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1. 发明公开

EP2747656A1 WHOLE-BODY SPECT SYSTEM 有权转让
标题翻译： SYSTEM FOR分析全身
公开(公告)号：EP2747656A1
公开(公告)日：2014-07-02
申请号：EP12816120.5
申请日：2012-11-15
申请人： Koninklijke Philips N.V. , Philips Deutschland GmbH
发明人： WIECZOREK, Herfried Karl , YE, Jinghan , SHAO, Lingxiong
IPC分类号： A61B6/00 , A61B6/03 , G01T1/164 , G01T1/29
CPC分类号： A61B6/4266 , A61B6/037 , A61B6/0407 , A61B6/0457 , A61B6/4258 , A61B6/4275 , A61B6/4291 , A61B6/5205 , G01T1/1644 , G01T1/249
摘要： A whole body SPECT system (10) includes a patient support (14) and a static gantry (12) which includes a plurality of rings (40a,40b,40c) of radiation detectors (42). The patient support (14) supports a patient and moves the patient in an axial direction (18) through the static gantry (12). One or more processors (20,24,32) connected to the plurality of detectors records strikes of gamma photons in the radiation detectors (42) and reconstruct the recorded strikes of the gamma photons into a whole body image.

2. 发明授权

EP2783240B1 GANTRY-FREE SPECT SYSTEM 有权转让
公开(公告)号：EP2783240B1
公开(公告)日：2018-08-22
申请号：EP12812360.1
申请日：2012-11-12
申请人： Koninklijke Philips N.V. , Philips Deutschland GmbH
发明人： WIECZOREK, Herfried, Karl , YE, Jinghan , SHAO, Lingxiong , HASSAN, Rizwan
IPC分类号： G01T1/164 , A61B6/03
CPC分类号： G01T1/2985 , A61B6/037 , A61B6/4258 , A61B6/469 , A61B6/506 , G01T1/1648
摘要： A gantry free nuclear imaging system (10) images a region of interest (ROI) (16). The system (10) includes one or more radiation detectors (20) generating radiation data indicating the location of gamma photon strikes. The system includes a reconfigurable frame (22) positioning the radiation detectors (20) at fixed viewing angles of the ROI (16) and at least one processor (44, 48). The processor (44, 48) receives the radiation data from the radiation detectors (20) and reconstructs an image of the ROI (16) from the received radiation data.

3. 发明公开

EP2783240A1 GANTRY-FREE SPECT SYSTEM 有权转让
标题翻译：龙门展示系统
公开(公告)号：EP2783240A1
公开(公告)日：2014-10-01
申请号：EP12812360.1
申请日：2012-11-12
申请人： Koninklijke Philips N.V. , Philips Deutschland GmbH
发明人： WIECZOREK, Herfried, Karl , YE, Jinghan , SHAO, Lingxiong , HASSAN, Rizwan
IPC分类号： G01T1/164 , A61B6/03
CPC分类号： G01T1/2985 , A61B6/037 , A61B6/4258 , A61B6/469 , A61B6/506 , G01T1/1648
摘要： A gantry free nuclear imaging system (10) images a region of interest (ROI) (16). The system (10) includes one or more radiation detectors (20) generating radiation data indicating the location of gamma photon strikes. The system includes a reconfigurable frame (22) positioning the radiation detectors (20) at fixed viewing angles of the ROI (16) and at least one processor (44, 48). The processor (44, 48) receives the radiation data from the radiation detectors (20) and reconstructs an image of the ROI (16) from the received radiation data.

4. 发明申请

WO2016059557A1 PET DETECTOR SCINTILLATOR ARRANGEMENT WITH LIGHT SHARING AND DEPTH OF INTERACTION ESTIMATION 审中-公开
标题翻译： PET检测器扫描仪安装与光共享和深度相互作用估计
公开(公告)号：WO2016059557A1
公开(公告)日：2016-04-21
申请号：PCT/IB2015/057843
申请日：2015-10-14
申请人： KONINKLIJKE PHILIPS N.V. , UNIVERSITY OF WASHINGTON
发明人： SOWARDS-EMMERD, David , LEHNERT, Adrienne , HUNTER, William , MIYAOKA, Robert , SHAO, Lingxiong , LAURENCE, Thomas Leroy
IPC分类号： G01T1/164
CPC分类号： G01T1/1644 , G01T1/2018 , G01T1/202
摘要： A photon detector includes a sensor array of optical sensors disposed in a plane and four substantially identical scintillation crystal bars. Each optical sensor is configured to sense luminescence. Each of the four scintillator crystal bars being a rectangular prism with four side surfaces and first and second end surfaces, each scintillation bar has two side surfaces which each face a side surface of another scintillation bar, and each scintillation crystal bar generating a light scintillation in response to interacting with a received gamma photon. A first layer (80) is disposed in a first plane disposed between and adjacent facing side surfaces of the four substantially identical scintillation crystal bars with a light sharing portion (82) adjacent the first end surface and a reflective portion (84) adjacent the second end surface. A second layer (68) is disposed in a second plane orthogonal to the first plane and disposed between and adjacent facing side surfaces of the four substantially identical scintillation crystal bars with a light sharing portion (88) adjacent the second end surface and a reflective portion (90) adjacent the first end surface.
摘要翻译：光子检测器包括设置在平面中的光学传感器的传感器阵列和四个基本相同的闪烁晶体棒。每个光学传感器被配置为感测发光。四个闪烁体晶体棒中的每一个是具有四个侧表面和第一和第二端表面的矩形棱镜，每个闪烁棒具有两个侧表面，每个表面面对另一个闪烁棒的侧表面，并且每个闪烁晶体棒产生闪烁与接收的伽马光子相互作用的响应。第一层（80）设置在设置在四个基本上相同的闪烁晶体棒的相邻的相对侧表面之间的相邻面的第一平面中，具有与第一端面相邻的光共享部分（82）和邻近第二端端面。第二层（68）设置在与第一平面正交的第二平面中，并且设置在四个基本上相同的闪烁晶体棒的相邻的相对的侧表面之间，并且邻近第二端面的光共享部分（88）和反射部分（90）邻近第一端面。

5. 发明申请

WO2016092394A1 SYSTEMS AND METHODS FOR TRANSLATION OF MEDICAL IMAGING USING MACHINE LEARNING 审中-公开
标题翻译：使用机器学习翻译医学成像的系统和方法
公开(公告)号：WO2016092394A1
公开(公告)日：2016-06-16
申请号：PCT/IB2015/058995
申请日：2015-11-20
申请人： KONINKLIJKE PHILIPS N.V. , CASE WESTERN RESERVE UNIVERSITY , UNIVERSITY HOSPITALS MEDICAL GROUP, INC.
发明人： HU, Lingzhi , SHAO, Lingxiong , MUZIC, Raymond Frank , SU, Kuan-Hao , QIAN, Pengjiang
IPC分类号： G06T11/00
CPC分类号： G06T11/006 , G06T5/007 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/20081 , G06T2207/20221
摘要： A medical image(24) with contrast of one imaging modality is emulated from images with other contrast characteristics. A plurality of input images (20) of a region of interest with the other contrast characteristics is received. A transform (22) which was generated by machine learning is applied to the corresponding plurality of input images (20) to generate a scalar value (38) or a vector value (38') representing the corresponding voxel (36ʹ) of the medical image (24) to be evaluated.
摘要翻译：具有一种成像模式的对比度的医学图像（24）从具有其他对比度特征的图像中模拟。接收具有其他对比度特性的感兴趣区域的多个输入图像（20）。将通过机器学习产生的变换（22）应用于对应的多个输入图像（20），以生成表示医学图像的相应体素（36'）的标量值（38）或矢量值（38'）（24）进行评估。

6. 发明申请

WO2015011584A3 DIFFERENTIATING TISSUES WITH MRI USING MULTI-ECHO ULTRA-SHORT TE (UTE) WITH MDIXON PULSE SEQUENCE 审中-公开
公开(公告)号：WO2015011584A3
公开(公告)日：2015-01-29
申请号：PCT/IB2014/062787
申请日：2014-07-02
申请人： KONINKLIJKE PHILIPS N.V.
发明人： HU, Lingzhi , STEHNING, Christian , HU, Zhiqiang , SHAO, Lingxiong
IPC分类号： G01R33/48 , G01R33/56
摘要： A medical imaging system (10) includes a magnetic resonance (MR) scanner (12), and a MR reconstruction unit (34). The MR scanner (12) applies a multi-echo ultra-short TE (UTE) with mDixon pulse sequence to a subject (16) and receives MR data (33) representing at least a portion of the subject. The MR reconstruction unit (34) reconstructs a Free Induction Decay (FID) image (120), and one or more echo magnitude images (122), one or more phase images (39), an in-phase image (39), a water image (39), and a fat image (39) from the received MR data (33).

7. 发明申请

WO2015092622A2 DENSITY GUIDED ATTENUATION MAP GENERATION IN PET/MR SYSTEMS 审中-公开
标题翻译： PET / MR系统中的密度指导衰减图生成
公开(公告)号：WO2015092622A2
公开(公告)日：2015-06-25
申请号：PCT/IB2014/066765
申请日：2014-12-10
申请人： KONINKLIJKE PHILIPS N.V.
发明人： BERKER, Yannick , DWIVEDI, Shekhar , SCHULZ, Volkmar , SHAO, Lingxiong
IPC分类号： G01R33/48
CPC分类号： G01R33/56509 , A61B5/0035 , A61B5/055 , G01R33/481 , G01R33/4816 , G01R33/4835 , G01R33/50 , G01R33/5608 , G01T1/1603 , G01T1/1647 , G06T7/11 , G06T7/136 , G06T2207/10088 , G06T2207/20132 , G06T2207/30061
摘要： A lung segmentation processor (40) is configured to classify magnetic resonance (MR) images based on noise characteristics. The MR segmenatation processor generates a lung region of interest (ROI) and detailed structure segmentation of the lung from the ROI. The MR segmentation processor performs an iterative normalization and region definition approach that captures the entire lung and the soft tissues within the lung accurately. Accuracy of the segmentation relies on artifact classification coming inherently from MR images. The MR segmentation processor (40) correlates segmented lung internal tissue pixels with the lung density to determine the attenuation coefficients based on the correlation. Lung densities are computed using MR data obtained from imaging sequences that minimize echo and acquisition times. The densities differentiate healthy tissues and lesions, which an attenuation map processor (36) uses to create localized attenuation maps for the lung.
摘要翻译：肺分割处理器（40）被配置为基于噪声特性对磁共振（MR）图像进行分类。 MR分割处理器生成感兴趣的肺部区域（ROI）和来自ROI的肺的详细结构分割。 MR分段处理器执行迭代归一化和区域定义方法，准确地捕获肺内整个肺和软组织。分割的准确性依赖于来自MR图像的固有的伪影分类。 MR分割处理器（40）将分割的肺内部组织像素与肺密度相关联，以基于相关性来确定衰减系数。使用从使回波和采集时间最小化的成像序列获得的MR数据计算肺密度。密度区分健康组织和病变，衰减图处理器（36）用于为肺创建局部衰减图。

8. 发明申请

WO2013144781A2 PORTABLE MEDICAL IMAGER WITH GUI INTERFACE 审中-公开
标题翻译：便携式医疗影像与GUI界面
公开(公告)号：WO2013144781A2
公开(公告)日：2013-10-03
申请号：PCT/IB2013/052199
申请日：2013-03-20
申请人： KONINKLIJKE PHILIPS N.V.
发明人： HASSAN, Rizwan , SHAO, Lingxiong , ALLEN, Steven
IPC分类号： G01T1/164
CPC分类号： A61B6/527 , A61B6/037 , A61B6/4028 , A61B6/4216 , A61B6/4258 , A61B6/4283 , A61B6/4405 , A61B6/462 , A61B6/466 , A61B6/469 , A61B6/506 , A61B6/5205 , A61B6/547 , G01T1/164
摘要： A portable imaging system for imaging a region of interest (ROI)includes a housing (12), a radiation detector(16)mounted to the housing (12), the detetor generating radiation data indicating a location of gamma photon strikes on the detector, a motion sensor (20) which senses motion of the detector and outputs motion data indicative of the location and orientation of the deteector at the time of each gamma photon strike, and at least one processor (22, 26) programmed to receive the radiation data from the radiation detectors (16) and the motion data from the motion sensor (20)and reconstruct a 3D volume image of the ROI from the received radiation and motion data.
摘要翻译：用于对感兴趣区域（ROI）进行成像的便携式成像系统包括壳体（12），安装到壳体（12）的辐射探测器（16），所述探测器产生指示伽马光子撞击检测器的位置的辐射数据，感测所述检测器运动的运动传感器（20），并输出指示每个伽马射线光子发射时所述检测器的位置和取向的运动数据，以及被编程为接收所述辐射数据的至少一个处理器（22,26）来自辐射检测器（16）和来自运动传感器（20）的运动数据，并且从接收的辐射和运动数据重建ROI的3D体积图像。

9. 发明申请

WO2013118017A1 CLINICALLY DRIVEN IMAGE FUSION 审中-公开
标题翻译：临床驱动图像融合
公开(公告)号：WO2013118017A1
公开(公告)日：2013-08-15
申请号：PCT/IB2013/050710
申请日：2013-01-28
申请人： KONINKLIJKE PHILIPS N.V.
发明人： PREVRHAL, Sven , HANSIS, Eberhard Sebastian , BREDNO, Joerg , YE, Jinghan , SONG, Xiyun , TUNG, Chi-Hua , SHAO, Lingxiong
IPC分类号： G06T5/50 , G06T7/00
CPC分类号： G06T11/005 , G06T5/50 , G06T7/97 , G06T11/008 , G06T2207/10072 , G06T2207/10081 , G06T2207/10084 , G06T2207/10104 , G06T2207/20008 , G06T2207/20221 , G06T2207/30004 , G06T2211/416
摘要： A medical imaging system includes a data store (16) of reconstruction procedures, a selector (24), a reconstructor (14), a fuser (28), and a display (22). The data store (16) of reconstruction procedures identifies a plurality of reconstruction procedures. The selector (24) selects at least two reconstruction procedures from the data store of reconstruction procedures based on a received input, each reconstruction procedure optimized for one or more image characteristics. The reconstructor (14) concurrently performs the selected at least two reconstruction procedures, each reconstruction procedure generates at least one image (26) from the at least one data store of imaging data (12). The fuser (28) fuses the at least two generated medical images to create a medical diagnostic image which includes characteristics from each generated image (26). The display (22) displays the medical diagnostic image.
摘要翻译：医疗成像系统包括重建程序的数据存储器（16），选择器（24），重建器（14），定影器（28）和显示器（22）。重建程序的数据存储器（16）识别多个重建程序。选择器（24）基于接收的输入从重建程序的数据存储区中选择至少两个重建过程，每个重建程序针对一个或多个图像特征优化。重构器（14）同时执行所选择的至少两个重建过程，每个重建过程从成像数据（12）的至少一个数据存储区生成至少一个图像（26）。定影器（28）使至少两个生成的医学图像融合以创建包括来自每个生成的图像（26）的特征的医学诊断图像。显示器（22）显示医疗诊断图像。

10. 发明申请

WO2016067145A1 AUTOMATED QUANTITATIVE IMAGING SYSTEM 审中-公开
标题翻译：自动定量成像系统
公开(公告)号：WO2016067145A1
公开(公告)日：2016-05-06
申请号：PCT/IB2015/057905
申请日：2015-10-15
申请人： KONINKLIJKE PHILIPS N.V.
发明人： CONNER, Joseph , NORTMANN, Charles , SHAO, Lingxiong
IPC分类号： A61B6/00 , A61B6/03 , A61M5/00 , A61K51/00 , C07B59/00
CPC分类号： A61B6/545 , A61B6/00 , A61B6/03 , A61B6/037 , A61B6/486 , A61B6/5205 , A61B6/582 , A61M5/007 , A61M5/172 , A61M5/5086 , G06T11/003
摘要： A quantitative imaging system (100) for automating delivery of a radiopharmaceutical and imaging a patient. The system (100) includes a QI controller (102) that controls the operation of the system. The system (100) includes a producer (104) for creating a radiopharmaceutical and a synthesizer (106) to synthesize the radioisotope with a biologically compatible material to form the radiopharmaceutical. The system (100) includes a dosimeter (110) to measure and timestamp the concentration measurement of the radiopharmaceutical and an injector (112) to deliver the radiopharmaceutical into the patient. The system (100) includes an imaging apparatus (114) to image the patient. The QI controller (102) uses the timestamp of the concentration and decay characteristics to adjust imaging data. The system includes aquantitative analyzer (116) to calculate parametric images and quantitative values from the collected data.
摘要翻译：一种定量成像系统（100），用于自动化递送放射性药物并使患者成像。系统（100）包括控制系统的操作的QI控制器（102）。系统（100）包括用于产生放射性药物的生成器（104）和用于将放射性同位素与生物相容性材料合成以形成放射性药物的合成器（106）。系统（100）包括用于测量和时间戳放射性药物的浓度测量的剂量计（110）和用于将放射性药物递送到患者体内的注射器（112）。该系统（100）包括成像设备（114），用于对患者进行成像。 QI控制器（102）使用浓度和衰减特性的时间戳来调整成像数据。该系统包括水分分析仪（116），用于从收集的数据中计算参数图像和定量值。

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