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1. 发明专利

JP2007186805A Deckle-edged japanese paper sheet for label and method for producing the same 审中-公开
标题翻译：用于标签的日文版日本纸张及其制造方法
公开(公告)号：JP2007186805A
公开(公告)日：2007-07-26
申请号：JP2006003686
申请日：2006-01-11
申请人： Tatsuhiro Ogawa , 達大小川
发明人： OGAWA TATSUHIRO
IPC分类号： D21F13/02 , D21F11/10
摘要： PROBLEM TO BE SOLVED: To provide deckle-edged Japanese paper sheets produced by hand-making or machine-making and aligned in longitudinal and lateral rows, a deckle-edged Japanese paper sheet for label to be printed in a state laminated to a releasing paper, and a method for producing the paper sheet.
SOLUTION: A plurality of deckle-edged Japanese paper sheets 7 produced by hand-making or machine-making in a state connected together by a thin line part 8 at regular intervals are dehydrated/dried and laminated to a releasing paper 12 to enable easy separation of the deckle-edged Japanese paper 7 in such a manner as to the cut-off of a postage stamp.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：为了提供通过手工制造或机械制造并且在纵向和横向排成对的板状日本纸张，用于标签的甲板边日本纸张被层压到脱模纸，以及纸张的制造方法。解决方案：通过在细线部8以规则间隔连接在一起的状态通过手工制造或机械制造而制造的多个平板日本纸张7脱水/干燥并层压到脱模纸12至能够容易地分离日志纸7，使得邮票被切断。版权所有（C）2007，JPO＆INPIT

2. 发明专利

JP2007031868A Paper for japanese paper label and method for producing the same 有权
标题翻译：日本纸张标签纸及其制造方法
公开(公告)号：JP2007031868A
公开(公告)日：2007-02-08
申请号：JP2005215174
申请日：2005-07-26
申请人： Tatsuhiro Ogawa , 達大小川
发明人： OGAWA TATSUHIRO
IPC分类号： D21H27/00 , B31D1/02 , D21F11/10 , G09F3/00
摘要： PROBLEM TO BE SOLVED: To provide paper for a Japanese paper label automatically applying each sheet of deckle edged Japanese paper to release paper and carrying out automatic printing and to provide a method for producing the paper.
SOLUTION: The production method comprises a step of draining/drying a plurality of sheets of deckle edged Japanese paper formed into the sheets by a machine and a step of successively applying the plurality of sheets of the dried deckle edged paper to the release paper.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：为了提供用于日本纸标签的纸张，自动地使用每张日志纸张以释放纸张并进行自动印刷并提供生产纸张的方法。解决方案：该生产方法包括通过机器排出/干燥形成片材的多张板状日本纸的步骤，以及将多张干燥的板状边缘纸张片连续地施加到释放的步骤纸。版权所有（C）2007，JPO＆INPIT

3. 发明授权

US06872803B1 Peptides 失效
标题翻译：多肽
公开(公告)号：US06872803B1
公开(公告)日：2005-03-29
申请号：US09349707
申请日：1999-07-08
申请人： Kenji Shibata , Toshiyuki Suzawa , Motoo Yamasaki , Koji Yamada , Tatsuhiro Ogawa , Takeo Tanaka , Shiro Soga
发明人： Kenji Shibata , Toshiyuki Suzawa , Motoo Yamasaki , Koji Yamada , Tatsuhiro Ogawa , Takeo Tanaka , Shiro Soga
IPC分类号： C07K14/58 , C07K14/745 , A61K38/10
CPC分类号： C07K14/745 , C07K14/58
摘要： The present invention provides peptides represented by the following formula (A): wherein Q represents a physiologically active peptide moiety; X each represents the same or different α-amino acid residue; M represents Gly or Cys; m represents an integer of from 5 to 8; and n represents an integer of from 0 to 3, or their pharmaceutically acceptable salts thereof. The peptides of the present invention have higher stability and/or higher activity than physiologically active linear peptides to which no cyclic peptide is bonded.
摘要翻译：本发明提供由下式（A）表示的肽：其中Q表示生理活性肽部分; X各自表示相同或不同的α-氨基酸残基; M表示Gly或Cys; m表示5〜8的整数，和n表示0〜3的整数，或其药学上可接受的盐。本发明的肽与没有结合肽的生理活性线性肽相比，具有更高的稳定性和/或更高的活性。

4. 发明授权

US06642355B2 Endothelin-antagonizing peptide 失效
标题翻译：内皮素拮抗肽
公开(公告)号：US06642355B2
公开(公告)日：2003-11-04
申请号：US09750754
申请日：2001-01-02
申请人： Takeo Tanaka , Yoshikazu Morishita , Mika Makino , Shigeru Chiba , Isao Kawamoto , Eiji Tsukuda , Mayumi Yoshida , Chieko Bando , Kazuo Yamaguchi , Yuzuru Matsuda , Shigeto Kitamura , Toshihide Ikemura , Tatsuhiro Ogawa , Keiichi Yano , Toshiyuki Suzawa , Kenji Shibata , Motoo Yamasaki
发明人： Takeo Tanaka , Yoshikazu Morishita , Mika Makino , Shigeru Chiba , Isao Kawamoto , Eiji Tsukuda , Mayumi Yoshida , Chieko Bando , Kazuo Yamaguchi , Yuzuru Matsuda , Shigeto Kitamura , Toshihide Ikemura , Tatsuhiro Ogawa , Keiichi Yano , Toshiyuki Suzawa , Kenji Shibata , Motoo Yamasaki
IPC分类号： C07K700
CPC分类号： C07K7/06 , A61K38/00 , C07K5/1021 , C07K5/1024 , C07K7/08 , C07K14/36 , C07K14/57536 , C12R1/465
摘要： The invention relates to an endothelin antagonistic peptide of the formula (I): X-A-Trp-B-Gly-Thr-E-G-Y (I) SEQ ID NO: 2 wherein represents Asn or Asp; B represents His or Lys; E represents Ala or Ser; G represents Ala or Pro; X represents X1-Gly or and Y represents hydroxy, lower alkoxy, amino, wherein X1, X3, Y1, Y2 and Z are further defined, or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明涉及式（I）的内皮素拮抗肽：其中代表Asn或Asp; B代表His或Lys; E表示Ala或Ser; G表示Ala或Pro; X表示X 1 -Gly或Y表示羟基，低级烷氧基，氨基，其中X 1，X 3，Y 1，Y 2和Z进一步定义，或其药学上可接受的盐。

5. 发明授权

US06194195B1 Strains of streptomyces producing endothelin antagonistic peptides 失效
标题翻译：产生内皮素拮抗肽的链霉菌菌株
公开(公告)号：US06194195B1
公开(公告)日：2001-02-27
申请号：US09181083
申请日：1998-10-27
申请人： Takeo Tanaka , Yoshikazu Morishita , Mika Makino , Shigeru Chiba , Isao Kawamoto , Eiji Tsukuda , Mayumi Yoshida , Chieko Bando , Kazuo Yamaguchi , Yuzuru Matsuda , Shigeto Kitamura , Toshihide Ikemura , Tatsuhiro Ogawa , Keiichi Yano , Toshiyuki Suzawa , Kenji Shibata , Motoo Yamasaki
发明人： Takeo Tanaka , Yoshikazu Morishita , Mika Makino , Shigeru Chiba , Isao Kawamoto , Eiji Tsukuda , Mayumi Yoshida , Chieko Bando , Kazuo Yamaguchi , Yuzuru Matsuda , Shigeto Kitamura , Toshihide Ikemura , Tatsuhiro Ogawa , Keiichi Yano , Toshiyuki Suzawa , Kenji Shibata , Motoo Yamasaki
IPC分类号： C12N120
CPC分类号： C07K7/06 , A61K38/00 , C07K5/1021 , C07K5/1024 , C07K7/08 , C07K14/36 , C07K14/57536 , C12R1/465
摘要： The invention relates to biologically pure cultures of Streptomyces sp. RE-701 (FERM BP-3624) and Streptomyces sp. RE-629 (FERM BP-4126) that produce endothelin antagonistic peptides.
摘要翻译：本发明涉及链霉菌属的生物纯培养物。 RE-701（FERM BP-3624）和Streptomyces sp。产生内皮素拮抗肽的RE-629（FERM BP-4126）。

6. 发明授权

US5639860A Endothelin-antagonizing peptide 失效
标题翻译：内皮素拮抗肽
公开(公告)号：US5639860A
公开(公告)日：1997-06-17
申请号：US321625
申请日：1994-10-12
申请人： Takeo Tanaka , Yoshikazu Morishita , Mika Makino , Shigeru Chiba , Isao Kawamoto , Eiji Tsukuda , Mayumi Yoshida , Chieko Bando , Kazuo Yamaguchi , Yuzuru Matsuda , Shigeto Kitamura , Toshihide Ikemura , Tatsuhiro Ogawa , Keiichi Yano , Toshiyuki Suzawa , Kenji Shibata , Motoo Yamasaki
发明人： Takeo Tanaka , Yoshikazu Morishita , Mika Makino , Shigeru Chiba , Isao Kawamoto , Eiji Tsukuda , Mayumi Yoshida , Chieko Bando , Kazuo Yamaguchi , Yuzuru Matsuda , Shigeto Kitamura , Toshihide Ikemura , Tatsuhiro Ogawa , Keiichi Yano , Toshiyuki Suzawa , Kenji Shibata , Motoo Yamasaki
IPC分类号： C07K5/113 , C07K5/117 , C07K7/06 , C07K7/08 , C07K14/575 , A61K38/10
CPC分类号： C07K7/06 , C07K14/57536 , C07K5/1021 , C07K5/1024 , C07K7/08
摘要： Peptides represented by the following formula (I): ##STR1## wherein A represents Asn or Asp; B represents His or Lys; and E represents Ala or Ser;(1) X.sup.1 and Y.sup.1 are combined together to form a single bond as X.sup.1 --Y1, or (2) X.sup.1 represents hydrogen and Y.sup.1 represents hydroxy;and Z represents, in case of (1),Trp-Phe-Phe-Asn-Tyr-Tyr-7Hyt-Z.sup.1Trp-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-Z.sup.1,Trp-Val-Tyr-Tyr-Ala-His-Leu-Asp-Ile-Ile-Trp-Z.sup.1,Trp-Leu-Tyr-Phe-Ala-His-Gln-Asp-Val-Ile-Trp-Z.sup.1,Trp-Phe-Phe-Asn-Tyr-R-T-Z.sup.1wherein Z.sup.1 is an organic moiety,wherein R is Tyr or a covalent bond,T is Trp, Ala, Phe, Tyr, Trp-Trp, Asn-Tyr-Tyr-Trp, Trp-Asn-Tyr-Tyr-Trp, Trp-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp,or in case of (2), Z representsTrp-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-Z.sup.1Trp-Val-Tyr-Tyr-Ala-His-Leu-Asp-Ile-Ile-Trp-Z.sup.1Trp-Leu-Tyr-Phe-Ala-His-Gln-Asp-Val-Ile-Trp-Z.sup.1.These peptides have endothelin-antagonizing activity, and are useful for treating hypertension, asthma, cerebral apoplexy, angina pectoris, acute renal failure, cardiac infarction and cerebral vasospasm.
摘要翻译：由下式（I）表示的肽：其中A表示Asn或Asp; B代表His或Lys; E表示Ala或Ser; （1）将X1和Y1组合在一起形成单键作为X1-Y1，或（2）X1表示氢，Y1表示羟基; 而在（1）的情况下，Z表示Trp-Phe-Phe-Asn-Tyr-Tyr-7Hyt-Z1 Trp-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-Z1， Trp-Val-Tyr-Tyr-Ala-His-Leu-Asp-Ile-Ile-Trp-Z1，Trp-Leu-Tyr-Phe-Ala-His-Gln-Asp-Val-Ile-Trp-Z1，Trp- Phe-Phe-Asn-Tyr-RT-Z1，其中Z1是有机部分，其中R是Tyr或共价键，T是Trp，Ala，Phe，Tyr，Trp-Trp，Asn-Tyr-Tyr-Trp，Trp -Tn-Tyr-Tyr-Trp，Trp-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp，或在（2）的情况下，Z表示Trp-Val-Tyr-Phe-Ala -His-Leu-Asp-Ile-Ile-Trp-Z1 Trp-Val-Tyr-Tyr-Ala-His-Leu-Asp-Ile-Ile-Trp-Z1 Trp-Leu-Tyr-Phe-Ala-His-Gln -Asp-Val-Ile-Trp-Z1。这些肽具有内皮素拮抗作用，可用于治疗高血压，哮喘，脑中风，心绞痛，急性肾功能衰竭，心肌梗死和脑血管痉挛。

7. 发明授权

US5138059A DC-89 compounds and process for their preparation 失效
标题翻译： DC-89化合物及其制备方法
公开(公告)号：US5138059A
公开(公告)日：1992-08-11
申请号：US380379
申请日：1989-07-17
申请人： Keiichi Takahashi , Michio Ichimura , Shigeo Katsumata , Tatsuhiro Ogawa , Makoto Morimoto , Tadashi Ashizawa , Masaji Kasai , Kenichi Muroi , Hiromitsu Saito , Hiroshi Sano , Toru Yasuzawa
发明人： Keiichi Takahashi , Michio Ichimura , Shigeo Katsumata , Tatsuhiro Ogawa , Makoto Morimoto , Tadashi Ashizawa , Masaji Kasai , Kenichi Muroi , Hiromitsu Saito , Hiroshi Sano , Toru Yasuzawa
IPC分类号： C12P17/18 , A61K31/40 , A61K31/435 , A61P31/04 , A61P35/00 , C07D471/04 , C07D487/04 , C12N1/20 , C12R1/465
CPC分类号： C07D471/04 , C07D487/04
摘要： Novel DC-89 compounds represented by the general formula: ##STR1## wherein X represents a single bond or --CH.sub.2 --; and when X represents a single bond, Y represents --CH.sub.2 Br or --CH.sub.2 Cl and when X represents --CH.sub.2 --, Y represents Br, are obtained by the present invention. The compounds have antibacterial and anti-tumor activity.

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