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1. 发明申请

WO2012143824A1 INTERLEAVED BLACK AND BRIGHT BLOOD DYNAMIC CONTRAST ENHANCED (DCE) MRI 审中-公开
标题翻译：交互式BLACK和BRIGHT BLOOD动态对比增强（DCE）MRI
公开(公告)号：WO2012143824A1
公开(公告)日：2012-10-26
申请号：PCT/IB2012/051779
申请日：2012-04-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , UNIVERSITY OF WASHINGTON , WANG, Jinnan , CHEN, Huijun , BÖRNERT, Peter , YUAN, Chun
发明人： WANG, Jinnan , CHEN, Huijun , BÖRNERT, Peter , YUAN, Chun
IPC分类号： G01R33/563
CPC分类号： G01R33/48 , G01R33/56316 , G01R33/5635
摘要： Interleaved black/bright imaging (IBBI) is performed using a magnetic resonance (MR) scanner (10) wherein the black blood module (52) of the IBBI includes: applying a first flow sensitization gradient; applying a spoiler gradient after applying the first flow sensitization gradient; applying a second flow sensitization gradient after applying the spoiler gradient wherein the second flow sensitization gradient has area equal to the first flow sensitation gradient but of opposite polarity; applying a slice selective radio frequency excitation pulse after applying the spoiler gradient; and performing a MR readout after applying the second flow sensitization gradient and after applying the slice selective radio frequency excitation wherein the readout acquires MR imaging data having blood signal suppression in the region excited by the slice selective radio frequency excitation pulse. The MR imaging data having blood signal suppression is reconstructed to generate black blood images (20), and MR imaging data generated by bright blood modules (50) of the IBBI is reconstructed to generate bright blood images (22).
摘要翻译：使用磁共振（MR）扫描器（10）进行交错黑/亮成像（IBBI），其中IBBI的黑血模块（52）包括：施加第一流感敏化梯度; 在应用第一流感敏化梯度后应用扰流板梯度; 在施加扰流板梯度之后施加第二流动增感梯度，其中第二流动增感梯度具有等于第一流动感觉梯度但具有相反极性的面积; 应用扰流板梯度后应用切片选择性射频激励脉冲; 以及在应用所述第二流敏增强梯度之后并且在施加所述切片选择性射频激发之后执行MR读出，其中所述读出器获取在由所述切片选择性射频激励脉冲激发的区域中具有血液信号抑制的MR成像数据。重建具有血液信号抑制的MR成像数据以产生黑血图像（20），并重建由IBBI的亮血模块（50）产生的MR成像数据，以产生亮血图像（22）。

2. 发明授权

EP2699929B1 INTERLEAVED BLACK AND BRIGHT BLOOD MRI 有权转让
公开(公告)号：EP2699929B1
公开(公告)日：2019-12-11
申请号：EP12722857.5
申请日：2012-04-12
申请人： Koninklijke Philips N.V. , Philips Intellectual Property & Standards GmbH , The University of Washington
发明人： WANG, Jinnan , CHEN, Huijun , BÖRNERT, Peter , YUAN, Chun
IPC分类号： G01R33/563

3. 发明公开

EP2699929A1 INTERLEAVED BLACK AND BRIGHT BLOOD DYNAMIC CONTRAST ENHANCED (DCE) MRI 有权转让
标题翻译：动态增强MRI隔行黑亮BLOOD
公开(公告)号：EP2699929A1
公开(公告)日：2014-02-26
申请号：EP12722857.5
申请日：2012-04-12
申请人： Koninklijke Philips N.V. , Philips Intellectual Property & Standards GmbH , The University of Washington
发明人： WANG, Jinnan , CHEN, Huijun , BÖRNERT, Peter , YUAN, Chun
IPC分类号： G01R33/563
摘要： Interleaved black/bright imaging (IBBI) is performed using a magnetic resonance (MR) scanner wherein the black blood module of the IBBI includes: applying a first flow sensitization gradient; applying a spoiler gradient after applying the first flow sensitization gradient; applying a second flow sensitization gradient after applying the spoiler gradient wherein the second flow sensitization gradient has area equal to the first flow sensitization gradient but of opposite polarity; applying a slice selective radio frequency excitation pulse after applying the spoiler gradient; and performing a MR readout after applying the second flow sensitization gradient and after applying the slice selective radio frequency excitation wherein the readout acquires MR imaging data having blood signal suppression in the region excited by the slice selective radio frequency excitation pulse. The MR imaging data having blood signal suppression is reconstructed to generate black blood images, and MR imaging data generated by bright blood modules of the IBBI is reconstructed to generate bright blood images.

4. 发明申请

WO2015092593A1 OPTICAL BASED SUBJECT MOTION DETECTION IN IMAGING SYSTEMS 审中-公开
标题翻译：成像系统中基于光学的主体运动检测
公开(公告)号：WO2015092593A1
公开(公告)日：2015-06-25
申请号：PCT/IB2014/066569
申请日：2014-12-04
申请人： KONINKLIJKE PHILIPS N.V. , TSINGHUA UNIVERSITY , UNIVERSITY OF WASHINGTON
发明人： CHEN, Huijun , WANG, Jinnan , YUAN, Chun
IPC分类号： A61B6/03 , A61B6/00
CPC分类号： A61B6/527 , A61B5/055 , A61B6/027 , A61B6/032 , A61B6/037 , A61B6/0407 , A61B6/0492 , A61B6/4035 , A61B6/5288 , A61B6/54 , A61B6/541
摘要： An imaging system (100) includes a subject support (114) that supports a subject in an examination region (106). The imaging system further includes a detector (112) that detects a signal traversing the examination region, generating an output indicative of the examination region. The imaging system further includes a subject motion sensing system (118) that includes an optical system (206, 208, 214) that detects motion of the subject in the examination region and generates motion data indicative thereof. The imaging system further includes a console (122) that controls at least one of data acquisition or reconstruction based on the motion data.
摘要翻译：成像系统（100）包括支撑检查区域（106）中的对象的对象支撑（114）。成像系统还包括检测器（112），其检测穿过检查区域的信号，产生指示检查区域的输出。成像系统还包括主体运动感测系统（118），其包括检测被检体在检查区域中的运动并产生指示其的运动数据的光学系统（206,208,214）。成像系统还包括控制台（122），其基于运动数据来控制数据获取或重建中的至少一个。

5. 发明申请

WO2014091433A1 INTERLEAVED BLACK AND BRIGHT BLOOD IMAGING FOR INTERLEAVED DYNAMIC CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：用于交互式动态对比增强的磁共振成像的交互式黑色和明亮的血液成像
公开(公告)号：WO2014091433A1
公开(公告)日：2014-06-19
申请号：PCT/IB2013/060831
申请日：2013-12-12
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH , UNIVERSITY OF WASHINGTON
发明人： WANG, Jinnan , CHEN, Huijun , BOERNERT, Peter , YUAN, Chun
IPC分类号： G01R33/56 , G01R33/563
CPC分类号： G01R33/5635 , A61B5/0263 , G01R33/5601 , G01R33/5607 , G01R33/56366
摘要： A magnetic resonance system (10),and corresponding method, image a subject using a conversion-free interleaved black and bright blood imaging (cfIBBI) sequence. A MR scanner (12) is controlled to perform a plurality of repetitions of a black blood imaging sequence (52). The black blood imaging sequence (52) includes a tissue nulling sub-sequence followed by a black blood acquisition sub-sequence (56) performed a time interval (TI) after the tissue nulling sub-sequence. The MR scanner (12) is further controlled to, between successive repetitions of the black blood imaging sequence (52), perform a bright blood imaging sequence (54) including the tissue nulling sub-sequence followed by a bright blood acquisition sub-sequence (58) performed the time interval (TI) after the tissue nulling sub-sequence. The time intervals (TI) of the black blood imaging sequence (52) and the bright blood imaging sequence (54) are of the same duration.
摘要翻译：磁共振系统（10）和相应的方法，使用无转换交错黑和亮血液成像（cfIBBI）序列对对象进行成像。控制MR扫描器（12）以执行黑血成像序列（52）的多次重复。黑血成像序列（52）包括在组织置零子序列之后执行时间间隔（TI）的随后是黑血采集子序列（56）的组织零位子序列。 MR扫描器（12）进一步被控制在连续重复黑血成像序列（52）之间，执行明亮的血液成像序列（54），该血液成像序列（54）包括组织清空子序列，接着是明亮的血液获取子序列 58）在组织归零子序列之后执行时间间隔（TI）。黑血成像序列（52）和亮血成像序列（54）的时间间隔（TI）具有相同的持续时间。

6. 发明公开

EP2932290A1 INTERLEAVED BLACK AND BRIGHT BLOOD IMAGING FOR INTERLEAVED DYNAMIC CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：黑色和亮血嵌套的动态对比度嵌套成像增强磁成像
公开(公告)号：EP2932290A1
公开(公告)日：2015-10-21
申请号：EP13830096.7
申请日：2013-12-12
申请人： Koninklijke Philips N.V. , Philips GmbH , University of Washington
发明人： WANG, Jinnan , CHEN, Huijun , BOERNERT, Peter , YUAN, Chun
IPC分类号： G01R33/56 , G01R33/563
CPC分类号： G01R33/5635 , A61B5/0263 , G01R33/5601 , G01R33/5607 , G01R33/56366
摘要： A magnetic resonance system (10),and corresponding method, image a subject using a conversion-free interleaved black and bright blood imaging (cfIBBI) sequence. A MR scanner (12) is controlled to perform a plurality of repetitions of a black blood imaging sequence (52). The black blood imaging sequence (52) includes a tissue nulling sub-sequence followed by a black blood acquisition sub-sequence (56) performed a time interval (TI) after the tissue nulling sub-sequence. The MR scanner (12) is further controlled to, between successive repetitions of the black blood imaging sequence (52), perform a bright blood imaging sequence (54) including the tissue nulling sub-sequence followed by a bright blood acquisition sub-sequence (58) performed the time interval (TI) after the tissue nulling sub-sequence. The time intervals (TI) of the black blood imaging sequence (52) and the bright blood imaging sequence (54) are of the same duration.
摘要翻译：一种磁共振系统（10），和相应的方法，图像使用无转化交织黑色和亮血成像（cfIBBI）序列的受试者。 MR扫描器（12）被控制以执行一个黑血成像序列（52）的重复的多元性。黑血成像序列（52）包括组织零陷随之而来的是黑色血液获取子序列（56）的子序列所执行的调零组织子序列之后的时间间隔（TI）。 MR扫描器（12）被进一步控制，黑血成像序列（52）执行包括所述组织归零随之而来的是明亮的血液获取子序列的子序列的亮血成像序列（54）的连续重复（间 58）组织归零子序列之后所执行的时间间隔（TI）。黑血成像序列（52）和亮血成像序列（54）的时间间隔（TI）是相同的持续时间。

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