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1. 发明授权

US08729978B2 Quartz-crystal controlled oscillator 有权
标题翻译：石英晶振控制振荡器
公开(公告)号：US08729978B2
公开(公告)日：2014-05-20
申请号：US13562270
申请日：2012-07-30
申请人： Kazuo Akaike , Tsukasa Kobata , Tomoya Yorita , Kaoru Kobayashi
发明人： Kazuo Akaike , Tsukasa Kobata , Tomoya Yorita , Kaoru Kobayashi
IPC分类号： H03B5/36
CPC分类号： H03L1/022 , H03L1/028
摘要： An atmosphere temperature at which a quartz-crystal oscillator and an oscillation circuit are placed is controlled in high accuracy, and an output frequency with high stability is obtained. If oscillation outputs of first and second quartz-crystal oscillators are set to f1 and f2, and oscillation frequencies of the oscillation outputs at a reference temperature are set to f1r and f2r, respectively, {(f2−f1)/f1}−{(f2r−f1r)/f1r} is calculated by a frequency difference detection unit. A digital value can be obtained by representing this value by 34-bit digital value, corresponding to a temperature. Therefore, this value is treated as a temperature detection value, a difference with a temperature set value is supplied to the loop filter, and the digital value therefrom is converted into a direct-current voltage to control a heater.
摘要翻译：高精度地控制放置石英振荡器和振荡电路的气氛温度，并且获得具有高稳定性的输出频率。如果第一和第二石英晶体振荡器的振荡输出设定为f1和f2，并且将基准温度下的振荡输出的振荡频率分别设定为f1r和f2r，则{（f2-f1）/ f1} - {（ f2r-f1r）/ f1r}由频率差检测单元计算。通过对应于温度的34位数字值表示该值可以获得数字值。因此，将该值作为温度检测值，将与温度设定值的差被提供给环路滤波器，并将其数字值转换为直流电压以控制加热器。

2. 发明申请

US20120194277A1 OSCILLATION DEVICE 有权
标题翻译：振荡器件
公开(公告)号：US20120194277A1
公开(公告)日：2012-08-02
申请号：US13353942
申请日：2012-01-19
申请人： Kazuo AKAIKE , Kaoru Kobayashi
发明人： Kazuo AKAIKE , Kaoru Kobayashi
IPC分类号： H03L9/00
CPC分类号： H03L1/026 , H03L7/18
摘要： To perform, in an oscillation device compensating an output frequency based on a detection result of ambient temperature, temperature compensation of the output frequency with high accuracy. First and second quartz-crystal oscillators are structured by using a common quartz-crystal piece, and when oscillation outputs of first and second oscillation circuits respectively connected to these quartz-crystal oscillators are set to f1, f2, and oscillation frequencies of the first and the second oscillation circuits at a reference temperature are set to f1r, f2r, respectively, a frequency difference being a difference between a value corresponding to a difference between f1 and f1r and a value corresponding to a difference between f2 and f2r is treated as a temperature at that time. Further, based on the frequency difference, a frequency compensation value is determined through polynomial approximation.
摘要翻译：要在基于环境温度的检测结果对输出频率进行补偿的振荡装置中，以高精度进行输出频率的温度补偿。第一和第二石英晶体振荡器通过使用共同的石英晶体片构成，并且当分别连接到这些石英晶体振荡器的第一和第二振荡电路的振荡输出被设置为f1，f2，以及第一和第二晶体振荡器的振荡频率将参考温度下的第二振荡电路分别设定为f1r，f2r，将与f1和f1r之间的差值相对应的值与f2和f2r之间的差对应的频率差作为温度那时候。此外，基于频率差，通过多项式近似来确定频率补偿值。

3. 发明申请

US20120218048A1 OSCILLATION DEVICE 失效
标题翻译：振荡器件
公开(公告)号：US20120218048A1
公开(公告)日：2012-08-30
申请号：US13406694
申请日：2012-02-28
申请人： Kazuo Akaike , Kaoru Kobayashi
发明人： Kazuo Akaike , Kaoru Kobayashi
IPC分类号： H03L7/00
CPC分类号： H03L1/00
摘要： Provided is an oscillation device capable of obtaining a stable oscillation frequency by compensating for a change in oscillation frequency caused with an elapse of operating time of a quartz-crystal oscillator. A difference value ΔF between a frequency difference between first and second quartz-crystal oscillators after a predetermined period of time has elapsed from a reference time and a frequency difference between the first and second quartz-crystal oscillators at the reference time is determined.
摘要翻译：提供一种能够通过补偿由石英晶体振荡器的经过时间引起的振荡频率变化而获得稳定的振荡频率的振荡装置。确定从参考时间起经过了预定时间段之后的第一和第二石英晶体振荡器之间的频率差与基准时刻的第一和第二石英晶体振荡器之间的频率差的差值Dgr; F。

4. 发明授权

US08581670B2 Oscillation device 有权
标题翻译：振荡装置
公开(公告)号：US08581670B2
公开(公告)日：2013-11-12
申请号：US13353942
申请日：2012-01-19
申请人： Kazuo Akaike , Kaoru Kobayashi
发明人： Kazuo Akaike , Kaoru Kobayashi
IPC分类号： H03B5/36
CPC分类号： H03L1/026 , H03L7/18
摘要： To perform, in an oscillation device compensating an output frequency based on a detection result of ambient temperature, temperature compensation of the output frequency with high accuracy. First and second quartz-crystal oscillators are structured by using a common quartz-crystal piece, and when oscillation outputs of first and second oscillation circuits respectively connected to these quartz-crystal oscillators are set to f1, f2, and oscillation frequencies of the first and the second oscillation circuits at a reference temperature are set to f1r, f2r, respectively, a frequency difference being a difference between a value corresponding to a difference between f1 and f1r and a value corresponding to a difference between f2 and f2r is treated as a temperature at that time. Further, based on the frequency difference, a frequency compensation value is determined through polynomial approximation.
摘要翻译：要在基于环境温度的检测结果对输出频率进行补偿的振荡装置中，以高精度进行输出频率的温度补偿。第一和第二石英晶体振荡器通过使用共同的石英晶体片构成，并且当分别连接到这些石英晶体振荡器的第一和第二振荡电路的振荡输出被设置为f1，f2，以及第一和第二晶体振荡器的振荡频率将参考温度下的第二振荡电路分别设定为f1r，f2r，将与f1和f1r之间的差值相对应的值与f2和f2r之间的差对应的频率差作为温度那时候。此外，基于频率差，通过多项式近似来确定频率补偿值。

5. 发明授权

US08536952B2 Oscillation device 失效
标题翻译：振荡装置
公开(公告)号：US08536952B2
公开(公告)日：2013-09-17
申请号：US13406694
申请日：2012-02-28
申请人： Kazuo Akaike , Kaoru Kobayashi
发明人： Kazuo Akaike , Kaoru Kobayashi
IPC分类号： H03B5/32
CPC分类号： H03L1/00
摘要： Provided is an oscillation device capable of obtaining a stable oscillation frequency by compensating for a change in oscillation frequency caused with an elapse of operating time of a quartz-crystal oscillator. A difference value ΔF between a frequency difference between first and second quartz-crystal oscillators after a predetermined period of time has elapsed from a reference time and a frequency difference between the first and second quartz-crystal oscillators at the reference time is determined.
摘要翻译：提供一种能够通过补偿由石英晶体振荡器的经过时间引起的振荡频率变化而获得稳定的振荡频率的振荡装置。确定从参考时间起经过了预定时间段之后的第一和第二石英晶体振荡器之间的频率差和基准时刻的第一和第二石英晶体振荡器之间的频率差的差值ΔF。

6. 发明授权

US08228970B2 Signal processing device and wireless apparatus 有权
标题翻译：信号处理装置和无线装置
公开(公告)号：US08228970B2
公开(公告)日：2012-07-24
申请号：US12213881
申请日：2008-06-25
申请人： Kaoru Kobayashi , Shigeru Takegishi , Nobuo Tsukamoto
发明人： Kaoru Kobayashi , Shigeru Takegishi , Nobuo Tsukamoto
IPC分类号： H04B1/00
CPC分类号： H04B1/707
摘要： There is provided a signal processing device and a wireless apparatus capable of not erroneously determining polarity, appropriately performing a spread modulation process, a carrier modulation process, and reception data demodulation process, improving reception accuracy, and miniaturizing a circuit, even when IF carrier frequency shift occurs. The signal processing device and the wireless apparatus includes a spread modulation unit which includes a first differential encoding process section for performing a differential encoding process on a reception data, a differential encoding process section for performing a second differential encoding process on the output, and a spread modulation process section for performing a spread modulation process on the output using a spread code; a carrier modulation unit which quadrature-modulates a transmission data spread modulation signal and a continuous wave; and a reception data decoding unit which performs a correlation process twice and a delay detection process twice.
摘要翻译：提供了一种能够不错误地确定极性的信号处理装置和无线装置，适当地执行扩频调制处理，载波调制处理和接收数据解调处理，提高接收精度和使电路小型化，即使在IF载波频率班次发生。信号处理装置和无线装置包括扩展调制部，其包括对接收数据进行差分编码处理的第一差分编码处理部，对输出进行第二差分编码处理的差分编码处理部，扩展调制处理部分，用于使用扩展码对输出进行扩展调制处理; 载波调制单元，对发送数据扩展调制信号和连续波进行正交调制; 以及接收数据解码单元，其执行两次相关处理和延迟检测处理两次。

7. 发明授权

US08138335B2 Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient 有权
标题翻译：羧酸化合物和含有与活性成分相同的药物组合物
公开(公告)号：US08138335B2
公开(公告)日：2012-03-20
申请号：US12551860
申请日：2009-09-01
申请人： Atsushi Naganawa , Maki Iwahashi , Atsushi Kinoshita , Atsushi Shimabukuro , Seiji Ogawa , Koji Yano , Kaoru Kobayashi , Yutaka Okada , Yoko Kishida , Shouji Kawauchi , Kohki Tsukamoto , Yoko Matsunaga , Fumio Nambu
发明人： Atsushi Naganawa , Maki Iwahashi , Atsushi Kinoshita , Atsushi Shimabukuro , Seiji Ogawa , Koji Yano , Kaoru Kobayashi , Yutaka Okada , Yoko Kishida , Shouji Kawauchi , Kohki Tsukamoto , Yoko Matsunaga , Fumio Nambu
IPC分类号： C07D265/36 , A61K31/535
CPC分类号： C07D307/80 , A61K31/343 , A61K31/538 , C07D265/36 , C07D317/48
摘要： A compound represented by formula (I) wherein the symbols in the formula are the same meanings as those in specification, salts thereof, solvates thereof, or prodrugs thereof binds to DP receptor and shows antagonistic activity for DP receptor. Thus, it is useful for prevention and/or treatment of diseases such as allergic disease (e.g., allergic rhinitis, allergic conjunctivitis, atopic dermatitis, bronchial asthma and food allergy), systemic mastocytosis, disorders accompanied by systemic mast cell activation, anaphylaxis shock, bronchoconstriction, urticaria, eczema, diseases accompanied by itch (e.g., atopic dermatitis and urticaria), diseases (e.g., cataract, retinal detachment, inflammation, infection and sleeping disorders) which is generated secondarily as a result of behavior accompanied by itch (e.g., scratching and beating), inflammation, chronic obstructive pulmonary diseases, ischemic reperfusion injury, cerebrovascular accident, chronic rheumatoid arthritis, pleurisy, ulcerative colitis, etc. Since it specifically binds to DP receptor and binds weakly to other prostaglandins receptors, they can be pharmaceuticals having little side effect.
摘要翻译：由式（I）表示的化合物，其中式中的符号与说明书中的符号相同，其盐，溶剂合物或其前药与DP受体结合并显示DP受体的拮抗活性。因此，它可用于预防和/或治疗过敏性疾病（例如过敏性鼻炎，过敏性结膜炎，特应性皮炎，支气管哮喘和食物过敏），系统性肥大细胞增多症，伴有全身性肥大细胞活化的病症，过敏性休克，支气管收缩，荨麻疹，湿疹，伴有瘙痒的疾病（例如特应性皮炎和荨麻疹），伴随瘙痒的行为的结果产生的疾病（例如白内障，视网膜脱离，炎症，感染和睡眠障碍）（例如，搔抓和殴打），炎症，慢性阻塞性肺疾病，缺血再灌注损伤，脑血管意外，慢性类风湿关节炎，胸膜炎，溃疡性结肠炎等。由于其特异性结合DP受体并且弱结合到其他前列腺素受体，它们可以是具有小副作用。

8. 发明授权

US08026273B2 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient 失效
标题翻译： 8-氮杂的前列腺素衍生物化合物和包含该化合物作为活性成分的试剂
公开(公告)号：US08026273B2
公开(公告)日：2011-09-27
申请号：US12683609
申请日：2010-01-07
申请人： Kousuke Tani , Kaoru Kobayashi , Toru Maruyama , Tohru Kambe , Mikio Ogawa , Tsutomu Shiroya
发明人： Kousuke Tani , Kaoru Kobayashi , Toru Maruyama , Tohru Kambe , Mikio Ogawa , Tsutomu Shiroya
IPC分类号： A61K31/40 , A61K31/405 , C07D207/00 , C07D209/00
CPC分类号： C07D413/06 , C07D207/26 , C07D263/24 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/12 , C07D413/12 , C07D417/06 , C07D417/12
摘要： An 8-azaprostaglandin represented by formula (I) (wherein all symbols have the same meanings as described in the specification), a pharmaceutically acceptable salt thereof or a cyclodextrin clathrate thereof. Since the compound represented by formula (I) binds to EP2 subtype among PGE receptor strongly, it is useful for preventive and/or treatment for immune diseases, allergic diseases, neuronal cell death, dysmenorrhea, premature birth, abortion, baldness, retinal neuropathy such as glaucoma, erectile dysfunction, arthritis, pulmonary injury, pulmonary fibrosis, pulmonary emphysema, bronchitis, chronic obstructive pulmonary disease, hepatic injury, acute hepatitis, liver cirrhosis, shock, nephritis, renal failure, circulatory diseases, systemic inflammatory response syndrome, sepsis, hemophagocytosis syndrome, macrophage activation syndrome, still disease, Kawasaki Disease, burn, systemic granuloma, ulcerative colitis, Crohn disease, hypercytokinemia at dialysis, multiple organ failure, or bone diseases etc.
摘要翻译：由式（I）（其中所有符号具有与说明书中所述相同的含义）表示的8-氮杂前列腺素，其药学上可接受的盐或其环糊精包合物。由于式（I）表示的化合物强烈地与PGE受体中的EP2亚型结合，因此可用于免疫疾病，过敏性疾病，神经元细胞死亡，痛经，早产，流产，秃发，视网膜神经病变等的预防和/或治疗青光眼，勃起功能障碍，关节炎，肺损伤，肺纤维化，肺气肿，支气管炎，慢性阻塞性肺病，肝损伤，急性肝炎，肝硬化，休克，肾炎，肾衰竭，循环系统疾病，全身性炎症反应综合征，败血症，血细胞增多综合征，巨噬细胞活化综合征，静止病，川崎病，烧伤，全身肉芽肿，溃疡性结肠炎，克罗恩病，透析中的高细胞因子血症，多器官功能衰竭或骨骼疾病等。

9. 发明申请

US20100010222A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DISEASES ASSOCIATED WITH DECREASE IN BONE MASS COMPRISING EP4 AGONIST AS ACTIVE INGREDIENT 有权
标题翻译：用于治疗与包含EP4激动剂作为主动成分的骨质疏松相关的疾病的药物组合物
公开(公告)号：US20100010222A1
公开(公告)日：2010-01-14
申请号：US12549136
申请日：2009-08-27
申请人： Toru MARUYAMA , Kaoru Kobayashi , Tohru Kambe , Takayuki Maruyama , Hideyuki Yoshida , Akio Nishiura , Nobutaka Abe
发明人： Toru MARUYAMA , Kaoru Kobayashi , Tohru Kambe , Takayuki Maruyama , Hideyuki Yoshida , Akio Nishiura , Nobutaka Abe
IPC分类号： C07D241/04 , C07C405/00 , C07D207/12 , C07D401/12
CPC分类号： C07C405/0033 , A61K9/0019 , A61K9/1647 , A61K9/19 , A61K9/2054 , A61K31/4015 , A61K31/41 , A61K31/5575 , A61K31/559
摘要： A pharmaceutical composition for topical administration for prevention and/or treatment of diseases associated with decrease in bone mass comprising an EP4 agonist as an active ingredient. An EP4 agonist, in which includes a compound possessing prostaglandin skeleton as a representative, possesses promoting action on bone formation, so it is useful for prevention and/or treatment of diseases associated with decrease in bone mass (bone diseases such as primary osteoporosis, secondary osteoporosis, bone metastasis of cancer, hypercalcemia, Paget's disease, bone loss and bone necrosis, postoperative osteogenesis, alternative therapy for bone grafting).
摘要翻译：用于预防和/或治疗与包含EP4激动剂作为活性成分的骨量减少相关的疾病的局部施用的药物组合物。包含具有前列腺素骨架的化合物作为代表的EP4激动剂具有促进骨形成的作用，因此可用于预防和/或治疗与骨质量减少有关的疾病（骨疾病如原发性骨质疏松症，继发性骨质疏松症骨质疏松症，癌症的骨转移，高钙血症，佩吉特氏病，骨丢失和骨坏死，术后成骨，骨移植的替代疗法）。

10. 发明申请

US20090279646A1 Wireless communication device 审中-公开
标题翻译：无线通信设备
公开(公告)号：US20090279646A1
公开(公告)日：2009-11-12
申请号：US12458678
申请日：2009-07-20
申请人： Kaoru Kobayashi , Shigeru Takegishi
发明人： Kaoru Kobayashi , Shigeru Takegishi
IPC分类号： H04L27/06
CPC分类号： H04L27/0014 , H04B1/70752
摘要： A wireless communication device is provided to carry out correlation peak detection processing properly and efficiently in intermittent receiving unit. If a correlation peak is not detected in a first period in which a correlation peak detecting unit detects the correlation peak at a default frequency and a first frequency in a detecting period of a coarse frequency deviation detecting unit in the first period, a control unit makes the correlation peak detecting unit carry out the peak detection at the first frequency in a second period. If the correlation peak is detected in the correlation peak detecting unit and a second frequency is detected in a detecting period of a fine frequency deviation detecting unit in the first period, the control unit makes the correlation peak detecting unit carry out the peak detection at the first and second frequencies in a third period.
摘要翻译：提供一种无线通信装置，用于在间歇接收单元中适当且有效地执行相关峰值检测处理。如果在第一期间中相关峰值检测部检测到粗略频率偏差检测部的检测期间的默认频率的相关峰值和第一频率的第一期间没有检测到相关峰值，则控制部相关峰值检测单元在第二周期中以第一频率执行峰值检测。如果在相关峰值检测单元中检测到相关峰值，并且在第一周期内在精细频率偏差检测单元的检测周期中检测到第二频率，则控制单元使相关峰值检测单元在第一和第二频率在第三个时期。

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