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1. 发明授权

US08993536B2 Low-molecular polysulfated hyaluronic acid derivative and medicine containing same 有权
标题翻译：低分子多硫酸化透明质酸衍生物及其含有药物
公开(公告)号：US08993536B2
公开(公告)日：2015-03-31
申请号：US13143129
申请日：2010-02-01
申请人： Kazuaki Kakehi , Hiroaki Asai , Naohiro Hayashi , Satoshi Shimizu , Fumitaka Goto , Yasuo Koga , Takahiro Tomoyasu , Takao Taki , Yusuke Kato , Satoru Nakazato , Junji Takaba , Atsushi Azuma , Wakako Hirano , Kazunari Izumi , Minoru Kashimoto , Yoko Sakamoto , Takashi Hayashi , Masaru Nishida
发明人： Kazuaki Kakehi , Hiroaki Asai , Naohiro Hayashi , Satoshi Shimizu , Fumitaka Goto , Yasuo Koga , Takahiro Tomoyasu , Takao Taki , Yusuke Kato , Satoru Nakazato , Junji Takaba , Atsushi Azuma , Wakako Hirano , Kazunari Izumi , Minoru Kashimoto , Yoko Sakamoto , Takashi Hayashi , Masaru Nishida
IPC分类号： A61K31/728 , A61P11/06 , A61P17/00 , A61P37/08 , C08B37/08
CPC分类号： A61K31/728 , C08B37/0072
摘要： A low-molecular-weight polysulfated hyaluronic acid derivative useful for treatment of an allergic disease. An agent for treatment of an allergic disease selected from pollinosis, allergic rhinitis, allergic conjunctivitis, atopic dermatitis, and asthma, represented by the following general formula (IA) or (IB); wherein n represents a number of 0 to 15; R's each independently represent a hydrogen atom or an SO3H group etc.
摘要翻译：用于治疗过敏性疾病的低分子量多硫酸化透明质酸衍生物。用于治疗选自以下通式（IA）或（IB）表示的花粉病，过敏性鼻炎，过敏性结膜炎，特应性皮炎和哮喘的过敏性疾病的药剂; 其中n表示0〜15的数; R各自独立地表示氢原子或SO 3 H基等

2. 发明申请

US20110281819A1 LOW-MOLECULAR POLYSULFATED HYALURONIC ACID DERIVATIVE AND MEDICINE CONTAINING SAME 有权
标题翻译：低分子量聚羟基丙酸衍生物和含有其的药物
公开(公告)号：US20110281819A1
公开(公告)日：2011-11-17
申请号：US13143129
申请日：2010-02-01
申请人： Kazuaki Kakehi , Hiroaki Asai , Naohiro Hayashi , Satoshi Shimizu , Fumitaka Goto , Yasuo Koga , Takahiro Tomoyasu , Takao Taki , Yusuke Kato , Satoru Nakazato , Junji Takaba , Atsushi Azuma , Wakako Hirano , Kazunari Izumi , Minoru Kashimoto , Yoko Sakamoto , Takashi Hayashi , Masaru Nishida
发明人： Kazuaki Kakehi , Hiroaki Asai , Naohiro Hayashi , Satoshi Shimizu , Fumitaka Goto , Yasuo Koga , Takahiro Tomoyasu , Takao Taki , Yusuke Kato , Satoru Nakazato , Junji Takaba , Atsushi Azuma , Wakako Hirano , Kazunari Izumi , Minoru Kashimoto , Yoko Sakamoto , Takashi Hayashi , Masaru Nishida
IPC分类号： A61K31/728 , A61P11/06 , A61P17/00 , C08B37/08 , A61P37/08
CPC分类号： A61K31/728 , C08B37/0072
摘要： A low-molecular-weight polysulfated hyaluronic acid derivative useful for prevention and/or treatment of an allergic disease. An agent for prevention and/or treatment of an allergic disease selected from pollinosis, allergic rhinitis, allergic conjunctivitis, atopic dermatitis, and asthma, represented by the following general formula (IA) or (IB); wherein n represents a number of 0 to 15; R′s each independently represent a hydrogen atom or an SO3H group etc.
摘要翻译：用于预防和/或治疗过敏性疾病的低分子量多硫酸化透明质酸衍生物。由以下通式（IA）或（IB）表示的预防和/或治疗选自传粉炎，过敏性鼻炎，过敏性结膜炎，特应性皮炎和哮喘的过敏性疾病的药剂; 其中n表示0〜15的数; R各自独立地表示氢原子或SO 3 H基等

3. 发明授权

US07287500B2 Start controller for internal combustion engine 有权
标题翻译：内燃机启动控制器
公开(公告)号：US07287500B2
公开(公告)日：2007-10-30
申请号：US11273326
申请日：2005-11-15
申请人： Kazunari Izumi , Haruyuki Urushihata
发明人： Kazunari Izumi , Haruyuki Urushihata
IPC分类号： F02D41/06
CPC分类号： F02D13/0226 , F02D41/0002 , F02D41/062 , F02D2013/0292 , F02D2041/001 , F02N11/08 , Y02T10/18 , Y02T10/42
摘要： At an intake timing of an initial combustion cylinder, an actual intake valve timing is adjusted to a target intake valve timing corresponding to a target intake air flow rate of the initial combustion cylinder. At intake timing of the other cylinders which contributes to increment of the engine speed after the initial combustion, the actual intake valve timing is adjusted to a target valve timing corresponding to a target intake air flow rate of the other cylinders. Thereby, the intake air flow rate of each cylinder is accurately controlled, so that the increment of the engine speed is restricted within a range in which a startability is not deteriorated and a vehicle vibration and an over shoot of the engine speed is appropriately restricted.
摘要翻译：在初始燃烧气缸的进气正时，将实际进气门正时调整为与初始燃烧气缸的目标进气流量对应的目标进气门正时。在有助于初始燃烧后的发动机转速增加的其他气缸的进气时刻，将实际进气门正时调整为与其他气缸的目标进气流量对应的目标气门正时。因此，精确地控制各气缸的进气流量，从而将发动机转速的增加限制在不劣化起动性的范围内，适当地限制发动机转速的车辆振动和过冲。

4. 发明申请

US20060042579A1 Variable valve timing controller for internal combustion engine 有权
标题翻译：内燃机可变气门正时控制器
公开(公告)号：US20060042579A1
公开(公告)日：2006-03-02
申请号：US11213900
申请日：2005-08-30
申请人： Kazunari Izumi , Haruyuki Urushihata
发明人： Kazunari Izumi , Haruyuki Urushihata
IPC分类号： F01L1/34
CPC分类号： F01L1/352 , F01L1/022 , F01L1/024 , F01L1/34 , F01L2820/032 , F01L2820/041
摘要： A variable valve timing controller adjusts valve timing of an intake valve and/or an exhaust valve by varying a motor speed relative to a camshaft. When an engine is running under a predetermined condition, an actual valve timing is calculated based on a cam angle signal and crank angle signal every when the cam angle signal is inputted. A final valve timing is calculated by adding a valve timing variation amount to the actual valve timing at the time the cam angle signal is outputted. The valve timing amount is periodically calculated based on a difference between a motor speed and a rotational speed of the intake camshaft. When the engine is running under another condition, only actual valve timing at the time the cam angle signal is outputted is calculated.
摘要翻译：可变气门正时控制器通过改变相对于凸轮轴的电动机转速来调节进气门和/或排气门的气门正时。当发动机在预定条件下运行时，每当输入凸轮角信号时，基于凸轮角信号和曲柄角信号计算实际气门正时。通过在输出凸轮角信号时将气门正时变化量与实际气门正时相加来计算最终气门正时。基于电动机速度和进气凸轮轴的转速之间的差异周期性地计算气门正时量。当发动机在另一条件下运行时，仅计算在输出凸轮角信号时的实际气门正时。

5. 发明申请

US20100140001A1 HYBRID VEHICLE 有权
标题翻译：混合动力车
公开(公告)号：US20100140001A1
公开(公告)日：2010-06-10
申请号：US12450804
申请日：2008-05-15
申请人： Yu Oe , Kazunari Izumi
发明人： Yu Oe , Kazunari Izumi
IPC分类号： B60W10/04 , B60W20/00
CPC分类号： B60W20/10 , B60K1/02 , B60K6/26 , B60K6/365 , B60K6/445 , B60K2001/0416 , B60L2240/441 , B60W10/06 , B60W10/08 , B60W10/30 , B60W20/00 , B60W2510/0638 , B60W2520/10 , B60W2530/14 , B60W2540/10 , B60W2720/10 , F02B1/04 , F02D29/02 , F02M25/089 , F02M37/007 , Y02T10/6239 , Y02T10/6286
摘要： A hybrid vehicle includes a fuel tank (180) for storing fuel (FL) for an engine (2), a circulation system (a pump (186), a first path (187), a pressure regulator (130), and a second path (184)) for circulating the fuel (FL), and a control device (hybrid control unit (62)). When the hybrid vehicle is in a vehicular state that satisfies a predetermined condition, the control device controls the hybrid vehicle so that it performs EV traveling (electrical vehicle traveling) in which wheels are driven by a rotating electrical machine with the engine (2) stopped. When the stop period of the engine (2) is equal to or longer than a predetermined period, the control device drives the circulation system to circulate the fuel (FL).
摘要翻译：混合动力车辆包括用于存储用于发动机（2）的燃料（FL）的燃料箱（180），循环系统（泵（186）），第一路径（187），压力调节器（130）和第二路径（184）），以及控制装置（混合控制单元（62））。当混合动力车辆处于满足预定条件的车辆状态时，控制装置控制混合动力车辆，使得执行EV行驶（电动车辆行驶），其中发动机（2）停止的旋转电机驱动车轮。当发动机（2）的停止期间等于或大于预定时间时，控制装置驱动循环系统使燃料（FL）循环。

6. 发明授权

US08275503B2 Vehicle and control method of vehicle 有权
标题翻译：车辆的车辆和控制方法
公开(公告)号：US08275503B2
公开(公告)日：2012-09-25
申请号：US12615053
申请日：2009-11-09
申请人： Kazunari Izumi
发明人： Kazunari Izumi
IPC分类号： B60T8/00
CPC分类号： B60W10/184 , B60W10/08 , B60W30/18118 , B60W2550/142
摘要： A vehicle includes: an electric motor that outputs power to a drive shaft that is coupled to a first wheel, which is a primary drive wheel; an electrical storage device that exchanges electrical power with the electric motor; a braking system that can independently apply a braking force to the first wheel and a second wheel that is a free rolling wheel or a drive wheel other than the first wheel, regardless of a braking request by a driver; and a control unit that controls the braking system and the electric motor such that the braking system applies the braking force only to the second wheel and that output torque of the electric motor becomes equal to or lower than specified torque until rotational speed of the electric motor reach specified revolution when a start-up request is made by the driver while the vehicle is at a halt on a driving road surface whose inclination, which is acquired by an inclination acquisition device, is larger than or equal to specified inclination. The present invention also relates to a control method of the vehicle.
摘要翻译：车辆包括：电动机，其向耦合到作为主驱动轮的第一车轮的驱动轴输出动力; 与电动机交换电力的蓄电装置; 制动系统，其可以独立地对第一车轮施加制动力，第二车轮是作为自由滚轮或不同于第一车轮的驱动轮，而不管驾驶员的制动要求如何; 以及控制单元，其控制制动系统和电动机，使得制动系统仅将制动力施加到第二轮，并且电动机的输出转矩等于或低于规定的转矩直到电动机的转速当车辆在由倾斜获取装置获取的倾斜度大于或等于指定倾斜度的行驶路面上停止时驾驶员进行起动请求时达到规定的转速。本发明还涉及车辆的控制方法。

7. 发明授权

US07178494B2 Variable valve timing controller for internal combustion engine 失效
标题翻译：内燃机可变气门正时控制器
公开(公告)号：US07178494B2
公开(公告)日：2007-02-20
申请号：US11248251
申请日：2005-10-13
申请人： Kazunari Izumi , Haruyuki Urushihata
发明人： Kazunari Izumi , Haruyuki Urushihata
IPC分类号： F01L1/34 , F02D13/04
CPC分类号： F02D13/0219 , F01L1/344 , F01L2800/00 , F01L2800/14 , F01L2820/041 , F01L2820/042 , F02D41/009 , F02D41/0097 , F02D2041/001 , Y02T10/18
摘要： An ECU calculates an engine speed for calculating a camshaft phase based on a time period Tθ in which a crankshaft rotates a sampling angle θ. The camshaft phase is derived from a time difference between output timing of a cam angle signal and output timing of a crank angle signal based on the engine speed. According as the engine speed is lower, the sampling angle θ becomes small, so that the engine speed and the camshaft phase are precisely calculated.
摘要翻译： ECU基于曲轴旋转采样角度θ的时间段Tta来计算用于计算凸轮轴相位的发动机转速。凸轮轴相位是根据发动机转速从凸轮角度信号的输出定时和曲柄角信号的输出定时之间的时间差导出的。根据发动机转速较低，采样角度θ变小，从而精确计算发动机转速和凸轮轴相位。

8. 发明授权

US08645049B2 Control device for vehicle 有权
标题翻译：车辆控制装置
公开(公告)号：US08645049B2
公开(公告)日：2014-02-04
申请号：US12862035
申请日：2010-08-24
申请人： Kazunari Izumi
发明人： Kazunari Izumi
IPC分类号： F02N11/08 , B60W20/00 , B60W10/20
CPC分类号： B60W30/18018 , B60K6/48 , B60L2240/421 , B60L2240/441 , B60W10/06 , B60W10/08 , B60W20/00 , B60W2510/0638 , B60W2510/081 , B60W2510/244 , F02D17/04 , F02D29/02 , F02N11/0866 , F02N2011/0888 , F02N2011/0896 , Y02T10/48 , Y02T10/6221 , Y02T10/6286 , Y02T10/642
摘要： A motor generator is connected to a high voltage battery through an inverter. A voltage of the high voltage battery is decreased and is applied to a low voltage battery through a DC-DC converter. At time of starting an engine, a starting operation of a starter is executed by applying an output voltage of the DC-DC converter 36 to the starter. At this time, the output voltage of the DC-DC converter 36 may be adjusted based on the temperature of the engine, the voltage of the low voltage battery and/or the degree of degradation of lubricant oil of the engine.
摘要翻译：电动发电机通过变频器与高电压电池连接。高电压电池的电压降低，并通过DC-DC转换器施加到低电压电池。在启动发动机时，通过将DC-DC转换器36的输出电压施加到起动器来执行起动器的起动操作。此时，可以基于发动机的温度，低压电池的电压和/或发动机的润滑油的劣化程度来调节DC-DC转换器36的输出电压。

9. 发明授权

US08220573B2 Hybrid vehicle 有权
标题翻译：混合动力汽车
公开(公告)号：US08220573B2
公开(公告)日：2012-07-17
申请号：US12450804
申请日：2008-05-15
申请人： Yu Oe , Kazunari Izumi
发明人： Yu Oe , Kazunari Izumi
IPC分类号： B60W20/00
CPC分类号： B60W20/10 , B60K1/02 , B60K6/26 , B60K6/365 , B60K6/445 , B60K2001/0416 , B60L2240/441 , B60W10/06 , B60W10/08 , B60W10/30 , B60W20/00 , B60W2510/0638 , B60W2520/10 , B60W2530/14 , B60W2540/10 , B60W2720/10 , F02B1/04 , F02D29/02 , F02M25/089 , F02M37/007 , Y02T10/6239 , Y02T10/6286
摘要： A hybrid vehicle includes a fuel tank for storing fuel for an engine, a circulation system (a pump), a first path, a pressure regulator, and a second path for circulating the fuel, and a control device (hybrid control unit). When the hybrid vehicle is in a vehicular state that satisfies a predetermined condition, the control device controls the hybrid vehicle so that it performs EV traveling (electrical vehicle traveling) in which wheels are driven by a rotating electrical machine with the engine stopped. When the stop period of the engine is equal to or longer than a predetermined period, the control device drives the circulation system to circulate the fuel.
摘要翻译：混合动力车辆包括用于存储用于发动机的燃料的燃料箱，循环系统（泵），第一路径，压力调节器和用于使燃料循环的第二路径，以及控制装置（混合动力控制单元）。当混合动力车辆处于满足预定条件的车辆状态时，控制装置控制混合动力车辆，使得在发动机停止的情况下，通过旋转电机来执行车轮驱动的EV行驶（电动汽车行驶）。当发动机的停止时间等于或大于预定时间时，控制装置驱动循环系统使燃料循环。

10. 发明授权

US07661403B2 Start controller for internal combustion engine 有权
标题翻译：内燃机启动控制器
公开(公告)号：US07661403B2
公开(公告)日：2010-02-16
申请号：US11822486
申请日：2007-07-06
申请人： Kazunari Izumi
发明人： Kazunari Izumi
IPC分类号： F02N17/00
CPC分类号： F02D13/0226 , F02D41/0002 , F02D41/062 , F02D2013/0292 , F02D2041/001 , F02N11/08 , Y02T10/18 , Y02T10/42
摘要： At an intake timing of an initial combustion cylinder, an actual intake valve timing is adjusted to a target intake valve timing corresponding to a target intake air flow rate of the initial combustion cylinder. At intake timing of the other cylinders which contributes to increment of the engine speed after the initial combustion, the actual intake valve timing is adjusted to a target valve timing corresponding to a target intake air flow rate of the other cylinders. Thereby, the intake air flow rate of each cylinder is accurately controlled, so that the increment of the engine speed is restricted within a range in which a startability is not deteriorated and a vehicle vibration and an over shoot of the engine speed is appropriately restricted.
摘要翻译：在初始燃烧气缸的进气正时，将实际进气门正时调整为与初始燃烧气缸的目标进气流量对应的目标进气门正时。在有助于初始燃烧后的发动机转速增加的其他气缸的进气时刻，将实际进气门正时调整为与其他气缸的目标进气流量对应的目标气门正时。因此，精确地控制各气缸的进气流量，从而将发动机转速的增加限制在不劣化起动性的范围内，适当地限制发动机转速的车辆振动和过冲。

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