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1. 发明授权

US08497138B2 Method for cell selection 有权
标题翻译：细胞选择方法
公开(公告)号：US08497138B2
公开(公告)日：2013-07-30
申请号：US12895273
申请日：2010-09-30
申请人： Julian Burke , Alasdair Robertson , Xiao Zhang
发明人： Julian Burke , Alasdair Robertson , Xiao Zhang
IPC分类号： G01N33/53 , G01N33/00
CPC分类号： G01N33/5044
摘要： In one aspect the present invention provides a method for selecting a cell or cell colony which produces a polypeptide of interest, comprising a) providing a medium comprising cells and a detection agent, wherein the detection agent is associated with a detectable signal and the detection agent is capable of binding to the polypeptide of interest; b) providing a solid phase having a capture agent disposed thereon, wherein the capture agent is capable of binding to the polypeptide of interest; c) contacting the medium with the solid phase; d) detecting the signal associated with the detection agent; and e) selecting a cell or cell colony associated with the signal, wherein presence of the signal is indicative of a cell or cell colony which produces the polypeptide of interest.
摘要翻译：在一个方面，本发明提供了选择产生感兴趣多肽的细胞或细胞集落的方法，其包括a）提供包含细胞和检测剂的培养基，其中所述检测剂与可检测信号相关联，并且所述检测剂能够结合目的多肽; b）提供其上设置有捕获剂的固相，其中捕获剂能够结合感兴趣的多肽; c）使介质与固相接触; d）检测与检测剂相关的信号; 和e）选择与所述信号相关的细胞或细胞集落，其中所述信号的存在指示产生感兴趣多肽的细胞或细胞集落。

2. 发明授权

US08622719B2 Hydraulic pump structure for wind turbine generator or tidal current generator and method of mounting hydraulic pump 失效
标题翻译：用于风力发电机或潮汐发电机的液压泵结构和安装液压泵的方法
公开(公告)号：US08622719B2
公开(公告)日：2014-01-07
申请号：US12997671
申请日：2010-11-30
申请人： Kazuhisa Tsutsumi , Noguchi Toshihide , Yasuhiro Korematsu , Masayuki Shimizu , Alasdair Robertson , Uwe Stein , Hauke Karstens
发明人： Kazuhisa Tsutsumi , Noguchi Toshihide , Yasuhiro Korematsu , Masayuki Shimizu , Alasdair Robertson , Uwe Stein , Hauke Karstens
IPC分类号： F04B17/00 , F04B35/00 , F04B1/04 , F03D9/00 , H02P9/04
CPC分类号： F03D9/28 , F03B13/26 , F03D9/25 , F03D15/00 , F03D80/70 , F04B1/0538 , F05B2260/406 , Y02E10/28 , Y02E10/38 , Y02E10/721 , Y02E10/726 , Y02P80/158 , Y10T29/49236
摘要： A hydraulic pump unit includes a cylindrical member that is fit into an outer circumference of the main shaft and a hydraulic pump body arranged on an outer circumferential side of the cylindrical member. The hydraulic pump body includes a ring cam mounted on the outer circumference of the cylindrical member, a pump bearing, a pump housing, a plurality of pistons housed in the pump housing and actuated by the ring cam, and a plurality of cylinders which guide the plurality of pistons in a radial direction and are arranged in a circumferential direction. The hydraulic pump unit is configured such that the pump unit is insertably fixed to the main shaft by the cylindrical member.
摘要翻译：液压泵单元包括配合到主轴的外周的圆柱形构件和布置在圆筒构件的外周侧上的液压泵体。液压泵主体包括安装在圆柱形构件的外圆周上的环形凸轮，泵轴承，泵壳体，容纳在泵壳体中并由环形凸轮驱动的多个活塞，以及多个气缸，其引导多个活塞在径向上并且沿圆周方向布置。液压泵单元被构造成使得泵单元通过圆柱形构件可插入地固定到主轴。

3. 发明申请

US20130216403A1 METHOD OF MAINTAINING HYDRAULIC PUMP IN A RENEWABLE ENERGY TURBINE GENERATOR 审中-公开
标题翻译：在可再生能源涡轮发电机中维护液压泵的方法
公开(公告)号：US20130216403A1
公开(公告)日：2013-08-22
申请号：US13390872
申请日：2011-08-30
申请人： Stephen Salter , Uwe Stein , Henry Dodson , Robert Fox , Alasdair Robertson , Tom McGrath
发明人： Stephen Salter , Uwe Stein , Henry Dodson , Robert Fox , Alasdair Robertson , Tom McGrath
IPC分类号： F04B9/02
CPC分类号： F04B9/02 , F03D9/28 , F03D15/00 , F03D80/00 , F03D80/50 , F03D80/70 , F03D80/88 , F04B1/053 , Y02B10/30 , Y02E10/726 , Y02P70/523 , Y02P80/158 , Y10T29/49236
摘要： A hydraulic pump comprises (1) an outward ring (24), including demountable blocks (30) comprising piston cylinders (32), and an inward ring (21), comprising a ring cam (23), coupled through a drive shaft (8) to the blades of a turbine (4). To enable maintenance, the outward ring is decoupled from a torque limiting device (16, 17) and rotated relative to the inward ring. Demountable blocks are then removed from the outward ring using a crane (61) including a line (62) extending from above the centre of mass of the demountable block and including a resilient portion (66) so that although the crane supplies the majority of the force required to remove the demountable block, an operator provides some force, enabling the process to be controlled. The method is suitable for maintaining large hydraulic pumps in wind turbine nacelles (2).
摘要翻译：液压泵包括（1）向外的环（24），包括可拆卸的块（30），包括活塞缸（32）和向内的环（21），包括环形凸轮（23），其通过驱动轴（8 ）到涡轮（4）的叶片。为了进行维护，向外的环与扭矩限制装置（16,17）分离并相对于向内的环旋转。然后使用包括从可拆卸块的质心上方延伸的线（62）的起重机（61）将可拆卸块从所述向外环移除并且包括弹性部分（66），使得尽管起重机提供大部分拆卸可拆卸块所需的力，操作员提供一些力量，使过程得以控制。该方法适用于维护风力发动机舱（2）中的大型液压泵。

4. 发明申请

US20120063929A1 HYDRAULIC PUMP STRUCTURE FOR WIND TURBINE GENERATOR OR TIDAL CURRENT GENERATOR AND METHOD OF MOUNTING HYDRAULIC PUMP 失效
标题翻译：风力涡轮发电机或潮流发电机的液压泵结构及液压泵安装方法
公开(公告)号：US20120063929A1
公开(公告)日：2012-03-15
申请号：US12997671
申请日：2010-11-30
申请人： Kazuhisa Tsutsumi , Toshihide Noguchi , Yasuhiro Korematsu , Masayuki Shimizu , Alasdair Robertson , Uwe Stein , Hauke Karstens
发明人： Kazuhisa Tsutsumi , Toshihide Noguchi , Yasuhiro Korematsu , Masayuki Shimizu , Alasdair Robertson , Uwe Stein , Hauke Karstens
IPC分类号： F04B35/00 , B23P15/00
CPC分类号： F03D9/28 , F03B13/26 , F03D9/25 , F03D15/00 , F03D80/70 , F04B1/0538 , F05B2260/406 , Y02E10/28 , Y02E10/38 , Y02E10/721 , Y02E10/726 , Y02P80/158 , Y10T29/49236
摘要： An object of the present invention is to provide a hydraulic pump structure which improves the ease of mounting the hydraulic pump on the main shaft, and a method of mounting the hydraulic pump which can be performed in a simplified manner. A hydraulic pump unit 10 is formed by unitizing a cylindrical member 46 fit into an outer circumference of the main shaft 12 and a hydraulic pump body 76 arranged on an outer circumferential side of the cylindrical member 46. The hydraulic pump body 76 comprises a ring cam 52 mounted on the outer circumference of the cylindrical member 46, a pump bearing 54, a pump housing 34, a plurality of piston 58 housed in the pump housing 34 and actuated by the ring cam, and a plurality of cylinders 60 which guide the plurality of pistons in a radial direction and are arranged in a circumferential direction, and the hydraulic pump unit 10 is configured such that the pump unit 10 is insertably fixed to the main shaft 12 by the cylindrical member 46.
摘要翻译：本发明的目的是提供一种液压泵结构，其提高了将液压泵安装在主轴上的容易性，以及可以简化地执行液压泵的安装方法。液压泵单元10通过将配合到主轴12的外周的圆柱形构件46和布置在圆筒构件46的外周侧上的液压泵体76组合而形成。液压泵体76包括环形凸轮 52，安装在圆柱形构件46的外圆周上，泵轴承54，泵壳体34，容纳在泵壳体34中并由环形凸轮致动的多个活塞58以及多个引导多个的活塞沿圆周方向排列，液压泵单元10构成为使得泵单元10通过圆筒构件46可插入地固定在主轴12上。

5. 发明申请

US20130067900A1 POWER GENERATING APPARATUS OF RENEWABLE ENERGY TYPE 审中-公开
标题翻译：可再生能源发电设备
公开(公告)号：US20130067900A1
公开(公告)日：2013-03-21
申请号：US13390571
申请日：2011-05-30
申请人： Kazuhisa Tsutsumi , Masayuki Shimizu , Atsushi Maekawa , Toshihide Noguchi , Yasuhiro Korematsu , Niall Caldwell , Daniil Dumnov , Stephen Salter , Uwe Stein , William Rampen , Robert Fox , Alasdair Robertson , Stephen Laird , Hauke Karstens , Venkata Pappala
发明人： Kazuhisa Tsutsumi , Masayuki Shimizu , Atsushi Maekawa , Toshihide Noguchi , Yasuhiro Korematsu , Niall Caldwell , Daniil Dumnov , Stephen Salter , Uwe Stein , William Rampen , Robert Fox , Alasdair Robertson , Stephen Laird , Hauke Karstens , Venkata Pappala
IPC分类号： F04B49/22 , F04B23/00
CPC分类号： F04B49/22 , F03C1/0403 , F03D9/28 , F03D15/00 , F03D15/20 , F04B1/0404 , F04B17/02 , F04B23/00 , F05B2260/406 , F16H39/02 , F16H61/4035 , Y02E10/722 , Y02E10/725 , Y02E60/17 , Y02P80/158
摘要： A power generating apparatus includes a rotating shaft, a hydraulic pump driven by the rotating shaft, a hydraulic motor driven by pressurized oil supplied from the hydraulic pump, and a generator coupled to the hydraulic motor. Each of the hydraulic pump and motor includes working chambers each defined by a cylinder and a piston, a high pressure manifold and a low pressure manifold. Each of the high and low pressure manifolds includes branch channels connected to the working chambers and a merging channel connected to a high or low pressure oil line. The branch channels are equipped with high or low pressures valves, joined together and merged into the merging channel.
摘要翻译：发电装置包括旋转轴，由旋转轴驱动的液压泵，由从液压泵供给的加压油驱动的液压马达和联接到液压马达的发电机。液压泵和电动机中的每一个包括由气缸和活塞，高压歧管和低压歧管限定的工作室。高压歧管和低压歧管中的每一个包括连接到工作室的分支通道和连接到高压或低压油管线的合流通道。分支通道配有高压或低压阀，连接在一起并合并入合并通道。

6. 发明申请

US20130049371A1 OIL SUPPLY IN RENEWABLE ENERGY TURBINE GENERATOR 审中-公开
标题翻译：可再生能源涡轮发电机的供油
公开(公告)号：US20130049371A1
公开(公告)日：2013-02-28
申请号：US13390897
申请日：2011-08-30
申请人： Uwe Stein , Robert Fox , Alasdair Robertson , William Rampen
发明人： Uwe Stein , Robert Fox , Alasdair Robertson , William Rampen
IPC分类号： F03D11/02
CPC分类号： F03D9/28 , F03D9/25 , F03D15/20 , F03D80/60 , F03D80/70 , Y02E10/72 , Y02P80/158
摘要： A renewable energy turbine generator (1), such as a wind turbine generator, comprises a hydraulic pump (20), a hydraulic motor (24) and an oil circuit (26, 28) connecting the hydraulic pump and the hydraulic motor. Oil in the low pressure side (28) of the oil circuit is cooled and supplied to the working chambers (95) of the hydraulic pump. A reduced temperature oil feed provides additionally cooled oil to the bearings of the hydraulic pump and the hydraulic motor. Thus, cooler and more viscous oil is supplied to the bearings (84) of the hydraulic pump and/or hydraulic motor and warmer and less viscous oil is supplied to the working chambers, increasing the efficiency and lifetime of the bearings and of the working portions of the hydraulic pump and motor.
摘要翻译：诸如风力涡轮发电机的可再生能量涡轮发电机（1）包括连接液压泵和液压马达的液压泵（20），液压马达（24）和油路（26,28）。油路的低压侧（28）中的油被冷却并供给到液压泵的工作室（95）。降温油进料为液压泵和液压马达的轴承提供另外冷却的油。因此，冷却器和更粘稠的油被供应到液压泵和/或液压马达的轴承（84），并且较暖和较低粘度的油被供应到工作室，从而提高轴承和工作部分的效率和使用寿命的液压泵和电机。

7. 发明申请

US20130047594A1 COVER FOR HYDRAULIC PUMP IN RENEWABLE ENERGY TURBINE GENERATOR 审中-公开
标题翻译：可再生能源涡轮发电机液压泵盖
公开(公告)号：US20130047594A1
公开(公告)日：2013-02-28
申请号：US13390364
申请日：2011-08-30
申请人： Uwe Stein , Henry Dodson , Alasdair Robertson
发明人： Uwe Stein , Henry Dodson , Alasdair Robertson
IPC分类号： F15B13/00
CPC分类号： F04B1/0538 , F03D9/25 , F03D9/28 , F03D15/00 , F03D15/20 , F03D80/50 , F04B1/0404 , F04B53/16 , Y02E10/72 , Y02P80/158
摘要： A large hydraulic radial piston pump suitable to be driven by the turbine of a wind turbine generator has a circular cover formed from at least three cover segments. Underneath the cover segments a seal in the form of a vulcanised rubber band extends around the entire periphery of the pump. Thus, the cover can be readily removed within the difficult to access location of a wind turbine nacelle, but a reliable seal can still be formed. An air pocket outside the seal, or within the seal, facilitates pulsatile flow into the cylinders of the pump during operation.
摘要翻译：适合于由风力涡轮发电机的涡轮驱动的大型液压径向柱塞泵具有由至少三个盖段形成的圆形盖。在盖部分下方，硫化橡胶带形式的密封围绕泵的整个周边延伸。因此，可以在风力涡轮机舱的难以进入的位置容易地移除盖，但是仍然可以形成可靠的密封。在密封件外部或密封件内的空气袋在操作期间促进脉动流入泵的气缸。

8. 发明申请

US20120285150A1 POWER GENERATING APPARATUS OF RENEWABLE ENERGY TYPE 审中-公开
标题翻译：可再生能源发电设备
公开(公告)号：US20120285150A1
公开(公告)日：2012-11-15
申请号：US13390362
申请日：2011-11-30
申请人： Takuro Kameda , Alasdair Robertson , Henry Dodson , Stein Uwe
发明人： Takuro Kameda , Alasdair Robertson , Henry Dodson , Stein Uwe
IPC分类号： F15B13/00
CPC分类号： F03D9/28 , F03D9/25 , F03D15/00 , F03D15/20 , F03D80/70 , F05B2260/406 , F05B2260/96 , Y02E10/726 , Y02P80/158
摘要： A power generating apparatus is provided with a hub rotated by the renewable energy received via a blade, a rotating shaft connected to the hub, a hydraulic pump mounted on the rotating shaft and driven by rotation of the rotating shaft, a hydraulic motor driven by pressurized oil from the hydraulic pump, a generator coupled to the hydraulic motor, a support providing reaction torque on the hydraulic pump from the rotating shaft while allowing a displacement of the hydraulic pump in a direction perpendicular to an axis of the rotating shaft, the hydraulic pump being supported by a nacelle through the support, and a pressurized-oil piping which is at least partially constituted of a flexible tube and which connects an outlet port of the hydraulic pump to an inlet port of the hydraulic motor to supply the pressurized oil from the hydraulic pump to the hydraulic motor.
摘要翻译：发电装置设置有通过叶片接收的可再生能量旋转的轮毂，连接到轮毂的旋转轴，安装在旋转轴上并由旋转轴旋转驱动的液压泵，通过加压驱动的液压马达来自液压泵的油，耦合到液压马达的发电机，支撑件，其从旋转轴在液压泵上提供反作用扭矩，同时允许液压泵在垂直于旋转轴的轴线的方向上移位，液压泵由机舱通过支撑件支撑，以及加压油管道，其至少部分地由柔性管构成，并且将液压泵的出口连接到液压马达的入口端口，以将压力油从液压泵到液压马达。

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