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    • 2. 发明授权
    • Increasing the HDL level and the HDL/LDL ratio in human serum by
balancing saturated and polyunsaturated dietary fatty acids
    • 通过平衡饱和和多不饱和膳食脂肪酸来增加人血清中的HDL水平和HDL / LDL比
    • US5843497A
    • 1998-12-01
    • US626461
    • 1996-04-02
    • Kalyana SundramDaniel PerlmanKenneth C. Hayes
    • Kalyana SundramDaniel PerlmanKenneth C. Hayes
    • A21D2/14A21D13/08A23C19/093A23D9/00A23L1/24A23L1/30A61K31/23A61K31/231A61K31/232
    • A23D9/00A21D13/08A21D2/145A23C19/093A23L27/60A23L33/12A61K31/23A61K31/231A61K31/232
    • A method of increasing the HDL concentration and the HDL/LDL concentration ratio in human serum by providing a balance between a sufficient and required proportion of cholesterol-free saturated fatty acids in the daily dietary fat of the human and a sufficient and required, but not excessive, proportion of polyunsaturated fatty acids comprising linoleic acid in dietary fat, while the remaining proportion of fatty acids and energy from the dietary fat is provided by monounsaturated fatty acids comprising oleic acid. The saturated fatty acids must constitute between 20% and 40% by weight of the daily dietary fat based upon dietary fat accounting for 30% of the total dietary energy consumption, and linoleic acid must constitute between 15% and 40% by weight of dietary fat. In this way, the required proportional intake of polyunsaturated fatty acids enhances the formation of HDL from VLDL and/or decreases the clearance of HDL, while an excessive proportional intake of polyunsaturated fatty acids and monounsaturated fatty acids is avoided to assure a sufficient dietary availability of saturated fatty acids which are required for sufficient VLDL synthesis and HDL production.
    • 通过在人的日常饮食脂肪中足够和所需比例的不含胆固醇的饱和脂肪酸之间提供足够的和必需的而不是增加HDL浓度和HDL / LDL浓度比的方法,而不是 过量的,含有亚油酸的多不饱和脂肪酸在饮食脂肪中的比例,而来自膳食脂肪的脂肪酸和能量的剩余比例由包含油酸的单不饱和脂肪酸提供。 基于膳食脂肪占饱和膳食能量的30%,饱和脂肪酸必须占日粮的20%至40%,而亚油酸必须占膳食脂肪的15%至40% 。 以这种方式,所需的多不饱和脂肪酸的比例摄入可增强VLDL的HDL形成和/或降低HDL的清除率,同时避免多不饱和脂肪酸和单不饱和脂肪酸的过量比例摄入,以确保足够的膳食可用性 足够的VLDL合成和HDL生产所需的饱和脂肪酸。
    • 3. 发明授权
    • Increasing the HDL level and the HDL/LDL ratio in human serum with fat
blends
    • 用脂肪混合物提高人血清中的HDL水平和HDL / LDL比
    • US5578334A
    • 1996-11-26
    • US418641
    • 1995-04-07
    • Kalyana SundramDaniel PerlmanKenneth C. Hayes
    • Kalyana SundramDaniel PerlmanKenneth C. Hayes
    • A21D2/14A21D13/08A23C19/093A23D9/00A23L1/24A23L1/30A61K31/23A61K31/231A61K31/232
    • A23D9/00A21D13/08A21D2/145A23C19/093A23L27/60A23L33/12A61K31/23A61K31/231A61K31/232
    • A method of increasing the HDL concentration and the HDL/LDL concentration ratio in human serum by providing a balance between a sufficient and required proportion of cholesterol-free saturated fatty acids in the daily dietary fat of the human and a sufficient and required, but not excessive, proportion of polyunsaturated fatty acids comprising linoleic acid in dietary fat, while the remaining proportion of fatty acids and energy from the dietary fat is provided by monounsaturated fatty acids comprising oleic acid. The saturated fatty acids must constitute between 20% and 40% by weight of the daily dietary fat based upon dietary fat accounting for 30% of the total dietary energy consumption, and linoleic acid must constitute between 15% and 40% by weight of dietary fat. In this way, the required proportional intake of polyunsaturated fatty acids enhances the formation of HDL from VLDL and/or decreases the clearance of HDL, while an excessive proportional intake of polyunsaturated fatty acids and monounsaturated fatty acids is avoided to assure a sufficient dietary availability of saturated fatty acids which are required for sufficient VLDL synthesis and HDL production.
    • 通过在人的日常饮食脂肪中足够和所需比例的不含胆固醇的饱和脂肪酸之间提供足够的和必需的而不是增加HDL浓度和HDL / LDL浓度比的方法,而不是 过量的,含有亚油酸的多不饱和脂肪酸在饮食脂肪中的比例,而来自膳食脂肪的脂肪酸和能量的剩余比例由包含油酸的单不饱和脂肪酸提供。 基于膳食脂肪占饱和膳食能量的30%,饱和脂肪酸必须占日粮的20%至40%,而亚油酸必须占膳食脂肪的15%至40% 。 以这种方式,所需的多不饱和脂肪酸的比例摄入可增强VLDL的HDL形成和/或降低HDL的清除率,同时避免多不饱和脂肪酸和单不饱和脂肪酸的过量比例摄入,以确保足够的膳食可用性 足够的VLDL合成和HDL生产所需的饱和脂肪酸。