专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09453066B2 FC binding protein and method for manufacturing same 有权
标题翻译： FC结合蛋白及其制造方法
公开(公告)号：US09453066B2
公开(公告)日：2016-09-27
申请号：US13583550
申请日：2011-03-10
申请人： Kouta Hatayama , Yoshiharu Asaoka , Toru Tanaka , Teruhiko Ide
发明人： Kouta Hatayama , Yoshiharu Asaoka , Toru Tanaka , Teruhiko Ide
IPC分类号： C07K1/00 , A23J1/00 , C07K14/735 , C07K1/22 , C07K17/08 , C07K16/00
CPC分类号： C07K14/70535 , C07K1/22 , C07K17/08 , C07K2319/21
摘要： Disclosed are: an Fc binding protein having increased stability with respect to heat, acid, and/or alkalinity compared with the wild type; a method for producing same; and a method for specifically isolating protein containing an Fc binding protein binding site using said Fc binding protein as a ligand for affinity chromatography.An Fc binding protein was obtained having increased stability with respect to heat, acid, and/or alkalinity compared with the wild-type human Fc receptor by means of substituting at least one specific amino acid residue in the extracellular domain of the wild-type human Fc receptor with another amino acid residue. The Fc binding protein is useful as a ligand for affinity chromatography for example by immobilizing in a solid phase. Also, when the Fc binding protein is expressed using a host that has been transformed with an expression vector containing a polynucleotide coding for said protein, the amount of produced protein is increased compared with using a wild-type human Fc receptor.
摘要翻译：获得了与野生型人Fc受体相比，通过用野生型人细胞外结构域中的至少一个特定氨基酸残基取代的具有相对于热，酸和/或碱度的稳定性增加的Fc结合蛋白质 Fc受体与另一个氨基酸残基。 Fc结合蛋白可用作亲和层析的配体，例如通过固定在固相中。此外，当使用已经用含有编码所述蛋白质的多核苷酸的表达载体转化的宿主来表达Fc结合蛋白时，与使用野生型人Fc受体相比，产生的蛋白质的量增加。

2. 发明申请

US20130079499A1 FC BINDING PROTEIN AND METHOD FOR MANUFACTURING SAME 有权
标题翻译： FC结合蛋白及其制造方法
公开(公告)号：US20130079499A1
公开(公告)日：2013-03-28
申请号：US13583550
申请日：2011-03-10
申请人： Kouta Hatayama , Yoshiharu Asaoka , Toru Tanaka , Teruhiko Ide
发明人： Kouta Hatayama , Yoshiharu Asaoka , Toru Tanaka , Teruhiko Ide
IPC分类号： C07K14/735 , C07K17/08 , C07K1/22
CPC分类号： C07K14/70535 , C07K1/22 , C07K17/08 , C07K2319/21
摘要： Disclosed are: an Fc binding protein having increased stability with respect to heat, acid, and/or alkalinity compared with the wild type; a method for producing same; and a method for specifically isolating protein containing an Fc binding protein binding site using said Fc binding protein as a ligand for affinity chromatography.An Fc binding protein was obtained having increased stability with respect to heat, acid, and/or alkalinity compared with the wild-type human Fc receptor by means of substituting at least one specific amino acid residue in the extracellular domain of the wild-type human Fc receptor with another amino acid residue. The Fc binding protein is useful as a ligand for affinity chromatography for example by immobilizing in a solid phase. Also, when the Fc binding protein is expressed using a host that has been transformed with an expression vector containing a polynucleotide coding for said protein, the amount of produced protein is increased compared with using a wild-type human Fc receptor.
摘要翻译：公开了：与野生型相比，相对于热，酸和/或碱度具有增加的稳定性的Fc结合蛋白; 其制造方法; 以及使用所述Fc结合蛋白作为亲和层析的配体来特异性分离含有Fc结合蛋白结合位点的蛋白质的方法。获得了与野生型人Fc受体相比，通过用野生型人细胞外结构域中的至少一个特定氨基酸残基取代的具有相对于热，酸和/或碱度的稳定性增加的Fc结合蛋白 Fc受体与另一个氨基酸残基。 Fc结合蛋白可用作亲和层析的配体，例如通过固定在固相中。此外，当使用已经用含有编码所述蛋白质的多核苷酸的表达载体转化的宿主来表达Fc结合蛋白时，与使用野生型人Fc受体相比，产生的蛋白质的量增加。

3. 发明授权

US08569014B2 Microorganism and method for producing canthaxanthin 失效
标题翻译：微生物和生产角黄素的方法
公开(公告)号：US08569014B2
公开(公告)日：2013-10-29
申请号：US13206999
申请日：2011-08-10
申请人： Toru Tanaka , Teruhiko Ide
发明人： Toru Tanaka , Teruhiko Ide
IPC分类号： C12P23/00
CPC分类号： C12R1/01 , C12P23/00
摘要： A carotenoid producing bacterium belonging to the genus Paracoccus that selectively produces canthaxanthin so that the amount thereof is not less than 90 percent by weight of the total amount of produced carotenoids including β-carotene, β-cryptoxanthin, echinenone, canthaxanthin, 3-hydroxyechinenone, 3′-hydroxyechinenone, zeaxanthin, phoenicoxanthin, adonixanthin, and astaxanthin. A method for producing canthaxanthin by culturing the above bacterium, and then collecting carotenoids from bacterial cells or a culture solution after the culturing.
摘要翻译：属于副球菌属的产生类胡萝卜素的细菌选择性地生产角黄素，其量不小于包含β-胡萝卜素，β-隐黄质，海参酮，角黄素，3-羟基喹喔啉酮的生产类胡萝卜素总量的90重量％ 3'-羟基喹喔啉酮，玉米黄质，磷酸黄嘌呤，亚二黄素和虾青素。通过培养上述细菌生产角黄素的方法，然后在培养后从细菌细胞或培养液中收集类胡萝卜素。

4. 发明授权

US08883969B2 Method for production of carotenoid-synthesizing microorganism and method for production of carotenoid 有权
标题翻译：类胡萝卜素合成微生物的生产方法及类胡萝卜素生产方法
公开(公告)号：US08883969B2
公开(公告)日：2014-11-11
申请号：US12089486
申请日：2006-09-25
申请人： Teruhiko Ide , Toru Tanaka
发明人： Teruhiko Ide , Toru Tanaka
IPC分类号： C07K14/00 , A23L1/275 , C12P23/00 , A23K1/16 , C12N15/74
CPC分类号： C12P23/00 , A23K20/179 , A23L5/44 , C12N15/743
摘要： A method for producing a carotenoid comprising the steps of cultivating a cell transformed with a DNA sequence comprising a DNA sequence depicted in anyone of SEQ ID NOs: 2-7 or a cell transformed with a vector having a DNA sequence depicted in anyone of SEQ ID NOs: 2-7 under proper culture conditions and isolating the carotenoid from the cell or the culture.
摘要翻译：一种制备类胡萝卜素的方法，包括以下步骤：培养用包含SEQ ID NO：2-7中任一个所示的DNA序列的DNA序列转化的细胞，或用SEQ ID NO：2-7中任一个所示DNA片段的载体转化的细胞 NOS：2-7在适当的培养条件下，从细胞或培养物中分离类胡萝卜素。

5. 发明授权

US08030022B2 Microorganism and method for producing carotenoid using it 有权
标题翻译：微生物和使用它生产类胡萝卜素的方法
公开(公告)号：US08030022B2
公开(公告)日：2011-10-04
申请号：US12095511
申请日：2006-10-19
申请人： Toru Tanaka , Teruhiko Ide
发明人： Toru Tanaka , Teruhiko Ide
IPC分类号： C12P23/00
CPC分类号： C12R1/01 , C12P23/00
摘要： A carotenoid producing bacterium belonging to the genus Paracoccus that selectively produces canthaxanthin so that the amount thereof is not less than 90 percent by weight of the total amount of produced carotenoids including β-carotene, β-cryptoxanthin, echinenone, canthaxanthin, 3-hydroxyechinenone, 3′-hydroxyechinenone, zeaxanthin, phoenicoxanthin, adonixanthin, and astaxanthin. A method for producing canthaxanthin by culturing the above bacterium, and then collecting carotenoids from bacterial cells or a culture solution after the culturing.
摘要翻译：属于副球菌属的类胡萝卜素生产菌选择性地生产角黄素，使其量不少于生产的类胡萝卜素总量的90％（重量），包括胡萝卜素，苦参碱，氢化chin酮，角黄素，3- 羟基ech en酮，3'-羟基ech in酮，玉米黄质，磷酸黄嘌呤，洋ix素和虾青素。通过培养上述细菌生产角黄素的方法，然后在培养后从细菌细胞或培养液中收集类胡萝卜素。

6. 发明申请

US20100285524A1 NOVEL MICROORGANISM AND METHOD FOR PRODUCING CAROTENOID USING THE SAME 有权
标题翻译：新型微生物及其制造方法
公开(公告)号：US20100285524A1
公开(公告)日：2010-11-11
申请号：US12095511
申请日：2006-10-19
申请人： Toru Tanaka , Teruhiko Ide
发明人： Toru Tanaka , Teruhiko Ide
IPC分类号： C12P23/00 , C12N1/20 , C12N1/21
CPC分类号： C12R1/01 , C12P23/00
摘要： [Object] To provide a canthaxanthin selective producing bacterium being able to easily extract and purify canthaxanthin, which is one of carotenoids, and a method for producing canthaxanthin by a culture method.[Solving Means] A carotenoid producing bacterium belonging to the genus Paracoccus is provided which selectively produces canthaxanthin so that the amount thereof is not less than 90 percent by weight of the total amount of produced carotenoids including β-carotene, β-cryptoxanthin, echinenone, canthaxanthin, 3-hydroxyechinenone, 3′-hydroxyechinenone, zeaxanthin, phoenicoxanthin, adonixanthin, and astaxanthin. In addition, a method for producing canthaxanthin is provided which has the steps of culturing the above bacterium, and then collecting carotenoids from bacterial cells or a culture solution after the culturing.
摘要翻译：本发明提供能够容易地提取和纯化作为类胡萝卜素的角黄素的角黄素选择性生产菌，以及通过培养方法制备角黄素的方法。 [解决方案]提供属于副球菌属的类胡萝卜素生产细菌，其选择性地产生角黄素，其量不小于包含“胡萝卜素”，“副霉黄素”的生产的类胡萝卜素总量的90重量％海参酮，角黄素，3-羟基喹喔啉酮，3'-羟基喹喔啉酮，玉米黄质，磷酸黄嘌呤，亚二黄素和虾青素。此外，提供了一种生产角黄素的方法，其具有培养上述细菌的步骤，然后在培养后从细菌细胞或培养液中收集类胡萝卜素。

7. 发明授权

US08221997B2 Microorganism and method for producing carotenoid using the same 有权
标题翻译：微生物和使用其制备类胡萝卜素的方法
公开(公告)号：US08221997B2
公开(公告)日：2012-07-17
申请号：US12089451
申请日：2006-09-26
申请人： Toru Tanaka , Teruhiko Ide , Kei-ichi Murayama , Seigou Oe , Toru Imaizumi , Satoshi Hanzawa , Toshinobu Toyoshima
发明人： Toru Tanaka , Teruhiko Ide , Kei-ichi Murayama , Seigou Oe , Toru Imaizumi , Satoshi Hanzawa , Toshinobu Toyoshima
IPC分类号： C12P23/00 , C12N1/20 , C12N1/38
CPC分类号： C12R1/01 , C12P23/00
摘要： To provide a microorganism capable of producing a large amount of carotenoids, mainly astaxanthin, and to provide a method of producing carotenoids using the microorganism, a microorganism having improved carotenoid productivity is used, which is obtainable by breeding a carotenoid producing Paracoccus bacteria which is featured by producing 720 mg or more carotenoid per 1 L of culture medium. Also used is a method of producing carotenoids using the bacterium.
摘要翻译：为了提供能够产生大量类胡萝卜素（主要是虾青素）的微生物，并且提供使用该微生物生产类胡萝卜素的方法，使用具有改善的类胡萝卜素生产率的微生物，其可通过育种产生类胡萝卜素的副球菌获得通过每1升培养基产生720mg以上的类胡萝卜素。还使用了使用细菌生产类胡萝卜素的方法。

8. 发明申请

US20090226582A1 METHOD FOR PRODUCTION OF CAROTENOID-SYNTHESIZING MICROORGANISM AND METHOD FOR PRODUCTION OF CAROTENOID 有权
公开(公告)号：US20090226582A1
公开(公告)日：2009-09-10
申请号：US12089486
申请日：2006-09-25
申请人： Teruhiko Ide , Toru Tanaka
发明人： Teruhiko Ide , Toru Tanaka
IPC分类号： A23L1/30 , C12P23/00 , C12N15/11 , C12N15/00 , C12N1/21
CPC分类号： C12P23/00 , A23K20/179 , A23L5/44 , C12N15/743
摘要： A microorganism is provided which allows carotenoid production in industrial production scale. A method of preparing a carotenoid includes: culturing a cell transformed with a DNA chain having a DNA sequence selected from the group consisting of the following (a) to (f) or a cell transformed with a vector having a DNA sequence selected from the group consisting of the following (a) to (f) in an appropriate culture condition, and isolating carotenoid from the cell or a culture medium: (a) DNA sequence encoding a polypeptide having such an enzymatic activity of Paracoccus sp. Strain MBIC1143 that converts a methylene group at 4 position in β-ionone ring into a keto group (crtW), described in SEQ ID NO: 2, or a substantially homologous DNA sequence thereof; (b) DNA sequence encoding a polypeptide having such an enzymatic activity of Paracoccus sp. Strain MBIC1143 that adds one hydroxyl group to a carbon at 3-position of 4-keto-β-ionone ring and/or at 3-position of β-ionone ring (crtZ), described in SEQ ID NO: 3, or a substantially homologous DNA sequence thereof; (c) DNA sequence encoding a polypeptide having such an enzymatic activity of Paracoccus sp. Strain MBIC1143 that converts lycopene into β-carotene (crtY), described in SEQ ID NO: 4, or a substantially homologous DNA sequence thereof; (d) DNA sequence encoding a polypeptide having such an enzymatic activity of Paracoccus sp. Strain MBIC1143 that converts phytoene into lycopene (crtI), described in SEQ ID NO: 5, or a substantially homologous DNA sequence thereof; (e) DNA sequence encoding a polypeptide having prephytoene synthase activity of Paracoccus sp. Strain MBIC1143 (crtB), as described in SEQ ID NO: 6, or a substantially homologous DNA sequence thereof; and (f) DNA sequence encoding a polypeptide having geranylgeranyl diphosphate synthase activity of Paracoccus sp. Strain MBIC1143 (crtE), as described in SEQ ID NO: 7, or a substantially homologous DNA sequence thereof.

9. 发明申请

US20090221026A1 Novel Microorganism And Method For Producing Carotenoid Using The Same 有权
标题翻译：新型微生物及其生产类胡萝卜素的方法
公开(公告)号：US20090221026A1
公开(公告)日：2009-09-03
申请号：US12089451
申请日：2006-09-26
申请人： Toru Tanaka , Teruhiko Ide , Kei-ichi Murayama , Seigou Oe , Toru Imaizumi , Satoshi Hanzawa , Toshinobu Toyoshima
发明人： Toru Tanaka , Teruhiko Ide , Kei-ichi Murayama , Seigou Oe , Toru Imaizumi , Satoshi Hanzawa , Toshinobu Toyoshima
IPC分类号： C12P23/00 , C12N1/20 , C12N1/38
CPC分类号： C12R1/01 , C12P23/00
摘要： To provide a microorganism capable of producing a large amount of carotenoids, mainly astaxanthin, and to provide a method of producing carotenoids using the microorganism, a microorganism having improved carotenoid productivity is used, which is obtainable by breeding a carotenoid producing Paracoccus bacteria which is featured by producing 720 mg or more carotenoid per 1 L of culture medium. Also used is a method of producing carotenoids using the bacterium.
摘要翻译：为了提供能够产生大量类胡萝卜素（主要是虾青素）的微生物，并且提供使用该微生物生产类胡萝卜素的方法，使用具有改善的类胡萝卜素生产率的微生物，其可通过育种产生类胡萝卜素的副球菌获得通过每1升培养基产生720mg以上的类胡萝卜素。还使用了使用细菌生产类胡萝卜素的方法。

10. 发明授权

US09318764B2 Proton conducting polymer membrane, membrane-electrode assembly using same, and polymer electrolyte fuel cell 有权
标题翻译：质子导电聚合物膜，使用其的膜 - 电极组件和聚合物电解质燃料电池
公开(公告)号：US09318764B2
公开(公告)日：2016-04-19
申请号：US14007241
申请日：2012-04-13
申请人： Toru Tanaka , Katsutoshi Suzuki , Haruhiko Komoriya , Arata Takahashi , Saori Itabashi
发明人： Toru Tanaka , Katsutoshi Suzuki , Haruhiko Komoriya , Arata Takahashi , Saori Itabashi
IPC分类号： H01M8/10 , H01B1/12 , C08J5/22
CPC分类号： H01M8/1039 , C08J5/2225 , H01B1/122 , H01M8/1011 , H01M8/1023 , H01M8/1037 , H01M8/1053 , Y02E60/523 , Y10T156/10
摘要： Disclosed is a proton conducting polymer membrane formed by laminating a plurality of solid electrolyte membranes. This proton conducting polymer membrane is one prepared by laminating at least one layer of a solid electrolyte membrane formed by using a resin having a bis(perfluoroalkanesulfonyl)methide group in the chemical structure. This solid electrolyte membrane has a superior proton conductivity without transmitting the fuel (methanol or hydrogen).
摘要翻译：公开了通过层叠多个固体电解质膜形成的质子传导性聚合物膜。该质子传导性聚合物膜是通过层叠通过在化学结构中使用具有双（全氟烷基磺酰基）甲硅烷基的树脂形成的至少一层固体电解质膜而制备的。该固体电解质膜在不传输燃料（甲醇或氢）的情况下具有优异的质子传导性。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式