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1. 发明申请

WO2009125339A3 A CARRIER FOR OPTICAL DETECTION IN SMALL SAMPLE VOLUMES 审中-公开
公开(公告)号：WO2009125339A3
公开(公告)日：2009-10-15
申请号：PCT/IB2009/051454
申请日：2009-04-07
申请人： KONINKLIJKE PHILIPS ELECTRONICS N. V. , SCHLEIPEN, Johannes, J., H., B. , EVERS, Toon, H. , NIEUWENHUIS, Jeroen, H. , DITTMER, Wendy, U. , BRULS, Dominique, M. , PRINS, Menno, W., J. , NEIJZEN, Jacobus, H., M. , BOURQUIN, Yannyk, P., J.
发明人： SCHLEIPEN, Johannes, J., H., B. , EVERS, Toon, H. , NIEUWENHUIS, Jeroen, H. , DITTMER, Wendy, U. , BRULS, Dominique, M. , PRINS, Menno, W., J. , NEIJZEN, Jacobus, H., M. , BOURQUIN, Yannyk, P., J.
IPC分类号： G01N21/25 , G01N21/41
摘要： The invention relates to a carrier (11) and an apparatus (100) for optical detection in a sample (1) in a sample chamber (2). The carrier (11) comprises an optical structure (50) for refracting an input light beam (Ll) into the adjacent sample chamber (2) and for collecting an output light beam (L2) from light that originates in the sample chamber (2) from the input light beam. Preferably, the optical structure (50) comprises grooves in the surface (12) of the carrier (11) in which the input light beam is transmitted over a short distance through a sample. The optical structure (50) can also be used for a wetting detection.

2. 发明申请

WO2010049883A1 BIOSENSOR WITH MULTI-CHAMBER CARTRIDGE 审中-公开
标题翻译：生物传感器与多个盒子
公开(公告)号：WO2010049883A1
公开(公告)日：2010-05-06
申请号：PCT/IB2009/054740
申请日：2009-10-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , NEIJZEN, Jacobus, H., M. , WIMBERGER-FRIEDL, Reinhold , MAAS, Joost, H. , NIEUWENHUIS, Jeroen, H. , BRULS, Dominique, M. , IMMINK, Albert, H., J. , OVSYANKO, Mikhail, M.
发明人： NEIJZEN, Jacobus, H., M. , WIMBERGER-FRIEDL, Reinhold , MAAS, Joost, H. , NIEUWENHUIS, Jeroen, H. , BRULS, Dominique, M. , IMMINK, Albert, H., J. , OVSYANKO, Mikhail, M.
IPC分类号： G01N33/543 , G01N35/00 , G01R33/00
CPC分类号： G01N33/54326 , B01L3/502761 , B82Y25/00 , G01N27/745 , G01R33/093 , G01R33/1269
摘要： The present invention provides a biosensor comprising a cartridge for accommodating a fluid sample, the cartridge comprising at least two chambers, wherein each chamber comprises a sensor surface with one or more binding sites. The biosensor further comprises means for generating a magnetic field at the binding sites of the sensor surfaces of the at least two chambers. The biosensor also comprises means for detecting particles accumulated at/and or proximate the binding sites of the sensor surfaces of the at least two chambers. Therein, the magnetic field at the binding sites has a sufficiently large gradient to actuate magnetic label particles towards the binding sites.
摘要翻译：本发明提供了一种生物传感器，其包括用于容纳流体样品的盒，所述盒包括至少两个室，其中每个室包括具有一个或多个结合位点的传感器表面。生物传感器还包括用于在至少两个室的传感器表面的结合位置处产生磁场的装置。生物传感器还包括用于检测在至少两个室的传感器表面的结合位点处和/或附近堆积的颗粒的装置。其中，结合位点处的磁场具有足够大的梯度以朝向结合位点致动磁性标记颗粒。

3. 发明申请

WO2009060357A1 BIOSENSOR CARTRIDGE 审中-公开
公开(公告)号：WO2009060357A1
公开(公告)日：2009-05-14
申请号：PCT/IB2008/054513
申请日：2008-10-30
申请人： KONINKLIJKE PHILIPS ELECTRONICS N. V. , NEIJZEN, Jacobus, H., M.
发明人： NEIJZEN, Jacobus, H., M.
IPC分类号： G01N21/03 , G01N21/11 , G01N21/55 , B01L3/00 , G01N33/551
CPC分类号： G01N21/552 , B01L3/50273 , B01L2200/0647 , B01L2300/0636 , B01L2300/0654 , B01L2300/0816 , B01L2400/0406 , B01L2400/086 , G01N21/03 , G01N21/11 , G01N21/6428 , G01N21/6458 , G01N21/648 , G01N2021/0325 , G01N2021/0346
摘要： The present invention provides a cartridge comprising a sample input portion and a sensor portion, wherein said sensor portion comprises a sensor surface and a first microstructure adapted to provide a capillary force for transporting sample fluid from the sample input portion to the sensor portion, wherein said microstructure does not interfere with the sensor surface.
摘要翻译：本发明提供了一种包括样品输入部分和传感器部分的盒，其中所述传感器部分包括传感器表面和适于提供用于将样品流体从样品输入部分传送到传感器部分的毛细管力的第一微结构，其中所述微结构不会干扰传感器表面。

4. 发明申请

WO2006134528A2 OPTICAL RECORDING MEDIUM AND METHOD OF MANUFACTURING AN OPTICAL RECORDING MEDIUM 审中-公开
标题翻译：光学记录介质和制造光记录介质的方法
公开(公告)号：WO2006134528A2
公开(公告)日：2006-12-21
申请号：PCT/IB2006/051840
申请日：2006-06-09
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , BOAMFA, Marius, I. , NEIJZEN, Jacobus, H., M.
发明人： BOAMFA, Marius, I. , NEIJZEN, Jacobus, H., M.
IPC分类号： G11B7/24 , G11B7/26 , G11B7/007
CPC分类号： G11B7/24079 , G11B7/24035 , G11B7/261
摘要： The present invention relates to an optical recording medium (10) having a layer (12), the optical properties of which are changed upon projecting a light beam with a given spot (20) size onto a surface (14) of the layer for writing data onto the optical recording medium, wherein the surface comprises regions (16) of a first type and regions (18) of a second type, the optical-properties changing-behavior of the regions of the first type and of the regions of the second type are different, and the width of the regions of the second type perpendicular to a writing direction is smaller than the spot size. The present invention further relates to a method of manufacturing an optical recording medium.
摘要翻译：本发明涉及一种具有层（12）的光学记录介质（10），其光学特性在将具有给定点（20）尺寸的光束投影到写入层的表面（14）上时，其变化数据到光学记录介质上，其中表面包括第一类型的区域（16）和第二类型的区域（18），第一类型的区域和第二类型的区域的光学特性变化行为类型不同，垂直于书写方向的第二类型的区域的宽度小于点尺寸。本发明还涉及一种制造光记录介质的方法。

5. 发明申请

WO2005019365A2 NON-LEACHING ADHESIVE SYSTEM AND ITS USE IN A LIQUID IMMERSION OBJECTIVE 审中-公开
标题翻译：非浸出粘合剂体系及其在液体浸没目的中的应用
公开(公告)号：WO2005019365A2
公开(公告)日：2005-03-03
申请号：PCT/IB2004/051397
申请日：2004-08-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VERSTEGEN, Emile, J., K. , KLOOSTERBOER, Johan, G. , STAPERT, Hendrik, R. , NEIJZEN, Jacobus, H., M. , VAN SANTEN, Helmar
发明人： VERSTEGEN, Emile, J., K. , KLOOSTERBOER, Johan, G. , STAPERT, Hendrik, R. , NEIJZEN, Jacobus, H., M. , VAN SANTEN, Helmar
IPC分类号： C09J4/00
CPC分类号： C09J135/02
摘要： A non-leaching adhesive system and its use in a liquid immersion objective for immersion-writing of masters for optical discs are disclosed. The adhesive system comprises at least one monomer, selected from among the group of acrylate and methacrylate monomers, allylic monomers, norbornene monomers, hybrid monomers thereof, containing chemically different polymerizable groups, and multifunctional thiol monomers, provided that said thiol is used in combination with at least one of said non-thiol monomers; and a polymerization initiator. At least one of said monomers, not being a thiol, is provided with at least two functional polymerizable groups to obtain a crosslinked polymer network. The polymerization initiator is preferably an initiator that can be activated both thermally and with UV radiation. The adhesive system may further contain a reactive diluent. Further the use of the present adhesive system in mounting a liquid immersion objective is disclosed.
摘要翻译：公开了一种非浸出粘合剂体系及其在液浸物镜中的用途，用于浸入式书写光盘原版。所述粘合剂体系包含至少一种选自丙烯酸酯和甲基丙烯酸酯单体，烯丙基单体，降冰片烯单体，其含有化学上不同的可聚合基团的混合单体和多官能硫醇单体的单体，条件是所述巯基与至少一种所述非硫醇单体; 和聚合引发剂。至少一种所述单体不是巯基，具有至少两个官能可聚合基团以获得交联聚合物网络。聚合引发剂优选为可以在热和UV辐射下活化的引发剂。粘合剂体系可以进一步含有反应性稀释剂。此外公开了使用本粘合剂系统安装液浸物镜。

6. 发明申请

WO2005119661A1 RECORD CARRIER WITH IMPROVED MODULATION AND ASYMMETRY 审中-公开
标题翻译：具有改进的调制和不对称的记录载体
公开(公告)号：WO2005119661A1
公开(公告)日：2005-12-15
申请号：PCT/IB2005/051755
申请日：2005-05-30
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , MEINDERS, Erwin, R. , NEIJZEN, Jacobus, H., M.
发明人： MEINDERS, Erwin, R. , NEIJZEN, Jacobus, H., M.
IPC分类号： G11B7/0045
CPC分类号： G11B7/261 , G11B7/00456 , G11B7/24085
摘要： The invention relates to a record carrier comprising a train of marks and lands (14, 15, 23), which has a plurality of marks comprising shortest marks (1) and other marks (2) and a plurality of lands between said marks in a direction of said train of marks and lands comprising shortest lands (28) and other lands (27), said train of marks and lands (14, 15, 23) having information read by applying a light beam, and a land area not being part of said train of marks and lands. To provide a record carrier with an improved modulation of all marks without sacrificing tangential density and to further provide a record carrier with a reduced or substantially no asymmetry, it is proposed that said shortest marks (1) and leading and trailing edges (3) of said other marks (2) have a width larger than that of a central mark section (4) between said leading and trailing edges (3) of said other marks (2) and that said lands between said marks (19) in said direction of said train of marks and lands (15) have a reflectivity lower than that of said land area. The invention further relates to a method and a device for manufacturing such a record carrier.
摘要翻译：本发明涉及一种记录载体，其包括一列标记和焊盘（14,15,23），其具有包括最短标记（1）和其它标记（2）的多个标记以及在所述标记和所述焊盘之间的所述标记之间的多个焊盘所述包括最短地面（28）和其他陆地（27）的所述标记和土地列车的方向，所述具有通过施加光束读取信息的标记和地面列车（14,15,23）以及不是部分的陆地区域的所有标记和土地的火车。为了提供具有改进的所有标记的调制而不牺牲切向密度并且进一步提供具有减小的或基本上不对称的记录载体的记录载体，提出所述最短标记（1）和前沿和后沿（3）所述其他标记（2）的宽度大于所述另一标记（2）的所述前缘和后缘（3）之间的中心标记部分（4）的宽度，并且所述标记（19）所述标记和土地列车（15）的反射率低于所述土地面积。本发明还涉及用于制造这种记录载体的方法和装置。

7. 发明申请

WO2004057590A1 METHOD AND DEVICE FOR IRRADIATING SPOTS ON A LAYER 审中-公开
标题翻译：用于辐射层的方法和装置
公开(公告)号：WO2004057590A1
公开(公告)日：2004-07-08
申请号：PCT/IB2003/005708
申请日：2003-11-20
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VAN SANTEN, Helmar , NEIJZEN, Jacobus, H., M.
发明人： VAN SANTEN, Helmar , NEIJZEN, Jacobus, H., M.
IPC分类号： G11B7/135
CPC分类号： G03F7/70341 , G11B7/122 , G11B7/1374 , G11B7/261
摘要： For irradiating a layer a radiation beam is directed and focussed to a spot on the layer, relative movement of the layer relative to the optical element is caused so that, successively, different portions of the layer are irradiated and an interspace between a surface of the optical element nearest to the layer is maintained. Furthermore, at least a portion of the interspace through which the radiation irradiates the spot on the layer is maintained filled with a liquid, the liquid being supplied via a supply conduit and flowing out of an outflow opening through a total projected cross-sectional passage area in a plane parallel to the layer. The outflow opening or a plurality of the outflow openings are positioned such that, seen in a direction perpendicular to the layer, the total cross-sectional area has a centre in the portion of the interspace through which the radiation irradiates the spot.
摘要翻译：为了照射层，辐射束被引导并聚焦到层上的斑点，引起层相对于光学元件的相对运动，使得相继地照射该层的不同部分和在该层的表面之间的间隙保持最靠近层的光学元件。此外，辐射照射到层上的斑点的间隙的至少一部分保持充满液体，液体经由供应管道供给，并通过总投影横截面通过面积流出流出开口在与平面平行的平面上。流出开口或多个流出开口定位成使得从垂直于该层的方向看，总横截面积在该间隙的中心位置，辐射辐射穿过该区域。

8. 发明申请

WO2011027262A1 FLUID FILTERING DEVICE 审中-公开
标题翻译：流体过滤装置
公开(公告)号：WO2011027262A1
公开(公告)日：2011-03-10
申请号：PCT/IB2010/053811
申请日：2010-08-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , WIMBERGER-FRIEDL, Reinhold , NEIJZEN, Jacobus, H., M. , MAAS, Joost, H.
发明人： WIMBERGER-FRIEDL, Reinhold , NEIJZEN, Jacobus, H., M. , MAAS, Joost, H.
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/502753 , B01L2200/027 , B01L2300/0654 , B01L2300/0803 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/0406 , Y10T29/4998
摘要： The invention relates to a fluid filtering device comprising a filter (2) for filtering a fluid and a substrate (3) comprising a collecting structure (4) for collecting the filtered fluid from the filter (2). An adhesive (5) holds the filter (2) in place with respect to the collecting structure (4). The filter (2), the substrate (3) with the collecting structure (4) and the adhesive (5) are arranged such that the collecting structure (4) contacts the filter (2) and the filter (2) is attached to the substrate (3) by the adhesive (5). The collecting structure is very close to the filter and the adhesive ensures that the collecting structure remains very close to the filter. The filtered fluid can therefore be collected very efficiently and very fast. The fluid filtering device is preferentially used for filtering blood in a biosensing device.
摘要翻译：本发明涉及一种流体过滤装置，其包括用于过滤流体的过滤器（2）和包括用于从过滤器（2）收集过滤流体的收集结构（4）的基底（3）。粘合剂（5）将过滤器（2）相对于收集结构（4）保持在适当的位置。过滤器（2），具有收集结构（4）的基板（3）和粘合剂（5）被布置成使得收集结构（4）接触过滤器（2），并且过滤器（2）附接到基材（3）由粘合剂（5）。收集结构非常接近过滤器，粘合剂确保收集结构保持非常接近过滤器。因此，可以非常有效和非常快地收集过滤的流体。流体过滤装置优选用于过滤生物传感装置中的血液。

9. 发明申请

WO2006064415A3 OPTICAL STORAGE MEDIUM USING A SEPARATE REFERENCE BEAM LAYER 审中-公开
公开(公告)号：WO2006064415A3
公开(公告)日：2006-06-22
申请号：PCT/IB2005/054098
申请日：2005-12-07
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , NEIJZEN, Jacobus, H., M.
发明人： NEIJZEN, Jacobus, H., M.
IPC分类号： G11B7/013 , G11B7/24 , G11B7/258 , G11B7/14
摘要： The present invention relates to a data medium to be read out by a focused reading beam having a predetermined wavelength. The data medium implements a new concept of generating a reference beam, by comprising a reference beam interface, which, in the propagation direction of the impinging reading beam, is arranged either in front of a data layer with a pit-and-land structure, and is partially reflective while the pit and land interface sections are fully reflective for the reading beam. Or the reference layer is arranged behind the first and second reflective interface sections, and is fully reflective while the pit and land interlace sections are partially reflective for the reading beam. The data medium of the invention has a number of between 5 and 20 channel-bit cells contained in a reference area A-ef defined by the square of the ratio between the reading beam wavelength WL and the numerical aperture NA of an optical system focusing the reading beam. The ratio between the sum of the areas of all pit interface sections and the sum of the areas of all land interface sections of the pit-and-land structure is between 0.4 and 0.6.

10. 发明申请

WO2005119664A1 RECORD CARRIER COMPRISING A ROM MARK AND A PLAYBACK DEVICE FOR RETRIEVING THE ROM MARK 审中-公开
标题翻译：包含ROM标记的记录载体和用于检索ROM标记的回放设备
公开(公告)号：WO2005119664A1
公开(公告)日：2005-12-15
申请号：PCT/IB2005/051756
申请日：2005-05-30
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , MEINDERS, Erwin, R. , NEIJZEN, Jacobus, H., M.
发明人： MEINDERS, Erwin, R. , NEIJZEN, Jacobus, H., M.
IPC分类号： G11B7/007
CPC分类号： G11B7/00736 , G11B7/14 , G11B20/00086 , G11B20/00586
摘要： In order to distinguish a duplicated record carrier from an original record carrier a pattern is included in a ROM type record carrier that is oriented perpendicular to the reading direction. During illegal duplication the spatial relationship is disturb which can be easily detected. The patterns can be read out simultaneously by the same single read-out spot by including both patterns within the diameter of the optical spot thus guaranteeing that the read-out patterns are actually still spatially close together. Special patterns can be used that allow an easy detection of disturbances caused by the illegal duplication.
摘要翻译：为了将复制的记录载体与原始记录载体区分开，图案被包括在垂直于读取方向的ROM型记录载体中。在非法复制过程中，空间关系是可以轻易检测到的干扰。通过将两个图案包括在光点的直径内，可以通过将相同的单个读出光点同时读出图案，从而保证读出图案实际上仍然在空间上靠近在一起。可以使用特殊模式，可以方便地检测非法复制造成的干扰。

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