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1. 发明申请

WO2009150593A1 APPARATUS FOR DETERMINING A PROPERTY OF AN OBJECT 审中-公开
标题翻译：用于确定对象的属性的装置
公开(公告)号：WO2009150593A1
公开(公告)日：2009-12-17
申请号：PCT/IB2009/052388
申请日：2009-06-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , THILWIND, Rachel, E. , SUIJVER, Jan, F. , DELADI, Szabolcs
发明人： THILWIND, Rachel, E. , SUIJVER, Jan, F. , DELADI, Szabolcs
IPC分类号： A61B5/00
CPC分类号： A61B8/12 , A61B5/0084 , A61B5/0095 , A61B6/12 , A61B6/4423 , A61B18/1492 , A61B2017/00106
摘要： The present invention relates to an apparatus for determining a property of an object (2), wherein the apparatus comprises a casing (31) comprising an inner region (33) for receiving an object influencing unit (3) for influencing the object (2) and an outer region (35) enclosing the inner region (33). The outer region (35) comprises a light transmission unit (36) for transmitting acoustic wave generating light to the object (2) for coupling the acoustic wave generating light into the object (2) for generating an acoustic wave within the object (2). Furthermore, the outer region (35) comprises an acoustic wave sensing element (37) for sensing the acoustic wave. The casing is preferentially a sheath surrounding the inner region (33), wherein preferentially in the wall of the sheath at least one cavity (39) defines the outer region (35).
摘要翻译：本发明涉及一种用于确定物体（2）的性质的装置，其中该装置包括一个壳体（31），该壳体包括用于接收用于影响物体（2）的物体影响单元（3）的内部区域（33）和封闭所述内部区域（33）的外部区域（35）。外部区域（35）包括用于将声波产生光传送到物体（2）的光传输单元（36），用于将声波产生光耦合到物体（2）中，用于在物体（2）内产生声波，。此外，外部区域（35）包括用于感测声波的声波感测元件（37）。壳体优选地是围绕内部区域（33）的护套，其中优选地在护套的壁中至少一个空腔（39）限定外部区域（35）。

2. 发明申请

WO2009090588A1 APPARATUS, METHOD AND COMPUTER PROGRAM FOR APPLYING ENERGY TO AN OBJECT 审中-公开
标题翻译：用于将能量应用于对象的装置，方法和计算机程序
公开(公告)号：WO2009090588A1
公开(公告)日：2009-07-23
申请号：PCT/IB2009/050102
申请日：2009-01-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , THILWIND, Rachel, E. , SUIJVER, Jan, F. , DELADI, Szabolcs
发明人： THILWIND, Rachel, E. , SUIJVER, Jan, F. , DELADI, Szabolcs
IPC分类号： A61B5/00 , A61B18/00
CPC分类号： A61B18/1492 , A61B5/0066 , A61B5/0075 , A61B5/0084 , A61B5/0095 , A61B18/02 , A61B18/24 , A61B2017/00057 , A61B2017/00106
摘要： The present invention relates to an apparatus for applying energy to an object. The invention relates further to a corresponding method and to a corresponding computer program. The apparatus comprises a catheter (3), which includes an energy applying unit (17, 18) for applying energy to the object (2) and a photoacoustic measurement unit (20, 21) for photo acoustically sensing the object (2). The photoacoustic measurement unit comprises preferentially a reflecting element (20), which is movable by an acoustic wave, wherein the apparatus comprises at least one optical fiber (21) located within the catheter (3) for guiding light to and/or from the movable reflecting element (20). The acoustic wave is preferentially measured by determining a phase shift of light reflected from the reflecting element (20), which moves, if the reflecting element is exposed to the acoustic wave.
摘要翻译：本发明涉及一种向物体施加能量的装置。本发明进一步涉及相应的方法和相应的计算机程序。该装置包括导管（3），其包括用于向物体（2）施加能量的能量施加单元（17,18）和用于光学感测物体（2）的光声测量单元（20,21）。光声测量单元优选地包括可由声波移动的反射元件（20），其中所述设备包括位于所述导管（3）内的至少一个光纤（21），用于将光导向和/或不移动反射元件（20）。如果反射元件暴露于声波，则通过确定从反射元件（20）反射的光的相移优先测量声波，所述相移将移动。

3. 发明申请

WO2010082146A1 MONITORING APPARATUS FOR MONITORING AN ABLATION PROCEDURE 审中-公开
标题翻译：监测装置的监测程序
公开(公告)号：WO2010082146A1
公开(公告)日：2010-07-22
申请号：PCT/IB2010/050059
申请日：2010-01-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , HARKS, Erik, A. , DELADI, Szabolcs , SUIJVER, Jan, F. , JANKOVIC, Ladislav , SHI, Yan, S. , RENSEN, Wouter, H., J. , BARLEY, Maya, E. , VAN DER VAART, Nijs, C.
发明人： HARKS, Erik, A. , DELADI, Szabolcs , SUIJVER, Jan, F. , JANKOVIC, Ladislav , SHI, Yan, S. , RENSEN, Wouter, H., J. , BARLEY, Maya, E. , VAN DER VAART, Nijs, C.
IPC分类号： A61B8/08 , A61B8/12 , A61B18/14
CPC分类号： A61B8/0858 , A61B8/12 , A61B8/445 , A61B8/486 , A61B18/02 , A61B18/1442 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00106 , A61B2018/00577 , A61B2018/00738 , A61B2090/376 , A61B2090/3784 , A61B2218/002
摘要： The present invention relates to a monitoring apparatus(101) for monitoring an ablation procedure. The monitoring apparatus (101) comprises an ultrasound signal providing unit for providing an ultrasound signal that depends on received echo series of an object (4) that is ablated. The monitoring apparatus (101) further comprises an ablation depth determination unit (103) for determining an ablation depth from the provided ultrasound signal. The ablation depth can be determined directly from the ultrasound signal and is an important parameter while performing an ablation procedure. For example, it can be used for determining the progress of ablation within the object (4) and for determining when the ablation has reached a desired progression.
摘要翻译：本发明涉及一种用于监测消融程序的监测装置（101）。监视装置（101）包括：超声信号提供单元，用于提供取决于被消融的物体（4）的接收回波序列的超声信号。监测装置（101）还包括用于根据所提供的超声信号确定消融深度的消融深度确定单元（103）。消融深度可以直接从超声信号确定，并且是执行消融过程的重要参数。例如，它可以用于确定对象（4）内的消融进展并确定消融何时达到期望的进程。

4. 发明申请

WO2008146212A1 HYDROGEL BASED SENSOR PROBE FOR DETECTING AN ENVIRONMENTAL STATE 审中-公开
标题翻译：用于检测环境状态的基于HYDROGEL的传感器探测器
公开(公告)号：WO2008146212A1
公开(公告)日：2008-12-04
申请号：PCT/IB2008/052019
申请日：2008-05-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , HENDRIKS, Bernardus, H., W. , DELADI, Szabolcs , KURT, Ralph , SUIJVER, Jan, F.
发明人： HENDRIKS, Bernardus, H., W. , DELADI, Szabolcs , KURT, Ralph , SUIJVER, Jan, F.
IPC分类号： G01N21/77
CPC分类号： G01N21/7703 , A61B5/0084 , A61B5/14539 , G01N2021/772 , G01N2021/7723 , G01N2021/773 , G01N2021/7779
摘要： The invention relates to a sensor probe (100,110,120,130,140,150) for detecting an environmental state within a bodily lumen. The sensor probe (100,110,120,130,140,150) having an elongated body (9) comprises an optical guide (1) having an outcoupling surface (11),which is part of an end surface (3) of the elongated body (9), facing a reflective surface of an overhanging part (22,42,52,62), a photodetector which detects a property of light which is composed of light (32) in the optical guide (1) that is reflected from the outcoupling surface (11) of the optical guide (1) and of light (33) in the optical guide (1) that is reflected from the overhanging part (22,42,52,62), and a hydrogel material(2) of which a property changes when getting into contact with an environmental material and/or when detecting an environmental change, and which is provided between the end surface (3) of the elongated body (9)and the overhanging part (22,42,52,62). In this way a sensor probe (100,110,120,130,140,150) is provided that, because of its compactness, can be applied inside the bodily lumen for detecting and characterizing parameters that are vital indicators for the state of the human or animal body, and to which the hydrogel material (2) is responsive.
摘要翻译：本发明涉及一种用于检测体腔内的环境状态的传感器探针（100,110,120,130,140,150）。具有细长主体（9）的传感器探针（100,110,130,140,150）包括具有外耦合表面（11）的光导（1），该外耦合表面（11）是细长主体（9）的端表面（3）的一部分，面向反射表面突出部分（22,42,52,62）的光检测器，其检测由光导（1）中的光（32）组成的光的属性，所述光从光耦合表面（11）反射在导光体（1）中从突出部分（22,42,52,62）反射的导光体（1）和光（33）以及在接触时性质发生变化的水凝胶材料（2）和环境材料和/或当检测到环境变化时，并且设置在细长体（9）的端面（3）与伸出部分（22,42,52,62）之间。以这种方式，提供传感器探针（100,110,120,130,140,150），由于其紧凑性，可以在身体内部施加以检测和表征作为人或动物体状态的重要指标的参数，并且将水凝胶材料（2）有反应。

5. 发明申请

WO2009090585A1 FLUID LENS WITH PRESSURE RELEASE SYSTEM 审中-公开
标题翻译：带压力释放系统的流体镜
公开(公告)号：WO2009090585A1
公开(公告)日：2009-07-23
申请号：PCT/IB2009/050098
申请日：2009-01-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , SUIJVER, Jan, F. , KUIPER, Stein , HENDRIKS, Bernardus, H., W. , DELADI, Szabolcs , RADEMAKERS, Antonius, J., J. , VAN DER VLEUTEN, Cornelius, A., N., M. , WEEKAMP, Johannes, W. , BIERHOFF, Waltherus, C., J.
发明人： SUIJVER, Jan, F. , KUIPER, Stein , HENDRIKS, Bernardus, H., W. , DELADI, Szabolcs , RADEMAKERS, Antonius, J., J. , VAN DER VLEUTEN, Cornelius, A., N., M. , WEEKAMP, Johannes, W. , BIERHOFF, Waltherus, C., J.
IPC分类号： G02B3/14 , G02B7/00 , G02B23/24
CPC分类号： G02B7/008 , A61B1/0019 , G02B3/14 , G02B23/2407
摘要： Fluid lens system, e.g. for medical imaging or medical treatment, with a container enclosing a fluid arranged to refract incoming waves. A pressure release mechanism is in contact with the fluid so as to compensate changes in its volume due to thermal variations, e.g. during high temperature medical cleaning. This pressure release mechanism is positioned within a pathway of incoming waves. In preferred embodiments a fluid container connected via a tube to the fluid as a reservoir, is arranged within or outside the container, e.g. beyond an image sensor. Alternatively, an easily compressible body, e.g. a small closed metal bellows enclosing a gas, is positioned inside the fluid to absorb volume changes by compression. In both embodiments, the pressure release elements are preferably positioned in a peripheral part of the pathway of incoming waves to not affect performance of the lens. In another aspect, a fluid lens includes a container with an inner container part that fits inside an outer container part, wherein the inner container part is in rigid connection to at least a one boundary arranged for penetration of incoming waves. The pressure release mechanism is positioned within the outer container part, and it is in contact with the fluid so as to compensate changes in volume of the fluid due to thermal variations. In one embodiment the inner and outer container parts are arranged for relative one-dimensional movement and fluid tight interconnected. In another embodiment, a fluid filled cavity is formed between the inner and outer container parts, and this cavity houses a compressible body. The lens systems are suited for applications such as medical endoscopes, catheters and needles, optically as well as acoustically based.
摘要翻译：流体透镜系统，例如用于医疗成像或医疗处理，容器包围布置成折射入射波的流体。压力释放机构与流体接触，以便补偿由于热变化引起的体积变化，例如，在高温医疗清洗过程中。该压力释放机构位于入射波的通路内。在优选实施例中，经由管连接到作为储存器的流体的流体容器设置在容器内或外部，例如，超越图像传感器。或者，容易压缩的主体，例如，围绕气体的小封闭金属波纹管位于流体内部以通过压缩吸收体积变化。在两个实施例中，压力释放元件优选地定位在入射波通路的周边部分中，从而不影响透镜的性能。在另一方面，一种流体透镜包括具有内部容器部分的容器，该内部容器部分装配在外部容器部分内部，其中内部容器部分刚好连接至布置成用于穿透入射波的至少一个边界。压力释放机构位于外部容器部分内，并且与流体接触以便补偿由于热变化引起的流体体积的变化。在一个实施例中，内部和外部容器部件布置用于相对一维运动并且流体密封互连。在另一个实施例中，在内部和外部容器部分之间形成流体填充空腔，并且该空腔容纳可压缩体。透镜系统适用于诸如医用内窥镜，导管和针的应用，光学和声学基础。

6. 发明申请

WO2010140069A1 VISUALIZATION APPARATUS 审中-公开
标题翻译：可视化装置
公开(公告)号：WO2010140069A1
公开(公告)日：2010-12-09
申请号：PCT/IB2010/051919
申请日：2010-05-03
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , BARLEY, Maya, E. , DELADI, Szabolcs , HARKS, Godefridus, A. , SUIJVER, Jan, F. , MEGENS, Mischa
发明人： BARLEY, Maya, E. , DELADI, Szabolcs , HARKS, Godefridus, A. , SUIJVER, Jan, F. , MEGENS, Mischa
IPC分类号： A61B19/00 , A61B18/14
CPC分类号： A61B90/36 , A61B18/1492 , A61B34/20 , A61B2017/00106 , A61B2090/062 , A61B2090/065 , A61B2090/376 , G06F19/00
摘要： The invention relates to a visualization apparatus for visualizing aquality of applying energy to an object. The quality of applying energy at a location on the object (3) is visualized based on a) a provided image of the object and b) a provided quality value representing the quality of applying energy to the object at the location on the object (3), wherein a visual property assigning unit (9) assigns a visual property to the location depending on the quality value and a display(10) displays the provided image and the assigned visual property at the location on the object shown in the image.In general a person who applies energy to the object is focused on the location at which energy is applied. Since quality information is shown at the location on which the person is already focused, the quality dependent information can easily be absorbed by the person.
摘要翻译：本发明涉及一种可视化装置，用于将能量施加到物体上的可视化。基于a）所提供的对象图像和b）提供的质量值，表示在物体上的位置处对物体施加能量的质量（3），可视化对象（3）上的位置处的能量的质量），其中视觉特性分配单元（9）根据所述质量值向所述位置分配视觉特性，并且显示器（10）在所述图像中所示的对象上的位置处显示所提供的图像和所分配的视觉特性。将能量施加到物体的人一般集中在施加能量的位置上。由于质量信息显示在人已经聚焦的位置，所以质量依赖信息可以容易地被人吸收。

7. 发明申请

WO2010103423A2 CATHETER, APPARATUS, METHOD AND COMPUTER PROGRAM FOR APPLYING ENERGY TO AN OBJECT 审中-公开
标题翻译：用于将能量应用于物体的导管，设备，方法和计算机程序
公开(公告)号：WO2010103423A2
公开(公告)日：2010-09-16
申请号：PCT/IB2010/050886
申请日：2010-03-02
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , WEEKAMP, Johannes, W. , DELADI, Szabolcs , BARLEY, Maya, E. , RADEMAKERS, Antonius, J., J. , SUIJVER, Jan, F.
发明人： WEEKAMP, Johannes, W. , DELADI, Szabolcs , BARLEY, Maya, E. , RADEMAKERS, Antonius, J., J. , SUIJVER, Jan, F.
IPC分类号： A61B18/14 , A61B8/12 , A61M25/10
CPC分类号： A61B8/4461 , A61B8/12 , A61B8/445 , A61B8/4472 , A61B18/1492 , A61B2018/00214 , A61B2018/00773 , A61B2018/1861 , A61B2090/3782 , A61M25/10
摘要： The present invention relates to a catheter for applying energy to an object. The catheter (5) has a longitudinal axis (7) and includes an energy applying unit (30) for applying energy to the object and a sensing unit (20) for sensing the object in a sensing direction (23). The sensing unit(20) is adapted to be rotatable with respect to the catheter (5) such that the angle (Î±) between the sensing direction (23) of the sensing unit (20) and the longitudinal axis (7) of the catheter (5) is adjustable. The sensing unit (20) can be adjusted during the application of energy to the object such that the sensing direction (23) of the sensing unit (20) points to the site to which the energy is applied, regardless of the angle that the catheter tip forms with the surface of the object at that site.
摘要翻译：本发明涉及一种用于向物体施加能量的导管。导管（5）具有纵向轴线（7）并且包括用于向物体施加能量的能量施加单元（30）和用于沿感测方向（23）感测物体的感测单元（20）。感测单元（20）适于相对于导管（5）旋转，使得感测单元（20）的感测方向（23）与纵向轴线（7）之间的角度（θcirc; 的导管（5）是可调节的。在向对象施加能量期间可以调节感测单元（20），使得感测单元（20）的感测方向（23）指向施加能量的位置，而不管导管尖端与该位置处的物体表面形成。

8. 发明申请

WO2010055443A1 ACOUSTICAL SWITCH AND CATHETER COMPRISING ACOUSTICAL SWITCH 审中-公开
标题翻译：声学开关和导管包括声学开关
公开(公告)号：WO2010055443A1
公开(公告)日：2010-05-20
申请号：PCT/IB2009/054907
申请日：2009-11-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , DELADI, Szabolcs , SUIJVER, Jan, F. , HARKS, Godefridus, A. , WEEKAMP, Johannes, W. , RADEMAKERS, Antonius, J., J. , BARLEY, Maya, E.
发明人： DELADI, Szabolcs , SUIJVER, Jan, F. , HARKS, Godefridus, A. , WEEKAMP, Johannes, W. , RADEMAKERS, Antonius, J., J. , BARLEY, Maya, E.
IPC分类号： A61B8/12 , G10K11/28 , G10K11/30
CPC分类号： A61B8/4461 , A61B8/12 , A61B8/445 , A61B18/1492 , G10K11/28
摘要： The invention relates to an acoustical switch wherein the idea to the ultrasound propagation direction may be changes without moving the switch. The switch device comprises two sheets of acoustically transparent material. The sheets constitute opposite walls of a housing. The switch device further comprises one or more orifices for allowing conduction of fluid into and/or out of said housing. The switch device may be made reflective by filling the housing with a gas via the one or more orifices. Moreover, the switch device may be made transmissive to ultrasound by filling the housing with a liquid via the one or more orifices and/or by subjecting the housing to underpressure via the one or more orifices. The acoustical switch device fits well within a catheter, which has severe dimensional limitations.
摘要翻译：本发明涉及一种声学开关，其中超声波传播方向的想法可以是不改变开关而改变的。开关装置包括两片声透明材料。纸张构成外壳的相对壁。开关装置还包括用于允许流体进入和/或离开所述壳体的一个或多个孔。开关装置可以通过经由一个或多个孔口用气体填充壳体来制成反射性的。此外，开关装置可以通过经由一个或多个孔口填充液体的壳体和/或经由一个或多个孔口对壳体进行负压来对超声波进行透射。声学开关装置很好地配合在具有严格尺寸限制的导管内。

9. 发明申请

WO2010131178A1 APPARATUS, METHOD AND COMPUTER PROGRAM FOR DETERMINING A PROPERTY OF A HEART 审中-公开
标题翻译：用于确定心脏属性的装置，方法和计算机程序
公开(公告)号：WO2010131178A1
公开(公告)日：2010-11-18
申请号：PCT/IB2010/052040
申请日：2010-05-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , HARKS, Godefridus, A. , DELADI, Szabolcs , DE BOER, Bart, M. , BARLEY, Maya, E. , SUIJVER, Jan, F.
发明人： HARKS, Godefridus, A. , DELADI, Szabolcs , DE BOER, Bart, M. , BARLEY, Maya, E. , SUIJVER, Jan, F.
IPC分类号： A61B5/00 , A61B5/06 , A61B5/11 , A61B8/12 , A61B18/14
CPC分类号： A61B5/1107 , A61B5/0073 , A61B5/0084 , A61B5/0507 , A61B5/053 , A61B5/061 , A61B5/062 , A61B5/6852 , A61B8/12 , A61B8/445 , A61B18/02 , A61B18/1492 , A61B18/18 , A61B90/39 , A61B2017/00106 , A61B2218/002 , A61B2562/0209
摘要： The present invention relates to an apparatus for determining a property of a heart. The apparatus comprises a catheter (5), which comprises a first property sensing unit for sensing a contraction signal indicative of a reoccurring local contraction of the heart (2) at a sensing site of the heart (2). The apparatus further comprises a first property determining unit (8) for determining the reoccurring local contraction of the heart (2) at the sensing site from the sensed contraction signal as a first property of the heart (2). The reoccurring local contraction provides information about the heart (2), which can be used for a better and/or more reliable characterization of the heart (2).
摘要翻译：本发明涉及一种用于确定心脏特性的装置。该装置包括导管（5），其包括第一特性感测单元，用于感测指示在心脏（2）的感测位置处心脏（2）的再次出现的局部收缩的收缩信号。该装置还包括第一属性确定单元（8），用于根据感测到的收缩信号确定心脏（2）在感测位置处的再次出现的局部收缩，作为心脏（2）的第一属性。复发的局部收缩提供了关于心脏（2）的信息，其可以用于更好和/或更可靠地表征心脏（2）。

10. 发明申请

WO2010086779A2 AN ACOUSTIC DEVICE FOR ULTRASONIC IMAGING 审中-公开
标题翻译：用于超声波成像的声音设备
公开(公告)号：WO2010086779A2
公开(公告)日：2010-08-05
申请号：PCT/IB2010/050309
申请日：2010-01-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , DELADI, Szabolcs , SUIJVER, Jan, F. , MARESCA, David
发明人： DELADI, Szabolcs , SUIJVER, Jan, F. , MARESCA, David
IPC分类号： G10K11/30
CPC分类号： G10K11/30
摘要： The present invention relates to an acoustic device for ultrasonic imaging of an object (21). The device comprises an acoustic transducer (10 and an acoustic lens (20) arranged to variably refract the said acoustic pulse to and/or from the acoustic transducer. The acoustic lens comprising a first (L1) and a second fluid (L2) being separated by an acoustic interface (7), the normal of the said acoustic interface forming a relative angle of incidence (AI) with the said acoustic pulse, e.g. an electrowetting lens. The first and the second fluid of the acoustic lens (20) are specifically chosen so that the acoustic interface (7) has a reflection minima at a non-zero relative angle of incidence (AI). The invention is advantageous for obtaining an improved acoustic device having a substantially lower reflection in a broader interval of incidence angles as compared to hitherto seen ultrasonic imaging utilising acoustic lenses with two or more fluids as the active acoustic refracting entities.
摘要翻译：本发明涉及一种用于物体（21）的超声波成像的声学装置。该装置包括声换能器（10和声透镜），该声透镜被布置成可将声脉冲可变地折射到声换能器和/或从该声换能器。声学透镜包括分离的第一（L1）和第二流体（L2）通过声学接口（7），所述声学接口的法线形成与所述声学脉冲（例如电润湿透镜）的相对入射角（AI），声透镜的第一和第二流体被选择为使得声学界面（7）具有非零相对入射角（AI）的反射最小值。本发明有利于获得具有较大反射率的改进的声学装置，其在更宽的入射角度上比较迄今为止已经看到利用具有两种或多种流体的声透镜作为主动声学折射实体的超声成像。

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