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1. 发明申请

WO2013190073A1 ANALYTICAL TEST STRIP WITH CAPILLARY SAMPLE-RECEIVING CHAMBERS SEPARATED BY STOP JUNCTIONS 审中-公开
标题翻译：带停止接头分开的毛细管样品接收器的分析测试条
公开(公告)号：WO2013190073A1
公开(公告)日：2013-12-27
申请号：PCT/EP2013/062952
申请日：2013-06-20
申请人： LIFESCAN SCOTLAND LIMITED
发明人： WHITEHEAD, Neil , SLOSS, Scott , SMITH, Antony , WHYTE, Lynsey , MCCOLL, David , HOWIE, David , DARLING, Ramsay , MCLAREN, James
IPC分类号： G01N33/543
CPC分类号： C12Q1/006 , G01N33/526
摘要： An analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (e.g., a whole blood sample) includes a first and second capillary sample-receiving chambers and first and second stop junctions that are disposed between the first and second capillary sample-receiving chambers. The first stop junction defines a discontinuity boundary of the first capillary sample-receiving chamber and the second stop junction defines a discontinuity boundary of the second capillary sample-receiving chamber. In addition, the first stop junction and the second stop junction are disposed such that bodily fluid sample flow between the first capillary sample-receiving chamber and the second capillary sample-receiving chamber during use of the analytical test strip is prevented.
摘要翻译：用于测定体液样品（例如全血样品）中的分析物（例如葡萄糖）的分析测试条包括第一和第二毛细管样品接收室以及设置在第一和第二毛细管样品接收室之间的第一和第二停止接头和第二毛细管样品接收室。第一停止接头限定第一毛细管样品接收室的不连续边界，并且第二停止接头限定第二毛细管样品接收室的不连续边界。此外，第一停止接点和第二停止接点被布置成使得在使用分析测试条期间，体液样本在第一毛细管样品接收室和第二毛细管样品接收室之间流动。

2. 发明申请

WO2015197643A1 ANALYTICAL TEST STRIP WITH TIERED CAPILLARY CHAMBER 审中-公开
标题翻译：分层毛细管分析测试条
公开(公告)号：WO2015197643A1
公开(公告)日：2015-12-30
申请号：PCT/EP2015/064149
申请日：2015-06-23
申请人： LIFESCAN SCOTLAND LIMITED
发明人： SLOSS, Scott , WHYTE, Lynsey , SMITH, Antony , MCCOLL, David
IPC分类号： G01N27/327
CPC分类号： G01N33/66 , B01L3/502715 , B01L2300/0645 , B01L2300/0825 , B01L2300/0838 , B01L2300/0861 , B01L2300/0887 , G01N27/3272 , G01N27/3275 , G01N33/80 , Y10T436/144444
摘要： An analytical test strip for the determination of an analyte (such as glucose) in, or a characteristic of, a bodily fluid sample includes an electrically-insulating base layer, a first patterned spacer layer disposed on the electrically-insulating base layer, a second patterned spacer layer disposed on the first patterned spacer layer; and a top hydrophilic layer disposed on the second patterned spacer layer. In addition, the electrically-insulating base layer, the first and second patterned spacer layers and the top hydrophilic layer define a tiered capillary chamber(s) that has a first tiered capillary chamber portion defined in the first patterned spacer layer and a second tiered capillary chamber portion defined in the second patterned spacer layer. Moreover, the first tiered capillary chamber portion and the second tiered capillary chamber portion are in direct fluidic communication with one another.
摘要翻译：用于测定体液样品中的分析物（例如葡萄糖）或其特性的分析测试条包括电绝缘基层，设置在电绝缘基层上的第一图案化间隔层，第二设置在第一图案化间隔层上的图案间隔层; 以及设置在第二图案化间隔层上的顶部亲水层。此外，电绝缘基底层，第一和第二图案化间隔层和顶部亲水层限定了分层毛细管腔室，其具有限定在第一图案化间隔层中的第一分层毛细管室部分和第二分层毛细管限定在第二图案化间隔层中的腔室部分。此外，第一分层毛细管腔室部分和第二分层毛细管腔室部分彼此直接流体连通。

3. 发明申请

WO2013045952A1 ANALYTICAL TEST STRIP WITH ISOLATED BODILY FLUID PHASE-SHIFT AND ANALYTE DETERMINATION SAMPLE CHAMBERS 审中-公开
标题翻译：分离体液相分析仪和分析测定样品分析仪的分析测试条
公开(公告)号：WO2013045952A1
公开(公告)日：2013-04-04
申请号：PCT/GB2012/052425
申请日：2012-10-01
申请人： LIFESCAN SCOTLAND LIMITED , McCOLL, David , SMITH, Antony , WHYTE, Lynsey , WHITEHEAD, Neil , DARLING, Ramsay
发明人： McCOLL, David , SMITH, Antony , WHYTE, Lynsey , WHITEHEAD, Neil , DARLING, Ramsay
IPC分类号： G01N27/327
CPC分类号： G01N27/3272
摘要： An analytical test strip ("ATS") for use with a hand-held test meter in the determination of an analyte in a bodily fluid sample includes an electrically insulting substrate (102), a first patterned conductor layer (104) disposed on the electrically insulating substrate and having a working electrode (128a, 128b) and a reference electrode (130). The ATS also includes an enzymatic reagent layer (106) disposed on the working electrode, a first patterned spacer layer (108) disposed over the first patterned conductor layer and defining both a first sample-receiving channel (112) and an analyte determination sample chamber (114) within the ATS, and a second patterned spacer layer (110) disposed over the first patterned spacer layer and defining at least a second sample-receiving channel (120). The ATS further includes a bodily fluid phase-shift sample chamber (116) in fluidic communication with the second sample-receiving channel. The first sample-receiving channel (112) and analyte determination sample chamber (114) are isolated from the second sample-receiving channel (120) and bodily fluid phase-shift sample chamber (116).
摘要翻译：在用于测定体液样品中的分析物的手持测试仪中使用的分析测试条（“ATS”）包括电绝缘基底（102），设置在电液体上的第一图案化导体层（104）绝缘基板并具有工作电极（128a，128b）和参考电极（130）。 ATS还包括设置在工作电极上的酶试剂层（106），设置在第一图案化导体层之上的第一图案化间隔层（108），并且限定第一样品接收通道（112）和分析物确定样品室（114），以及设置在所述第一图案化间隔层上并且限定至少第二样品接收通道（120）的第二图案化间隔层（110）。 ATS还包括与第二样品接收通道流体连通的体液相移样品室（116）。第一样品接收通道（112）和分析物确定样品室（114）与第二样品接收通道（120）和体液相移样品室（116）隔离。

4. 发明申请

WO2013098565A1 ACCURATE ANALYTE MEASUREMENTS FOR ELECTROCHEMICAL TEST STRIP BASED ON SENSED PHYSICAL CHARACTERISTIC(S) OF THE SAMPLE CONTAINING THE ANALYTE AND DERIVED BIOSENSOR PARAMETERS 审中-公开
标题翻译：基于包含分析仪和衍生生物传感器参数的样品的感官物理特性的电化学测试条的精确分析测量
公开(公告)号：WO2013098565A1
公开(公告)日：2013-07-04
申请号：PCT/GB2012/053279
申请日：2012-12-28
申请人： LIFESCAN SCOTLAND LIMITED
发明人： MALECHA, Michael , SMITH, Antony , MCCOLL, David
IPC分类号： G01N27/327
CPC分类号： G01N27/3274 , G01N27/26 , G01N27/3272 , G06F19/24
摘要： Various embodiments for a method that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic, typically hematocrit, of the sample containing the analyte and deriving from this characteristic a parameter relating to the biosensor to attain accurate glucose concentration.
摘要翻译：用于通过确定含有分析物的样品的至少一种物理特性（通常为血细胞比容）并且从该特征导出与生物传感器相关的参数以获得精确的葡萄糖浓度来允许通过生物传感器更准确地分析物浓度的方法的各种实施方案。

5. 发明申请

WO2013098563A1 ACCURATE ANALYTE MEASUREMENTS FOR ELECTROCHEMICAL TEST STRIP BASED ON SENSED PHYSICAL CHARACTERISTIC(S) OF THE SAMPLE CONTAINING THE ANALYTE 审中-公开
标题翻译：基于包含分析仪的样品的感官物理特性的电化学测试条的精确分析测量
公开(公告)号：WO2013098563A1
公开(公告)日：2013-07-04
申请号：PCT/GB2012/053276
申请日：2012-12-28
申请人： LIFESCAN SCOTLAND LIMITED
发明人： SMITH, Antony , MALECHA, Michael , McCOLL, David
IPC分类号： G01N27/327
CPC分类号： G01N27/3274 , G01N27/26 , G01N27/3272 , G06F19/24
摘要： Glucose concentration determination with a biosensor by determining at least one physical characteristic of the blood sample, typically hematocrit percentage, and deriving one of a batch slope, a sampling time, or combinations thereof to attain glucose concentration.
摘要翻译：通过确定血液样品的至少一种物理特性（通常为血细胞比容百分比），得出批次斜率，采样时间或其组合中的一种以获得葡萄糖浓度，通过生物传感器测定葡萄糖浓度。

6. 发明申请

WO2016046344A1 ACCURATE ANALYTE MEASUREMENTS FOR ELECTROCHEMICAL TEST STRIP TO DETERMINE ANALYTE MEASUREMENT TIME BASED ON MEASURED TEMPERATURE, PHYSICAL CHARACTERISTIC AND ESTIMATED ANALYTE VALUE 审中-公开
标题翻译：基于测量温度，物理特性和估计分析值的电化学测试条的精确分析测量确定分析仪测量时间
公开(公告)号：WO2016046344A1
公开(公告)日：2016-03-31
申请号：PCT/EP2015/072040
申请日：2015-09-24
申请人： LIFESCAN SCOTLAND LIMITED
发明人： MCCOLL, David , SMITH, Antony
IPC分类号： G01N27/327
CPC分类号： G01N27/3274 , G01N27/3272 , G01N27/3273
摘要： Various embodiments for a method that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic signal representative of the sample containing the analyte and selecting an analyte measurement sampling time based on measured temperature, physical characteristic and estimated analyte values.
摘要翻译：用于通过确定代表含有分析物的样品的至少一个物理特征信号并基于测量的温度，物理特性和估计的分析物值来选择分析物测量取样时间的方法的各种实施方案，其允许通过生物传感器获得更准确的分析物浓度。

7. 发明申请

WO2013190270A1 ANALYTICAL TEST STRIP WITH CAPILLARY SAMPLE-RECEIVING CHAMBERS SEPARATED BY A PHYSICAL BARRIER ISLAND 审中-公开
标题翻译：带有毛细管样本接收板的分析测试条由物理障碍物岛分离
公开(公告)号：WO2013190270A1
公开(公告)日：2013-12-27
申请号：PCT/GB2013/051552
申请日：2013-06-13
申请人： LIFESCAN SCOTLAND LIMITED
发明人： WHYTE, Lynsey , SLOSS, Scott , MCCOLL, David , WHITEHEAD, Neil , SMITH, Antony
IPC分类号： B01L3/00 , G01N27/327
CPC分类号： G01N27/3272 , B01L3/502 , B01L2300/0825 , G01N27/3274 , G01N33/492
摘要： An analytical test strip for the determination of an analyte (such as glucose and/or hematocrit) in a bodily fluid sample (such as a whole blood sample) includes a first capillary sample-receiving chamber, a second capillary sample-receiving chamber, and a physical barrier island disposed between the first and second capillary sample-receiving chambers. Moreover, the physical island barrier is disposed such that bodily fluid sample flow between the first capillary sample-receiving chamber and the second capillary sample-receiving chamber is prevented during use of the analytical test strip.
摘要翻译：用于测定体液样品（例如全血样品）中的分析物（例如葡萄糖和/或血细胞比容）的分析测试条包括第一毛细管样品接收室，第二毛细管样品接收室和设置在第一和第二毛细管样品接收室之间的物理屏障岛。此外，物理岛屏障设置成在分析测试条的使用期间防止了体液样品在第一毛细管样品接收室和第二毛细管样品接收室之间流动。

8. 发明申请

WO2013190072A1 ELECTROCHEMICAL-BASED ANALYTICAL TEST STRIP WITH INTERSECTING SAMPLE-RECEIVING CHAMBERS 审中-公开
标题翻译：基于电化学分析测试条带接口采样样品
公开(公告)号：WO2013190072A1
公开(公告)日：2013-12-27
申请号：PCT/EP2013/062950
申请日：2013-06-20
申请人： LIFESCAN SCOTLAND LIMITED
发明人： WHYTE, Lynsey , SLOSS, Scott , WHITEHEAD, Neil , MCCOLL, David , SMITH, Antony
IPC分类号： C12Q1/00
CPC分类号： G01N27/327 , C12Q1/004 , C12Q1/006
摘要： An electrochemical-based analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (for example, a whole blood sample) and/or a characteristic of the bodily fluid sample (for example, hematocrit) includes a first sample-receiving chamber with first and second sample-application openings, and first and second electrodes. The first and second electrodes are disposed in the first sample-receiving chamber between the first and second sample-application openings. The electrochemical-based analytical test strip also includes a second sample-receiving chamber and a plurality of electrodes disposed in the second sample-receiving chamber. In addition, the second sample-receiving chamber intersects the first sample-receiving chamber between the first and second electrodes, thereby defining a chamber intersection.
摘要翻译：用于测定体液样品（例如全血样品）中的分析物（例如葡萄糖）和/或体液样品的特性（例如，血细胞比容）的基于电化学的分析测试条包括第一样品接收室，其具有第一和第二样品施加开口，以及第一和第二电极。第一和第二电极设置在第一和第二样品施加开口之间的第一样品接收室中。基于电化学的分析测试条还包括第二样品接收室和设置在第二样品接收室中的多个电极。此外，第二样本接收室在第一和第二电极之间与第一样本接收室相交，由此限定腔室交叉。

9. 发明申请

WO2013030375A1 Hematocrit Corrected Glucose Measurements for Electrochemical Test Strip Using Time Differential of the Signals 审中-公开
标题翻译：血细胞比容校正葡萄糖测量电化学测试条使用信号的时间差异
公开(公告)号：WO2013030375A1
公开(公告)日：2013-03-07
申请号：PCT/EP2012/067028
申请日：2012-08-31
申请人： LIFESCAN SCOTLAND LIMITED , MCCOLL, David , SMITH, Antony , FARMAHAN, Mandip
发明人： MCCOLL, David , SMITH, Antony , FARMAHAN, Mandip
IPC分类号： G01N27/327
CPC分类号： G01N27/3274
摘要： Various embodiments that allow for determination of hematocrit by a time differential between the input and output signals such that a glucose measurement for a blood sample can be corrected by the measured hematocrit of the blood sample.
摘要翻译：允许通过输入和输出信号之间的时间差确定血细胞比容的各种实施例，使得可以通过测量的血液样本的血细胞比容校正血液样本的葡萄糖测量。

10. 发明申请

WO2013030369A1 HEMATOCRIT CORRECTED GLUCOSE MEASUREMENTS USING PHASE ANGLES AND IMPEDANCE FOR ELECTROCHEMICAL TEST STRIP 审中-公开
标题翻译：使用相位角测定的校正葡萄糖测量值和电化学测试条带的阻抗
公开(公告)号：WO2013030369A1
公开(公告)日：2013-03-07
申请号：PCT/EP2012/067020
申请日：2012-08-31
申请人： LIFESCAN SCOTLAND LIMITED , MCCOLL, David , FARMAHAN, Mandip , SMITH, Antony
发明人： MCCOLL, David , FARMAHAN, Mandip , SMITH, Antony
IPC分类号： G01N27/327
CPC分类号： G01N27/416 , G01N27/3274
摘要： Two techniques of determining hematocrit using impedance and phase angle to determine hematocrit are shown and described for correcting an analyte concentration.
摘要翻译：显示和描述了用于校正分析物浓度的两种使用阻抗和相位角确定血细胞比容以确定血细胞比容的技术。

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