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1. 发明授权

US07815673B2 Double-walled stent system 有权
标题翻译：双壁支架系统
公开(公告)号：US07815673B2
公开(公告)日：2010-10-19
申请号：US12060332
申请日：2008-04-01
申请人： Eliot Bloom , Gian Pellegrini , Juan-Pablo Mas , Nasser Rafiee , Morgan House
发明人： Eliot Bloom , Gian Pellegrini , Juan-Pablo Mas , Nasser Rafiee , Morgan House
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/852 , A61F2/91 , A61F2/915 , A61F2002/823 , A61F2002/825 , A61F2002/828 , A61F2002/91558 , A61F2002/91591 , A61F2220/0058 , A61F2230/0013 , A61F2230/0054 , A61F2230/0071 , A61F2230/0076 , A61F2250/0037 , A61F2250/0063 , A61F2250/0082
摘要： A double walled stent system particularly suited for treating abnormalities of the right ventricular outflow tract is disclosed having an exterior stent component and an interior stent component. The exterior stent component includes a plurality of longitudinally-extending connectors such as straight or sinusoidal bands. The interior stent component has a generally tubular cylindrical body and is centered within the exterior stent component. The stent system has a contracted delivery configuration and a radially expanded configuration for contacting the vessel wall. When deployed, the longitudinally-extending connectors of the exterior stent component come in contact with the vessel wall and fix the stent system to the treatment site. The interior stent component also radially expands but remains centered inside the exterior component and makes little to no contact with the vessel wall.
摘要翻译：公开了一种特别适用于治疗右心室流出道异常的双壁支架系统，其具有外部支架部件和内部支架部件。外部支架部件包括多个纵向延伸的连接器，例如直线或正弦带。内部支架部件具有大致管状的圆柱形主体并且在外部支架部件内居中。支架系统具有收缩输送构型和用于接触血管壁的径向扩张构型。当部署时，外部支架部件的纵向延伸的连接器与血管壁接触并将支架系统固定到治疗部位。内部支架部件也径向扩张，但保持在外部部件的中心，并且几乎不与血管壁接触。

2. 发明申请

US20100204770A1 Stent Delivery System Permitting in Vivo Stent Repositioning 审中-公开
标题翻译：支架递送系统允许体内支架重新定位
公开(公告)号：US20100204770A1
公开(公告)日：2010-08-12
申请号：US12368419
申请日：2009-02-10
申请人： Juan-Pablo Mas , Nareak Douk
发明人： Juan-Pablo Mas , Nareak Douk
IPC分类号： A61F2/06 , A61M25/00
CPC分类号： A61F2/958 , A61F2002/9528 , A61F2002/9534 , A61F2002/9583 , A61F2250/0039
摘要： A stent delivery system is disclosed that includes a recapture component for at least partially collapsing an improperly deployed stent in situ to permit repositioning and re-deployment of the stent. The recapture component and the stent may be disconnected in situ to allow for removal of the stent delivery system. In one embodiment, the recapture component is a balloon having loops or hooks around a periphery thereof for receiving at least one removable tether that couples the balloon and stent together. In another embodiment, the recapture component is an expandable tubular component connected to the stent via the removable tether.
摘要翻译：公开了一种支架输送系统，其包括用于至少部分地将不适当部署的支架原位塌缩以允许支架的重新定位和重新部署的再捕获部件。重新捕获组件和支架可以在现场断开以允许移除支架输送系统。在一个实施例中，重新捕获部件是具有围绕其周边的环或钩的气囊，用于接收将球囊和支架联接在一起的至少一个可移除的系绳。在另一个实施例中，再捕获部件是经由可移除系绳连接到支架的可扩张管状部件。

3. 发明授权

US07727251B2 Low profile dilator for arteriotomy closure system 失效
标题翻译：用于动脉切开闭合系统的低调扩张器
公开(公告)号：US07727251B2
公开(公告)日：2010-06-01
申请号：US11739980
申请日：2007-04-25
申请人： Matthew Spurchise , Juan-Pablo Mas , Jeffrey J. Witts
发明人： Matthew Spurchise , Juan-Pablo Mas , Jeffrey J. Witts
IPC分类号： A61M29/00
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2090/062
摘要： A low profile, two lumen dilator is provided for an arteriotomy closure system. The dilator includes a first lumen adapted to receive a guidewire and a second lumen having a proximal segment that defines a blood marking lumen and a distal segment that receives the distal ends of stabilizers in a common pocket. The blood marking lumen and pocket are arranged in tandem. The guidewire lumen may extend the full length of the dilator or may be shortened to provide rapid exchange capability.
摘要翻译：为动脉切开术闭合系统提供了一种低调的两腔扩张器。扩张器包括适于接收导丝的第一腔和具有限定血液标记腔的近侧段的第二腔和在普通口袋中容纳稳定器的远端的远端段。血液标记腔和口袋串联排列。导丝管腔可以延伸扩张器的全长，或者可以缩短以提供快速的交换能力。

4. 发明申请

US20090264859A1 Catheter Having a Selectively Expandable Distal Tip 审中-公开
标题翻译：导管选择性扩展远端
公开(公告)号：US20090264859A1
公开(公告)日：2009-10-22
申请号：US12326591
申请日：2008-12-02
申请人： Juan-Pablo Mas
发明人： Juan-Pablo Mas
IPC分类号： A61M25/10 , A61F2/84
CPC分类号： A61M25/0074 , A61F2/95 , A61M25/005 , A61M25/1002 , A61M25/1006 , A61M2025/0024 , A61M2025/1015
摘要： A catheter for use in a medical procedure includes an elongate outer member, an elongate inner member and an expandable distal tip attached to a distal most end of at least one of the outer member or inner member, wherein the distal tip has a first shape and a second shape and the tip can be easily transformed between the first and second shapes to aid in navigation through a patient's vascular system. A method of using the catheter includes inserting the catheter into the vascular system, navigating the distal end of the catheter through the vascular system, determining an obstruction within the vascular system, modifying the expandable tip from the first shape to the second shape in response to the determination of the obstruction, advancing the modified expandable tip passed the determined obstruction and returning the modified expandable tip to the first shape upon passing the determined obstruction.
摘要翻译：用于医疗过程的导管包括细长外部构件，细长内部构件和连接到外部构件或内部构件中的至少一个的最远端的可扩展远侧末端，其中远侧末端具有第一形状和第二形状并且尖端可以容易地在第一形状和第二形状之间转换以帮助通过患者的血管系统导航。使用导管的方法包括将导管插入血管系统中，导管导管的远端穿过血管系统，确定血管系统内的梗阻，响应于第一形状将可扩张尖端修改为第二形状障碍物的确定，使修改的可扩张尖端前进通过确定的阻塞，并且在通过确定的阻塞物时将修改的可扩张尖端返回到第一形状。

5. 发明申请

US20080177300A1 Low-Profile Vasculare Closure Systems and Methods of Using Same 失效
标题翻译：薄型Vasculare闭合系统及其使用方法
公开(公告)号：US20080177300A1
公开(公告)日：2008-07-24
申请号：US11626595
申请日：2007-01-24
申请人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Kenneth A. Eliasen , Scott J. Epperly
发明人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Kenneth A. Eliasen , Scott J. Epperly
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/0218 , A61B17/0644 , A61B17/0684 , A61B17/0686 , A61B17/07292 , A61B17/083 , A61B17/10 , A61B2017/00637 , A61B2017/00668 , A61B2017/22038 , A61B2090/037 , A61B2090/0801 , A61B2090/08021
摘要： A closure device for an arteriotomy includes an elongate hollow shaft and an elongate driver slidably disposed therein. The elongate hollow shaft includes a pair of a pair of opposing actuation tips disposed at a distal end thereof defining a staple chamber there between. An anvil extends into the staple chamber from one of the actuation tips. The closure device includes a release mechanism for spreading apart the pair of opposing actuation tips to provide a gap associated with the anvil, the gap dimensioned such that the staple may pass there through. A method of using the closure device is also disclosed.
摘要翻译：用于动脉切开术的闭合装置包括细长空心轴和可滑动地设置在其中的细长驱动器。细长空心轴包括一对相对的致动尖端，其设置在其远端处，在其之间限定缝合室。一个砧座从一个致动尖端延伸到钉仓中。闭合装置包括释放机构，用于展开该对相对的致动尖端以提供与砧座相关联的间隙，所述间隙的尺寸使得订书钉可能通过其中。还公开了使用封闭装置的方法。

6. 发明申请

US20080173691A1 Low-Profile Vascular Closure Systems and Methods of Using Same 审中-公开
标题翻译：薄型血管闭合系统及其使用方法
公开(公告)号：US20080173691A1
公开(公告)日：2008-07-24
申请号：US11626567
申请日：2007-01-24
申请人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Kenneth A. Eliasen , Scott J. Epperly
发明人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Kenneth A. Eliasen , Scott J. Epperly
IPC分类号： A61B17/068
CPC分类号： A61B17/0057 , A61B17/0218 , A61B17/0644 , A61B17/0684 , A61B17/0686 , A61B17/07292 , A61B17/083 , A61B17/10 , A61B2017/00637 , A61B2017/00668 , A61B2017/22038 , A61B2090/037 , A61B2090/0801 , A61B2090/08021
摘要： A method for closing an arteriotomy includes providing a guiding system and a closure system. The guiding system is mounted over a dilator, and advanced along a guidewire through the arteriotomy and into the blood vessel lumen. The guiding system includes two stabilization wire guides. A retention foot is disposed at a distal portion of each stabilization wire guide, the foot being deployable into contact against an inner surface of the vessel wall. The guidewire and dilator are withdrawn from the patient, leaving the stabilization wire guides in place. The closure system carries a stapler and is advanced along the stabilization wire guides to an extraluminal position. The stapler is then activated to close the arteriotomy. The retention feet are undeployed and the guiding and closure systems are withdrawn from the body, leaving a staple to hold the arteriotomy closed.
摘要翻译：用于闭合动脉切开术的方法包括提供引导系统和闭合系统。引导系统安装在扩张器上，并沿着导丝通过动脉切开术进入血管腔。引导系统包括两个稳定导线导轨。保持脚设置在每个稳定导线器的远端部分处，所述脚部可展开成与血管壁的内表面接触。引导线和扩张器从患者身体中取出，使稳定导线导向器就位。封闭系统承载订书机，并且沿着稳定导丝器前进到外部位置。然后激活订书机以关闭动脉切开术。保持脚未被部署，并且引导和闭合系统从身体排出，留下钉以将动脉切开术闭合。

7. 发明授权

US08162975B2 Systems and methods for closing a percutaneous vascular puncture 失效
标题翻译：关闭经皮血管穿刺的系统和方法
公开(公告)号：US08162975B2
公开(公告)日：2012-04-24
申请号：US12437652
申请日：2009-05-08
申请人： Thierry Benjamin , Matthew Spurchise , Juan-Pablo Mas
发明人： Thierry Benjamin , Matthew Spurchise , Juan-Pablo Mas
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00557 , A61B2017/00597 , A61B2017/00623 , A61B2017/00659 , A61B2017/00672
摘要： A system and method for closing a percutaneous vessel puncture at the conclusion of a vascular catheterization procedure includes placement of an intravascular closure device having a radially and axially expandable tubular membrane and a radially expandable anchor at the distal end of the membrane. The closure device is placed, by a delivery catheter extending through the puncture site, with its anchor radially expanded in a location upstream of the puncture site to enable the force of a patient's blood flow to deploy the tubular membrane to a proximally extended configuration closing the puncture from within the vessel.
摘要翻译：在血管导管术过程结束时关闭经皮血管穿刺的系统和方法包括在膜的远端放置具有径向和轴向可扩张的管状膜和可径向扩张的锚固体的血管内闭合装置。闭合装置通过延伸穿过穿刺部位的输送导管放置，其锚固件在穿刺部位的上游位置径向扩张，以使得患者的血液流动的力能够将管状膜展开至近端延伸的构型，从船内穿刺。

8. 发明申请

US20100286725A1 Systems and Methods for Closing a Percutaneous Vascular Puncture 失效
标题翻译：闭合经皮血管穿刺的系统和方法
公开(公告)号：US20100286725A1
公开(公告)日：2010-11-11
申请号：US12437652
申请日：2009-05-08
申请人： Thierry Benjamin , Mathew Spurchise , Juan-Pablo Mas
发明人： Thierry Benjamin , Mathew Spurchise , Juan-Pablo Mas
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00557 , A61B2017/00597 , A61B2017/00623 , A61B2017/00659 , A61B2017/00672
摘要： A system and method for closing a percutaneous vessel puncture at the conclusion of a vascular catheterization procedure includes placement of an intravascular closure device having a radially and axially expandable tubular membrane and a radially expandable anchor at the distal sad of the membrane. The closure device is placed, by a delivery catheter extending through the puncture site, with its anchor radially expanded in a location upstream of the puncture site to enable the force of a patient's blood flow to deploy the tubular membrane to a proximally extended configuration closing the puncture from within the vessel.
摘要翻译：在血管导管插入术结束时闭合经皮血管穿刺的系统和方法包括在膜的远端伤口处放置具有径向和轴向可扩张的管状膜和径向可扩张的锚固体的血管内闭合装置。闭合装置通过延伸穿过穿刺部位的输送导管放置，其锚固件在穿刺部位的上游位置径向扩张，以使得患者的血液流动的力能够将管状膜展开至近端延伸的构型，从船内穿刺。

9. 发明申请

US20090270807A1 Aspiration Catheter Having An Internal Vacuum Accumulator 有权
标题翻译：吸入导管内置真空蓄能器
公开(公告)号：US20090270807A1
公开(公告)日：2009-10-29
申请号：US12108082
申请日：2008-04-23
申请人： Juan-Pablo Mas , Vincent J. Cangialosi
发明人： Juan-Pablo Mas , Vincent J. Cangialosi
IPC分类号： A61M1/00
CPC分类号： A61B17/22 , A61B2017/22039 , A61B2017/22079 , A61B2217/005 , A61M1/0031
摘要： An aspiration catheter is provided in which vacuum may be accumulated within the catheter and released suddenly within a distal region of the catheter to induce ingestion of intravascular matter into the catheter through an open distal port while avoiding large losses of suction common with catheters having long aspiration lumens. Conventional aspiration using the same catheter can subsequently complement the procedure by fully removing the ingested matter from the catheter.
摘要翻译：提供了一种抽吸导管，其中真空可以积聚在导管内并突然在导管的远端区域内释放，以通过开放的远端端口诱导将血管内物质摄取入导管，同时避免与具有长抽吸的导管相同的大量吸入损失流明使用相同导管的常规抽吸可以随后通过从导管中完全去除摄取的物质来补充该过程。

10. 发明授权

US07552853B2 Low-profile vascular closure systems and methods of using same 失效
标题翻译：低调血管闭合系统及其使用方法
公开(公告)号：US07552853B2
公开(公告)日：2009-06-30
申请号：US11626633
申请日：2007-01-24
申请人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Scott J. Epperly , Kenneth A. Eliasen
发明人： Juan-Pablo Mas , Matthew F. Spurchise , Richard D. Lobello , Scott J. Epperly , Kenneth A. Eliasen
IPC分类号： A61B17/068
CPC分类号： A61B17/0057 , A61B17/0218 , A61B17/0644 , A61B17/0684 , A61B17/0686 , A61B17/07292 , A61B17/083 , A61B17/10 , A61B2017/00637 , A61B2017/00668 , A61B2017/22038 , A61B2090/037 , A61B2090/0801 , A61B2090/08021
摘要： A closure device for an arteriotomy includes an elongate tube having a distal opening. The elongate tube has least two opposing longitudinal slots and a pair of opposing corners defined where each slot meets the distal opening. A staple is disposed within the tube, the staple having at least two opposing legs aligned with the at least two slots. Each slot is pinched together adjacent the distal opening such that the opposing corners of each slot converge to cover the tip of the respective staple leg to guard the staple tips against contact with the tissue track. The corners of each slot are separable to permit the respective staple leg to pass there between.
摘要翻译：用于动脉切开术的闭合装置包括具有远端开口的细长管。细长管具有至少两个相对的纵向狭槽和一对相对的拐角，其中每个狭槽都与远端开口相接合。订书针设置在管内，订书针具有与至少两个狭槽对准的至少两个相对的支脚。每个狭槽被夹在邻近远端开口处，使得每个狭槽的相对的角部会聚以覆盖相应的钉腿的尖端，以保护钉末端免受与组织轨迹的接触。每个槽的角部是可分离的，以允许相应的短纤维腿在其间通过。

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