专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09585612B2 Multifunctional fluorescence diagnosis system 有权
标题翻译：多功能荧光诊断系统
公开(公告)号：US09585612B2
公开(公告)日：2017-03-07
申请号：US11361484
申请日：2006-02-24
申请人： Klaus M. Irion , André Ehrhardt , Reinhold Baumgartner , Herbert Stepp , Thomas Pongratz
发明人： Klaus M. Irion , André Ehrhardt , Reinhold Baumgartner , Herbert Stepp , Thomas Pongratz
IPC分类号： A61B6/00 , G01N21/64 , A61B5/00 , A61B1/00 , A61B1/04 , A61B1/06 , A61B1/307
CPC分类号： A61B5/413 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/0646 , A61B1/307 , A61B5/0071 , A61B5/0084 , A61B5/721 , G01N21/6428 , G01N21/6456
摘要： A fluorescence diagnosis system has a viewing system at least one light source and a camera system. The at least one light source can be operated in three modes, a first generating white light, a second with a first fluorescence excitation light of a first excitation wavelength and a third in which a second fluorescence excitation light of a second excitation wavelength is generated producing a fluorescence image in the NIR range. The camera system is sensitive at least in the visible and the NIR range. The system further comprises an image processing system for converting the fluorescence image in the NIR range into a visible image.
摘要翻译：荧光诊断系统具有至少一个光源和相机系统的观察系统。所述至少一个光源可以以三种模式操作，第一产生白光，第二产生具有第一激发波长的第一荧光激发光，其中第三激发光产生第二激发波长的第二荧光激发光，产生产生 NIR范围内的荧光图像。至少在可见光和近红外范围内，相机系统是敏感的。该系统还包括用于将NIR范围内的荧光图像转换成可见图像的图像处理系统。

2. 发明授权

US06212425B1 Apparatus for photodynamic diagnosis 有权
标题翻译：光动力诊断装置
公开(公告)号：US06212425B1
公开(公告)日：2001-04-03
申请号：US09043850
申请日：1998-09-18
申请人： Klaus Irion , Reinhold Baumgartner , Herbert Stepp , André Ehrhardt , Karlheinz Strobl
发明人： Klaus Irion , Reinhold Baumgartner , Herbert Stepp , André Ehrhardt , Karlheinz Strobl
IPC分类号： A61B500
CPC分类号： G01N21/6486 , A61B1/00186 , A61B1/043 , A61B1/055 , A61B1/0638 , A61B1/0646 , A61B5/0071 , A61B5/0084 , G01N21/6456
摘要： A device for “in vivo” diagnosis by means of a photosensibilisator light-induced reaction or a reaction caused by intrinsic fluorescence in biological tissue, having an illumination system, which is provided with at least one light source having a lamp system which generates incoherent light in a wavelength range of at least 380 to 680 nm, a light delivering unit which directs the light of said illumination system at the therapy and/or to-be-diagnosed tissue area, and an imaging, image-recording and image-transmitting unit which images the light coming from said tissue area in a proximal image plane. The device is distinguished in that the net spectral transmittance in the light delivering unit and in the image-generating unit of the device are selected in such a manner that, on the one hand, practically no light with a wavelength of &lgr; from the range utilized for excitation, which by nature has relatively high intensity, “reaches” via the image-generating unit of the device into the proximal image plane, whereas light with a wavelength of &lgr; from the range in which fluorescence occurs can reach the proximal image plane only if it comes from the illuminated tissue are and not from the illumination system.
摘要翻译：一种用于通过光敏效应器光诱导反应或由生物组织中的固有荧光引起的反应进行的“体内”诊断的装置，具有照明系统，其具有至少一个具有产生不相干光的灯系统的光源在至少380至680nm的波长范围内，将所述照明系统的光引导到治疗和/或待诊断的组织区域的光输送单元，以及成像，图像记录和图像发送单元其在近端图像平面中对来自所述组织区域的光进行成像。该装置的特征在于，以这样的方式选择装置中的光输送单元和图像生成单元中的净光谱透射率，一方面实际上不具有从所使用的范围的羔羊波长的光对于本质上具有相对高强度的激发，通过装置的图像生成单元“到达”到近端图像平面中，而从发生荧光的范围的波长为lamb的光可以仅到达近端图像平面如果它来自照明组织而不是来自照明系统。

3. 发明申请

US20060241499A1 Multifunctional fluorescence diagnosis system 有权
标题翻译：多功能荧光诊断系统
公开(公告)号：US20060241499A1
公开(公告)日：2006-10-26
申请号：US11361484
申请日：2006-02-24
申请人： Klaus Irion , Andre Ehrhardt , Reinhold Baumgartner , Herbert Stepp , Thomas Pongratz
发明人： Klaus Irion , Andre Ehrhardt , Reinhold Baumgartner , Herbert Stepp , Thomas Pongratz
IPC分类号： A61B6/00
CPC分类号： A61B5/413 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/0646 , A61B1/307 , A61B5/0071 , A61B5/0084 , A61B5/721 , G01N21/6428 , G01N21/6456
摘要： A fluorescence diagnosis system has a viewing system at least one light source and a camera system. The at least one light source can be operated in three modes, a first generating white light, a second with a first fluorescence excitation light of a first excitation wavelength and a third in which a second fluorescence excitation light of a second excitation wavelength is generated producing a fluorescence image in the NIR range. The camera system is sensitive at least in the visible and the NIR range. The system further comprises an image processing system for converting the fluorescence image in the NIR range into a visible image.
摘要翻译：荧光诊断系统具有至少一个光源和相机系统的观察系统。所述至少一个光源可以以三种模式操作，第一产生白光，第二产生具有第一激发波长的第一荧光激发光，其中第三激发光产生第二激发波长的第二荧光激发光，产生产生 NIR范围内的荧光图像。至少在可见光和近红外范围内，相机系统是敏感的。该系统还包括用于将NIR范围内的荧光图像转换成可见图像的图像处理系统。

4. 发明授权

US06510338B1 Method of and devices for fluorescence diagnosis of tissue, particularly by endoscopy 有权
标题翻译：用于组织荧光诊断的方法和装置，特别是通过内窥镜检查
公开(公告)号：US06510338B1
公开(公告)日：2003-01-21
申请号：US09633696
申请日：2000-08-07
申请人： Klaus M. Irion , André Erhardt , Herbert Stepp , Josef Peter Pichler
发明人： Klaus M. Irion , André Erhardt , Herbert Stepp , Josef Peter Pichler
IPC分类号： A61B500
CPC分类号： A61B1/043 , A61B1/00186 , A61B1/05 , A61B1/0638 , A61B1/0646 , A61B5/0071 , A61B5/0084
摘要： A method of and a device for the endoscopic fluorescence diagnosis of tissue, wherein the tissue is exposed to stimulating light via an endoscope for stimulation of fluorescence, which stimulating light is suitable, on account of its spectral distribution, to stimulate at least two different fluorescence modes in the tissue without filter switching in the stimulation beam path, and wherein the fluorescence light of the different fluorescence modes can be selectively observed.
摘要翻译：一种用于组织内窥镜荧光诊断的方法和装置，其中由于其光谱分布，组织暴露于经由内窥镜刺激光的刺激光，刺激光是适合的，以刺激至少两种不同的荧光刺激光束路径中没有滤波器切换的组织中的模式，并且其中可以选择性地观察不同荧光模式的荧光。

5. 发明授权

US07794388B2 Method and apparatus for generating at least one section of a virtual 3D model of a body interior 有权
标题翻译：用于产生身体内部的虚拟3D模型的至少一个部分的方法和装置
公开(公告)号：US07794388B2
公开(公告)日：2010-09-14
申请号：US11503196
申请日：2006-08-11
申请人： Wolfgang Draxinger , Margarita Noll , Herbert Stepp , Klaus M. Irion
发明人： Wolfgang Draxinger , Margarita Noll , Herbert Stepp , Klaus M. Irion
IPC分类号： A61B1/00
CPC分类号： A61B5/1077 , A61B1/00009 , A61B1/042 , A61B5/065 , A61B8/12 , A61B34/20 , A61B90/361 , A61B2034/105 , A61B2034/2048 , A61B2034/2051
摘要： A method for generating at least one section of a virtual 3D model of a body interior, in particular a hollow organ, uses data that are provided by at least one endoscope introduced into the body interior. The data comprise at least one position and orientation of the endoscope, the at least one position and orientation being assigned at least one distance between the endoscope and the at least one point on a surface of the body interior, and at least one endoscopic image of the surface of the body interior in the region of the at least one point on the surface of the body interior. From the said data relating to a number of different positions and orientations of the endoscope is/are generated the section or sections of the 3D model in superposition with the associated endoscopic image. An appropriate apparatus is also described.
摘要翻译：用于产生身体内部，特别是中空器官的虚拟3D模型的至少一个部分的方法使用由引入到身体内部的至少一个内窥镜提供的数据。所述数据包括所述内窥镜的至少一个位置和取向，所述至少一个位置和取向被分配在所述内窥镜与所述主体内部的表面上的所述至少一个点之间的至少一个距离，以及至少一个内窥镜图像在身体内部的表面上的至少一个点的区域中的身体内部的表面。从与所述内窥镜的多个不同位置和取向相关的所述数据生成与相关联的内窥镜图像重叠的3D模型的部分或部分。还描述了适当的装置。

6. 发明授权

US06640131B1 Device for photodynamic diagnosis or treatment 有权
标题翻译：用于光动力学诊断或治疗的装置
公开(公告)号：US06640131B1
公开(公告)日：2003-10-28
申请号：US09242709
申请日：2001-03-14
申请人： Klaus M. Irion , Herbert Stepp , Andre Erhardt , Hans Tafelmaier
发明人： Klaus M. Irion , Herbert Stepp , Andre Erhardt , Hans Tafelmaier
IPC分类号： A61B500
CPC分类号： A61B5/0084 , A61B5/0071
摘要： An endoscopic or microscopic apparatus for diagnosis by means of a light-induced reaction in biologic tissue “in vivo” which is created by a photo-amboceptor or by autofluorescence is provided. The inventive apparatus is characterized by the feature that at least one reference wavelength &lgr;r is provided which is longer by up to 2&Dgr;&lgr; at maximum or smaller than the wavelength &lgr;s at the point of intersection.
摘要翻译：提供了一种用于通过由光敏受体或自发荧光产生的“体内”生物组织中的光诱导反应进行诊断的内窥镜或微观装置。本发明的装置的特征在于提供了至少一个参考波长兰波尔，其在距离交点处最多或小于波长兰波斯时长达2Deltalambda。

7. 发明授权

US4920541A Apparatus for generating various laser wavelengths from the same laser medium 失效
标题翻译：用于从相同激光介质产生各种激光波长的装置
公开(公告)号：US4920541A
公开(公告)日：1990-04-24
申请号：US357654
申请日：1989-05-25
申请人： Reinhold Baumgartner , Hans Lenz , Herbert Stepp , Eberhard Unsold
发明人： Reinhold Baumgartner , Hans Lenz , Herbert Stepp , Eberhard Unsold
IPC分类号： H01S3/08 , H01S3/082
CPC分类号： H01S3/082 , H01S3/08004 , H01S3/08086 , H01S3/107
摘要： An apparatus for producing various laser wavelengths from the same laser medium by means of resonator mirrors. In accordance with the apparatus any desired, given combination of laser wavelengths can be brought to emission simultaneously or at least in very rapid alternation (switching time 1 ms) with the use of standard resonator mirrors linearly arranged outside of a laser medium, with part of at least one of the resonator mirrors being configured so that it serves as resonator limitation for a certain laser wavelength or wavelength group but another part of the at least one of the resonator mirrors constitutes an intracavity element for the respective other wavelength(s) or wavelength group(s).
摘要翻译：一种用于通过谐振器反射镜从同一激光介质产生各种激光波长的装置。根据该装置，任何期望的，给定的激光波长的组合可以同时或至少以非常快速的交替（切换时间1ms）发射，使用线性布置在激光介质外部的标准谐振镜，其中一部分谐振器反射镜中的至少一个被配置为使得其用作特定激光波长或波长组的谐振器限制，但是至少一个谐振器反射镜的另一部分构成用于各个其它波长或波长的腔内元件组。

8. 发明授权

US08520919B2 Apparatus and method for controlling a multi-color output of an image of a medical object 有权
标题翻译：用于控制医疗物体的图像的多色输出的装置和方法
公开(公告)号：US08520919B2
公开(公告)日：2013-08-27
申请号：US12817646
申请日：2010-06-17
申请人： Herbert Stepp , Hilmar Schachenmayr
发明人： Herbert Stepp , Hilmar Schachenmayr
IPC分类号： G06K9/00 , A61B1/04 , A61B1/06 , A61B6/00 , H04N15/00 , H04N3/14 , H04N9/04 , G01J5/02
CPC分类号： A61B1/0638 , A61B1/043 , A61B1/0646
摘要： In a method for controlling a multi-color output of an image of a medical object for assisting medical personnel, the medical object is illuminated with light with an illumination spectrum. By means of an image sensor, image data are acquired for a group of one or more color channels. Image information concerning an additional color channel, which is not among the group of one or more color channels, is generated depending on the acquired image data. An image output device for multi-color output of the image is controlled depending on the acquired image data and the acquired image information.
摘要翻译：在用于控制用于辅助医疗人员的医疗物体的图像的多色输出的方法中，用具有照明光谱的光照射医疗物体。通过图像传感器，针对一组或多个颜色通道获取图像数据。根据获取的图像数据生成关于不在一个或多个颜色通道的组中的附加颜色通道的图像信息。用于图像的多色输出的图像输出装置根据获取的图像数据和所获取的图像信息进行控制。

9. 发明申请

US20070053204A1 Confocal microendoscope comprising optical fibres with a tapering diameter 审中-公开
标题翻译：共焦显微镜，包括具有锥形直径的光纤
公开(公告)号：US20070053204A1
公开(公告)日：2007-03-08
申请号：US10573141
申请日：2004-09-10
申请人： Ingo Krohne , Andre Ehrhardt , Klaus Irion , Herbert Stepp
发明人： Ingo Krohne , Andre Ehrhardt , Klaus Irion , Herbert Stepp
IPC分类号： A61B3/00 , A61B1/06 , G03B29/00 , G03B15/02 , G02B6/06 , F21V5/00
CPC分类号： A61B5/0068 , A61B5/0084 , G02B21/0028 , G02B23/2461
摘要： The invention relates to a confocal microendoscope, in which the diameter of optical fibres at the proximal end (8) of an optical fibre bundle (9) is greater than at the distal end (15). This permits the efficiency of coupling the light of a light source to be increased, without reducing the resolution of the microendoscope. In addition, the proximal ends (8) of the optical fibres (10) are arranged in a grid, for example, by means of a fibre receiving unit (11) that holds the individual optical fibres. A microlens unit (13) can also be provided, said unit allocating a microlens (14) to each optical fibre end.
摘要翻译：本发明涉及一种共焦显微镜，其中光纤束（9）的近端（8）处的光纤的直径大于远端（15）处的光纤直径。这允许在不降低微内镜的分辨率的情况下增加耦合光源的光的效率。此外，光纤（10）的近端（8）例如通过保持各个光纤的光纤接收单元（11）布置成格栅。还可以设置微透镜单元（13），所述单元向每个光纤端分配微透镜（14）。

10. 发明授权

US11490816B2 Apparatus and method for fluorescence measurements on tissue for the determination of blood fluorophores 有权
公开(公告)号：US11490816B2
公开(公告)日：2022-11-08
申请号：US15551303
申请日：2016-02-17
申请人： Herbert Stepp , Georg Hennig , Christian Homann
发明人： Herbert Stepp , Georg Hennig , Christian Homann , Gary M. Brittenham , Michael Grossman
IPC分类号： A61B5/1455 , A61B5/00 , G01N21/31 , G01N21/49 , G01N21/64 , A61B5/145
摘要： The present invention is directed to an apparatus (10) for reliable quantitative measurement of a fluorescent blood analyte in tissue (12) comprising: at least one light source (14), the light source (14) emitting excitation light at least at a first wavelength range between 350 nm and 450 nm to the tissue (12); a detection unit (16), the detection unit (16) measuring: a) a portion of the fluorescent light emitted by the fluorescent blood analyte excited at the first wavelength range; and b) a portion of the auto fluorescence emitted by the tissue (12); and/or c1) a portion of the remitted excitation light at the first wavelength range, and c2) a portion of the remitted light at a second wavelength range; and a control unit (18), the control unit (18) operating the light source (14) and detection unit (16). The present invention is further directed to a method for quantitative measurement of a fluorescent blood analyte in tissue (12).

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式