药学上可接受的载体的药物组合物。本发明还提供了治疗患有抑郁症的受试者的方法，包括向受试者施用治疗有效量的本发明化合物。本发明还提供了治疗患有焦虑症的受试者的方法，其包括向受试者施用治疗有效量的本发明化合物。本发明还提供了治疗患有肥胖症的受试者的方法，包括向受试者施用治疗有效量的本发明化合物。此外，本发明涉及本发明化合物在制备用于治疗患有抑郁，焦虑或肥胖的受试者的药物中的用途。

3. 发明公开

EP1556351A4 SECONDARY AMINO ANILINIC PIPERIDINES AS MCH1 ANTAGONISTS AND USES THEREOF 审中-公开
标题翻译：二级AMINOANILINPIPERIDINE AS MCH1拮抗剂及其用途
公开(公告)号：EP1556351A4
公开(公告)日：2007-07-25
申请号：EP03763374
申请日：2003-07-03
申请人： LUNDBECK & CO AS H
发明人： MARZABADI MOHAMMAD , JIANG ALLEN , LU KAI , CHEN CHIEN-AN , DELEON JOHN , WETZEL JOHN
IPC分类号： C07D211/70 , A61K31/44 , A61K31/451 , A61K31/4545 , A61K31/506 , A61P3/04 , A61P13/02 , A61P25/00 , A61P25/22 , A61P25/24 , A61P43/00 , C07D211/26 , C07D401/12
CPC分类号： C07D211/26 , C07D401/12

4. 发明公开

EP1531816A4 SPIROCYCLIC PIPERIDINES AS MCH1 ANTAGONISTS AND USES THEREOF 有权
标题翻译：作为MCH1拮抗剂的SPIROCYCLIC哌啶及其用途
公开(公告)号：EP1531816A4
公开(公告)日：2005-12-28
申请号：EP03763351
申请日：2003-07-03
申请人： LUNDBECK & CO AS H
发明人： MARZABADI MOHAMMAD , JIANG ALLEN , LU KAI , CHEN CHIEN-AN , DELEON JOHN , WETZEL JOHN , ANDERSEN KIM
IPC分类号： A61K31/438 , C07D221/20 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D491/10 , A61P3/04 , A61P25/00 , A61P25/24
CPC分类号： C07D221/20 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D491/10

5. 发明专利

EA008826B1 ВТОРИЧНЫЕ АМИНОАНИЛИНОВЫЕ ПИПЕРИДИНЫ В КАЧЕСТВЕ АНТАГОНИСТОВ МКГ1 И ИХ ПРИМЕНЕНИЕ 未知
公开(公告)号：EA008826B1
公开(公告)日：2007-08-31
申请号：EA200500152
申请日：2003-07-03
申请人： LUNDBECK & CO AS H
发明人： MARZABADI MOHAMMAD , JIANG YU , LU KAI , CHEN CHIEN-AN , DELEON JOHN , WETZEL JOHN
IPC分类号： C07D211/70 , A61K31/44 , A61K31/451 , A61K31/4545 , A61K31/506 , A61P3/04 , A61P13/02 , A61P25/22 , A61P25/24 , A61P43/00 , C07D211/26 , C07D401/12
摘要： Данноеизобретениенаправленонасоединения, которыеявляютсяселективнымиантагонистамирецепторов-1 меланинконцентрирующегогормона (МКГ-1). Визобретениипредлагаетсяфармацевтическаякомпозиция, включающаятерапевтическиэффективноеколичествосоединенияизобретенияи фармацевтическиприемлемыйноситель. Вданномизобретениипредлагаетсяфармацевтическаякомпозиция, полученнаяобъединениемтерапевтическиэффективногоколичествасоединенияданногоизобретенияи фармацевтическиприемлемогоносителя. Вданномизобретениидополнительнопредлагаетсяспособполученияфармацевтическойкомпозиции, включающийобъединениетерапевтическиэффективногоколичествасоединенийизобретенияи фармацевтическиприемлемогоносителя. Вданномизобретениитакжепредлагаетсяспособснижениямассытелау субъекта, которыйвключаетвведениесубъектуколичествасоединенияизобретения, эффективногодляснижениямассытелау субъекта. Вданномизобретениидополнительнопредлагаетсяспособлечениясубъекта, страдающегодепрессиейи/илитревожностью, которыйвключаетвведениесубъектуколичествасоединенияизобретения, эффективногодлялеченияу субъектадепрессиии/илитревожности. Вданномизобретениидополнительнопредлагаетсяспособлечениясубъекта, страдающегонарушениеммочеиспускания.

6. 发明专利

NO20050145L 未知
公开(公告)号：NO20050145L
公开(公告)日：2005-01-11
申请号：NO20050145
申请日：2005-01-11
申请人： LUNDBECK & CO AS H
发明人： WETZEL JOHN M , ANDERSEN KIM , DELEON JOHN E , JIANG YU , CHEN CHIEN-AN , LU KAI , MARZABADI MOHAMMAD
IPC分类号： A61K31/438 , C07D221/20 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D491/10
摘要： This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the body mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject=s depression and/or anxiety. This invention further provides a method of treating a subject suffering from a urinary disorder.

7. 发明专利

CA2485379A1 SECONDARY AMINO ANILINIC PIPERIDINES AS MCH1 ANTAGONISTS ANDUSES THEREOF 未知
公开(公告)号：CA2485379A1
公开(公告)日：2004-01-15
申请号：CA2485379
申请日：2003-07-03
申请人： LUNDBECK & CO AS H
发明人： JIANG YU , WETZEL JOHN , LU KAI , MARZABADI MOHAMMAD , DELEON JOHN , CHEN CHIEN-AN
IPC分类号： A61K31/44 , A61K31/451 , A61K31/4545 , A61K31/506 , A61P3/04 , A61P13/02 , A61P25/22 , A61P25/24 , A61P43/00 , C07D211/26 , C07D211/70 , C07D401/12
摘要： This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. Thi s invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a proce ss for making a pharmaceutical composition comprising combining a therapeutical ly effective amount of the compounds of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the bo dy mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering fro m depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject=s depression and/or anxiety. This invention further provides a method of treating a subject suffering from a urinary disorder.

8. 发明专利

AT421504T 未知
公开(公告)号：AT421504T
公开(公告)日：2009-02-15
申请号：AT03763351
申请日：2003-07-03
申请人： LUNDBECK & CO AS H
发明人： MARZABADI MOHAMMAD , JIANG ALLEN , LU KAI , CHEN CHIEN-AN , DELEON JOHN , WETZEL JOHN , ANDERSEN KIM
IPC分类号： C07D221/20 , A61K31/438 , A61P25/24 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D491/10
摘要： This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the body mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject=s depression and/or anxiety. This invention further provides a method of treating a subject suffering from a urinary disorder.

9. 发明专利

BRPI0406725A 未知
公开(公告)号：BRPI0406725A
公开(公告)日：2005-12-20
申请号：BRPI0406725
申请日：2004-01-06
申请人： LUNDBECK & CO AS H
发明人： MARZABADI MOHAMMAD , WETZEL JOHN , CHEN CHIEN-AN , JIANG YU , LU KAI
IPC分类号： A61K31/44 , A61K31/445 , A61K31/451 , A61K31/4523 , A61K31/4525 , A61K31/453 , A61K31/4535 , A61K31/454 , A61K31/4545 , A61K31/4709 , A61K31/497 , A61K31/506 , A61K31/53 , A61K31/5377 , A61P3/04 , A61P7/12 , A61P25/22 , A61P25/24 , A61P43/00 , C07D211/06 , C07D211/26 , C07D211/28 , C07D211/30 , C07D211/90 , C07D211/94 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/10 , C07D409/12 , C07D409/14 , C07D413/06 , C07D413/12 , C07D417/06 , C07D417/10 , C07D471/04 , C07D495/04 , C07D521/00
摘要： This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the body mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.

10. 发明专利

BR0312257A 未知
公开(公告)号：BR0312257A
公开(公告)日：2005-04-12
申请号：BR0312257
申请日：2003-07-03
申请人： LUNDBECK & CO AS H
发明人： MARZABADI MOHAMMAD , JIANG YU , LU KAI , CHEN CHIEN-AN , DELEON JOHN , WETZEL JOHN
IPC分类号： A61K31/44 , A61K31/451 , A61K31/4545 , A61K31/506 , A61P3/04 , A61P13/02 , A61P25/22 , A61P25/24 , A61P43/00 , C07D211/26 , C07D211/70 , C07D401/12
摘要： This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compounds of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the body mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject=s depression and/or anxiety. This invention further provides a method of treating a subject suffering from a urinary disorder.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式