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1. 发明申请

WO2009035253A3 NOVEL USE OF SCOPARONE 审中-公开
公开(公告)号：WO2009035253A3
公开(公告)日：2009-03-19
申请号：PCT/KR2008/005324
申请日：2008-09-10
申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION , LEE, In Kyu
发明人： LEE, In Kyu
IPC分类号： A61K31/37
摘要： Disclosed herein are a pharmaceutical composition for inhibiting the proliferation of vascular smooth muscle cells, which contains scoparone as an active ingredient, the use of scoparone for inhibiting the proliferation of vascular smooth muscle cells and a method for inhibiting the proliferation of vascular smooth muscle cells using scoparone. According to the disclosed invention, it has been found that scoparone can inhibit the proliferation of vascular smooth muscle cells by increasing the activity of AMPK. Accordingly, scoparone can be advantageously used as an active ingredient' in drugs for inhibiting the proliferation of vascular smooth muscle cells, particularly preventing or treating blood vessel restenosis.

2. 发明申请

WO2009035251A1 NOVEL USE OF DIMETHYLFUMARATE 审中-公开
标题翻译：二甲基氟的新用途
公开(公告)号：WO2009035251A1
公开(公告)日：2009-03-19
申请号：PCT/KR2008/005322
申请日：2008-09-10
申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION , LEE, In Kyu
发明人： LEE, In Kyu
IPC分类号： A61K31/225
CPC分类号： A61K31/225
摘要： Disclosed are a pharmaceutical composition for inhibiting vascular smooth muscle cell proliferation comprising dimethyl fumarate as an effective ingredient, use of dimethyl fumarate for inhibiting vascular smooth muscle cell proliferation, and a method of inhibiting vascular smooth muscle cell proliferation employing the same. Through the present invention, it was found that dimethyl fumarate could inhibit vascular smooth muscle cell proliferation by increasing the activity of AMPK. Accordingly, dimethyl fumarate can be usefully used as an effective ingredient of a medicine for inhibiting vascular smooth muscle cell proliferation.
摘要翻译：公开了一种用于抑制血管平滑肌细胞增殖的药物组合物，其包含富马酸二甲酯作为有效成分，使用富马酸二甲酯抑制血管平滑肌细胞增殖，以及使用该药物组合物抑制血管平滑肌细胞增殖的方法。通过本发明，通过增加AMPK的活性，发现富马酸二甲酯可以抑制血管平滑肌细胞增殖。因此，富马酸二甲酯可有效地用作抑制血管平滑肌细胞增殖的药物的有效成分。

3. 发明公开

EP3834828A1 COMPOSITION FOR PREVENTING OR TREATING VASCULAR OR CARDIAC VALVULAR CALCIFICATION, CONTAINING THIAMINE DERIVATIVE 有权
公开(公告)号：EP3834828A1
公开(公告)日：2021-06-16
申请号：EP19846789.6
申请日：2019-07-22
申请人： Kyungpook National University Industry-Academic Cooperation Foundation
发明人： LEE, In Kyu , JEON, Jae Han , OH, Chang Joo , LEE, Ji Min
IPC分类号： A61K31/505 , A61P9/00 , A23L33/10
摘要： The present invention relates to: a pharmaceutical composition for preventing or treating vascular or cardiac valvular calcification, containing a thiamine derivative or a pharmaceutically acceptable salt thereof; and a food composition for alleviating vascular or cardiac valvular calcification, containing a thiamine derivative or a salt thereof, and the compositions of the present invention can be effectively used for a use of preventing, treating or alleviating vascular or cardiac valvular calcification.

4. 发明公开

EP3875092A1 COMPOSITION FOR PREVENTION OR TREATMENT OF MACULAR DEGENERATION 审中-实审
公开(公告)号：EP3875092A1
公开(公告)日：2021-09-08
申请号：EP19878702.0
申请日：2019-10-30
申请人： Kyungpook National University Industry-Academic Cooperation Foundation
发明人： PARK, Dong Ho , LEE, In Kyu
IPC分类号： A61K31/506 , A61K9/00 , A61P27/02 , A23L33/10
摘要： The present disclosure pertains to a pharmaceutical composition comprising fursultiamine or a salt thereof for prevention or treatment of macular degeneration. Fursultiamine decreases the upregulated expression of HIF-1α in retinal pigment epithelial cells and suppresses the growth of choroidal vascular endothelial cells. The pharmaceutical composition comprising fursultiamine or salts thereof according to the present disclosure can be used as a therapeutic agent for various neovascular ocular diseases.

5. 发明公开

EP3858359A1 COMPOSITION, COMPRISING THIAMINE DERIVATIVE, FOR PREVENTION OR TREATMENT OF HYPERCORTISOLEMIA 有权
公开(公告)号：EP3858359A1
公开(公告)日：2021-08-04
申请号：EP19864600.2
申请日：2019-09-30
申请人： Kyungpook National University Industry-Academic Cooperation Foundation
发明人： LEE, In Kyu , JEON, Jae Han , KANG, Hyeon-Ji
IPC分类号： A61K31/51 , A61P5/38 , A61P9/12 , A61P3/10 , A61P3/04 , A23L33/10
摘要： The present invention relates to a composition for prevention or treatment of hypercortisolemia, the composition comprising allithiamine, fursultiamine, and benfotiamine, which are all derivatives of thiamine, or a mixed composition thereof. The composition for prevention or treatment of hypercortisolemia of the present invention can effectively treat or alleviate symptoms or disorders resulting from excessive secretion of cortisol, without surgical operations, and does not exhibit side effects caused by conventional medications.

6. 发明申请

WO2008054172A1 METHOD FOR DETERMINING MODULATION AND CODING SCHEME 审中-公开
标题翻译：确定调制和编码方案的方法
公开(公告)号：WO2008054172A1
公开(公告)日：2008-05-08
申请号：PCT/KR2007/005520
申请日：2007-11-02
申请人： LG ELECTRONICS INC. , CHUN, Jin Young , IHM, Bin Chul , LEE, In Kyu , MOON, Seong Hyeon , SEONG, Chang Gyeong
发明人： CHUN, Jin Young , IHM, Bin Chul , LEE, In Kyu , MOON, Seong Hyeon , SEONG, Chang Gyeong
IPC分类号： H04B7/26
CPC分类号： H04L5/0007 , H04L25/0202 , H04L27/2626 , H04L27/2647
摘要： There is provided a method of determining a Modulation and Coding Scheme (MCS). The method includes predicting an error rate of a symbol and determining a MCS of the symbol using the error rate. Since a MCS level is determined using an estimated error rate and user data is scheduled, multi-user diversity gain can be obtained and the transmission rate can be improved.
摘要翻译：提供了一种确定调制和编码方案（MCS）的方法。该方法包括：使用错误率预测符号的错误率并确定符号的MCS。由于使用估计的误码率来确定MCS级别，并且调度用户数据，因此可以获得多用户分集增益，并且可以提高传输速率。

7. 发明申请

WO2008133409A1 FEEDBACK DRIVING SYSTEM AND DRIVING METHOD FOR MAINTAINING GLOW DISCHARGE OF A FLAT BACKLIGHT 审中-公开
标题翻译：用于维护平板背光的玻璃放电的反馈驱动系统和驱动方法
公开(公告)号：WO2008133409A1
公开(公告)日：2008-11-06
申请号：PCT/KR2008/001684
申请日：2008-03-26
申请人： SAMHWA YANG HENG CO., LTD. , PARK, Joung Hu , LEE, In Kyu , BAEK, Jong Bok , CHO, Bo Hyung
发明人： PARK, Joung Hu , LEE, In Kyu , BAEK, Jong Bok , CHO, Bo Hyung
IPC分类号： H05B41/24
CPC分类号： H05B41/388
摘要： A feedback driving system for a flat lamp, the feedback driving system including a driving circuit which supplies driving power to a flat lamp; a sensing unit which measures power applied to the flat lamp; and a control unit which analyzes the measured value from the sensing unit, and when it is analyzed that the flat lamp is to change into a discharge contraction state or partial discharge state, controls the driving circuit such that the power applied to the flat lamp is maintained at a predetermined value. The feedback driving system, which feedback-controls the driving circuit by measuring a voltage applied to the flat lamp or a current flowing through the flat lamp, can maintain the power applied to the flat lamp within a predetermined range such that the flat lamp does not change into the discharge contraction state or partial discharge state, but can maintain the glow discharge.
摘要翻译：一种用于平板灯的反馈驱动系统，所述反馈驱动系统包括向平板灯提供驱动电力的驱动电路; 感测单元，其测量施加到所述扁平灯的功率; 以及控制单元，其分析来自感测单元的测量值，并且当分析扁平灯变成放电收缩状态或局部放电状态时，控制驱动电路，使得施加到平面灯的电力为保持在预定值。通过测量施加到平板灯上的电压或流过平面灯的电流来反馈控制驱动电路的反馈驱动系统可以将施加在平板灯上的功率保持在预定范围内，使得平板灯不变成放电收缩状态或局部放电状态，但可以保持辉光放电。

8. 发明申请

WO2002098415A1 MEDICINE FOR TREATING OBESITY 审中-公开
标题翻译：用于治疗肥胖的药物
公开(公告)号：WO2002098415A1
公开(公告)日：2002-12-12
申请号：PCT/KR2002/001072
申请日：2002-06-05
申请人： PARK, Joong-Yeol , HONG, Sung-Kwan , LEE, In Kyu , LEE, Ki-Up
发明人： PARK, Joong-Yeol , HONG, Sung-Kwan , LEE, In Kyu , LEE, Ki-Up
IPC分类号： A61K31/381
CPC分类号： A61K31/381
摘要： The present invention relates to a new medicine for treating obesity, and more particularly to a medicine for treating obesity comprising α- lipoic acid. Moreover the present invention provides compositions for treating obesity or decreasing appetite comprising α- lipoic acid, pharmaceutically acceptable carriers and additives.
摘要翻译：本发明涉及一种用于治疗肥胖症的新药，更具体地涉及一种治疗肥胖症的药物，其包含DOLLAR g（a-）硫辛酸。此外，本发明提供了用于治疗肥胖或减少食欲的组合物，其包含DOLLAR g（a-）硫辛酸，药学上可接受的载体和添加剂。

9. 发明申请

WO2006068386A1 SYNTHETIC METHOD OF PHENYLCARBAMATE DERIVATIVE 审中-公开
标题翻译：苯甲酰胺衍生物的合成方法
公开(公告)号：WO2006068386A1
公开(公告)日：2006-06-29
申请号：PCT/KR2005/004364
申请日：2005-12-16
申请人： DONG KOOK PHARM. CO., LTD , CHA, Kyung Hoi , LIM, Dae Sung , LEE, Han Won , LEE, In Kyu , PAENG, Hyun Ki , PARK, Seun Soon
发明人： CHA, Kyung Hoi , LIM, Dae Sung , LEE, Han Won , LEE, In Kyu , PAENG, Hyun Ki , PARK, Seun Soon
IPC分类号： C07C231/14
CPC分类号： C07C269/00 , C07C271/44
摘要： Disclosed herein is a method for synthesizing the compound of Formula 1 or an acid addition salt thereof: The method comprises the steps of subjecting the compound of Formula 7 to N -methylation to obtain the compound of Formula 8 or an acid addition salt thereof: and subjecting the compound of Formula 8 or an acid addition salt thereof to O -carbamoylation to obtain the compound of Formula 1 or an acid addition salt thereof.
摘要翻译：本文公开了一种合成式1化合物或其酸加成盐的方法：该方法包括使式7化合物进行N-甲基化以获得式8化合物或其酸加成盐的步骤：和使式8的化合物或其酸加成盐进行O-氨基甲酰化，得到式1的化合物或其酸加成盐。

10. 发明申请

WO2011136473A2 METHOD FOR AVOIDING INTERFERENCE IN WIRELESS COMMUNICATION SYSTEM AND APPARATUS FOR THE SAME 审中-公开
标题翻译：用于避免无线通信系统干扰的方法及其设备
公开(公告)号：WO2011136473A2
公开(公告)日：2011-11-03
申请号：PCT/KR2011/001995
申请日：2011-03-23
申请人： LG ELECTRONICS INC. , KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION , LEE, Dae Won , LEE, In Kyu , LEE, Kyoung Jae , SEOK, Yong Ho
发明人： LEE, Dae Won , LEE, In Kyu , LEE, Kyoung Jae , SEOK, Yong Ho
IPC分类号： H04B7/04 , H04B15/00
CPC分类号： H04B7/0619 , H04B7/0439 , H04B7/0452 , H04B7/0465
摘要： Disclosed are a method for avoiding interference in a wireless communication system and an apparatus supporting the same. The method for avoiding interference by an access point (AP) in a wireless local area network (WLAN) system includes: acquiring first effective channel information between the AP and a first station (STA) targeted for multi user-multiple input multiple output (MU-MIMO) transmission; acquiring second effective channel information between the AP and a second STA that receives data from a third STA during the MU-MIMO transmission; and performing the MU-MIMO transmission to a target STA including the first STA by beamforming based on an interference-avoiding precoding that eliminates interference due to data transmission from the third STA to the second STA from a receiving signal of the first STA and interference due to the MU-MIMO transmission from a receiving signal of the second STA.
摘要翻译：公开了一种避免无线通信系统中的干扰的方法及其支持装置。用于避免无线局域网（WLAN）系统中的接入点（AP）的干扰的方法包括：在AP与针对多用户多输入多输出（MU）的第一站（STA）之间获取第一有效信道信息 -MIMO）传输; 在所述AP与在所述MU-MIMO传输期间从第三STA接收数据的第二STA获取第二有效信道信息; 以及基于干扰避免预编码，通过波束成形对包括第一STA的目标STA进行MU-MIMO传输，该干扰避免预编码消除了由于第一STA的接收信号导致的从第三STA到第二STA的数据传输的干扰，从第二STA的接收信号到MU-MIMO传输。

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