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    • 1. 发明申请
    • STENT
    • US20110022151A1
    • 2011-01-27
    • US12898815
    • 2010-10-06
    • Kyong-Min SHINDong-Il Gwon
    • Kyong-Min SHINDong-Il Gwon
    • A61F2/82
    • A61F2/04A61F2/852A61F2002/041A61F2230/0067A61F2250/0039
    • If smooth transportation of bile toward the duodenum is difficult due to cancerous cells growing in the bile duct or due to stricture of the bile duct, a cylindrical stent may be implanted into the stenosed site of the bile duct to enable smooth supply of bile. Conventional stents have no risk of slippage at an implanted position thereof, but suffer from invasively growing cancerous cells. Although a covered stent having a coating has been proposed to solve invasion of the growing cancerous cells, the covered stent may have a risk of slippage at an implanted position thereof and also, may cause pancreatitis and cholelithiasis. To solve the above described problems, disclosed herein is a stent to prevent backflow of food from the duodenum to the bile duct while assuring smooth transportation of bile without a risk of unwanted displacement caused by the transported bile. The stent includes a cylindrical outer stent, and a downwardly tapered inner stent covered with a polytetrafluoroethylene (PTFE) or silicone coating having biocompatibility. The inner and outer stents are coupled to each other to define a double structure.
    • 如果胆汁向十二指肠顺利运输是困难的,因为胆管内生长的癌细胞或胆管狭窄,可以将圆柱形支架植入胆管狭窄部位,以使胆汁平稳供应。 常规的支架在其植入位置没有滑动的风险,但遭受侵袭性生长的癌细胞。 虽然已经提出了具有涂层的覆盖支架来解决生长中的癌细胞的侵袭,但是所覆盖的支架可能在其植入位置处具有滑动的风险,并且还可能引起胰腺炎和胆石病。 为了解决上述问题,本文公开了一种用于防止食物从十二指肠向胆管回流的支架,同时确保胆汁的平稳运输,而不会由于运输的胆汁引起不希望的位移。 支架包括圆柱形外支架和用聚四氟乙烯(PTFE)或具有生物相容性的硅氧烷涂层覆盖的向下锥形内支架。 内支架和外支架彼此连接以限定双重结构。
    • 4. 发明申请
    • STENT FOR CONNECTING ADJACENT TISSUES OF ORGANS
    • 用于连接器官的相邻组织
    • US20130012969A1
    • 2013-01-10
    • US13542412
    • 2012-07-05
    • Kyong-Min SHIN
    • Kyong-Min SHIN
    • A61B17/11
    • A61F2/064A61B17/11A61B17/1114A61B2017/00862A61B2017/00867A61B2017/00995A61B2017/1139A61F2/90
    • Disclosed herein is a stent for connecting adjacent tissues of the organs of a patient. The stent includes a hollow cylindrical body which is formed by weaving a superelastic shape-memory alloy wire in an overlapping manner such that rhombic openings are formed, and wing parts which are provided by expanding respective opposite ends of the hollow cylindrical body outwards and turning the opposite ends inside out on bent portions. The wing parts face each other so that the wing parts are tensed in a longitudinal direction of the cylindrical body. Thereby, the wing parts can elastically move inwards or outwards with respect to the longitudinal direction to automatically adjust a distance between the wing parts in response to the distance between the adjacent tissues of the organs or thicknesses of walls of the organs, so that the wing parts are put into close contact with the adjacent tissues.
    • 本文公开了一种用于连接患者器官的相邻组织的支架。 支架包括中空圆柱体,其通过以重叠的方式编织超弹性形状记忆合金线而形成,使得形成菱形开口,以及翼部,其通过将中空圆柱体的相应的相对端向外扩展并将 弯曲部分的内侧的相对端部。 翼部彼此面对,使得翼部在圆柱体的纵向方向上被拉紧。 因此,翼部件能够相对于纵向方向弹性地向内或向外移动,以响应于器官的相邻组织之间的距离或器官的壁的厚度来自动调整翼部之间的距离,使得翼 零件与相邻的纸巾紧密接触。
    • 5. 发明申请
    • METHOD OF MANUFACTURING COATING AGENT FOR DRUG RELEASING STENT AND COATING AGENT FOR DRUG RELEASING STENT MANUFACTURED THEREBY
    • 制造用于药物释放的涂层剂的方法和用于药物释放的涂层剂
    • US20120316127A1
    • 2012-12-13
    • US13491145
    • 2012-06-07
    • Kyong-Min SHINKun Na
    • Kyong-Min SHINKun Na
    • A61K31/7068A61P35/00B05D5/00
    • A61L31/16A61L31/10A61L2300/416A61L2300/608A61L2420/02C08L75/04C08L27/18
    • This invention relates to a method of manufacturing a coating agent for a drug releasing stent and to a coating agent for a drug releasing stent manufactured thereby. This method includes (1) dissolving polyurethane in tetrahydrofuran, (2) dissolving pluronic F-127 in tetrahydrofuran, (3) dissolving a gemcitabine compound in ethanol, (4) mixing these three solutions obtained in (1) to (3) thus preparing a solution mixture, (5) applying the solution mixture obtained in (4) on a stent coated with a Teflon film, (6) drying the stent of (5) for a predetermined period of time and then immersing the stent in a polyurethane solution in tetrahydrofuran, and (7) removing the stent immersed in (6) from the polyurethane solution and then drying the stent, so that the rate of release of an anti-cancer drug applied on the stent can be continuously and maximally improved thereby maximizing anti-cancer efficacy.
    • 本发明涉及一种制造药物释放支架用涂布剂的方法及其制造的药物释放支架用涂布剂。 该方法包括(1)将聚氨酯溶于四氢呋喃中,(2)将普鲁尼克F-127溶解在四氢呋喃中,(3)将吉西他滨化合物溶于乙醇中,(4)将(1)至(3)中得到的三种溶液混合, 溶液混合物,(5)将(4)中得到的溶液混合物涂布在涂有特氟龙膜的支架上,(6)将(5)的支架干燥规定时间,然后将支架浸渍在聚氨酯溶液 在四氢呋喃中,和(7)从聚氨酯溶液中取出浸没在(6)中的支架,然后干燥支架,使得施加在支架上的抗癌药物的释放速率可以连续和最大程度地提高,从而最大化抗 - 功效
    • 7. 发明申请
    • PLASTIC STENT AND STENT OPERATION APPARATUS FOR THE SAME
    • 塑料手柄和固定装置操作装置
    • US20110282429A1
    • 2011-11-17
    • US13095452
    • 2011-04-27
    • Kyong-Min SHINByung-Cheol Myung
    • Kyong-Min SHINByung-Cheol Myung
    • A61F2/82
    • A61F2/04A61F2/94A61F2/95A61F2002/041A61F2002/9505
    • Disclosed herein are a plastic stent and a stent operation apparatus for plastic stents. The plastic stent includes a stent body with a flow hole formed through the stent body in the longitudinal direction thereof. The stent operation apparatus includes a stent push rod having an externally threaded end. The stent body has an internal thread on the circumferential inner surface of the flow hole so that the internal thread engages with the externally threaded end of the stent push rod of the stent operation apparatus. The plastic stent is coupled to the stent push rod by the threaded engagement between the externally threaded end and the internal thread, is inserted into the body of a patient, is adjusted in location by pushing or pulling the stent push rod, and is released from the stent push rod at a correct location in the body of the patient by disengaging the threaded engagement.
    • 本文公开了一种用于塑料支架的塑料支架和支架操作装置。 塑料支架包括具有在其长度方向上穿过支架主体形成的流动孔的支架体。 支架操作装置包括具有外螺纹端的支架推杆。 支架主体在流动孔的周向内表面上具有内螺纹,使得内螺纹与支架操作装置的支架推杆的外螺纹端接合。 塑料支架通过外螺纹端和内螺纹之间的螺纹接合被连接到支架推杆,插入到患者体内,通过推动或拉动支架推杆来调节位置,并从 支架推杆在患者身体的正确位置脱离接合线。
    • 9. 发明申请
    • METHOD OF MANUFACTURING ANTI-MIGRATION STENT AND STENT MANUFACTURED THEREBY
    • 制造抗转移手段的方法及其制造方法
    • US20160106559A1
    • 2016-04-21
    • US14860424
    • 2015-09-21
    • Kyong-Min SHINTAEWOONG MEDICAL CO., LTD.
    • Kyong-Min SHINYoung ill HONG
    • A61F2/86
    • A61F2/90A61F2002/8486A61F2230/0069A61F2240/001
    • An anti-migration stent includes a hollow stent body formed by interweaving a superelastic shape memory alloy wire diagonally such that upper and lower wires alternately cross over and under each other, forming multiple diamond-shaped spaces. After placing and holding a rod underneath the wire of the hollow stent body, and heating the stent body, an anti-migration bent part is formed on the wire, protruding vertically to form an outline corresponding to a cross-sectional shape of the rod, which makes stent production easy. The stent is prevented from migrating in a lumen of a human body by the bent part protruding vertically and diagonally from the stent body, and easy to insert into and remove from the lumen, preventing the conventional problem damaging an inner surface of the lumen.
    • 抗迁移支架包括通过对角地交织超弹性形状记忆合金线形成的中空支架体,使得上下电线交替地交叉并彼此相交,形成多个菱形空间。 在将中空支架体的线材放置并保持杆体并加热支架主体之后,在线材上形成防偏移弯曲部分,垂直突出以形成对应于杆的截面形状的轮廓, 这使得支架生产变得容易。 通过从支架主体垂直和对角突出的弯曲部分,能够防止在内腔内迁移支架,并且容易插入内窥镜和从内腔移除,从而防止传统问题损害内腔内表面。