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1. 发明授权

US4668820A Method of preparing polyprenyl compounds or mixtures thereof 失效
标题翻译：聚异戊二烯基化合物或其混合物的制备方法
公开(公告)号：US4668820A
公开(公告)日：1987-05-26
申请号：US722173
申请日：1985-04-10
申请人： Koichi Ibata , Tetsuo Takigawa , Masafumi Okada , Masao Mizuno , Takashi Nishida
发明人： Koichi Ibata , Tetsuo Takigawa , Masafumi Okada , Masao Mizuno , Takashi Nishida
IPC分类号： C07C69/007 , C07C27/00 , C07C29/74 , C07C29/76 , C07C29/88 , C07C33/02 , C07C67/00 , C07C67/54 , C07C69/025 , C08F8/12 , C08F8/14 , C07C67/48 , C07C67/52
CPC分类号： C07C33/02 , C07C29/76
摘要： Polyprenols or esters thereof, which are similar in the trans and cis configurations to dolichol, or mixtures thereof are obtained from the leaves of plants belonging to the genus Pinus L. of the family Pinaceae by extraction, if necessary followed by hydrolysis, esterification or transesterification or a combination thereof. These polyprenyl compounds and mixtures thereof are useful as favorable starting materials for the synthesis of dolichol.
摘要翻译：通过提取，如果需要，然后进行水解，酯化或酯交换，从属于松果科属松属植物的植物的叶子获得反式和顺式构型与二醇的类似的聚螺旋体或其酯或其混合物或其组合。这些聚异戊二烯基化合物及其混合物可用作合成双氯酚的有利原料。

2. 发明授权

US4564477A Polyprenyl compounds and method of producing the same 失效
标题翻译：聚丙烯基化合物及其制备方法
公开(公告)号：US4564477A
公开(公告)日：1986-01-14
申请号：US467253
申请日：1983-02-17
申请人： Tetsuo Takigawa , Koichi Ibata , Masafumi Okada , Masao Mizuno , Takashi Nishida
发明人： Tetsuo Takigawa , Koichi Ibata , Masafumi Okada , Masao Mizuno , Takashi Nishida
IPC分类号： C07C29/14 , C07C29/147 , C07C45/29 , C07C45/30 , C07C45/59 , C07C45/67 , C07C47/21 , C07C49/203 , C07C57/03 , C07C69/587 , C07D295/02 , C07D295/03 , C07D295/185 , C09F5/00
CPC分类号： C07D295/185 , C07C255/00 , C07C29/14 , C07C29/147 , C07C45/292 , C07C45/298 , C07C45/305 , C07C45/59 , C07C45/676 , C07C47/21 , C07C49/203 , C07C57/03 , C07D295/03
摘要： There are provided polyprenyl compounds of the formula ##STR1## wherein ##STR2## represent a trans-isoprene unit and a cis-isoprene unit, respectively, n is an integer of 11-19, Z.sup.1 and Z.sup.2 combinedly represent .dbd.O, .dbd.CH--COOH,.dbd.CH--COOR.sup.1, .dbd.CH--CN, .dbd.C(CN)COOR.sup.2, .dbd.CH--CO--NH.sub.2, .dbd.CH--CO--N(R.sup.3) (R.sup.4), .dbd.CH--CO--NHR.sup.5, .dbd.CH--CH.sub.2 --N(R.sup.3) (R.sup.4), .dbd.CH--CH.sub.2 --NHR.sup.5 or .dbd.CH--CHO or Z.sup.1 is a hydrogen atom and Z.sup.2 is --CH.sub.2 COOH, --CH.sub.2 COOR.sup.6, --CH(CN)COOR.sup.2, --CH.sub.2 CN, --CH.sub.2 --CO--NH.sub.2, --CH.dbd.CH--N(R.sup.3) (R.sup.4) or --CH.sub.2 --CH.dbd.N--R.sup.5, R.sup.1, R.sup.2 and R.sup.6 each being a lower alkyl group, R.sup.3 and R.sup.4 each independently being a lower-alkyl, cycloalkyl, aryl or aralkyl group or R.sup.3 and R.sup.4 combinedly representing an alkylene group containing 2-5 carbon atoms, and R.sup.5 being a lower-alkyl, cycloalkyl, aryl or aralkyl group. These polyprenyl compounds can be synthesized starting with a polyprenol obtainable from leaves of a plant such as Ginkgo biloba or Cedrus deodara by extraction and as necessary followed by hydrolysis, or a reactive derivative thereof. The polyprenyl compounds are useful as intermediates for the synthesis of dolichol without the use of an expensive C.sub.5 chain extender.
摘要翻译：提供下式的聚异戊二烯基化合物：其中，“IMAGE”分别代表异戊二烯单元和顺式异戊二烯单元，n为11-19的整数，Z1和Z2组合表示 = CH 2 COOR 1 = CH-COOR 1 = CH-CN = C（CN）COOR 2 = CH-CO-NH 2 = CH-CO-N（R3）（R4） NHR 5，= CH-CH 2 -N（R 3）（R 4），= CH-CH 2 -NHR 5或= CH-CHO或Z 1是氢原子，Z 2是-CH 2 COOH，-CH 2 COOR 6，-CH（CN）COOR 2，-CH 2 CN ，-CH 2 -CO-NH 2，-CH = CH-N（R 3）（R 4）或-CH 2 -CH = N-R 5，R 1，R 2和R 6各自为低级烷基，R 3和R 4各自独立地为低级 - 烷基，环烷基，芳基或芳烷基或R3和R4组合表示含2-5个碳原子的亚烷基，R5为低级烷基，环烷基，芳基或芳烷基。这些聚异戊二烯基化合物可以从通过提取从植物如银杏叶或Cedrus deodara的叶获得的聚异戊二烯开始合成，并且根据需要随后进行水解或其活性衍生物合成。聚异戊二烯基化合物可用作合成Dolichol而不使用昂贵的C5扩链剂的中间体。

3. 发明授权

US4792615A Method of producing .alpha.-dihydropolyprenyl monophosphates 失效
标题翻译： α-二氢聚丙烯基单磷酸盐的制备方法
公开(公告)号：US4792615A
公开(公告)日：1988-12-20
申请号：US429
申请日：1986-12-22
申请人： Naoshi Nakagawa , Tetsuo Takigawa , Akira Kageyu , Michiya Shimamura , Masafumi Okada , Masao Mizuno
发明人： Naoshi Nakagawa , Tetsuo Takigawa , Akira Kageyu , Michiya Shimamura , Masafumi Okada , Masao Mizuno
IPC分类号： C07F9/113 , C07H11/04 , C07F9/09
CPC分类号： C07H11/04 , C07F9/113
摘要： A method of producing .alpha.-dihydropolyprenyl monophosphates from .alpha.-dihydropolyprenols through .alpha.-dihydropolyprenyl dichlorophosphates in good yield and with ease is provided. A method of producing .alpha.-dihydropolyprenyl dichlorophosphates which are intermediate compounds useful for the first-mentioned method is also provided.
摘要翻译：提供了从α-二氢聚戊二醇通过α-二氢聚丙烯基二氯磷酸盐以良好的产率和容易地制备α-二氢聚芘基单磷酸酯的方法。还提供了用于第一种方法的中间体化合物的制备α-二氢聚丙烯基二氯磷酸盐的方法。

4. 发明授权

US4948784A Platinum containing pullulan derivatives and compositions containing the same 失效
标题翻译：含铂的支链淀粉衍生物和含有其的组合物
公开(公告)号：US4948784A
公开(公告)日：1990-08-14
申请号：US163961
申请日：1988-01-20
申请人： Fumio Mori , Masafumi Okada , Shuji Miki , Iwao Ebashi , Takashi Nishida , Kouichiro Kawai , Tazuko Tashiro , Shigeru Tsukagoshi
发明人： Fumio Mori , Masafumi Okada , Shuji Miki , Iwao Ebashi , Takashi Nishida , Kouichiro Kawai , Tazuko Tashiro , Shigeru Tsukagoshi
IPC分类号： C08B37/00
CPC分类号： C08B37/0018
摘要： A pullulan derivative having one or more active sites resulting from introduction of sulfuric acid, phosphoric acid, a sulfonic acid or a carboxylic acid, wherein one hydrogen atom of the group of the formula ##STR1## occurring at said active sites is partly substituted by a group of the general formula ##STR2## wherein L.sup.1 and L.sup.2 each independently is ammine or a unidentate ligand amine or combinedly represent a bidentate ligand amine and Y is an anionic ligand, and/or two hydrogen atoms of the group ##STR3## or of two ##STR4## groups bound to one and the same carbon atom or to two neighboring carbon atoms as occurring at said active sites are, each independently, partly substituted by a group of the general formula ##STR5## wherein L.sup.1 and L.sup.2 are as defined above, and a pharmacologically acceptable salt thereof.The above compound has anticancer activity and is useful as anticancer agents.The present invention is concerned with said compound, a process for producing the same and a pharmaceutical use thereof.

5. 发明授权

US5100877A Platinum containing pullulan derivatives and pharmaceutical compositions comprising the same 失效
标题翻译：含铂的支链淀粉衍生物和包含其的药物组合物
公开(公告)号：US5100877A
公开(公告)日：1992-03-31
申请号：US282398
申请日：1988-12-05
申请人： Fumio Mori , Masafumi Okada , Shuji Miki , Iwao Ebashi , Takashi Nishida , Kouichiro Kawai , Tazuko Tashiro , Shigeru Tsukagoshi
发明人： Fumio Mori , Masafumi Okada , Shuji Miki , Iwao Ebashi , Takashi Nishida , Kouichiro Kawai , Tazuko Tashiro , Shigeru Tsukagoshi
IPC分类号： C08B37/00
CPC分类号： C08B37/0018 , Y10S514/908
摘要： A pullulan derivative having one or more active sites resulting from introduction of sulfuric acid, phosphoric acid, a sulfonic acid or a carboxylic acid, wherein one hydrogen atom of the group of the formula ##STR1## occurring at said active sites is partly substituted by a group of the general formula ##STR2## wherein L.sup.1 and L.sup.2 each independently is amine or a unidentate ligand amine or combinedly represent a bidentate ligand amine and Y is an anionic ligand, and/or two hydrogen atoms of the group ##STR3## groups bound to one and the same carbon atom or to two neighboring carbon atoms as occurring at said active sites are, each independently, partly substituted by a group of the general formula ##STR4## wherein L.sup.1 and L.sup.2 are as defined above, and a pharmacologically acceptable salt thereof.The above compound has anticancer activity and is useful as anticancer agents.The present invention is concerned with said compound, a process for producing the same and a pharmaceutical use thereof.
摘要翻译：具有由引入硫酸，磷酸，磺酸或羧酸产生的一个或多个活性位点的支链淀粉衍生物，其中在所述活性位点发生的式“IMAGE”基团的一个氢原子部分被通式为“IMAGE”的基团，其中L1和L2各自独立地为胺或一元配体胺，或者组合表示二齿配体胺，Y为阴离子配位体，和/或组中的两个氢原子结合至在所述活性位点处发生的同一个碳原子或两个相邻的碳原子各自独立地部分地被通式“IMAGE”所示的基团取代，其中L1和L2如上所定义，及其药理学上可接受的盐。上述化合物具有抗癌活性，可用作抗癌剂。本发明涉及所述化合物，其制备方法及其药物用途。

6. 发明授权

US06494588B1 Spread illuminating apparatus with an optical path conversion means 失效
标题翻译：具有光路转换装置的扩展照明装置
公开(公告)号：US06494588B1
公开(公告)日：2002-12-17
申请号：US09606669
申请日：2000-06-30
申请人： Masafumi Okada
发明人： Masafumi Okada
IPC分类号： F21V704
CPC分类号： G02B6/0016 , G02B6/0028 , G02B6/0038 , G02B6/0061
摘要： A spread illuminating apparatus, in which a bar-like light conductive member brightened by a light emitting diode disposed at an end thereof is disposed close to the side of a transparent substrate made of light-permeable materials. The light conductive member is provided with a row of prism grooves as an optical path conversion means and an optical path conversion plate is disposed between the light conductive member and the transparent substrate. Light from the light emitting diode enters the light conductive member and is directed slantingly at the prism grooves to enter the optical path conversion means. Then, the light enters the transparent substrate straight to illuminate it efficiently.
摘要翻译：扩散照明装置，其中由设置在其一端的发光二极管增亮的棒状导光部件靠近由透光材料制成的透明基板的侧面。导光构件设置有作为光路转换装置的一排棱镜槽，并且光路转换板设置在导光构件和透明基板之间。来自发光二极管的光进入导光部件并被倾斜地指向棱镜槽以进入光路转换装置。然后，光直接进入透明基板以有效地照亮。

7. 发明授权

US08556622B2 Injection mold forming an article having a pin mounting hole 有权
标题翻译：注射模具形成具有销安装孔的制品
公开(公告)号：US08556622B2
公开(公告)日：2013-10-15
申请号：US13280958
申请日：2011-10-25
申请人： Yohei Kimita , Masafumi Okada , Hiroshi Akimoto
发明人： Yohei Kimita , Masafumi Okada , Hiroshi Akimoto
IPC分类号： B29C45/40
CPC分类号： B29C33/44 , B29C33/10
摘要： The pin mounting hole used to insert and mount the pin member having a pin-like shape is formed on, among the inner wall surfaces of the cavity, the second side-wall surface that is an inner wall surface other than the inner wall surfaces perpendicular to the mold-removal direction of the injection-molded article. On the second side-wall surface, the protruding portion protruding from the second side-wall surface is formed in the surface area located on the opposite side in the mold-removal direction with respect to the pin mounting hole.
摘要翻译：用于插入和安装具有销状形状的销构件的销安装孔形成在空腔的内壁表面之中的作为内壁表面的第二侧壁表面，内壁表面不是垂直于内壁表面到注塑制品的脱模方向。在第二侧壁面上，从与第二侧壁面突出的突出部相对于销安装孔形成在脱模方向相反一侧的表面区域。

8. 发明申请

US20060222883A1 Surface modification method for conductive metal material 审中-公开
标题翻译：导电金属材料表面改性方法
公开(公告)号：US20060222883A1
公开(公告)日：2006-10-05
申请号：US11387194
申请日：2006-03-22
申请人： Ryoji Kaku , Masafumi Okada
发明人： Ryoji Kaku , Masafumi Okada
IPC分类号： B23P9/00 , B24B39/00
CPC分类号： C21D7/00 , B24B39/006 , C21D7/06 , Y10T29/479 , Y10T428/12993
摘要： Spherical particles having curvatures larger than those of irregularities, crystal grain boundaries, lattice defects or the like (referred to collectively as irregularities, hereinafter) on the surface of a conductive metal material are ejected at high speeds to make the particles collide against the surface of the conductive metal material, thereby repeatedly causing rapid melting and cooling at the minute points of impact of the particles, thereby changing the surface into amorphous. Then, spherical particles having curvatures smaller than those of irregularities on the surface subjected to the treatment described above collide against the surface, thereby changing the surface into amorphous and planarizing the surface.
摘要翻译：导电性金属材料表面上的曲率大于不规则性，晶界，晶格缺陷等（以下统称为凹凸）的球状颗粒以高速喷射，使颗粒与导电金属材料，从而在颗粒的微小碰撞点反复引起快速熔化和冷却，从而将表面变为无定形。然后，具有小于经过上述处理的表面上的凹凸的曲率的球形颗粒与表面碰撞，从而将表面变为非晶体并使表面平坦化。

9. 发明授权

US06948400B2 Backlash clutch and joint mechanism for a robot comprising the clutch 失效
标题翻译：用于包括离合器的机器人的间隙离合器和关节机构
公开(公告)号：US06948400B2
公开(公告)日：2005-09-27
申请号：US10359726
申请日：2003-02-07
申请人： Yoshihiko Nakamura , Masafumi Okada , Tatsuya Goto
发明人： Yoshihiko Nakamura , Masafumi Okada , Tatsuya Goto
IPC分类号： B25J17/00 , B25J5/00 , B25J17/02 , B62D57/032 , F16D3/02 , F16D11/00 , F16H35/00
CPC分类号： B25J17/02 , Y10T74/20305 , Y10T74/20329 , Y10T403/32591
摘要： A backlash comprises a first rotation member and a second rotation member, each of which is provided rotatably-about the same axis, and which are engageable together in a rotating direction of the members by driving contact between respective radial extension surfaces thereof,and where a backlash gap is provided between the respective radial extension surfaces of the first and the second rotation members to permit fee rotation between the first and second rotation members in a range of the backlash gap in the rotating direction of the members.
摘要翻译：齿隙包括第一旋转构件和第二旋转构件，每个第一旋转构件和第二旋转构件可绕着相同的轴线可旋转地设置，并且通过在其各个径向延伸表面之间的驱动接触而在构件的旋转方向上可接合在一起，并且其中在第一和第二旋转构件的相应的径向延伸表面之间设置有间隙，以允许在构件的旋转方向上的间隙间隙的范围内第一和第二旋转构件之间的费用旋转。

10. 发明授权

US06334691B1 Spread illuminating apparatus 失效
标题翻译：展示照明装置
公开(公告)号：US06334691B1
公开(公告)日：2002-01-01
申请号：US09525934
申请日：2000-03-15
申请人： Shingo Suzuki , Masafumi Okada , Koichi Toyoda
发明人： Shingo Suzuki , Masafumi Okada , Koichi Toyoda
IPC分类号： F21V800
CPC分类号： G02B6/0028 , G02B6/0038 , G02B6/0046 , G02B6/0061
摘要： Between the transparent substrate 1 and the light conductive member 2 disposed along and close to at least one side end of the transparent substrate 1, the optical path conversion plate 6 having the prism portion is disposed. Due to this optical conversion plate 6, the light from the light conductive member 2 is directed effectively toward the transparent substrate 1 .
摘要翻译：在透明基板1和沿着并且靠近透明基板1的至少一个侧端的导光部件2之间设置具有棱镜部分的光路转换板6。由于该光转换板6，来自导光部件2的光有效地朝向透明基板1。

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