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1. 发明授权

US07416596B2 Use of a pigment composition comprising mixed crystals based on CI pigment yellow 74 有权
标题翻译：使用包含基于CI颜料黄74的混合晶体的颜料组合物
公开(公告)号：US07416596B2
公开(公告)日：2008-08-26
申请号：US10590828
申请日：2005-02-11
申请人： Karl-Heinz Schweikart , David Blum , Felix W. Grimm , Martin U. Schmidt , Josef Geisenberger
发明人： Karl-Heinz Schweikart , David Blum , Felix W. Grimm , Martin U. Schmidt , Josef Geisenberger
IPC分类号： C09D11/00 , C09D11/02 , C09B67/22 , G02B5/20
CPC分类号： C09D11/32 , C09D11/101 , C09D11/322 , C09D11/34
摘要： The invention relates to the use of a pigment composition containing between 86.0 and 99.9 total mol % of C.I. Pigment Yellow 74 molecules and between 14.0 and 0.1 total mol % of at least one monoazo pigment of the formula (1) wherein R1 represents Cl, OCH3, OH3 or NO2 as a coloring agent for pigmenting ink-jet inks and color filters.
摘要翻译：本发明涉及使用含有86.0-99.9％总摩尔％的C.I.的颜料组合物。颜料黄74分子和14.0至0.1总摩尔％的至少一种式（1）的单偶氮颜料，其中R 1表示Cl，OCH 3，OH， > 3或NO 2 2作为用于着色喷墨油墨和滤色器的着色剂。

2. 发明申请

US20070169665A1 Use of a pigment composition comprising mixed crystals based on ci pigment yellow 74 有权
标题翻译：使用包含基于ci颜料黄色的混合晶体的颜料组合物74
公开(公告)号：US20070169665A1
公开(公告)日：2007-07-26
申请号：US10590828
申请日：2005-02-11
申请人： Karl-Heinz Schweikart , David Blum , Felix Grimm , Martin Schmidt , Josef Geisenberger
发明人： Karl-Heinz Schweikart , David Blum , Felix Grimm , Martin Schmidt , Josef Geisenberger
IPC分类号： G03F1/00 , C09B27/00 , C09D11/00
CPC分类号： C09D11/32 , C09D11/101 , C09D11/322 , C09D11/34
摘要： The invention relates to the use of a pigment composition containing between 86.0 and 99.9 total mol % of C.I. Pigment Yellow 74 molecules and between 14.0 and 0.1 total mol % of at least one monoazo pigment of the formula (1) wherein R1 represents Cl, OCH3, CH3 or NO2 as a colouring agent for pigmenting ink-jet inks and colour filters.
摘要翻译：本发明涉及使用含有86.0-99.9％总摩尔％的C.I.的颜料组合物。颜料黄74分子和14.0至0.1总摩尔％的至少一种式（1）的单偶氮颜料，其中R 1表示Cl，OCH 3，CH _{3或NO 2 2作为用于着色喷墨油墨和滤色器的着色剂。}

3. 发明授权

US08426184B2 Cellulases, nucleic acids encoding them and methods for making and using them 有权
标题翻译：纤维素酶，编码它们的核酸和制备和使用它们的方法
公开(公告)号：US08426184B2
公开(公告)日：2013-04-23
申请号：US11908672
申请日：2006-01-13
申请人： David Blum , Joslin Gemsch Cuenca , Mark Dycaico
发明人： David Blum , Joslin Gemsch Cuenca , Mark Dycaico
IPC分类号： C12N9/42 , C12N9/14 , C12N15/00 , C12N1/20 , C12P21/06 , C12P19/00 , C12P7/06 , A62D3/00 , C07H21/04 , A61K38/47 , A23C17/00 , A01H5/00
CPC分类号： C12N9/2437 , C10L1/02 , C10L1/023 , C10L2200/0423 , C10L2200/0469 , C10L2290/26 , C12P7/10 , C12Y302/01004 , C12Y302/01091 , Y02E50/16 , Y02E50/17
摘要： This invention relates to molecular and cellular biology and biochemistry. In one aspect, the invention provides polypeptides having cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or β-glucosidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or β-glucosidase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts.
摘要翻译：本发明涉及分子和细胞生物学和生物化学。一方面，本发明提供了具有纤维素酶活性的多肽，例如内切葡聚糖酶，纤维二糖水解酶，甘露聚糖酶和/或β-葡糖苷酶活性，编码这些多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。一方面，本发明涉及多肽纤维素酶活性，例如内切葡聚糖酶，纤维二糖水解酶，甘露聚糖酶和/或β-葡糖苷酶活性，包括耐热和耐热活性，以及编码这些酶的多核苷酸，以及制备和使用这些多核苷酸和多肽。本发明的多肽可用于各种药物，农业，食品和饲料加工以及工业环境中。

4. 发明申请

US20100003234A1 Cellulases, Nucleic Acids Encoding Them and Methods for Making and Using Them 有权
标题翻译：纤维素酶，编码它们的核酸及其制备和使用方法
公开(公告)号：US20100003234A1
公开(公告)日：2010-01-07
申请号：US11908672
申请日：2006-01-13
申请人： David Blum , Joslin Gemsch , Mark Dycaico
发明人： David Blum , Joslin Gemsch , Mark Dycaico
IPC分类号： A61K38/47 , C07H21/00 , C12N15/63 , C12N1/21 , C12N5/00 , C12N1/15 , C12N1/19 , C12N5/06 , C12N5/04 , A01K67/027 , A01H5/00 , A01H5/10 , C12N9/42 , C12N9/14 , C07K16/00 , C07H1/00 , C07K7/08 , C07K14/00 , C12N15/00 , A01H1/00 , C12P19/00 , D21C3/00 , C12P7/08 , A62D3/02 , A61P43/00 , A21D8/04 , C12C11/00 , A23C9/12
CPC分类号： C12N9/2437 , C10L1/02 , C10L1/023 , C10L2200/0423 , C10L2200/0469 , C10L2290/26 , C12P7/10 , C12Y302/01004 , C12Y302/01091 , Y02E50/16 , Y02E50/17
摘要： This invention relates to molecular and cellular biology and biochemistry. In one aspect, the invention provides polypeptides having cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or β-glucosidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or β-glucosidase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts.
摘要翻译：本发明涉及分子和细胞生物学和生物化学。一方面，本发明提供了具有纤维素酶活性的多肽，例如内切葡聚糖酶，纤维二糖水解酶，甘露聚糖酶和/或β-葡糖苷酶活性，编码这些多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。一方面，本发明涉及多肽纤维素酶活性，例如内切葡聚糖酶，纤维二糖水解酶，甘露聚糖酶和/或β-葡糖苷酶活性，包括耐热和耐热活性，以及编码这些酶的多核苷酸，以及制备和使用这些多核苷酸和多肽。本发明的多肽可用于各种药物，农业，食品和饲料加工以及工业环境中。

5. 发明申请

US20080248160A1 XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 有权
标题翻译： XYLANASES，核酸编码它们及其制备和使用方法
公开(公告)号：US20080248160A1
公开(公告)日：2008-10-09
申请号：US10463720
申请日：2003-06-16
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
IPC分类号： A21D8/02 , C12Q1/68 , C07H21/04 , C12P21/06 , C12N9/24 , C12N15/74
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译：本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。此外，还提供了设计新的木聚糖酶的方法及其使用方法。木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。

6. 发明申请

US20080058521A1 Processes for the preparation of compounds 审中-公开
标题翻译：制备化合物的方法
公开(公告)号：US20080058521A1
公开(公告)日：2008-03-06
申请号：US11698258
申请日：2007-01-25
申请人： Lalitha Krishnan , David Blum , Anja Dilley , Sherry Pan , John Potoski , Uresh Shah , Archana Sharma , Henry Strong , Yanzhong Wu , Mei-Yi Zhang , Cynthia Blum
发明人： Lalitha Krishnan , David Blum , Anja Dilley , Sherry Pan , John Potoski , Uresh Shah , Archana Sharma , Henry Strong , Yanzhong Wu , Mei-Yi Zhang , Cynthia Blum
IPC分类号： C07D239/02 , C07D213/02 , C07D241/02 , C07D333/52
CPC分类号： C07D409/12 , C07D213/61 , C07D333/70
摘要： The present invention provides improved synthetic methods for the preparation of compounds that modulate proliferation or differentiation in a cell or tissue.
摘要翻译：本发明提供了改进的调节细胞或组织中增殖或分化的化合物的合成方法。

7. 发明申请

US20070090073A1 System for displaying a sample of a product 审中-公开
标题翻译：用于显示产品样品的系统
公开(公告)号：US20070090073A1
公开(公告)日：2007-04-26
申请号：US11258118
申请日：2005-10-26
申请人： David Blum , Michael Blum , Steven Lorraine , John Gephart
发明人： David Blum , Michael Blum , Steven Lorraine , John Gephart
IPC分类号： A47F5/08
CPC分类号： A47F5/0846
摘要： A system for exhibiting a sample of a product. The system comprises a rail and a display unit. The rail extends from a first end to a second end, and includes at least one display unit engaging portion. The display unit can be removably mounted on the rail, and has a display surface, formed on the front of the display unit, on which the sample of the product can be mounted. The display unit also has at least one rail engaging portion, the at least one rail engaging portion being removably engagable with the at least one display unit engaging portion. The display unit can be removably mounted on the rail directly at a predetermined location between the first end and the second end of the rail through a snap-fit connection between the at least one rail engaging portion and the at least one display unit engaging portion.
摘要翻译：用于展示产品样品的系统。该系统包括轨道和显示单元。轨道从第一端延伸到第二端，并且包括至少一个显示单元接合部分。显示单元可以可拆卸地安装在轨道上，并且具有形成在显示单元的前部上的显示表面，可以在其上安装产品的样品。所述显示单元还具有至少一个导轨接合部分，所述至少一个导轨接合部分可移除地与所述至少一个显示单元接合部分接合。所述显示单元可以通过所述至少一个轨道接合部分和所述至少一个显示单元接合部分之间的卡扣配合连接，直接地在轨道的第一端和第二端之间的预定位置处可移除地安装在轨道上。

8. 发明申请

US20070088172A1 Methods for preparing glutamic acid derivatives 失效
标题翻译：制备谷氨酸衍生物的方法
公开(公告)号：US20070088172A1
公开(公告)日：2007-04-19
申请号：US11484217
申请日：2006-07-11
申请人： Ronald Michalak , Joseph Zeldis , Mel Jennings , David Blum , Timothy Doyle
发明人： Ronald Michalak , Joseph Zeldis , Mel Jennings , David Blum , Timothy Doyle
IPC分类号： C07C237/02
CPC分类号： C07C237/06 , C07C231/12 , C07C237/04 , C07C237/22 , C07C271/22 , C07C2603/18
摘要： The present invention relates to novel methods for the preparation of glutamic acid derivatives and intermediates thereof, and such compounds prepared by the novel methods.
摘要翻译：本发明涉及制备谷氨酸衍生物的新方法及其中间体，以及通过新方法制备的这些化合物。

9. 发明申请

US20050043537A1 Process for preparation of 4-amino-3-quinolinecarbonitriles 失效
标题翻译：制备4-氨基-3-喹啉碳腈的方法
公开(公告)号：US20050043537A1
公开(公告)日：2005-02-24
申请号：US10918947
申请日：2004-08-16
申请人： Karen Sutherland , Gregg Feigelson , Diane Boschelli , David Blum , Henry Strong
发明人： Karen Sutherland , Gregg Feigelson , Diane Boschelli , David Blum , Henry Strong
IPC分类号： C07D215/54 , C07D405/04 , C07D495/04 , C07D215/38
CPC分类号： C07D405/04 , C07D215/54 , C07D495/04
摘要： This invention discloses a process for the preparation of a 4-amino-3-quinolinecarbonitrile comprising combining an amine compound with a cyanoacetic acid and an acid catalyst to yield a cyanoacetamide; condensing the cyanoacetamide with an optionally up to tetra-substituted aniline in an alcoholic solvent and a trialkylorthoformate to yield a 3-amino-2-cyanoacrylamide; combining the 3-amino-2-cyanoacrylamide with phosphorus oxychloride in acetonitrile, butyronitrile, toluene or xylene, optionally in the presence of a catalyst to yield a 4-amino-3-quinolinecarbonitrile and also discloses a process for the preparation of a 7-amino-thieno[3,2-b]pyridine-6-carbonitrile comprising combining a disubstituted 3-amino thiophene with a cyanoacetamide and trialkylorthoformate in an alcoholic solvent to obtain a 3-amino-2-cyanoacrylamide; and combining the 3-amino-2-cyanoacrylamide with phosphorus oxychloride and acetonitrile, butyronitrile, toluene or xylene, optionally in the presence of a catalyst to yield a 7-amino-thieno[3,2-b]pyridine-6-carbonitrile and also discloses a process for the preparation of a 4-amino-3-quinolinecarbonitrile by combining an amine compound with a cyanoacetic acid and a peptide coupling reagent to obtain a suspension; filtering the suspension to yield a cyanoacetamide; condensing the cyanoacetamide with an optionally up to tetra-substituted aniline, an alcoholic solvent, and triethylorthoformate to yield a 3-amino-2-cyanoacrylamide; and combining the 3-amino-2-cyanoacrylamide with phosphorus oxychloride to yield a 4-amino-3-quinolinecarbonitrile.
摘要翻译：本发明公开了一种制备4-氨基-3-喹啉甲腈的方法，包括将胺化合物与氰基乙酸和酸催化剂混合以产生氰基乙酰胺; 将氰基乙酰胺与任选至多四取代的苯胺在醇溶剂和三烷基原甲酸酯中缩合，得到3-氨基-2-氰基丙烯酰胺; 任选在催化剂存在下，将3-氨基-2-氰基丙烯酰胺与三氯氧化磷在乙腈，丁腈，甲苯或二甲苯中的混合，得到4-氨基-3-喹啉腈，并公开了制备7-氨基-2-氰基丙烯酰胺的方法，氨基 - 噻吩并[3,2-b]吡啶-6-甲腈，其包括在醇溶剂中组合二取代的3-氨基噻吩与氰基乙酰胺和三烷基酯，得到3-氨基-2-氰基丙烯酰胺; 并将3-氨基-2-氰基丙烯酰胺与磷酰氯和乙腈，丁腈，甲苯或二甲苯组合，任选在催化剂存在下，得到7-氨基 - 噻吩并[3,2-b]吡啶-6-甲腈和还公开了通过将胺化合物与氰基乙酸和肽偶联剂组合以制备悬浮液来制备4-氨基-3-喹啉腈的方法; 过滤悬浮液，得到氰基乙酰胺; 将氰基乙酰胺与任选的高达四取代的苯胺，醇溶剂和原甲酸三乙酯缩合，得到3-氨基-2-氰基丙烯酰胺; 并将3-氨基-2-氰基丙烯酰胺与磷酰氯组合，得到4-氨基-3-喹啉腈。

10. 发明授权

US08728769B2 Xylanases, nucleic acids encoding them and methods for making and using them 有权
标题翻译：木聚糖酶，编码它们的核酸以及制备和使用它们的方法
公开(公告)号：US08728769B2
公开(公告)日：2014-05-20
申请号：US12402421
申请日：2009-03-11
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
IPC分类号： C12N9/24 , C12N11/00 , C12P19/14 , C12P7/06 , C12P7/02 , C12S3/02 , C12S11/00
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译：本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。此外，还提供了设计新的木聚糖酶的方法及其使用方法。木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。

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