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    • 9. 发明授权
    • Gas-liquid two-phase flow chromatographic analyzer and method of analysis using the same analyzer
    • 气液二相流色谱分析仪及分析方法采用相同的分析仪
    • US07827850B2
    • 2010-11-09
    • US11910045
    • 2006-03-31
    • Isao Tanikawa
    • Isao Tanikawa
    • G01N1/00
    • G01N30/6069G01N27/62G01N30/34G01N30/462G01N2030/065
    • This invention provides a chromatographic apparatus comprising an introduction part for a carrier gas as a main mobile phase medium, a sample injection part, a separation column comprising a stationary phase formed by coating a polymeric material, a part for housing the separation column, and a detector. The sample injection part is provided between the carrier gas introduction part and the inlet of the separation column. The chromatographic apparatus further comprises a solvent introduction means for adding a liquid solvent as a second mobile phase medium to a carrier gas and mixing them together, a mechanism for regulating the amount of the carrier gas introduced and the amount of the solvent added, and a mechanism for regulating the temperature of each flow passage. A plurality of clogging liquid stoppers, of which the liquid film thickness is equal to the inner diameter of a capillary column, are partly provided at predetermined intervals within the column in a longitudinal direction of the column. In such a state that a gas phase and a liquid phase are intermittently alternated, a mobile phase medium is moved toward a column outlet and a sample is separated by utilizing distribution between the solvent liquid film of the mobile phase medium and the column stationary phase. There is also provided a chromatographic analytical method utilizing this apparatus. According to this method, a sample can be separated without using any high pressure pump.
    • 本发明提供一种色谱装置,其特征在于,包括作为载体气体作为主要流动相介质的引入部分,样品注入部分,包含通过涂覆聚合物材料形成的固定相的分离柱,用于容纳分离柱的部分, 探测器。 样品注入部设置在载气导入部和分离塔的入口之间。 色谱装置还包括溶剂引入装置,用于将液体溶剂作为第二流动相介质添加到载气并将它们混合在一起,用于调节引入的载气量和添加的溶剂量的机构,以及 用于调节每个流道温度的机构。 其中液膜厚度等于毛细管柱的内径的多个堵塞液塞在柱的长度方向上以规定间隔部分设置。 在气相和液相间歇地交替的状态下,通过流动相介质的溶剂液膜和柱固定相之间的分布,使流动相介质向列出口移动,样品分离。 还提供了利用该装置的色谱分析方法。 根据该方法,可以在不使用任何高压泵的情况下分离样品。