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    • 1. 发明申请
    • Biochip and biochip kit, and method of producing the same and method of using the same
    • 生物芯片和生物芯片试剂盒及其制备方法及其使用方法
    • US20060252044A1
    • 2006-11-09
    • US10554218
    • 2004-04-23
    • Katsuya OkumuraMakoto MiharaMutsuhiko Yoshioka
    • Katsuya OkumuraMakoto MiharaMutsuhiko Yoshioka
    • C12Q1/68C12M1/34H01L21/00
    • B01L3/50255B01L2300/0681B01L2300/0819G01N33/54373
    • There are provided a biochip and a biochip kit, in which a target contained in an analyte is reacted with a probe with high efficiency in a short time, B/F separation efficiency is high, and high-sensitive quantitative determination and detection can be realized, and a production process thereof, and a method for reacting a target contained in an analyte with a probe, and, for example, separation and fractionation method and a detection and identification method for a target contained in an analyte, using the biochip kit. The biochip according to the present invention comprises a well(s) provided with a filter comprising straight pores, with a uniform pore diameter, provided at uniform pore spacings. A dispersion with probe-supported particles dispersed therein is contained in the well, and an analyte is placed in the well(s) to react the analyte with the probe-supported particles. A solution such as an analyte solution can be introduced into or discharged from the well through the filter.
    • 提供了生物芯片和生物芯片试剂盒,其中包含在分析物中的靶在短时间内与探针高效率地反应,B / F分离效率高,并且可以实现高灵敏度的定量测定和检测 及其制备方法,以及使用生物芯片试剂盒使包含在分析物中的靶与探针反应的方法,例如分离和分级方法以及包含在分析物中的靶的检测和鉴定方法。 根据本发明的生物芯片包括设置有均匀孔隙的具有均匀孔径的直孔的过滤器,孔设置成均匀的孔隙。 将分散在其中的探针负载颗粒的分散体包含在孔中,并将分析物放置在孔中以使分析物与探针负载的颗粒反应。 诸如分析物溶液的溶液可以通过过滤器引入或从井中排出。