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1. 发明专利

JP2012006895A Melanin production promoter 有权
标题翻译： MELANIN生产促销
公开(公告)号：JP2012006895A
公开(公告)日：2012-01-12
申请号：JP2010146931
申请日：2010-06-28
申请人： Kansai Univ , 学校法人関西大学
发明人： NAGAOKA YASUO , KUMAGAI AYAKO , HORIIE NANAO , TAKEMORI HIROSHI , HORIBE IPPEI , OBATA KATSUYOSHI
IPC分类号： A61K31/352 , A61K8/49 , A61P17/00 , A61Q5/00 , A61Q19/04 , C07D311/30
摘要： PROBLEM TO BE SOLVED: To provide a melanin production promoter having a compound having excellent melanin production promotion effect as an effective component; a gray hair preventive or ameliorative agent having the melanin production promoter as an effective component; and a tanning promoter which is useful as a therapeutic agent for white spot lesion, or as a cosmetic capable of acquiring a sunburn effect without depending on exposure to sunlight (daylight) or the like.SOLUTION: At least one kind of compound selected from a compound group shown by formula (1) is used as an effective component. To put it concretely, following compound are illustrated, namely, Platol, Acacetin, Kaempheride, Fisetin, 4'-O-Methylfisetin, 4'-O-Ethylfisetin, Diosmetin, 3,3',7-O-Acetyl-4'-O-Methylfisetin, 3',5,7-O-Acetyl-Diosmetin, Isoginkgetin and Sciadopitysin.
摘要翻译：解决问题：提供具有优异的黑色素生产促进效果的化合物作为有效成分的黑色素生成促进剂; 具有黑色素生成促进剂作为有效成分的灰发防治剂或改善剂; 以及可用作白斑病变治疗剂的鞣制促进剂，或作为不依赖于阳光（日光）等而获得晒斑效果的化妆品。解决方案：使用选自式（1）所示的化合物基团中的至少一种化合物作为有效成分。具体来说，说明了以下化合物，即Platol，Acacetin，Kaempheride，Fisetin，4'-O-甲基非西汀，4'-O-乙基非丝氨酸，二硫代甜菜碱，3,3'，7-O-乙酰基-4'- O-甲基非丝氨肽，3'，5,7-O-乙酰基二硫代吗啉，异链球蛋白和Sciadopitysin。版权所有（C）2012，JPO＆INPIT

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