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1. 发明申请

WO2010061339A1 DEVICE AND METHOD FOR OPTICALLY EXAMINING THE INTERIOR OF A TURBID MEDIUM 审中-公开
标题翻译：用于光学检查涡轮介质内部的装置和方法
公开(公告)号：WO2010061339A1
公开(公告)日：2010-06-03
申请号：PCT/IB2009/055329
申请日：2009-11-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , HARBERS, Rik , VAN BEEK, Michael, C. , RENSEN, Wouter, H., J.
发明人： HARBERS, Rik , VAN BEEK, Michael, C. , RENSEN, Wouter, H., J.
IPC分类号： A61B5/00
CPC分类号： A61B5/0059 , A61B5/4528 , A61B2562/146
摘要： A device for optically examining the interior of a turbid medium is provided. The device comprises: a light source unit (2) adapted to emit light for irradiating the turbid medium (5); a detector unit (6) adapted for detecting light emanating from the turbid medium (5); and a support (4) adapted for supporting the turbid medium during examination. The support comprises a support surface (3) against which the turbid medium rests during examination. The support surface (3) is provided with a deformable layer (9) of a light- blocking substance.
摘要翻译：提供了用于光学检查混浊介质内部的装置。该装置包括：适于发射光以照射混浊介质的光源单元（2）; 适于检测从混浊介质发出的光的检测器单元（6）; 以及适于在检查期间支撑混浊介质的支撑件（4）。支撑件包括支撑表面（3），混浊介质在检查期间搁置在支撑表面（3）上。支撑表面（3）设置有遮光物质的可变形层（9）。

2. 发明申请

WO2009147560A2 OPTICAL DETECTION METHOD AND DEVICE FOR OPTICAL DETECTION OF THE CONDITION OF JOINTS 审中-公开
标题翻译：光学检测方法和用于光学检测接头状态的装置
公开(公告)号：WO2009147560A2
公开(公告)日：2009-12-10
申请号：PCT/IB2009/052112
申请日：2009-05-20
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , RENSEN, Wouter, H., J. , VAN BEEK, Michael, C. , HARBERS, Rik
发明人： RENSEN, Wouter, H., J. , VAN BEEK, Michael, C. , HARBERS, Rik
IPC分类号： A61B5/00
CPC分类号： A61B5/0059 , A61B5/02007 , A61B5/4528 , A61B5/6826 , A61B5/6838
摘要： An optical detection method is provided, wherein a body part (5) comprising at least one joint (6) is irradiated with light. Local attenuation of the light by the body part (5) is detected as attenuation measurements at the position of the at least one joint (6) and at the position of at least one other portion of the body part (5); and wherein blood flow to and/or from the body part (5) is temporarily at least partially blocked and thereafter enabled again. Distinct local attenuation measurements for the at least one joint (6) and for at least one other portion of the body part (5) are performed for at least two of the times before (I), during (II), and after (III) the blocking of blood flow.
摘要翻译：提供了一种光学检测方法，其中包括至少一个接头（6）的主体部分（5）被照射。在身体部分（5）的光的局部衰减被检测为在至少一个关节（6）的位置处和身体部分（5）的至少另一部分的位置处的衰减测量; 并且其中进入和/或离开身体部分（5）的血液流动暂时至少部分被阻止，然后再次启动。对于至少一个关节（6）和身体部分（5）的至少一个其他部分的不同的局部衰减测量在（I），（II）之前和之后（III）的至少两个时间进行）堵塞血流。

3. 发明申请

WO2010038207A1 DEVICE FOR OPTICALLY EXAMINING THE INTERIOR OF A TURBID MEDIUM 审中-公开
标题翻译：用于光学检查涡轮介质内部的装置
公开(公告)号：WO2010038207A1
公开(公告)日：2010-04-08
申请号：PCT/IB2009/054292
申请日：2009-10-01
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , RENSEN, Wouter, H., J. , VAN BEEK, Michael, C. , HARBERS, Rik
发明人： RENSEN, Wouter, H., J. , VAN BEEK, Michael, C. , HARBERS, Rik
IPC分类号： A61B5/00
CPC分类号： A61B5/0059 , A61B5/4528 , A61B2562/146
摘要： A device for optically examining the interior of a turbid medium is provided. The device comprises a light source (3) adapted to emit light for irradiating the turbid medium; a detector unit (4) adapted for detecting light emanating from the turbid medium; and a light guide adapted for guiding light emitted by the light source to the turbid medium. The light guide comprises a support (10; 100) comprising a support surface (20; 120) for supporting the turbid medium to be examined and for coupling the light emitted by the light source (3) through the support surface (20; 120) into the turbid medium. The device is structured such that light from the light source (3) exits through the support surface (20; 120) only at positions at which the support surface is contacted.
摘要翻译：提供了用于光学检查混浊介质内部的装置。该装置包括适于发射光以照射混浊介质的光源（3）; 检测器单元（4），适于检测从混浊介质发出的光; 以及适于将由光源发射的光引导到混浊介质的光导。光引导件包括支撑件（10; 100），支撑件（20; 120）用于支撑待检查的混浊介质并且用于将由光源（3）发射的光通过支撑表面（20; 120）耦合，进入混浊介质。该装置的结构使得来自光源（3）的光仅在支撑表面接触的位置处通过支撑表面（20; 120）离开。

4. 发明申请

WO2010044029A1 IMAGING DEVICE AND METHOD 审中-公开
标题翻译：成像装置和方法
公开(公告)号：WO2010044029A1
公开(公告)日：2010-04-22
申请号：PCT/IB2009/054439
申请日：2009-10-09
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , HARBERS, Rik , VAN BEEK, Michael, C. , RENSEN, Wouter, H., J.
发明人： HARBERS, Rik , VAN BEEK, Michael, C. , RENSEN, Wouter, H., J.
IPC分类号： A61B19/08 , A61B19/00
CPC分类号： A61B46/17 , A61B46/10 , A61B90/05 , A61B2017/00907 , A61B2017/00915 , A61B2017/0092
摘要： The invention relates to the field of imaging an object, and, more specifically, to a method of imaging an object and to an imaging device comprising an imaging surface (14). A replaceable first foil section (18a) is arranged at an exposed position in front of the imaging surface (14), covering the imaging surface. Further foil sections (18) of a supply of foil sections are arranged to automatically get into an exposed position in front of the imaging surface (14) on removing a respective previous foil section (18a) from its exposed position in front of the imaging surface (14).
摘要翻译：本发明涉及对物体进行成像的领域，更具体地，涉及一种对物体和包括成像表面（14）的成像装置成像的方法。可替换的第一箔部分（18a）布置在成像表面（14）的前面的暴露位置，覆盖成像表面。箔片部分的进一步箔片部分（18）布置成在成像表面（14）的前方自动进入暴露位置，从而从成像表面前面的暴露位置移除相应的先前的箔片部分（18a）（14）。

5. 发明申请

WO2010044003A2 DEVICE AND METHOD FOR OPTICALLY EXAMINING THE INTERIOR OF A TURBID MEDIUM 审中-公开
标题翻译：用于光学检查涡轮介质内部的装置和方法
公开(公告)号：WO2010044003A2
公开(公告)日：2010-04-22
申请号：PCT/IB2009/054365
申请日：2009-10-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VAN BEEK, Michael, C. , RENSEN, Wouter, H., J. , HARBERS, Rik
发明人： VAN BEEK, Michael, C. , RENSEN, Wouter, H., J. , HARBERS, Rik
IPC分类号： G01N21/47 , G01N21/49 , G01N21/59 , A61B5/00
CPC分类号： A61B5/0059 , A61B5/4528 , G01N21/4795 , G01N2201/0626 , G01N2201/0635 , G01N2201/0675 , G01N2201/124
摘要： A device (1; 10; 20; 30; 40) for optically examining the interior of a turbid medium is provided. The device comprises an illumination system (2; 12; 22; 32; 42) adapted for illuminating a turbid medium to be examined and an imaging device (106) adapted for generating images from detected light. The illumination system (2; 12; 22; 32; 42) is adapted to be operable in at least a first mode in which a large area is illuminated and a second mode in which at least one selected region (110) of the large area is illuminated.
摘要翻译：提供了一种用于光学检查混浊介质内部的装置（1; 10; 20; 30; 40）。该装置包括适于照射要检查的混浊介质的照明系统（2; 12; 22; 32; 42）和适于从检测到的光产生图像的成像装置（106）。照明系统（2; 12; 22; 32; 42）适于在其中照亮大面积的至少第一模式和第二模式中操作，其中大面积的至少一个选定区域（110）被照亮。

6. 发明申请

WO2008068685A1 OBTAINING OPTICAL TISSUE PROPERTIES 审中-公开
标题翻译：获得光学组织特性
公开(公告)号：WO2008068685A1
公开(公告)日：2008-06-12
申请号：PCT/IB2007/054846
申请日：2007-11-29
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , HENDRIKS, Bernardus, H., W. , KUIPER, Stein , DE BOER, Ruth, W., I. , BRAUN, Augustinus, L. , VAN BEEK, Michael, C. , RENSEN, Wouter, H., J.
发明人： HENDRIKS, Bernardus, H., W. , KUIPER, Stein , DE BOER, Ruth, W., I. , BRAUN, Augustinus, L. , VAN BEEK, Michael, C. , RENSEN, Wouter, H., J.
IPC分类号： A61B5/00
CPC分类号： A61B5/0066 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/6848
摘要： This application describes a medical device (230) for obtaining optical tissue properties of a target material. The medical device (230) comprises an elongated body (231) having a longitudinal axis (232) and an optical fiber being integrated within the elongated body (231). The optical fiber has a second fiber end (242, 242a, 242b), which is arranged at a side wall (233) of the elongated body (231) and which provides a lateral field of view with respect to the longitudinal axis (232). According to an embodiment many optical fibers are integrated each having an optical outlet (242, 242a, 242b) around the elongated body (231). Using the outlets (242, 242a, 242b) to do diffuse optical tomography and also use optical fibers to do an optical inspection, one can get information on the presence of tumors in a volume around the medical device (230) and a tissue characterization in the vicinity of the medical device (230). Thereby, an optical biopsy may be carried out, wherein no real tissue is removed. According to another embodiment an optical detection system is integrated into a real biopsy needle (330) allowing inspection and taking real biopsy simultaneously.
摘要翻译：本申请描述了用于获得目标材料的光学组织性质的医疗装置（230）。医疗装置（230）包括具有纵向轴线（232）的细长主体（231）和整合在细长主体（231）内的光纤。光纤具有第二光纤端（242,242a，242b），其被布置在细长主体（231）的侧壁（233）处，并且相对于纵向轴线（232）提供横向视场，。根据实施例，许多光纤被集成为每个都具有围绕细长主体（231）的光学出口（242,242a，242b）。使用出口（242,242a，242b）进行漫射光学层析成像，并且还使用光纤进行光学检查，可以获得关于医疗装置周围的体积肿瘤的存在的信息（230）和组织表征医疗装置（230）的附近。因此，可以进行光学活检，其中不去除真实的组织。根据另一个实施例，光学检测系统被集成到实际的活检针（330）中，允许同时进行检查和进行实际的活检。

7. 发明申请

WO2004093669A1 CATHETER HEAD 审中-公开
标题翻译：导管头
公开(公告)号：WO2004093669A1
公开(公告)日：2004-11-04
申请号：PCT/IB2004/050498
申请日：2004-04-23
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VAN BEEK, Michael, C. , LIEDENBAUM, Coen, T., H., F. , LUCASSEN, Gerhardus, W. , RENSEN, Wouter, H., J.
发明人： VAN BEEK, Michael, C. , LIEDENBAUM, Coen, T., H., F. , LUCASSEN, Gerhardus, W. , RENSEN, Wouter, H., J.
IPC分类号： A61B5/00
CPC分类号： A61B5/14532 , A61B5/14542 , A61B5/14546 , A61B5/1459 , A61B6/481 , A61B6/504 , A61B2562/0238
摘要： The present invention relates to a catheter head comprising: means (104, 108; 306, 304; 320; 322; 326; 338) for directing of radiation to a blood detection volume (220; 310), means (104, 108; 306, 304; 320; 322; 326; 332, 334, 330; 338) for receiving of return radiation from the blood detection volume, means (104; 306; 330) for transmitting of the return radiation to means (122) for analysis of the return radiation for determination of at least one property of the blood.
摘要翻译：本发明涉及一种导管头，包括：用于将辐射引导到血液检测体积（220; 310）的装置（104,108; 306,304; 320; 322; 326; 338）用于从所述血液检测体积接收返回辐射的装置，用于将所述返回辐射传送到装置（122）的装置（104; 306; 330），用于分析用于确定血液的至少一种性质的返回辐射。

8. 发明申请

WO2004057285A1 OPTICAL ANALYSIS SYSTEM 审中-公开
标题翻译：光学分析系统
公开(公告)号：WO2004057285A1
公开(公告)日：2004-07-08
申请号：PCT/IB2003/006089
申请日：2003-12-19
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , SCHUURMANS, Frank, J., P. , VAN BEEK, Michael, C. , BAKKER, Levinus, P. , RENSEN, Wouter, H., J. , HENDRIKS, Bernardus, H., W. , HENDRIKS, Robert, F., M. , STEFFEN, Thomas
发明人： SCHUURMANS, Frank, J., P. , VAN BEEK, Michael, C. , BAKKER, Levinus, P. , RENSEN, Wouter, H., J. , HENDRIKS, Bernardus, H., W. , HENDRIKS, Robert, F., M. , STEFFEN, Thomas
IPC分类号： G01J3/28
CPC分类号： G01J3/02 , G01J3/0205 , G01J3/021 , G01J3/10 , G01J3/28 , G01J3/36 , G01N21/274 , G01N21/31 , G01N2021/3196 , G01N2201/129
摘要： The optical analysis system (20) for determining an amplitude of a principal component of an optical signal comprises a multivariate optical element (10) for reflecting the optical signal and thereby weighing the optical signal by a spectral weighing function, and a detector (9, 9P, 9N) for detecting the weighed optical signal. The optical analysis system (20) may further comprise a dispersive element (2) for spectrally dispersing the optical signal, the multivariate optical element being arranged to receive the dispersed optical signal. The blood analysis system (40) comprises the optical analysis system (20) according to the invention.
摘要翻译：用于确定光信号的主分量的幅度的光学分析系统（20）包括用于反射光信号并由此通过光谱称重功能称重光信号的多元光学元件（10） 9P，9N），用于检测加权的光信号。光学分析系统（20）还可以包括用于光谱分散光学信号的色散元件（2），所述多元光学元件被布置成接收分散的光信号。血液分析系统（40）包括根据本发明的光学分析系统（20）。

9. 发明申请

WO2008146198A3 DEVICE FOR IMAGING AN INTERIOR OF AN OPTICALLY TURBID MEDIUM USING DIFFUSE OPTICAL TOMOGRAPHY AND ULTRASOUND 审中-公开
公开(公告)号：WO2008146198A3
公开(公告)日：2008-12-04
申请号：PCT/IB2008/051992
申请日：2008-05-21
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , BAKKER, Levinus, P. , VAN DER MARK, Martinus, B. , VAN BEEK, Michael, C. , HARBERS, Rik , SUIJVER, Jan, F.
发明人： BAKKER, Levinus, P. , VAN DER MARK, Martinus, B. , VAN BEEK, Michael, C. , HARBERS, Rik , SUIJVER, Jan, F.
IPC分类号： A61B5/00 , A61B8/08
摘要： The invention relates to a device for imaging the interior of a volume of an object using diffuse optical tomography and ultrasound. According to the invention a volume in which the object is accommodated and into which optical and ultrasound signals are sent is bound by a wall structure comprising entrance and exit positions for both the optical and ultrasound signals. In this way, the object can be positioned relative to the wall structure resulting in a well-defined measurement geometry. The invention improves the comparability of scans of an object that have been made at different points in time as the positioning of the object in a first scan can be precisely reproduced in a further scan relative to the wall structure.

10. 发明申请

WO2009060370A3 METHOD AND DEVICE FOR IMAGING AN INTERIOR OF AN OPTICALLY TURBID MEDIUM 审中-公开
公开(公告)号：WO2009060370A3
公开(公告)日：2009-05-14
申请号：PCT/IB2008/054559
申请日：2008-11-03
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , BAKKER, Levinus, P. , VAN BEEK, Michael, C. , VAN DER MARK, Martinus, B.
发明人： BAKKER, Levinus, P. , VAN BEEK, Michael, C. , VAN DER MARK, Martinus, B.
IPC分类号： A61B5/00 , G01N21/64
摘要： The invention relates to a method and a device (30, 125) for imaging an interior of an optically turbid medium (40). Light from a light source (35) is coupled into the turbid medium (40). Detection light emanating from the turbid medium (40) as a result of coupling (5) light from the light source (35) into the turbid medium (40) is collected. A first characteristic and a second characteristic of collected detection light are measured simultaneously. Next, the ratio of a first linear combination of the measured characteristics and a second linear combination of the measured characteristics is taken based on the recognition that the noise in both linear combinations is correlated.

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