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1. 发明申请

US20050131336A1 Electrode structure 审中-公开
标题翻译：电极结构
公开(公告)号：US20050131336A1
公开(公告)日：2005-06-16
申请号：US10501948
申请日：2003-01-23
申请人： Kenji Mori , Hiroyuki Maeda , Yoshihiro Nishi , Tetsuya Arimoto , Naruhito Higo , Shuji Sato , Tatsuya Ogawa , Saori Takahashi , Yasushi Fuchita
发明人： Kenji Mori , Hiroyuki Maeda , Yoshihiro Nishi , Tetsuya Arimoto , Naruhito Higo , Shuji Sato , Tatsuya Ogawa , Saori Takahashi , Yasushi Fuchita
IPC分类号： A61N1/04 , A61N1/30
CPC分类号： A61N1/0492 , A61N1/0412 , A61N1/0428 , A61N1/0496
摘要： An electrode structure is provided which is capable of efficiently using a material that can be a non-polarized electrode component, allowing the material to fully demonstrate the effect as the non-polarized electrode and maintaining the performance. This electrode structure comprises an insulating base (13), a polarized component layer (first layer) (12) laminated on the insulating base so as not to penetrate the insulating base, the polarized component layer comprising a conductive paste or metallic foil which is predominantly made of a component that can be a polarized electrode, and a non-polarized component layer (second layer) (11) provided on the polarized component layer, the non-polarized component layer comprising a conductive paste which is predominantly made of a component that can be a non-polarized electrode.
摘要翻译：提供一种电极结构，其能够有效地使用可以是非极化电极组分的材料，从而允许材料充分显示作为非极化电极的作用并保持性能。该电极结构包括绝缘基底（13），层叠在绝缘基底上的极化部件层（第一层）（12），以便不穿透绝缘基底，所述偏振构件层包括导电膏或金属箔，其主要是由可以是极化电极的部件和设置在偏振部件层上的非偏振部件层（第二层）（11）构成，非极化部件层包括主要由以下部件构成的导电膏可以是非极化电极。

2. 发明申请

US20050085887A1 Electrode structural body 审中-公开
标题翻译：电极结构体
公开(公告)号：US20050085887A1
公开(公告)日：2005-04-21
申请号：US10505158
申请日：2003-02-19
申请人： Kenji Mori , Hiroyuki Maeda , Tatsuya Ogawa , Saori Takahashi , Yoshihiro Nishi , Tetsuya Arimoto , Naruhito Higo , Shuji Sato , Yasushi Fuchita
发明人： Kenji Mori , Hiroyuki Maeda , Tatsuya Ogawa , Saori Takahashi , Yoshihiro Nishi , Tetsuya Arimoto , Naruhito Higo , Shuji Sato , Yasushi Fuchita
IPC分类号： A61N1/04 , A61N1/30
CPC分类号： A61N1/0424 , A61N1/044
摘要： There is provided an electrode structure in which cracks are hardly generated in the bending processed portions, in particular, in the electrode layer and the insulating layer. The electrode structure comprises a support (3) having bending processed portions (4), an electrode layer (1) formed on the support so as to pass over the bending processed portions (4), and an insulating layer (2) formed on the electrode layer (1) passing over the bending processed portions (4). The glass transition temperature of the dielectric material forming the insulating layer (2) is made to be 25° C. or below. The electrode layer (1) includes at least one material belonging to the group consisting of silver, silver chloride and carbon, and in particular, a terminal portion (5) of the electrode layer (1) passing over the bending processed portions (4) is formed of a paste containing carbon as the main component.
摘要翻译：提供了一种在弯曲加工部分，特别是在电极层和绝缘层中几乎不产生裂纹的电极结构。电极结构包括具有弯曲加工部分（4）的支撑件（3），形成在支撑件上以便穿过弯曲加工部分（4）的电极层（1），以及形成在经过弯曲处理部分（4）的电极层（1）。形成绝缘层（2）的电介质材料的玻璃化转变温度为25℃以下。电极层（1）包括属于由银，氯化银和碳组成的组中的至少一种材料，特别是通过弯曲加工部分（4）的电极层（1）的端子部分（5）由以碳为主要成分的糊状物形成。

3. 发明申请

US20050113738A1 Iontophoresis electrode device 审中-公开
标题翻译：离子电渗电极装置
公开(公告)号：US20050113738A1
公开(公告)日：2005-05-26
申请号：US10500537
申请日：2003-01-09
申请人： Yasushi Fuchita , Tatsuya Ogawa , Saori Takahashi , Takuji Oikawa , Shuji Sato , Naruhito Higo , Hiroyuki Maeda , Kenji Mori
发明人： Yasushi Fuchita , Tatsuya Ogawa , Saori Takahashi , Takuji Oikawa , Shuji Sato , Naruhito Higo , Hiroyuki Maeda , Kenji Mori
IPC分类号： A61N1/30
CPC分类号： A61N1/0436 , A61N1/044
摘要： There is provided an electrode device for iontophoresis capable of retaining a drug in a gel state with a force just enough so as not to disturb the treatment. In order to retain the gel (70), a sheet member (50) composed of a nonwoven fabric is laminated on a base film (20) including an electrode layer (30) so as to be integrated with the base film (20). The sheet member (50) has a property for allowing the gel (70) to permeate therein. Owing to this feature, the gel (70) loaded on the sheet member (50) is retained thereon with at least a part of the gel (70) permeated therein.
摘要翻译：提供了一种用于离子电渗疗法的电极装置，其能够以刚好足够的力将药物保持在凝胶状态，以免扰乱治疗。为了保持凝胶（70），将由非织造织物构成的片材（50）层叠在包含电极层（30）的基膜（20）上以与基膜（20）一体化。片材（50）具有使凝胶（70）渗透到其中的性质。由于这个特征，装载在片材（50）上的凝胶（70）保留在其上，凝胶（70）的至少一部分渗入其中。

4. 发明授权

US07502654B2 Electrode device having recessed part 失效
标题翻译：具有凹部的电极装置
公开(公告)号：US07502654B2
公开(公告)日：2009-03-10
申请号：US10517535
申请日：2003-06-11
申请人： Kenji Mori , Hiroyuki Maeda , Naruhito Higo , Shuji Sato , Yasushi Fuchita , Tatsuya Ogawa , Saori Takahashi
发明人： Kenji Mori , Hiroyuki Maeda , Naruhito Higo , Shuji Sato , Yasushi Fuchita , Tatsuya Ogawa , Saori Takahashi
IPC分类号： A61N1/00
CPC分类号： A61N1/0492 , A61B2562/187 , A61N1/0424 , A61N1/044 , A61N1/0448
摘要： The invention provides an electrode device that prevents disconnection of an electrode layer effectively by reducing stress at the time when a recess is formed.An electrode device (10) has a protrusion (70), which projects upward, in the part of an outward flange section (110f), other than a recess (60) formed by molding. The protrusion (70) is arranged so as to surround an outer periphery of the recess (60). When the recess (60) is cold-pressed, the protrusion (70) prevents warp (warp waving along a peripheral direction) in the outward flange section (110f) from occurring. Consequently, the protrusion (70) also eases warp of an electrode layer (30) extending on the outward flange section (110f) and prevents disconnection of the electrode layer (30).
摘要翻译：本发明提供一种电极装置，其通过在形成凹部时减少应力来有效地防止电极层的断开。电极装置（10）具有在外部凸缘部（110f）的不同于通过模制形成的凹部（60）的一部分中向上方突出的突起（70）。突出部70配置成包围凹部60的外周。当凹部（60）被冷压时，突起（70）防止在向外的凸缘部（110f）中发生翘曲（沿周向的翘曲）。因此，突起（70）也可以缓和在外侧凸缘部（110f）上延伸的电极层（30）的翘曲，防止电极层（30）断开。

5. 发明申请

US20060206186A1 Electrode device having recessed part 失效
标题翻译：具有凹部的电极装置
公开(公告)号：US20060206186A1
公开(公告)日：2006-09-14
申请号：US10517535
申请日：2003-06-11
申请人： Kenji Mori , Hiroyuki Maeda , Naruhito Higo , Shuji Sato , Yasushi Fuchita , Tatsuya Ogawa , Saori Takahashi
发明人： Kenji Mori , Hiroyuki Maeda , Naruhito Higo , Shuji Sato , Yasushi Fuchita , Tatsuya Ogawa , Saori Takahashi
IPC分类号： A61N1/04
CPC分类号： A61N1/0492 , A61B2562/187 , A61N1/0424 , A61N1/044 , A61N1/0448
摘要： The invention provides an electrode device that prevents disconnection of an electrode layer effectively by reducing stress at the time when a recess is formed. An electrode device (10) has a protrusion (70), which projects upward, in the part of an outward flange section (110f), other than a recess (60) formed by molding. The protrusion (70) is arranged so as to surround an outer periphery of the recess (60). When the recess (60) is cold-pressed, the protrusion (70) prevents warp (warp waving along a peripheral direction) in the outward flange section (110f) from occurring. Consequently, the protrusion (70) also eases warp of an electrode layer (30) extending on the outward flange section (110f) and prevents disconnection of the electrode layer (30).
摘要翻译：本发明提供一种电极装置，其通过在形成凹部时减少应力来有效地防止电极层的断开。电极装置（10）具有突出部（70），该突起部（70）在除了通过模制形成的凹部（60）之外的向外的凸缘部分（110f）的一部分中向上突出。突出部70配置成包围凹部60的外周。当凹部（60）被冷压时，突起（70）防止在向外的凸缘部（110f）中的翘曲（沿着周向的翘曲）发生。因此，突起（70）还可以缓和在外侧凸缘部（110f）上延伸的电极层（30）的翘曲，并防止电极层（30）断开。

6. 发明授权

US07005784B2 Electrode apparatus for preventing cracking of the electrode and insulating layers 失效
标题翻译：用于防止电极和绝缘层破裂的电极装置
公开(公告)号：US07005784B2
公开(公告)日：2006-02-28
申请号：US10650195
申请日：2003-08-27
申请人： Tatsuya Ogawa , Saori Takahashi , Yasushi Fuchita , Kenji Mori , Naruhito Higo
发明人： Tatsuya Ogawa , Saori Takahashi , Yasushi Fuchita , Kenji Mori , Naruhito Higo
IPC分类号： H01J1/00
CPC分类号： A61N1/0492 , A61N1/0428 , A61N1/0448
摘要： It is an object of the invention to prevent not only cracking but also blocking of an electrode layer 20 and an electrically insulating layer 30, particularly the electrically insulating layer 30, which is formed on a base film 10. An electrode apparatus comprises a base film 10 for defining a recess 50 at the inner periphery of a bending part 500, and an electrode layer 20 and an electrically insulating layer 30 which are pattern formed on the base film 10. The electrode layer 20 crosses the bending part 500 from the inside of the recess 50 to the outside. The electrically insulating layer 30 covers the upper part of the electrode layer 20 in the vicinity of the bending part 500. A resin composition obtained by admixing a low Tg resin having a glass transition temperature equal to 25 degrees C. or lower and a high Tg resin having a higher glass transition temperature (for example, 40 degrees C. or higher) than that of the low Tg resin is used as a dielectric of the electrically insulating layer 30.
摘要翻译：本发明的一个目的是防止在底膜10上形成的电极层20和电绝缘层30，特别是电绝缘层30的破裂，而且阻止。电极装置包括：基膜10，用于在弯曲部500的内周形成凹部50，在基膜10上形成图案形成的电极层20和电绝缘层30。电极层20从凹部50的内部与弯曲部500交叉。电绝缘层30在弯曲部500附近覆盖电极层20的上部。将玻璃化转变温度为25℃以下的低Tg树脂和玻璃化转变温度（例如40℃以上）的高Tg树脂混合而得到的树脂组合物 Tg树脂用作电绝缘层30的电介质。

7. 发明申请

US20050174029A1 Electrode apparatus 失效
标题翻译：电极装置
公开(公告)号：US20050174029A1
公开(公告)日：2005-08-11
申请号：US10650195
申请日：2003-08-27
申请人： Tatsuya Ogawa , Saori Takahashi , Yasushi Fuchita , Kenji Mori , Naruhito Higo
发明人： Tatsuya Ogawa , Saori Takahashi , Yasushi Fuchita , Kenji Mori , Naruhito Higo
IPC分类号： A61B5/0408 , A61N1/04 , A61N1/30 , H01J1/00
CPC分类号： A61N1/0492 , A61N1/0428 , A61N1/0448
摘要： It is an object of the invention to prevent not only cracking but also blocking of an electrode layer 20 and an electrically insulating layer 30, particularly the electrically insulating layer 30, which is formed on a base film 10. An electrode apparatus comprises a base film 10 for defining a recess 50 at the inner periphery of a bending part 500, and an electrode layer 20 and an electrically insulating layer 30 which are pattern formed on the base film 10. The electrode layer 20 crosses the bending part 500 from the inside of the recess 50 to the outside. The electrically insulating layer 30 covers the upper part of the electrode layer 20 in the vicinity of the bending part 500. A resin composition obtained by admixing a low Tg resin having a glass transition temperature equal to 25 degrees C. or lower and a high Tg resin having a higher glass transition temperature (for example, 40 degrees C. or higher) than that of the low Tg resin is used as a dielectric of the electrically insulating layer 30.
摘要翻译：本发明的目的是不仅防止在基膜10上形成的电极层20和电绝缘层30，特别是电绝缘层30的破裂而且阻塞。电极装置包括基膜用于在弯曲部500的内周形成凹部50的电极层20以及形成在基膜10上的图案形成的电极层20和电绝缘层30.电极层20从弯曲部500的内侧穿过弯曲部500 凹部50到外面。电绝缘层30覆盖弯曲部500附近的电极层20的上部。通过将玻璃化转变温度等于或等于25℃的玻璃化转变温度等于或低于25℃的高Tg树脂与高Tg 作为电绝缘层30的电介质，使用具有比低Tg树脂更高的玻璃化转变温度（例如40℃以上）的树脂。

8. 发明申请

US20070129664A1 Electrode chip for biological application and its using method 有权
标题翻译：用于生物应用的电极芯片及其使用方法
公开(公告)号：US20070129664A1
公开(公告)日：2007-06-07
申请号：US10579287
申请日：2004-10-22
申请人： Yasushi Fuchita , Tatsuya Ogawa , Saori Takahashi , Mitsuru Kuribayashi , Naruhito Higo
发明人： Yasushi Fuchita , Tatsuya Ogawa , Saori Takahashi , Mitsuru Kuribayashi , Naruhito Higo
IPC分类号： A61N1/30
CPC分类号： A61N1/0448 , A61N1/044
摘要： This invention relates to a technology for preventing leakage of liquid from gel (70). The electrode chip (10) comprises a cup-like support (20) including a cup part (210), and a sheet-like support (30) attached with an electrode layer (40). The gel (70) in the cup part (210) delivers liquid (700) containing water confined at the time of crosslinking. The liquid (700) moves by capillarity from the gel (70) side through a narrow gap between the outer flange (220) of the cup-like support (20) and the outside part (310o) of the sheet-like support (30) in a direction away from the gel (70). Since a groove (80) exists in the vicinity of the cup part (210) and the gap is large at that part, capillarity is broken thereat.
摘要翻译：本发明涉及防止液体从凝胶（70）泄漏的技术。电极芯片（10）包括一个包括一个杯形部分（210）的杯状支撑件（20）和一个安装有电极层（40）的片状支撑件（30）。杯部（210）中的凝胶（70）输送含有交联时限制的水的液体（700）。液体（700）通过毛细管作用从凝胶（70）侧通过杯形支撑件（20）的外凸缘（220）与片状支撑件（310）的外部（310o）之间的窄间隙移动 30）沿远离凝胶（70）的方向。由于在杯部（210）附近存在凹槽（80），并且在该部分处间隙大，所以毛细管损坏。

9. 发明授权

US07483737B2 Electrode chip for biological application and its using method 有权
标题翻译：用于生物应用的电极芯片及其使用方法
公开(公告)号：US07483737B2
公开(公告)日：2009-01-27
申请号：US10579287
申请日：2004-10-22
申请人： Yasushi Fuchita , Tatsuya Ogawa , Saori Takahashi , Mitsuru Kuribayashi , Naruhito Higo
发明人： Yasushi Fuchita , Tatsuya Ogawa , Saori Takahashi , Mitsuru Kuribayashi , Naruhito Higo
IPC分类号： A61N1/30
CPC分类号： A61N1/0448 , A61N1/044
摘要： This invention relates to a technology for preventing leakage of liquid from gel (70). The electrode chip (10) comprises a cup-like support (20) including a cup part (210), and a sheet-like support (30) attached with an electrode layer (40). The gel (70) in the cup part (210) delivers liquid (700) containing water confined at the time of crosslinking. The liquid (700) moves by capillarity from the gel (70) side through a narrow gap between the outer flange (220) of the cup-like support (20) and the outside part (310o) of the sheet-like support (30) in a direction away from the gel (70). Since a groove (80) exists in the vicinity of the cup part (210) and the gap is large at that part, capillarity is broken thereat.
摘要翻译：本发明涉及防止液体从凝胶（70）泄漏的技术。电极芯片（10）包括一个包括一个杯形部分（210）的杯状支撑件（20）和一个安装有电极层（40）的片状支撑件（30）。杯部（210）中的凝胶（70）输送含有交联时限制的水的液体（700）。液体（700）通过毛细管作用从凝胶（70）侧通过杯形支撑件（20）的外凸缘（220）与片状支撑件（30）的外部部分（310o）之间的窄间隙移动）沿远离凝胶（70）的方向。由于在杯部（210）附近存在凹槽（80），并且在该部分处间隙大，所以毛细管损坏。

10. 发明申请

US20050085860A1 Transdermal/transmucosal preparations for electroporation 审中-公开
标题翻译：用于电穿孔的透皮/透粘膜制剂
公开(公告)号：US20050085860A1
公开(公告)日：2005-04-21
申请号：US10501946
申请日：2003-01-20
申请人： Kenji Mori , Seiji Tokumoto , Naruhito Higo , Shuji Sato , Kenji Sugibayashi
发明人： Kenji Mori , Seiji Tokumoto , Naruhito Higo , Shuji Sato , Kenji Sugibayashi
IPC分类号： A61K9/70 , A61K31/05 , A61K31/155 , A61K31/192 , A61K31/196 , A61K31/375 , A61K47/36 , A61N1/30 , A61P25/04 , A61P39/06 , A61P43/00
CPC分类号： A61N1/30
摘要： A preparation for transdermal or transmucosal administration for electroporation is provided that enables efficient administration of a compound to be administered such as a drug. The preparation for transdermal or transmucosal administration for electroporation includes a drug reservoir (11) having dispersed therein a compound to be administered (physiologically active substance), such as a drug, in a base of a solid or semisolid form, a backing (12) retaining the drug reservoir, and a pair of electrodes for electroporation (13) provided on the drug reservoir (11). An adhesive layer (14) is provided on a flange portion of the backing (12). An insulating layer (15) is provided on at least a section of the electrodes for electroporation (13) contacting an application site other than a section on the drug reservoir (11).
摘要翻译：提供了用于电穿孔的经皮或经粘膜给药的制剂，其能够有效施用待给药的化合物例如药物。透皮或经粘膜给药用于电穿孔的制剂包括其中分散有固体或半固体形式的基质中的待给药化合物（生理活性物质）如药物的药物储存器（11），背衬（12）保持药物储存器和设置在药物储存器（11）上的一对用于电穿孔的电极（13）。粘合剂层（14）设置在背衬（12）的凸缘部分上。绝缘层（15）设置在用于电穿孔（13）的电极的至少一部分上，接触除了药物储存器（11）上的部分之外的施用部位。

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