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1. 发明申请

WO2004077125A3 IMPROVEMENTS IN AND RELATING TO FLUID FILLED DEVICES 审中-公开
公开(公告)号：WO2004077125A3
公开(公告)日：2004-09-10
申请号：PCT/IB2004/050133
申请日：2004-02-19
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , KUIPER, Stein , VISSER, Derk
发明人： KUIPER, Stein , VISSER, Derk
IPC分类号： G02B26/02 , G02B3/14
摘要： A device (100; 200; 300; 400) comprising a sealed cavity (210) containing n volumes of fluids (80, 87; 220, 230; 320, 332; 420, 422, 430, 432) is described, where n is an integer and n>_2. Each volume of fluid is substantially immiscible with every contiguous volume of fluid. The cavity is defined by an interior surface divided into n continuous areas (60, 170; 260, 270; 360, 362, 370; 460, 462, 470, 472), each continuous area corresponding to and being in contact with a respective one of the volumes of fluid. The wettability of each area is such that each volume of fluid preferentially adheres to the corresponding continuous area rather than any one of the continuous areas adjacent to the corresponding area.

2. 发明申请

WO2010004493A1 AN OPTICAL IMAGE PROBE 审中-公开
标题翻译：光学图像探测器
公开(公告)号：WO2010004493A1
公开(公告)日：2010-01-14
申请号：PCT/IB2009/052900
申请日：2009-07-03
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , KUIPER, Stein , HENDRIKS, Bernardus, H., W. , MIHAJLOVIC, Nenad
发明人： KUIPER, Stein , HENDRIKS, Bernardus, H., W. , MIHAJLOVIC, Nenad
IPC分类号： G02B3/14 , G02B23/24
CPC分类号： G02B23/2438 , A61B1/0019 , G02B3/14
摘要： The invention relates to an optical image probe(20) for particularly suited for miniature application e.g. in-vivo. A fluid lens(5) is positioned a housing (19),the fluid lens having a changeable optical power. An image collector (40) is positioned within the housing, the collector being arranged on an optical path of the fluid lens, the collector being displaceable along the said optical path by an actuator (42, 70, 80, 90) in various ways. It is highly advantageous in obtaining a compact optical image probe and which simultaneously has a high zoom factor. Due the possible displacement of the image collector and the changeable optical power of the fluid lens, and cooperation between these two elements, it is possible to obtain a compact endoscope with a wide dynamic range of zoom factor with satisfactory focusing properties.
摘要翻译：本发明涉及一种特别适用于微型应用的光学图像探针（20）。被检体内。液体透镜（5）定位在壳体（19）上，流体透镜具有可变光学功率。图像收集器（40）定位在壳体内，集电器布置在流体透镜的光路上，集电器可以通过致动器（42,70,80,90）以各种方式沿着所述光路移动。在获得紧凑型光学图像探针并且同时具有高变焦系数方面是非常有利的。由于图像收集器的可能位移和流体透镜的可变光学功率以及这两个元件之间的协调，可以获得具有良好聚焦性能的宽动态范围的变焦系数的紧凑型内窥镜。

3. 发明申请

WO2009001300A1 LENS SYSTEM 审中-公开
标题翻译：镜头系统
公开(公告)号：WO2009001300A1
公开(公告)日：2008-12-31
申请号：PCT/IB2008/052532
申请日：2008-06-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , HENDRIKS, Bernardus Hendrikus Wilhelmus , SHIMIZU, Jeff , KUIPER, Stein
发明人： HENDRIKS, Bernardus Hendrikus Wilhelmus , SHIMIZU, Jeff , KUIPER, Stein
IPC分类号： G02B23/24
CPC分类号： G02B23/243 , G02B26/103
摘要： A lens system comprises a first lens group and a second lens group, and is configured to form an image at a first magnification and at a second magnification. The lens system has a common optical axis in both magnifications. The lens system is further configured to form an intermediate image between the first lens group and the second lens group at the first magnification. The intermediate image formed in the first magnification is further imaged onto an optical detector. In the first magnification, the second lens group acts as a relay lens imaging the intermediate image onto the optical detector. In the second magnification, the first and second lens groups together form an image on the optical detector without forming an intermediate image.
摘要翻译：透镜系统包括第一透镜组和第二透镜组，并且被配置为以第一放大率和第二放大率形成图像。透镜系统具有两个放大倍率的共同光轴。透镜系统还被配置为在第一放大率下在第一透镜组和第二透镜组之间形成中间图像。在第一放大率中形成的中间图像进一步成像到光学检测器上。在第一放大率中，第二透镜组用作将中间图像成像到中间透镜到光学检测器上。在第二放大倍数中，第一和第二透镜组一起在光学检测器上形成图像，而不形成中间图像。

4. 发明申请

WO2008023310A2 A METHOD AND SYSTEM FOR DETERMINING PROPERTIES OF BIOLOGICAL CELLS 审中-公开
标题翻译：用于确定生物细胞特性的方法和系统
公开(公告)号：WO2008023310A2
公开(公告)日：2008-02-28
申请号：PCT/IB2007/053283
申请日：2007-08-17
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , KUIPER, Stein , DEN TOONDER, Jacob, M., J.
发明人： KUIPER, Stein , DEN TOONDER, Jacob, M., J.
IPC分类号： G01N15/02
CPC分类号： G01N33/5026 , C12Q1/04 , C12Q1/24 , G01N15/0227
摘要： A system (100) for determining properties of particles is described, wherein elastic properties of particles can be studied. The system (100) typically comprises a microporous structure (110) having a first side and a second side, the microporous structure comprising a plurality of micropores extending from the first side to the second side. Using a means (120) for generating a pressure difference over the microporous structure, particles provided to the first side of the micropores (113) are passed at least partially into the micropores and deformed. A detector (130) is provided for qualitatively and/or quantitatively detecting presence of particles having passed at least partially into the micropores (113), thus allowing to obtain information about the deformation of the particles.
摘要翻译：描述了用于确定颗粒性质的系统（100），其中可以研究颗粒的弹性特性。系统（100）通常包括具有第一侧和第二侧的微孔结构（110），所述微孔结构包括从第一侧延伸到第二侧的多个微孔。使用用于在微孔结构上产生压力差的装置（120），提供到微孔（113）的第一侧的颗粒至少部分地进入微孔并变形。提供了一种检测器（130），用于定性和/或定量地检测已经至少部分地进入微孔（113）的颗粒的存在，从而允许获得关于颗粒变形的信息。

5. 发明申请

WO2008017967A1 DEVICE, SYSTEM AND METHOD FOR INTERACTING WITH A CELL OR TISSUE IN A BODY 审中-公开
标题翻译：用于与身体中的细胞或组织相互作用的装置，系统和方法
公开(公告)号：WO2008017967A1
公开(公告)日：2008-02-14
申请号：PCT/IB2007/051326
申请日：2007-04-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , ZOU, Hans , KUIPER, Stein , HENDRIKS, Bernardus Hendrikus Wilhelmus , SUIJVER, Jan Frederik , PIERIK, Anke , RENSEN, Judith Margreet , DIJKSMAN, Johan Frederik , SHIMIZU, Jeff , DEN TOONDER, Jacob Marinus Jan
发明人： ZOU, Hans , KUIPER, Stein , HENDRIKS, Bernardus Hendrikus Wilhelmus , SUIJVER, Jan Frederik , PIERIK, Anke , RENSEN, Judith Margreet , DIJKSMAN, Johan Frederik , SHIMIZU, Jeff , DEN TOONDER, Jacob Marinus Jan
IPC分类号： A61B5/00
CPC分类号： A61B5/6882 , A61B1/041 , A61B5/0031 , A61B5/073 , A61B5/4839
摘要： A device or support, system and method are provided for precisely targeted and/or highly controlled interaction with a targeted cell or tissue in a body, with the support providing an ergonomic connecting interface for selectively connecting the support to a cell or tissue with at least minimal adverse affect to such cell or tissue, the system providing a remote facility that may be operatively associated with the support, and the method providing steps for employing the support and/or system so as to, inter alia, improve treatment, diagnostic and/or monitoring techniques and increase sensitivity and specificity with respect to interacting with, for example, diseased or abnormal cells or tissue without adversely effecting surrounding healthy cells or tissue, and/or the body in general.
摘要翻译：提供了一种装置或支撑件，系统和方法，用于与身体中的靶细胞或组织精确地靶向和/或高度受控的相互作用，其中所述支持物提供符合人体工程学的连接界面，用于至少选择性地将支持物连接到细胞或组织对这种细胞或组织的最小的不利影响，该系统提供可能与支持物可操作地相关联的远程设施，以及提供使用支持和/或系统的方法，以便除其他外改善治疗，诊断和/ 或监测技术，并提高与例如患病或异常细胞或组织的相互作用的灵敏度和特异性，而不会不利地影响周围的健康细胞或组织和/或身体。

6. 发明申请

WO2006035362A3 SERVO BRANCH OF OPTICAL DISC DRIVE COMPRISING A SWITCHABLE DIAPHRAGM AND A DEVICE FOR BEAM DEFLECTION, AND METHODS FOR MEASURING BEAM LANDING AND SPHERICAL ABERRATION 审中-公开
公开(公告)号：WO2006035362A3
公开(公告)日：2006-04-06
申请号：PCT/IB2005/053092
申请日：2005-09-20
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , STALLINGA, Sjoerd , HENDRIKS, Bernardus, H., W. , TUKKER, Teus , KUIPER, Stein , IMMINK, Albert, H., J. , LIEDENBAUM, Coen, T., H., F.
发明人： STALLINGA, Sjoerd , HENDRIKS, Bernardus, H., W. , TUKKER, Teus , KUIPER, Stein , IMMINK, Albert, H., J. , LIEDENBAUM, Coen, T., H., F.
IPC分类号： G11B7/00
摘要： A switchable diaphragm (9) and a device for beam deflection (10) are placed in the servo branch of an optical drive, in a path of light beams of different diffraction orders. This permits redirection of light beam orders towards a detection means (8) on an individual basis and selection of light orders at a detection means (8) depending on requirements. The number of detectors in the device detection means (8) can thus be reduced, thereby also reducing additional components associated with those detectors and saving on cost and complexity. With such device functionality, new methods for measuring beam landing and spherical aberration are developed.

7. 发明申请

WO2005122139A2 ACOUSTIC DEVICE WITH VARIABLE FOCAL LENGTH 审中-公开
标题翻译：具有可变焦距的声学设备
公开(公告)号：WO2005122139A2
公开(公告)日：2005-12-22
申请号：PCT/IB2005/051813
申请日：2005-06-03
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , KUIPER, Stein , HENDRIKS, Bernardus
发明人： KUIPER, Stein , HENDRIKS, Bernardus
IPC分类号： G10K11/30
CPC分类号： G10K11/30
摘要： A device comprises an acoustic lens (100) with a variable focal length and means (12) for directing incoming acoustic waves onto the lens. The acoustic lens comprises a curved boundary between two fluid media (1, 2) in which the acoustic waves have different propagation velocities. Means (5, 6, 7) are provided for applying a force directly onto one of the fluid media (1) so as to induce a displacement of the boundary (M1, M2). Such arrangement of the acoustic lens makes it possible to achieve rapid variations in the focal length.
摘要翻译：装置包括具有可变焦距的声透镜（100）和用于将入射的声波引导到透镜上的装置（12）。声透镜包括两个流体介质（1,2）之间的弯曲边界，其中声波具有不同的传播速度。提供装置（5,6,7）用于将力直接施加到一个流体介质（1）上，以便引起边界（M1，M2）的位移。声透镜的这种布置使得可以实现焦距的快速变化。

8. 发明申请

WO2005119306A1 OPTICAL ELEMENT 审中-公开
标题翻译：光学元件
公开(公告)号：WO2005119306A1
公开(公告)日：2005-12-15
申请号：PCT/IB2005/051738
申请日：2005-05-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , KUIPER, Stein , HENDRIKS, Bernardus, H., W. , VAN DER AA, Michiel, J., M. , SCHLEIPEN, Johannes, J., H., B. , VAN SANTEN, Helmar
发明人： KUIPER, Stein , HENDRIKS, Bernardus, H., W. , VAN DER AA, Michiel, J., M. , SCHLEIPEN, Johannes, J., H., B. , VAN SANTEN, Helmar
IPC分类号： G02B3/14
CPC分类号： G02B3/14 , G02B26/004
摘要： An optical element comprises a fluid chamber, the fluid chamber having side and end walls, and contains a first fluid (20) and a second fluid (22). The fluids are non-miscible and the second fluid is capable of being influenced by a magnetic field. A device (19) for providing a magnetic field over at least a portion of the fluid chamber is provided, with the magnetic field being capable of moving the second fluid so that the positions of the first an second fluids in the fluid chamber are altered. The second fluid may be a ferrofluid.
摘要翻译：光学元件包括流体室，流体室具有侧壁和端壁，并且包含第一流体（20）和第二流体（22）。流体是不可混溶的，并且第二流体能够受到磁场的影响。提供了用于在流体室的至少一部分上提供磁场的装置（19），其中磁场能够移动第二流体，使得流体室中的第一流体的位置被改变。第二流体可以是铁磁流体。

9. 发明申请

WO2005096035A1 CONTROLLABLE OPTICAL LENS 审中-公开
标题翻译：可控光学镜头
公开(公告)号：WO2005096035A1
公开(公告)日：2005-10-13
申请号：PCT/IB2005/051055
申请日：2005-03-29
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , IMMINK, Albert, H., J. , HENDRIKS, Bernardus, H., W. , KUIPER, Stein , HELWEGEN, Ivon, F. , VAN AS, Marco, A., J.
发明人： IMMINK, Albert, H., J. , HENDRIKS, Bernardus, H., W. , KUIPER, Stein , HELWEGEN, Ivon, F. , VAN AS, Marco, A., J.
IPC分类号： G02B3/14
CPC分类号： G02B3/14 , G02B26/005 , Y10S359/90
摘要： A controllable optical lens system, comprises a chamber housing first and second fluids, the interface between the fluids defining a lens surface. An electrode arrangement controls the shape of the lens surface and has first and second electrodes. A parameter is determined by the system dependent on the electrical resistance through at least one of the lens fluids between the first and second electrodes. Thus, the series resistance through a lens fluid is used as a measure of meniscus position.
摘要翻译：可控光学透镜系统包括容纳第一和第二流体的腔室，流体之间的界面限定透镜表面。电极装置控制透镜表面的形状并具有第一和第二电极。取决于通过第一和第二电极之间的透镜流体中的至少一个的电阻，系统确定参数。因此，通过透镜流体的串联电阻被用作弯液面位置的量度。

10. 发明申请

WO2005096033A1 OPTICAL ELEMENT FOR CORRECTING REFRACTIVE INDEX RELATED ABBERATIONS 审中-公开
标题翻译：修正相关索引的光学元件
公开(公告)号：WO2005096033A1
公开(公告)日：2005-10-13
申请号：PCT/IB2005/051018
申请日：2005-03-24
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , HENDRIKS, Bernardus, H., W. , KUIPER, Stein
发明人： HENDRIKS, Bernardus, H., W. , KUIPER, Stein
IPC分类号： G02B3/14
CPC分类号： G02B3/14 , G02B26/005
摘要： An optical element (1) for correcting refractive index related aberrations comprises a fluid chamber (5) which is provided with an electrode configuration (2,12) and includes a first, electrically conducting, fluid (B) and a second, non-conducting, fluid (A), and an interface (14) between the fluids, the fluids having different Abbe numbers. By applying a voltage (VO to the electrode configuration electrowetting forces are generated, which deform the shape of the interface (14,14') and determine the corrective power.
摘要翻译：用于校正折射率相关像差的光学元件（1）包括流体室（5），其设置有电极构造（2,12），并且包括第一导电流体（B）和第二非导电，流体（A）和流体之间的界面（14），流体具有不同的阿贝数。通过施加电压（VO到电极配置产生电润湿力，其使接口（14,14'）的形状变形并确定校正功率。

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