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1. 发明授权

US07552853B2 Low-profile vascular closure systems and methods of using same 失效
标题翻译：低调血管闭合系统及其使用方法
公开(公告)号：US07552853B2
公开(公告)日：2009-06-30
申请号：US11626633
申请日：2007-01-24
申请人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Scott J. Epperly , Kenneth A. Eliasen
发明人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Scott J. Epperly , Kenneth A. Eliasen
IPC分类号： A61B17/068
CPC分类号： A61B17/0057 , A61B17/0218 , A61B17/0644 , A61B17/0684 , A61B17/0686 , A61B17/07292 , A61B17/083 , A61B17/10 , A61B2017/00637 , A61B2017/00668 , A61B2017/22038 , A61B2090/037 , A61B2090/0801 , A61B2090/08021
摘要： A closure device for an arteriotomy includes an elongate tube having a distal opening. The elongate tube has least two opposing longitudinal slots and a pair of opposing corners defined where each slot meets the distal opening. A staple is disposed within the tube, the staple having at least two opposing legs aligned with the at least two slots. Each slot is pinched together adjacent the distal opening such that the opposing corners of each slot converge to cover the tip of the respective staple leg to guard the staple tips against contact with the tissue track. The corners of each slot are separable to permit the respective staple leg to pass there between.
摘要翻译：用于动脉切开术的闭合装置包括具有远端开口的细长管。细长管具有至少两个相对的纵向狭槽和一对相对的拐角，其中每个狭槽都与远端开口相接合。订书针设置在管内，订书针具有与至少两个狭槽对准的至少两个相对的支脚。每个狭槽被夹在邻近远端开口处，使得每个狭槽的相对的角部会聚以覆盖相应的钉腿的尖端，以保护钉末端免受与组织轨迹的接触。每个槽的角部是可分离的，以允许相应的短纤维腿在其间通过。

2. 发明申请

US20080177300A1 Low-Profile Vasculare Closure Systems and Methods of Using Same 失效
标题翻译：薄型Vasculare闭合系统及其使用方法
公开(公告)号：US20080177300A1
公开(公告)日：2008-07-24
申请号：US11626595
申请日：2007-01-24
申请人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Kenneth A. Eliasen , Scott J. Epperly
发明人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Kenneth A. Eliasen , Scott J. Epperly
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/0218 , A61B17/0644 , A61B17/0684 , A61B17/0686 , A61B17/07292 , A61B17/083 , A61B17/10 , A61B2017/00637 , A61B2017/00668 , A61B2017/22038 , A61B2090/037 , A61B2090/0801 , A61B2090/08021
摘要： A closure device for an arteriotomy includes an elongate hollow shaft and an elongate driver slidably disposed therein. The elongate hollow shaft includes a pair of a pair of opposing actuation tips disposed at a distal end thereof defining a staple chamber there between. An anvil extends into the staple chamber from one of the actuation tips. The closure device includes a release mechanism for spreading apart the pair of opposing actuation tips to provide a gap associated with the anvil, the gap dimensioned such that the staple may pass there through. A method of using the closure device is also disclosed.
摘要翻译：用于动脉切开术的闭合装置包括细长空心轴和可滑动地设置在其中的细长驱动器。细长空心轴包括一对相对的致动尖端，其设置在其远端处，在其之间限定缝合室。一个砧座从一个致动尖端延伸到钉仓中。闭合装置包括释放机构，用于展开该对相对的致动尖端以提供与砧座相关联的间隙，所述间隙的尺寸使得订书钉可能通过其中。还公开了使用封闭装置的方法。

3. 发明申请

US20080173691A1 Low-Profile Vascular Closure Systems and Methods of Using Same 审中-公开
标题翻译：薄型血管闭合系统及其使用方法
公开(公告)号：US20080173691A1
公开(公告)日：2008-07-24
申请号：US11626567
申请日：2007-01-24
申请人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Kenneth A. Eliasen , Scott J. Epperly
发明人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Kenneth A. Eliasen , Scott J. Epperly
IPC分类号： A61B17/068
CPC分类号： A61B17/0057 , A61B17/0218 , A61B17/0644 , A61B17/0684 , A61B17/0686 , A61B17/07292 , A61B17/083 , A61B17/10 , A61B2017/00637 , A61B2017/00668 , A61B2017/22038 , A61B2090/037 , A61B2090/0801 , A61B2090/08021
摘要： A method for closing an arteriotomy includes providing a guiding system and a closure system. The guiding system is mounted over a dilator, and advanced along a guidewire through the arteriotomy and into the blood vessel lumen. The guiding system includes two stabilization wire guides. A retention foot is disposed at a distal portion of each stabilization wire guide, the foot being deployable into contact against an inner surface of the vessel wall. The guidewire and dilator are withdrawn from the patient, leaving the stabilization wire guides in place. The closure system carries a stapler and is advanced along the stabilization wire guides to an extraluminal position. The stapler is then activated to close the arteriotomy. The retention feet are undeployed and the guiding and closure systems are withdrawn from the body, leaving a staple to hold the arteriotomy closed.
摘要翻译：用于闭合动脉切开术的方法包括提供引导系统和闭合系统。引导系统安装在扩张器上，并沿着导丝通过动脉切开术进入血管腔。引导系统包括两个稳定导线导轨。保持脚设置在每个稳定导线器的远端部分处，所述脚部可展开成与血管壁的内表面接触。引导线和扩张器从患者身体中取出，使稳定导线导向器就位。封闭系统承载订书机，并且沿着稳定导丝器前进到外部位置。然后激活订书机以关闭动脉切开术。保持脚未被部署，并且引导和闭合系统从身体排出，留下钉以将动脉切开术闭合。

4. 发明授权

US07628306B2 Low-profile vascular closure systems and methods of using same 失效
标题翻译：低调血管闭合系统及其使用方法
公开(公告)号：US07628306B2
公开(公告)日：2009-12-08
申请号：US11626616
申请日：2007-01-24
申请人： Matthew F. Spurchise , Richard D. Lobello , Juan-Pablo Mas , Kenneth A. Eliasen , Scott J. Epperly
发明人： Matthew F. Spurchise , Richard D. Lobello , Juan-Pablo Mas , Kenneth A. Eliasen , Scott J. Epperly
IPC分类号： A61B17/068
CPC分类号： A61B17/0057 , A61B17/0218 , A61B17/0644 , A61B17/0684 , A61B17/0686 , A61B17/07292 , A61B17/083 , A61B17/10 , A61B2017/00637 , A61B2017/00668 , A61B2017/22038 , A61B2090/037 , A61B2090/0801 , A61B2090/08021
摘要： A closure device for an arteriotomy includes an elongate tube having a distal opening, a staple disposed within the tube, and a frangible cap mounted across the distal opening to guard the staple tips against contact with the tissue track. The frangible cap is pierced, fractured or torn when the staple is advanced through the distal opening. A portion of the torn frangible cap may be implanted with the staple as a pledget. The staple may be carried within the elongate tube by a stapler comprising an elongate hollow shaft and an elongate driver slidably disposed therein. A pair of opposing actuation tips is disposed at a distal end of the hollow shaft to define an open-sided staple chamber there between. An anvil is fixedly disposed within the staple chamber, which holds at least a proximal portion of the staple.
摘要翻译：用于动脉切开术的闭合装置包括具有远侧开口的细长管，设置在管内的钉，以及横跨远侧开口安装的易碎帽，以防止钉头与组织轨迹接触。当钉子穿过远端开口时，易碎的帽子被刺穿，断裂或撕裂。破裂的易碎帽的一部分可以用钉子植入。订书钉可以通过包括细长中空轴和可滑动地设置在其中的细长驱动器的订书机在细长管内承载。一对相对的致动尖端设置在空心轴的远端处，以在其间限定开放侧缝合室。砧座固定地设置在钉仓内，其至少保持钉的近端部分。

5. 发明申请

US20080173693A1 Low-Profile Vascular Closure Systems and Methods of Using Same 失效
标题翻译：薄型血管闭合系统及其使用方法
公开(公告)号：US20080173693A1
公开(公告)日：2008-07-24
申请号：US11626633
申请日：2007-01-24
申请人： Juan Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Scott J. Epperly , Kenneth A. Eliasen
发明人： Juan Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Scott J. Epperly , Kenneth A. Eliasen
IPC分类号： A61B17/068
CPC分类号： A61B17/0057 , A61B17/0218 , A61B17/0644 , A61B17/0684 , A61B17/0686 , A61B17/07292 , A61B17/083 , A61B17/10 , A61B2017/00637 , A61B2017/00668 , A61B2017/22038 , A61B2090/037 , A61B2090/0801 , A61B2090/08021
摘要： A closure device for an arteriotomy includes an elongate tube having a distal opening. The elongate tube has least two opposing longitudinal slots and a pair of opposing corners defined where each slot meets the distal opening. A staple is disposed within the tube, the staple having at least two opposing legs aligned with the at least two slots. Each slot is pinched together adjacent the distal opening such that the opposing corners of each slot converge to cover the tip of the respective staple leg to guard the staple tips against contact with the tissue track. The corners of each slot are separable to permit the respective staple leg to pass there between.
摘要翻译：用于动脉切开术的闭合装置包括具有远端开口的细长管。细长管具有至少两个相对的纵向狭槽和一对相对的拐角，其中每个狭槽都与远端开口相接合。订书针设置在管内，订书针具有与至少两个狭槽对准的至少两个相对的支脚。每个狭槽被夹在邻近远端开口处，使得每个狭槽的相对的角部会聚以覆盖相应的钉腿的尖端，以保护钉末端免受与组织轨迹的接触。每个槽的角部是可分离的，以允许相应的短纤维腿在其间通过。

6. 发明授权

US07766208B2 Low-profile vascular closure systems and methods of using same 失效
标题翻译：低调血管闭合系统及其使用方法
公开(公告)号：US07766208B2
公开(公告)日：2010-08-03
申请号：US11626595
申请日：2007-01-24
申请人： Scott J. Epperly , Richard D. Lobello , Juan-Pablo Mas , Matthew F. Spurchise , Katherine G. Coughlin , Kenneth A. Eliasen
发明人： Scott J. Epperly , Richard D. Lobello , Juan-Pablo Mas , Matthew F. Spurchise , Katherine G. Coughlin , Kenneth A. Eliasen
IPC分类号： A61B17/068
CPC分类号： A61B17/0057 , A61B17/0218 , A61B17/0644 , A61B17/0684 , A61B17/0686 , A61B17/07292 , A61B17/083 , A61B17/10 , A61B2017/00637 , A61B2017/00668 , A61B2017/22038 , A61B2090/037 , A61B2090/0801 , A61B2090/08021
摘要： A closure device for an arteriotomy includes an elongate hollow shaft and an elongate driver slidably disposed therein. The elongate hollow shaft includes a pair of a pair of opposing actuation tips disposed at a distal end thereof defining a staple chamber there between. An anvil extends into the staple chamber from one of the actuation tips. The closure device includes a release mechanism for spreading apart the pair of opposing actuation tips to provide a gap associated with the anvil, the gap dimensioned such that the staple may pass there through. A method of using the closure device is also disclosed.
摘要翻译：用于动脉切开术的闭合装置包括细长空心轴和可滑动地设置在其中的细长驱动器。细长空心轴包括一对相对的致动尖端，其设置在其远端处，在其之间限定缝合室。一个砧座从一个致动尖端延伸到钉仓中。闭合装置包括释放机构，用于展开该对相对的致动尖端以提供与砧座相关联的间隙，所述间隙的尺寸使得订书钉可能通过其中。还公开了使用封闭装置的方法。

7. 发明申请

US20080173692A1 Low-Profile Vascular Closure Systems and Methods of Using Same 失效
标题翻译：薄型血管闭合系统及其使用方法
公开(公告)号：US20080173692A1
公开(公告)日：2008-07-24
申请号：US11626616
申请日：2007-01-24
申请人： Matthew F. Spurchise , Richard D. Lobello , Juan-Pablo Mas , Kenneth A. Eliasen , Scott J. Epperly
发明人： Matthew F. Spurchise , Richard D. Lobello , Juan-Pablo Mas , Kenneth A. Eliasen , Scott J. Epperly
IPC分类号： A61B17/068
CPC分类号： A61B17/0057 , A61B17/0218 , A61B17/0644 , A61B17/0684 , A61B17/0686 , A61B17/07292 , A61B17/083 , A61B17/10 , A61B2017/00637 , A61B2017/00668 , A61B2017/22038 , A61B2090/037 , A61B2090/0801 , A61B2090/08021
摘要： A closure device for an arteriotomy includes an elongate tube having a distal opening, a staple disposed within the tube, and a frangible cap mounted across the distal opening to guard the staple tips against contact with the tissue track. The frangible cap is pierced, fractured or torn when the staple is advanced through the distal opening. A portion of the torn frangible cap may be implanted with the staple as a pledget. The staple may be carried within the elongate tube by a stapler comprising an elongate hollow shaft and an elongate driver slidably disposed therein. A pair of opposing actuation tips is disposed at a distal end of the hollow shaft to define an open-sided staple chamber there between. An anvil is fixedly disposed within the staple chamber, which holds at least a proximal portion of the staple.
摘要翻译：用于动脉切开术的闭合装置包括具有远侧开口的细长管，设置在管内的钉，以及横跨该远侧开口安装的易碎帽，以防止钉头与组织轨迹接触。当钉子穿过远端开口时，易碎的帽子被刺穿，断裂或撕裂。破裂的易碎帽的一部分可以用钉子植入。订书钉可以通过包括细长中空轴和可滑动地设置在其中的细长驱动器的订书机在细长管内承载。一对相对的致动尖端设置在空心轴的远端处，以在其间限定开放侧缝合室。砧座固定地设置在钉仓内，其至少保持钉的近端部分。

8. 发明申请

US20090259249A1 ARTERIOTOMY STAPLING SYSTEM FOR NON-ORTHOGONAL TISSUE TRACKS AND METHODS OF USE THEREIN 审中-公开
标题翻译：用于非正畸组织轨迹的非对称分层系统及其使用方法
公开(公告)号：US20090259249A1
公开(公告)日：2009-10-15
申请号：US12100532
申请日：2008-04-10
申请人： Richard D. Lobello
发明人： Richard D. Lobello
IPC分类号： A61B17/064 , A61B17/068
CPC分类号： A61B17/0057 , A61B17/1227 , A61B2017/00668 , A61B2017/0645
摘要： A stapling system for closing an arteriotomy includes a staple having four legs and a stapler that accommodates a non-orthogonal angle formed between a percutaneous tissue track and an arteriotomy. The staple is formed from a resilient material and is biased towards a static configuration in which a proximal portion of the staple is generally orthogonal to an imaginary axis of the stapling system. The stapler deforms the staple into a delivery configuration in which the pointed tips of the staple are staggered with respect to the axis of the stapling system. Once the staple is engaged in vessel tissue as desired about the arteriotomy, the staple is released from the stapler and tends to revert back to the static configuration in order to hold the arteriotomy closed. Methods of using the stapling system are also disclosed.
摘要翻译：用于闭合动脉切开术的缝合系统包括具有四个腿的缝合钉和一个适配在经皮组织轨道和动脉切开术之间形成的非正交角度的吻合器。订书钉由弹性材料形成，并被朝向静态构型偏置，其中订书钉的近端部分大致垂直于装订系统的假想轴线。订书机将订书钉变形成输送构型，其中订书钉的尖端相对于装订系统的轴线交错布置。一旦订书钉按照关于动脉切开术的需要接合在血管组织中，则订书钉从缝合器释放并趋于回复到静态构型以便将动脉切开术闭合。还公开了使用缝合系统的方法。

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