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1. 发明申请

WO2011039692A2 MR IMAGING USING MULTI-CHANNEL RF EXCITATION 审中-公开
标题翻译： MR成像使用多通道RF激励
公开(公告)号：WO2011039692A2
公开(公告)日：2011-04-07
申请号：PCT/IB2010/054339
申请日：2010-09-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , FUDERER, Miha , ROZIJN, Thomas, Hendrik , KATSCHER, Ulrich , NEHRKE, Kay , HARVEY, Paul, Royston
发明人： FUDERER, Miha , ROZIJN, Thomas, Hendrik , KATSCHER, Ulrich , NEHRKE, Kay , HARVEY, Paul, Royston
CPC分类号： G01R33/5612 , G01R33/246 , G01R33/5659
摘要： The invention relates to a magnetic resonance imaging apparatus comprising an array of two or more RF antennas(9) for transmitting RF pulses to and receiving MR signals from a body(7) of a patient positioned in an examination volume (2), the RF antennas (9) having spatial transmit and receive sensitivity profiles. The apparatus is arranged to: -control the temporal succession, the phase, and the amplitude of the RF feeding of each individual RF antenna (9), the phases and amplitudes being determined from the spatial transmit sensitivity profiles of the RF antennas(9), and -reconstruct a MR image from a combination of the received MR signals received via the individual RF antennas(9) and from the spatial receive sensitivity profiles of the RF antennas(9). The invention proposes that the apparatus is further arranged to: -determine the spatial transmit sensitivity profiles of the RF antennas (9) from the spatial receive sensitivity profiles of the RF antennas (9), or -determine the spatial receive sensitivity profiles of the RF antennas (9) from the spatial transmit sensitivity profiles of the RF antennas (9).
摘要翻译：磁共振成像装置技术领域本发明涉及一种磁共振成像设备，其包括用于将RF脉冲发射到患者身体（7）并从患者身体（7）接收MR信号的两个或更多个RF天线（9）的阵列，检查体积（2），所述RF天线（9）具有空间发射和接收灵敏度分布。该设备被布置为： - 控制每个单独的RF天线（9）的RF馈送的时间顺序，相位和幅度，相位和幅度根据RF天线（9）的空间发射灵敏度曲线确定，并且 - 从经由各个RF天线（9）接收到的MR信号的组合以及从RF天线（9）的空间接收灵敏度简档中重建MR图像。本发明提出，该设备还被布置为： - 根据RF天线（9）的空间接收灵敏度分布来确定RF天线（9）的空间发射灵敏度分布，或者 - 确定RF 天线（9）与RF天线（9）的空间发射灵敏度分布相匹配。

2. 发明申请

WO2011086477A1 THERAPEUTIC APPARATUS 审中-公开
标题翻译：治疗设备
公开(公告)号：WO2011086477A1
公开(公告)日：2011-07-21
申请号：PCT/IB2011/050038
申请日：2011-01-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KATSCHER, Ulrich , LIPS, Oliver , FINDEKLEE, Christian , LEUSSLER, Christoph , NEHRKE, Kay , WIRTZ, Daniel , OVERWEG, Johannes, Adrianus
发明人： KATSCHER, Ulrich , LIPS, Oliver , FINDEKLEE, Christian , LEUSSLER, Christoph , NEHRKE, Kay , WIRTZ, Daniel , OVERWEG, Johannes, Adrianus
IPC分类号： A61N7/02 , A61N1/40 , A61N5/10 , A61B17/00 , A61B19/00
CPC分类号： A61N5/1064 , A61B2017/00084 , A61B2090/374 , A61N1/403 , A61N5/10 , A61N5/1084 , A61N7/00 , A61N7/02 , A61N2005/007 , A61N2005/1055 , G01R33/4804 , G01R33/4808
摘要： The invention provides for a therapeutic apparatus comprising a tissue heating system (302, 480, 482). The therapeutic apparatus further comprises a magnetic resonance imaging system (300) for acquiring magnetic resonance thermometry data (366) from nuclei of a subject (318) located within an imaging volume (330). The therapeutic apparatus further comprises a radiation therapy system (304, 592) for irradiating an irradiation volume (316, 516) of the subject, wherein the irradiation volume is within the imaging volume. The therapeutic apparatus further comprises a controller (354) for controlling the therapeutic apparatus. The controller is adapted for acquiring (100, 210) magnetic resonance thermometry data repeatedly using the magnetic resonance imaging system. The controller is adapted for heating (102, 208) at least the irradiation volume using the tissue heating system. The heating is controlled using the magnetic resonance thermometry data. The controller is adapted for irradiating (104, 208) the irradiation volume.
摘要翻译：本发明提供一种包括组织加热系统（302,480,482）的治疗设备。治疗装置还包括用于从位于成像体积（330）内的对象（318）的核获取磁共振测温数据（366）的磁共振成像系统（300）。治疗装置还包括用于照射受试者的照射体积（316,516）的放射治疗系统（304,592），其中照射体积在成像体积内。治疗装置还包括用于控制治疗仪的控制器（354）。控制器适于使用磁共振成像系统重复地获取（100,210）磁共振测温数据。控制器适于使用组织加热系统加热（102,208）至少照射体积。使用磁共振测温数据来控制加热。控制器适于照射（104,208）照射体积。

3. 发明申请

WO2009118702A3 FLIP ANGLE IMAGING WITH IMPROVED B1 MAPPING FOR MULTI-RF TRANSMIT SYSTEMS 审中-公开
公开(公告)号：WO2009118702A3
公开(公告)日：2009-10-01
申请号：PCT/IB2009/051258
申请日：2009-03-26
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , NEHRKE, Kay , BOERNERT, Peter , VOIGT, Tobias Ratko , KATSCHER, Ulrich
发明人： NEHRKE, Kay , BOERNERT, Peter , VOIGT, Tobias Ratko , KATSCHER, Ulrich
IPC分类号： G01R33/3415 , G01R33/565
摘要： A magnetic resonance method includes performing a plurality of magnetic resonance excitation operations each using a different sub-set of a set of radio frequency transmit coils (30), each sub-set including more than one radio frequency transmit coil, acquiring magnetic resonance data responsive to each said magnetic resonance excitation operation, and computing a B1 or flip angle map for each radio frequency transmit coil of the set of radio frequency transmit coils based on the acquired magnetic resonance data. A magnetic resonance method includes performing an actual flip angle mapping (AFI) sequence using a radio frequency transmit coil (32) with a ratio TR 1 : TR 2 of the TR times of the AFI sequence selected to be rational, acquiring magnetic resonance data responsive to said AFI sequence, and computing a B1 or flip angle map for the radio frequency transmit coil based on the acquired magnetic resonance data.

4. 发明申请

WO2010032172A1 B1-MAPPING AND B1L-SHIMMING FOR MRI 审中-公开
标题翻译：用于MRI的B1映射和B1L-SHIMMING
公开(公告)号：WO2010032172A1
公开(公告)日：2010-03-25
申请号：PCT/IB2009/053956
申请日：2009-09-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BOERNERT, Peter , KOKEN, Peter , NEHRKE, Kay , KATSCHER, Ulrich , GRAESSLIN, Ingmar
发明人： BOERNERT, Peter , KOKEN, Peter , NEHRKE, Kay , KATSCHER, Ulrich , GRAESSLIN, Ingmar
IPC分类号： G01R33/3415 , G01R33/58
CPC分类号： G01R33/583 , G01R33/246 , G01R33/3415 , G01R33/4838 , G01R33/5612 , G01R33/5659 , G01R33/586
摘要： The invention relates to a method of acquiring MRI image data comprising the following steps: performing a 3 -dimensional Bl mapping of a first volume using a first voxel size, selecting an MRI protocol, performing the Bl -shim in accordance with the MRI protocol, performing the MRI protocol to acquire MRI imaging data of a second volume using a second voxel size, wherein the first voxel size is larger than the second voxel size, wherein the first volume is larger than the second volume, and wherein the second volume is contained within the first volume.
摘要翻译：本发明涉及一种获取MRI图像数据的方法，包括以下步骤：使用第一体素大小执行第一体积的3维B1映射，选择MRI协议，根据MRI协议执行Bl-shim，执行MRI协议以使用第二体素尺寸获取第二体积的MRI成像数据，其中所述第一体素大小大于所述第二体素大小，其中所述第一体积大于所述第二体积，并且其中所述第二体积被包含在第一卷内。

5. 发明申请

WO2010113131A1 SAR REDUCTION IN PARALLEL TRANSMISSION BY K-SPACE DEPENDENT RF PULSE SELECTION 审中-公开
标题翻译：通过K空间依赖射频脉冲选择并行传输的SAR减少
公开(公告)号：WO2010113131A1
公开(公告)日：2010-10-07
申请号：PCT/IB2010/051423
申请日：2010-04-01
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BOERNERT, Peter , GRAESSLIN, Ingmar , NEHRKE, Kay
发明人： BOERNERT, Peter , GRAESSLIN, Ingmar , NEHRKE, Kay
IPC分类号： G01R33/3415
CPC分类号： G01R33/3415 , G01R33/288 , G01R33/543 , G01R33/5612 , G01R33/5659
摘要： When generating an MR image using a multi-channel transmit coil arrangement, SAR is reduced by employing a number of different RF pulses in a single scan. Each RF pulse exhibits a different performance and/or accuracy, resulting in different RF pulse- specific SAR values. As a result, the RF pulses differ slightly in actual excitation pattern, B1 waveform and/or k-space trajectory, etc. The average SAR over a single scan is thus reduced compared to a fixed RF pulse, without compromising image quality.
摘要翻译：当使用多通道发射线圈装置产生MR图像时，通过在单次扫描中采用多个不同的RF脉冲来减小SAR。每个RF脉冲表现出不同的性能和/或精度，导致不同的RF脉冲特定SAR值。结果，RF脉冲在实际激励模式，B1波形和/或k空间轨迹等方面略有差异。与固定的RF脉冲相比，单次扫描的平均SAR相比降低，而不影响图像质量。

6. 发明申请

WO2008132659A2 MAGNETIC RESONANCE DEVICE AND METHOD 审中-公开
标题翻译：磁共振装置及方法
公开(公告)号：WO2008132659A2
公开(公告)日：2008-11-06
申请号：PCT/IB2008/051544
申请日：2008-04-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , EGGERS, Holger , NEHRKE, Kay , BOERNERT, Peter
发明人： EGGERS, Holger , NEHRKE, Kay , BOERNERT, Peter
IPC分类号： G01R33/561
CPC分类号： G01R33/4824 , G01R33/4826 , G01R33/4835 , G01R33/561 , G01R33/5615 , G01R33/5617 , G01R33/56509 , G01R33/5676
摘要： The invention relates to a device for MRI of a body (7) placed in an examination volume. The device (1) comprises means (2) for establishing a substantially homogeneous main magnetic field in the examination volume, means (3, 4, 5) for generating switched magnetic field gradients superimposed upon the main magnetic field, means (6) for radiating RF pulses towards the body (7), control means (12) for controlling the generation of the magnetic field gradients and the RF pulses, means (10) for receiving and sampling MR signals, and reconstruction means (14) for forming MR images from the signal samples. According to one aspect of the invention, the device (1) is arranged to acquire a plurality of k-space blades according to the PROPELLER scheme, the k-space blades being rotated about a center of k-space, wherein the rotation angle of the k-space blades is incremented during MR signal acquisition by the Golden Angle (or by the half Golden Angle). According to another aspect of the invention, the device (1) is arranged to acquire an MR reference data set from a central portion of k-space prior to a multi-slice PROPELLER acquisition. According to still another aspect of the invention, the device (1) is arranged to weight the acquired MR data, wherein weighting factors are computed on the basis of acquisition times for contrast manipulation, correlation measures for motion compensation, and on the basis of the geometry of the overlapping areas of the k-space blades.
摘要翻译：本发明涉及放置在检查体积中的身体（7）的MRI装置。装置（1）包括用于在检查体积中建立基本均匀的主磁场的装置（2），用于产生叠加在主磁场上的开关磁场梯度的装置（3,4,5），用于辐射的装置（6）朝向身体的射频脉冲（7），用于控制磁场梯度和RF脉冲的产生的控制装置（12），用于接收和采样MR信号的装置（10），以及用于形成MR图像的重建装置（14）信号样本。根据本发明的一个方面，装置（1）被布置为根据PROPELLER方案获取多个k空间叶片，k空间叶片围绕k空间的中心旋转，其中旋转角度在MR信号采集期间，通过金角（或黄金角度），k空间叶片增加。根据本发明的另一方面，设备（1）被布置成在多层螺旋桨获取之前从k空间的中心部分获取MR参考数据集。根据本发明的另一方面，所述装置（1）被配置为对所获取的MR数据进行加权，其中基于对比度操作的获取时间，运动补偿的相关度量，以及基于 k空间叶片重叠区域的几何形状。

7. 发明申请

WO2012140536A1 MR IMAGING WITH B1MAPPING 审中-公开
标题翻译：拍摄与拍摄
公开(公告)号：WO2012140536A1
公开(公告)日：2012-10-18
申请号：PCT/IB2012/051590
申请日：2012-04-02
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , VAN DER MEULEN, Peter , BOERNERT, Peter , NEHRKE, Kay
发明人： VAN DER MEULEN, Peter , BOERNERT, Peter , NEHRKE, Kay
IPC分类号： G01R33/24
CPC分类号： G01R33/288 , G01R33/246
摘要： The invention relates to a method of MR imaging, wherein a portion of a body is subjected to an imaging sequence of RF pulses and switched magnetic field gradients, which imaging sequence is a stimulated echo sequence including an off-resonant Bloch- Siegert RF pulse (BS) radiated during a preparation period (21) of the stimulated echo sequence. A B 1 map is derived from the acquired stimulated echo MR signals. Moreover, the invention relates to a method of MR imaging, wherein a portion of a body is subjected to a first imaging sequence, which comprises a first composite excitation RF pulse consisting of two RF pulse components having essentially equal flip angles and being out of phase by essentially 90°. Further, the portion of the body is subjected to a second imaging sequence, wherein a B 1 map is derived from signal data acquired by means of the first and second imaging sequences.
摘要翻译：本发明涉及一种MR成像方法，其中身体的一部分经受RF脉冲和切换磁场梯度的成像序列，该成像序列是受激回波序列，其包括非共振Bloch-Siegert RF脉冲（ BS）在刺激回波序列的准备阶段（21）期间辐射。从获得的受激回波MR信号导出B1图。此外，本发明涉及一种MR成像方法，其中身体的一部分经受第一成像序列，该第一成像序列包括第一复合激励RF脉冲，该第一复合激励RF脉冲由具有基本相等的翻转角并且相位不同的两个RF脉冲分量组成基本上为90°。此外，身体的部分经受第二成像序列，其中从通过第一和第二成像序列获取的信号数据导出B1图。

8. 发明申请

WO2010113062A1 ACCELERATED B1 MAPPING 审中-公开
标题翻译：加速B1映射
公开(公告)号：WO2010113062A1
公开(公告)日：2010-10-07
申请号：PCT/IB2010/051225
申请日：2010-03-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BOERNERT, Peter , NEHRKE, Kay
发明人： BOERNERT, Peter , NEHRKE, Kay
IPC分类号： G01R33/32 , G01R33/58
CPC分类号： G01R33/5612 , G01R33/246 , G01R33/5659 , G01R33/583 , G01R33/586
摘要： A method comprises: performing a number of B i field mapping sequences (24) using a set of radio frequency transmit coils (11) to acquire a B 1 field mapping data set wherein said number is less than a number of radio frequency transmit coils in the set of radio frequency transmit coils; and determining coil sensitivities (30) for the set of radio frequency transmit coils based on the acquired B1 field mapping data set. In some embodiments, the performed B 1 field mapping sequences are defined by (i) performing a linear transform (40) on the set of radio frequency transmit coils to generate a set of orthogonal virtual radio frequency transmit coils (42) and (ii) selecting (44) a sub- set (46) of the set of orthogonal virtual radio frequency transmit coils that define the performed B 1 field mapping sequences.
摘要翻译：一种方法包括：使用一组射频发射线圈（11）来执行多个B i场映射序列（24），以获取B1场映射数据集，其中所述数小于所述射频发射线圈的数量射频发射线圈组; 以及基于所获取的B1场映射数据集来确定所述一组射频发射线圈的线圈灵敏度（30）。在一些实施例中，所执行的B1场映射序列由（i）在射频发射线圈组上执行线性变换（40）来定义，以产生一组正交虚拟射频发射线圈（42）和（ii）选择（44）定义所执行的B1场映射序列的正交虚拟射频发射线圈组的子集（46）。

9. 发明申请

WO2012127341A1 COMPRESSED SENSING MR IMAGE RECONSTRUCTION USING CONSTRAINT FROM PRIOR ACQUISITION 审中-公开
标题翻译：使用来自先前收购的约束的压缩感测MR图像重建
公开(公告)号：WO2012127341A1
公开(公告)日：2012-09-27
申请号：PCT/IB2012/050930
申请日：2012-02-28
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , DONEVA, Mariya Ivanova , REMMELE, Stefanie , BÖRNERT, Peter , MAZURKEWITZ, Peter , SENEGAS, Julien , KEUPP, Jochen , NEHRKE, Kay
发明人： DONEVA, Mariya Ivanova , REMMELE, Stefanie , BÖRNERT, Peter , MAZURKEWITZ, Peter , SENEGAS, Julien , KEUPP, Jochen , NEHRKE, Kay
IPC分类号： G01R33/56 , G01R33/561 , G01R33/567 , G01R33/48
CPC分类号： G01R33/56 , G01R33/4824 , G01R33/5608 , G01R33/5611 , G01R33/56509
摘要： The invention relates to a method of MR imaging of at least a portion of a body (10) of a patient placed in an examination volume of a MR device (1), the method comprising the steps of: - subjecting the portion of the body(10) to a first imaging sequence for acquiring a first signal data set (21); - subjecting the portion of the body (10) to a second imaging sequence for acquiring a second signal data set (23), wherein the imaging parameters of the second imaging sequence differ from the imaging parameters of the first imaging sequence; - reconstructing a MR image from the second signal data set (23) by means of regularization using the first signal data set (21) as prior information. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).
摘要翻译：本发明涉及放置在MR装置（1）的检查体积中的患者的身体（10）的至少一部分的MR成像方法，该方法包括以下步骤： - 对身体的部分（10）到用于获取第一信号数据集（21）的第一成像序列; - 将所述身体（10）的所述部分经受第二成像序列以获取第二信号数据集（23），其中所述第二成像序列的成像参数与所述第一成像序列的成像参数不同; - 通过使用第一信号数据集（21）的正则化作为先验信息，从第二信号数据集（23）重建MR图像。此外，本发明涉及MR设备（1）和用于MR设备（1）的计算机程序。

10. 发明申请

WO2012023098A1 VIRTUAL COIL EMULATION IN PARALLEL TRANSMISSION MRI 审中-公开
标题翻译：平行传输中的虚拟线圈仿真MRI
公开(公告)号：WO2012023098A1
公开(公告)日：2012-02-23
申请号：PCT/IB2011/053611
申请日：2011-08-15
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , NEHRKE, Kay , BOERNERT, Peter
发明人： NEHRKE, Kay , BOERNERT, Peter
IPC分类号： G01R33/561
CPC分类号： G01R33/543 , G01R33/5612 , G01R33/5659
摘要： The invention relates to a virtual coil emulation method to be used in a magnetic resonance imaging scan for acquiring a magnetic resonance image of an object (10), wherein the scan is performed by an MR system (1) using a physical coil arrangement (9; 11; 12; 13) comprising set of individual transmit coils, the coils being adapted for transmission of a desired RF transmit field to the object (10) for magnetic resonance spin excitation of the object (10), wherein each coil is associated with a physical transmit channel, wherein the RF transmit field corresponds to a virtual arrangement of two or more of said coils, wherein virtual transmit channel properties comprising virtual transmit channel weights are assigned to the RF transmit field, said virtual transmit channel weights describing the virtual complex RF field amplitudes with respect to each individual coil of the virtual coil arrangement required to be applied to the physical coils (9; 11; 12; 13) for generating the RF transmit field.
摘要翻译：本发明涉及一种用于获取物体（10）的磁共振图像的磁共振成像扫描中的虚拟线圈仿真方法，其中，使用物理线圈装置（9）的MR系统（1）执行扫描 ; 11; 12; 13）包括一组单独的发射线圈，所述线圈适于将所需的RF发射场传输到所述物体（10），用于所述物体（10）的磁共振旋转激发，其中每个线圈与物理发射信道，其中RF发送字段对应于两个或更多个所述线圈的虚拟布置，其中包括虚拟发送信道权重的虚拟发送信道属性被分配给RF发送字段，所述虚拟发送信道权重描述虚拟复合体相对于虚拟线圈布置的每个单独线圈的RF场振幅需要施加到用于产生RF发射的物理线圈（9; 11; 12; 13）领域。

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