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1. 发明授权

EP2699929B1 INTERLEAVED BLACK AND BRIGHT BLOOD MRI 有权转让
公开(公告)号：EP2699929B1
公开(公告)日：2019-12-11
申请号：EP12722857.5
申请日：2012-04-12
申请人： Koninklijke Philips N.V. , Philips Intellectual Property & Standards GmbH , The University of Washington
发明人： WANG, Jinnan , CHEN, Huijun , BÖRNERT, Peter , YUAN, Chun
IPC分类号： G01R33/563

2. 发明公开

EP2699929A1 INTERLEAVED BLACK AND BRIGHT BLOOD DYNAMIC CONTRAST ENHANCED (DCE) MRI 有权转让
标题翻译：动态增强MRI隔行黑亮BLOOD
公开(公告)号：EP2699929A1
公开(公告)日：2014-02-26
申请号：EP12722857.5
申请日：2012-04-12
申请人： Koninklijke Philips N.V. , Philips Intellectual Property & Standards GmbH , The University of Washington
发明人： WANG, Jinnan , CHEN, Huijun , BÖRNERT, Peter , YUAN, Chun
IPC分类号： G01R33/563
摘要： Interleaved black/bright imaging (IBBI) is performed using a magnetic resonance (MR) scanner wherein the black blood module of the IBBI includes: applying a first flow sensitization gradient; applying a spoiler gradient after applying the first flow sensitization gradient; applying a second flow sensitization gradient after applying the spoiler gradient wherein the second flow sensitization gradient has area equal to the first flow sensitization gradient but of opposite polarity; applying a slice selective radio frequency excitation pulse after applying the spoiler gradient; and performing a MR readout after applying the second flow sensitization gradient and after applying the slice selective radio frequency excitation wherein the readout acquires MR imaging data having blood signal suppression in the region excited by the slice selective radio frequency excitation pulse. The MR imaging data having blood signal suppression is reconstructed to generate black blood images, and MR imaging data generated by bright blood modules of the IBBI is reconstructed to generate bright blood images.

3. 发明公开

EP2689261A1 COMPRESSED SENSING MR IMAGE RECONSTRUCTION USING CONSTRAINT FROM PRIOR ACQUISITION 有权转让
标题翻译：使用压缩采集由以前的限制收购MRI图像重建
公开(公告)号：EP2689261A1
公开(公告)日：2014-01-29
申请号：EP12708953.0
申请日：2012-02-28
申请人： Koninklijke Philips N.V. , Philips Intellectual Property & Standards GmbH
发明人： DONEVA, Mariya Ivanova , REMMELE, Stefanie , BÖRNERT, Peter , MAZURKEWITZ, Peter , SENEGAS, Julien , KEUPP, Jochen , NEHRKE, Kay
IPC分类号： G01R33/56 , G01R33/561 , G01R33/567 , G01R33/48
CPC分类号： G01R33/56 , G01R33/4824 , G01R33/5608 , G01R33/5611 , G01R33/56509
摘要： The invention relates to a method of MR imaging of at least a portion of a body (10) of a patient placed in an examination volume of a MR device (1), the method comprising the steps of: - subjecting the portion of the body (10) to a first imaging sequence for acquiring a first signal data set (21); - subjecting the portion of the body (10) to a second imaging sequence for acquiring a second signal data set (23), wherein the imaging parameters of the second imaging sequence differ from the imaging parameters of the first imaging sequence; - reconstructing a MR image from the second signal data set (23) by means of regularization using the first signal data set (21) as prior information. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).

4. 发明公开

EP2699930A1 BLACK BLOOD MRI USING A STIMULATED ECHO PULSE SEQUENCE WITH FLOW SENSITIZATION GRADIENTS 审中-公开
标题翻译：与STRÖMUNGSSENSIBILISIERUNGSGRADIENTEN受激回波脉冲序列的黑血MRI
公开(公告)号：EP2699930A1
公开(公告)日：2014-02-26
申请号：EP12724163.6
申请日：2012-04-12
申请人： Koninklijke Philips N.V. , Philips Intellectual Property & Standards GmbH , The University of Washington
发明人： WANG, Jinnan , BÖRNERT, Peter , YUAN, Chun
IPC分类号： G01R33/563
CPC分类号： G01R33/30 , G01R33/56316 , G01R33/5635
摘要： A black blood magnetic resonance imaging sequence is performed using a magnetic resonance scanner. The sequence includes: applying a first flow sensitization gradient; applying a spoiler gradient after applying the first flow sensitization gradient; applying a second flow sensitization gradient after applying the spoiler gradient wherein the second flow sensitization gradient has area equal to the first flow sensitization gradient but of opposite polarity; applying a slice-selective radio frequency excitation pulse after applying the spoiler gradient; and performing a magnetic resonance readout after applying the second flow sensitization gradient and after applying the slice selective radio frequency excitation. The readout acquires magnetic resonance imaging data having blood signal suppression in the region excited by the slice-selective radio frequency excitation pulse. The magnetic resonance imaging data is suitably reconstructed to generate a black blood image that may be displayed.

5. 发明申请

WO2004095048A1 MR IMAGING METHOD 审中-公开
标题翻译： MR成像方法
公开(公告)号：WO2004095048A1
公开(公告)日：2004-11-04
申请号：PCT/IB2004/050417
申请日：2004-04-13
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , EGGERS, Holger , SCHÄFFTER, Tobias , BÖRNERT, Peter
发明人： EGGERS, Holger , SCHÄFFTER, Tobias , BÖRNERT, Peter
IPC分类号： G01R33/50
CPC分类号： G01R33/56554 , G01R33/565 , G01R33/56536
摘要： The invention relates to a method for generating an MR image of an object situated in an examination volume of an MR apparatus. The method begins with the acquisition of a plurality of echo signals having at least two different echo-time values (ti, t2, t3), the echo signals being generated from high-frequency pulses and magnetic-field gradient pulses by means of an imaging sequence. An intermediate MR image (5, 6, 7) is then reconstructed for each echo-time value (ti, t2, t3). By analyzing these intermediate MR images (5, 6, 7), local relaxation times (T2*(x)) and/or local frequency shifts (Aw(x)) are determined by taking account of the respective echo-time values (t1, t2, t3). Finally, a definitive MR image (11) is reconstructed from the echo signals (1) in their entirety.
摘要翻译：本发明涉及一种用于产生位于MR装置检查体积中的物体的MR图像的方法。该方法开始于获取具有至少两个不同回波时间值（ti，t2，t3）的多个回波信号，回波信号通过成像从高频脉冲和磁场梯度脉冲产生序列。然后针对每个回波时间值（ti，t2，t3）重建中间MR图像（5,6,7）。通过分析这些中间MR图像（5,6,7），通过考虑相应的回波时间值（t1（t））来确定局部弛豫时间（T2 *（x））和/或局部频移（Aw（x），t2，t3）。最后，从回波信号（1）整体重建确定的MR图像（11）。

6. 发明申请

WO2012143824A1 INTERLEAVED BLACK AND BRIGHT BLOOD DYNAMIC CONTRAST ENHANCED (DCE) MRI 审中-公开
标题翻译：交互式BLACK和BRIGHT BLOOD动态对比增强（DCE）MRI
公开(公告)号：WO2012143824A1
公开(公告)日：2012-10-26
申请号：PCT/IB2012/051779
申请日：2012-04-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , UNIVERSITY OF WASHINGTON , WANG, Jinnan , CHEN, Huijun , BÖRNERT, Peter , YUAN, Chun
发明人： WANG, Jinnan , CHEN, Huijun , BÖRNERT, Peter , YUAN, Chun
IPC分类号： G01R33/563
CPC分类号： G01R33/48 , G01R33/56316 , G01R33/5635
摘要： Interleaved black/bright imaging (IBBI) is performed using a magnetic resonance (MR) scanner (10) wherein the black blood module (52) of the IBBI includes: applying a first flow sensitization gradient; applying a spoiler gradient after applying the first flow sensitization gradient; applying a second flow sensitization gradient after applying the spoiler gradient wherein the second flow sensitization gradient has area equal to the first flow sensitation gradient but of opposite polarity; applying a slice selective radio frequency excitation pulse after applying the spoiler gradient; and performing a MR readout after applying the second flow sensitization gradient and after applying the slice selective radio frequency excitation wherein the readout acquires MR imaging data having blood signal suppression in the region excited by the slice selective radio frequency excitation pulse. The MR imaging data having blood signal suppression is reconstructed to generate black blood images (20), and MR imaging data generated by bright blood modules (50) of the IBBI is reconstructed to generate bright blood images (22).
摘要翻译：使用磁共振（MR）扫描器（10）进行交错黑/亮成像（IBBI），其中IBBI的黑血模块（52）包括：施加第一流感敏化梯度; 在应用第一流感敏化梯度后应用扰流板梯度; 在施加扰流板梯度之后施加第二流动增感梯度，其中第二流动增感梯度具有等于第一流动感觉梯度但具有相反极性的面积; 应用扰流板梯度后应用切片选择性射频激励脉冲; 以及在应用所述第二流敏增强梯度之后并且在施加所述切片选择性射频激发之后执行MR读出，其中所述读出器获取在由所述切片选择性射频激励脉冲激发的区域中具有血液信号抑制的MR成像数据。重建具有血液信号抑制的MR成像数据以产生黑血图像（20），并重建由IBBI的亮血模块（50）产生的MR成像数据，以产生亮血图像（22）。

7. 发明申请

WO2011098941A1 CORONARY MAGNETIC RESONANCE ANGIOGRAPHY WITH SIGNAL SEPARATION FOR WATER AND FAT 审中-公开
标题翻译：具有水和脂肪信号分离的冠状磁共振血管图像
公开(公告)号：WO2011098941A1
公开(公告)日：2011-08-18
申请号：PCT/IB2011/050504
申请日：2011-02-07
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BÖRNERT, Peter , NEHRKE, Kay , DONEVA, Mariya, Ivanova
发明人： BÖRNERT, Peter , NEHRKE, Kay , DONEVA, Mariya, Ivanova
IPC分类号： G01N24/08 , G01R33/54 , G01R33/561
CPC分类号： G01R33/4828 , G01N24/082 , G01R33/4824 , G01R33/5608 , G01R33/5611 , G01R33/5614 , G01R33/5616 , G01R33/5617 , G01R33/5635
摘要： The invention relates to a method of performing coronary magnetic resonance angiography with signal separation for water and fat, the method comprising: acquiring coronary magnetic resonance angiography datasets using multi-echo Dixon acquisition, processing (314; 316; 318) the datasets for reconstruction of a first (320) and second (322) image data set, the first and second image data set comprising separate water and fat image data, wherein the processing of the datasets comprises a Dixon reconstruction technique.
摘要翻译：本发明涉及一种利用水分和脂肪信号分离进行冠状动脉磁共振血管造影的方法，该方法包括：使用多回波狄克逊采集获得冠状动脉磁共振血管造影数据集，处理（314,316,318）重建数据集第一和第二（322）图像数据集，第一和第二图像数据集包括分离的水和脂肪图像数据，其中数据集的处理包括狄克逊重建技术。

8. 发明申请

WO2013093674A1 MR IMAGING WITH SUPPRESSION OF FLOW ARTEFACTS 审中-公开
标题翻译：成像与阻止流动的ARTEFACTS
公开(公告)号：WO2013093674A1
公开(公告)日：2013-06-27
申请号：PCT/IB2012/056748
申请日：2012-11-26
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH
发明人： EGGERS, Holger , BÖRNERT, Peter
IPC分类号： G01R33/565
CPC分类号： G01R33/56563 , G01R33/385 , G01R33/4828 , G01R33/5616 , G01R33/56509 , G01R33/56527
摘要： The invention relates to a method of MR imaging of a body (10) placed in the examination volume of a MR device (1). It is an object of the invention to provide a method that enables efficient compensation of flow artefacts, especially for contrast-enhanced MR angiography in combination with Dixon water/fat separation. The method of the invention comprises the steps of: a) generating at least two gradient echo signals at two different echo times by subjecting the portion of the body (10) to an imaging sequence of RF pulses and switched magnetic field gradients, wherein the 0th moment of the readout magnetic field gradient essentially vanishes at the time of the first gradient echo, the 1st moment of the readout gradient being non-zero at the time of the first gradient echo, while both the 0th and 1st moments of the readout magnetic field gradient essentially vanish at the time of the second gradient echo; b) acquiring the gradient echo signals; c) repeating steps a) and b) for a plurality of phase encoding steps. Moreover, the invention relates to a MR device for carrying out the method of the invention and to a computer program to be run on a MR device; d) reconstructing a first MR image from the gradient echo signals of the first gradient echo and a second MR image from the gradient echo signals of the second gradient echo; and e) identifying ghosting artefacts in the first and/or second MR image by comparing the first and second MR images.
摘要翻译：本发明涉及放置在MR装置（1）的检查体积中的身体（10）的MR成像方法。本发明的一个目的是提供一种能够有效地补偿流动人造物的方法，特别是与Dixon水/脂肪分离相结合的对比度增强MR血管造影术。本发明的方法包括以下步骤：a）通过对身体（10）的部分进行RF脉冲和切换磁场梯度的成像序列，在两个不同回波时间产生至少两个梯度回波信号，其中第0 读出磁场梯度的时刻在第一梯度回波时基本上消失，读出梯度的第一时刻在第一梯度回波时为非零，而读出磁场的第0和第1时刻在第二梯度回波时梯度基本消失; b）获取梯度回波信号; c）对多个相位编码步骤重复步骤a）和b）。此外，本发明涉及一种用于执行本发明的方法的MR设备和一种在MR设备上运行的计算机程序; d）根据第二梯度回波的梯度回波信号，从第一梯度回波的梯度回波信号和第二MR图像重构第一MR图像; 以及e）通过比较第一和第二MR图像来识别第一和/或第二MR图像中的重影伪像。

9. 发明申请

WO2012127341A1 COMPRESSED SENSING MR IMAGE RECONSTRUCTION USING CONSTRAINT FROM PRIOR ACQUISITION 审中-公开
标题翻译：使用来自先前收购的约束的压缩感测MR图像重建
公开(公告)号：WO2012127341A1
公开(公告)日：2012-09-27
申请号：PCT/IB2012/050930
申请日：2012-02-28
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , DONEVA, Mariya Ivanova , REMMELE, Stefanie , BÖRNERT, Peter , MAZURKEWITZ, Peter , SENEGAS, Julien , KEUPP, Jochen , NEHRKE, Kay
发明人： DONEVA, Mariya Ivanova , REMMELE, Stefanie , BÖRNERT, Peter , MAZURKEWITZ, Peter , SENEGAS, Julien , KEUPP, Jochen , NEHRKE, Kay
IPC分类号： G01R33/56 , G01R33/561 , G01R33/567 , G01R33/48
CPC分类号： G01R33/56 , G01R33/4824 , G01R33/5608 , G01R33/5611 , G01R33/56509
摘要： The invention relates to a method of MR imaging of at least a portion of a body (10) of a patient placed in an examination volume of a MR device (1), the method comprising the steps of: - subjecting the portion of the body(10) to a first imaging sequence for acquiring a first signal data set (21); - subjecting the portion of the body (10) to a second imaging sequence for acquiring a second signal data set (23), wherein the imaging parameters of the second imaging sequence differ from the imaging parameters of the first imaging sequence; - reconstructing a MR image from the second signal data set (23) by means of regularization using the first signal data set (21) as prior information. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).
摘要翻译：本发明涉及放置在MR装置（1）的检查体积中的患者的身体（10）的至少一部分的MR成像方法，该方法包括以下步骤： - 对身体的部分（10）到用于获取第一信号数据集（21）的第一成像序列; - 将所述身体（10）的所述部分经受第二成像序列以获取第二信号数据集（23），其中所述第二成像序列的成像参数与所述第一成像序列的成像参数不同; - 通过使用第一信号数据集（21）的正则化作为先验信息，从第二信号数据集（23）重建MR图像。此外，本发明涉及MR设备（1）和用于MR设备（1）的计算机程序。

10. 发明申请

WO2004081518A3 MR IMAGING METHOD 审中-公开
公开(公告)号：WO2004081518A3
公开(公告)日：2004-09-23
申请号：PCT/IB2004/050164
申请日：2004-02-27
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , LEUSSLER, Christoph, Günther , BÖRNERT, Peter
发明人： LEUSSLER, Christoph, Günther , BÖRNERT, Peter
IPC分类号： G01R33/561
摘要： The invention relates to an MR method for generating an image of a body part of a patient located in the examination volume of an MR device. According to the method, firstly MR signals are excited in the examination volume by means of a sequence of magnetic field gradient pulses (15, 16, 17) and/or RF pulses (14). Thereafter, the MR signals are recorded by means of an RF coil arrangement of the MR device, where the RF coil arrangement has a number of coil elements that can be actuated individually. Finally, image reconstruction from the recorded MR signals takes place. For the purpose of imaging that is as rapid as possible while at the same time physiologically exposing the patient to magnetic field gradient pulses or RF pulses to a minimum extent, the invention proposes that the spatial RF field distribution during excitation of the MR signals and/or the spatial sensitivity profile of the RF coil arrangement during recording of the MR signals be varied by suitable actuation (C1, C2) of the RF coil arrangement.

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