专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5138059A DC-89 compounds and process for their preparation 失效
标题翻译： DC-89化合物及其制备方法
公开(公告)号：US5138059A
公开(公告)日：1992-08-11
申请号：US380379
申请日：1989-07-17
申请人： Keiichi Takahashi , Michio Ichimura , Shigeo Katsumata , Tatsuhiro Ogawa , Makoto Morimoto , Tadashi Ashizawa , Masaji Kasai , Kenichi Muroi , Hiromitsu Saito , Hiroshi Sano , Toru Yasuzawa
发明人： Keiichi Takahashi , Michio Ichimura , Shigeo Katsumata , Tatsuhiro Ogawa , Makoto Morimoto , Tadashi Ashizawa , Masaji Kasai , Kenichi Muroi , Hiromitsu Saito , Hiroshi Sano , Toru Yasuzawa
IPC分类号： C12P17/18 , A61K31/40 , A61K31/435 , A61P31/04 , A61P35/00 , C07D471/04 , C07D487/04 , C12N1/20 , C12R1/465
CPC分类号： C07D471/04 , C07D487/04
摘要： Novel DC-89 compounds represented by the general formula: ##STR1## wherein X represents a single bond or --CH.sub.2 --; and when X represents a single bond, Y represents --CH.sub.2 Br or --CH.sub.2 Cl and when X represents --CH.sub.2 --, Y represents Br, are obtained by the present invention. The compounds have antibacterial and anti-tumor activity.

2. 发明授权

US4563462A Substance AX-2, a process for producing the same and an antitumor composition containing the same 失效
标题翻译： AX-2物质，其制备方法和含有该物质的抗肿瘤剂组合物
公开(公告)号：US4563462A
公开(公告)日：1986-01-07
申请号：US546142
申请日：1983-10-27
申请人： Shinzo Ishii , Shigeo Katsumata , Yuko Arai , Tadashi Ashizawa , Makoto Morimoto , Kunikatsu Shirahata , Yutaka Saito , Motomichi Kono
发明人： Shinzo Ishii , Shigeo Katsumata , Yuko Arai , Tadashi Ashizawa , Makoto Morimoto , Kunikatsu Shirahata , Yutaka Saito , Motomichi Kono
IPC分类号： A61K31/47 , A61P35/00 , A61P35/02 , C07D471/16 , C12P17/18 , C12R1/465
CPC分类号： C07D471/16 , C12P17/182 , C12R1/465
摘要： A substance designated by us as AX-2 and represented by the formula: ##STR1## This substance is produced by culturing a microorganism of the genus Streptomyces and capable of producing AX-2 in a medium to accumulate AX-2 in the cultured broth and isolating AX-2 therefrom.An anti-tumor composition comprising an effective amount of AX-2 in association with a physiologically acceptable carrier or excipient, which is active against Sarcoma 180.
摘要翻译：由我们指定为AX-2并由下式表示的物质：该物质通过培养链霉菌属的微生物并能够在培养基中产生AX-2并在培养的肉汤中积累AX-2而产生AX-2，从其中分离AX-2。一种抗肿瘤组合物，其包含与生理上可接受的载体或赋形剂相关联的有效量的AX-2，其对肉瘤180有活性。

3. 发明授权

US5344926A Process for producing staurosporine derivatives 失效
标题翻译：生产星形孢菌素衍生物的方法
公开(公告)号：US5344926A
公开(公告)日：1994-09-06
申请号：US79560
申请日：1993-06-22
申请人： Chikara Murakata , Toshimitsu Takiguchi , Shigeo Katsumata , Akira Mihara , Keiichi Takahashi , Hiromitsu Saito , Shiro Akinaga , Masami Okabe , Yutaka Saito
发明人： Chikara Murakata , Toshimitsu Takiguchi , Shigeo Katsumata , Akira Mihara , Keiichi Takahashi , Hiromitsu Saito , Shiro Akinaga , Masami Okabe , Yutaka Saito
IPC分类号： C07D498/22 , C07H9/06 , C07H19/04
CPC分类号： C07D498/22 , C07H19/04 , C07H9/06
摘要： Disclosed is a process for producing a staurosporine derivative represented by Formula (I): Q is defined as in specification: ##STR1## The staurosporine derivative (I-1) possesses selective protein kinase C-inhibitory and cell growth-inhibiting activities, and platelet-increasing activity.
摘要翻译：（I）星形孢菌素衍生物（I-1）具有选择性蛋白激酶C抑制和细胞生长抑制活性的方法，，血小板增多活性。

4. 发明授权

US4649199A Salt of DC-52 and a pharmaceutical composition containing the same 失效
标题翻译： DC-52的盐和含有它的药物组合物
公开(公告)号：US4649199A
公开(公告)日：1987-03-10
申请号：US697918
申请日：1985-02-04
申请人： Shinzo Ishii , Shigeo Katsumata , Yukou Arai , Kazuhisa Fujimoto , Makoto Morimoto
发明人： Shinzo Ishii , Shigeo Katsumata , Yukou Arai , Kazuhisa Fujimoto , Makoto Morimoto
IPC分类号： C07D498/22 , C12P17/18 , C12R1/465 , A61K31/495
CPC分类号： C07D498/22
摘要： A pharmacologically acceptable acid addition salt of DC-52 with 0.5-2.0 equivalent weight of inorganic acid, sulfonic acid, acidic amino acid, citric acid, transaconitic acid, .alpha.-ketoglutaric acid, itaconic acid, malonic acid or ascorbic acid on the basis of DC-52, having the same degree of antitumor activity as DC-52, is superior to DC-52 in stability at powdering or at preservation.
摘要翻译：磺酸，酸性氨基酸，柠檬酸，经官能度酸，α-酮戊二酸，衣康酸，丙二酸或抗坏血酸的基础上，加入0.5〜2.0当量的DC-52的药理学上可接受的酸加成盐与DC-52具有相同程度的抗肿瘤活性的DC-52在粉化或保存时的稳定性优于DC-52。

5. 发明授权

US06192660B1 Cap applying apparatus 有权
标题翻译：盖应用装置
公开(公告)号：US06192660B1
公开(公告)日：2001-02-27
申请号：US09230825
申请日：1999-06-03
申请人： Yasuyuki Moriyama , Elmar Mock , Michio Sugata , Shigeo Katsumata
发明人： Yasuyuki Moriyama , Elmar Mock , Michio Sugata , Shigeo Katsumata
IPC分类号： B65P5110
CPC分类号： B65B7/28
摘要： An apparatus for supplying and applying cap bodies (51) to a packaging container includes a gas supplying device (11) which supplies a hydrogen-oxygen gas mixture obtained by electrolyzing water, a burner unit (22) that is connected to the gas supplying device (11) for receiving hydrogen-oxygen gas mixture from the gas supplying device (11) and burning the hydrogen-oxygen gas mixture and a pickup apparatus (80) which transports a cap body (51) to a heating position above the burner unit (22). The burner unit (22) is provided with a plurality of nozzles (31) that are arranged in a pattern that corresponds in shape to the shape of the underside periphery of the cap body (51). A shield plate (57) is positionable above the nozzles (31) to deflect the hydrogen-oxygen gas mixture emitted from the nozzles (31), and an igniter (32) is disposed adjacent one of the nozzles (31), to ignite the mixture emitted from the nozzle (31). The other nozzles (31) are then ignited as the hydrogen-oxygen mixture from such nozzles (31) is deflected by the shield plate (57). A CCD camera (31) is also provided for monitoring the flame emitted from each of said nozzles (31).
摘要翻译：一种用于向包装容器供应和施加盖体（51）的装置包括：供给通过电解水获得的氢氧气体混合物的气体供给装置（11），与气体供给装置连接的燃烧器单元（22）（11），用于从气体供给装置（11）接收氢氧气体混合物并燃烧氢氧气体混合物;以及拾取装置（80），其将盖体（51）输送到燃烧器单元上方的加热位置（ 22）。燃烧器单元（22）设置有多个喷嘴（31），其以与盖体（51）的下侧周边的形状相对应的图案布置。屏蔽板（57）可定位在喷嘴（31）的上方，以偏转从喷嘴（31）排出的氢 - 氧气体混合物，点火器（32）邻近喷嘴（31）设置，以点燃从喷嘴（31）排出的混合物。然后，其他喷嘴（31）随着来自这些喷嘴（31）的氢氧混合物被屏蔽板（57）偏转而被点燃。还提供了一个CCD照相机（31），用于监测从每个所述喷嘴（31）发射的火焰。

6. 发明授权

US5366966A Compound UCE6 失效
标题翻译：化合物UCE6
公开(公告)号：US5366966A
公开(公告)日：1994-11-22
申请号：US070962
申请日：1993-06-04
申请人： Hirofumi Nakano , Noboru Fujii , Yoshinori Yamashita , Youichi Uosaki , Shigeru Chiba , Shigeo Katsumata , Yukari Tsuji
发明人： Hirofumi Nakano , Noboru Fujii , Yoshinori Yamashita , Youichi Uosaki , Shigeru Chiba , Shigeo Katsumata , Yukari Tsuji
IPC分类号： A61K31/12 , A61K31/122 , A61P35/00 , C07C50/38 , C12P15/00 , C12R1/01 , C07C15/38
CPC分类号： C12P15/00 , C07C50/38
摘要： A compound represented by formula (I): ##STR1## or a pharmaceutically acceptable salt thereof is provided, which has an excellent antitumor activity.
摘要翻译：提供由式（I）表示的化合物：其具有优异的抗肿瘤活性。

7. 发明授权

US4560661A Process for purifying enzymes 失效
标题翻译：纯化酶的方法
公开(公告)号：US4560661A
公开(公告)日：1985-12-24
申请号：US488174
申请日：1983-04-25
申请人： Hideo Katsumata , Shigeo Katsumata , Shinzo Ishii , Yuko Arai
发明人： Hideo Katsumata , Shigeo Katsumata , Shinzo Ishii , Yuko Arai
IPC分类号： C12N9/00 , C12N9/04 , C12N9/18 , C12N9/52 , C12N9/80 , C12N9/02 , C12N9/14 , C12N9/20 , C12N9/88 , C12N9/90 , C12N9/92
CPC分类号： C12N9/0006 , C12N9/00 , C12N9/18 , C12N9/52 , C12N9/80 , Y10S435/815
摘要： Disclosed is a process for purifying an enzyme contained in a solution such as cell extract liquor or fermentation culture liquor. The crude enzyme solution is brought into contact with either a strongly acidic cation exchange resin of high porous type or a strongly basic anion exchange resin of high porous type to adsorb the enzyme on the resin. An eluting agent is then passed through the resin to elute out the enzyme as a purified enzyme solution.
摘要翻译：公开了一种纯化细胞提取液或发酵培养液等溶液中所含的酶的方法。将粗酶溶液与高多孔型的强酸性阳离子交换树脂或高多孔型的强碱性阴离子交换树脂接触以将酶吸附在树脂上。然后将洗脱剂通过树脂以作为纯化酶溶液洗脱出酶。

8. 发明授权

US06370842B1 Wrapping material processor and process for manufacturing packing container 有权
标题翻译：包装材料处理器和制造包装容器的过程
公开(公告)号：US06370842B1
公开(公告)日：2002-04-16
申请号：US09463771
申请日：2000-02-01
申请人： Yasuyuki Moriyama , Yukihisa Kumeta , Shigeo Katsumata
发明人： Yasuyuki Moriyama , Yukihisa Kumeta , Shigeo Katsumata
IPC分类号： B65B6118
CPC分类号： B65B61/24 , B31B50/84 , B32B27/10 , B65B9/20 , B65B61/184 , B65D5/727
摘要： An object is to prevent roughening of a rupture surface of a packaging material (12) that is formed upon opening of a spout (21) through application of an external force. There are provided transport means for transporting a layered packaging material (12) that is formed of a paper substrate and resin films and that has a rupture area (52) at a location corresponding to that of opening means; a seal unit for sealing the packaging material (12); and heating means disposed on the upstream side of the seal unit in the transport direction of the packaging material (12) such that the heating means is opposed to an innermost layer of the packaging material (12) in order to heat the packaging material (12). In this case, after being heated and melted, the resin film of the packaging material (12) is gradually cooled. As a result, thermoplastic resin that constitutes the resin film is crystallized and becomes brittle. Accordingly, when an external force is applied by use of the opening means to thereby open the spout (21), the resin film does not stretch. As a result, the packaging material (12) can be easily ruptured, and the rupture surface of the packaging material (12) is prevented from being roughened, because the resin film does not have ruptured and stretched portions coexisting in a mixed manner.
摘要翻译：目的是防止通过施加外力而在喷口（21）打开时形成的包装材料（12）的破裂表面的粗糙化。提供了用于输送由纸基材和树脂膜形成的层状包装材料（12）的输送装置，并且在与打开装置相对应的位置具有破裂区域（52）; 密封单元，用于密封包装材料（12）; 以及在包装材料（12）的输送方向上设置在密封单元的上游侧的加热装置，使得加热装置与包装材料（12）的最内层相对，以加热包装材料（12））。在这种情况下，加热熔融后，包装材料（12）的树脂膜逐渐冷却。结果，构成树脂膜的热塑性树脂结晶化，变脆。因此，当通过使用打开装置施加外力从而打开出口（21）时，树脂膜不会伸展。结果，包装材料（12）可以容易地破裂，并且由于树脂膜没有破裂和拉伸部分以混合的方式共存，因此可以防止包装材料（12）的破裂表面变粗糙。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式