专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5573776A Oral osmotic device with hydrogel driving member 失效
标题翻译：具有水凝胶驱动构件的口腔渗透装置
公开(公告)号：US5573776A
公开(公告)日：1996-11-12
申请号：US303288
申请日：1994-09-08
申请人： Juan M. E. Harrison , Brian L. Barclay , Jerry D. Childers , Jeri D. Wright , Virgil A. Place , Patrick S. Wong
发明人： Juan M. E. Harrison , Brian L. Barclay , Jerry D. Childers , Jeri D. Wright , Virgil A. Place , Patrick S. Wong
IPC分类号： A61K9/00 , A61K31/48 , A61K9/24
CPC分类号： A61K31/48 , A61K9/0004
摘要： An osmotic device (10) for delivering an ergot alkaloid into the mouth of a human patient is disclosed. The device (10) has a size and shape adapting it to be comfortably retained in the mouth for extended periods of time. The device (10) comprises a wall (12) surrounding a compartment (13) housing a layer of an ergot alkaloid (14) and a layer (16) of a fluid swellable, hydrophilic polymer. A passageway (17) in the wall (12) connects the ergot alkaloid (14) with the exterior of the device (10). The wall (12) is permeable to the passage of aqueous biological fluid but substantially impermeable to the passage of the hydrophilic polymer (16). In one embodiment the ergot alkaloid (14) has a different color than the hydrophilic polymer (16). The wall (12) is sufficiently translucent to permit the patient to see the amount of ergot alkaloid (14) remaining to be delivered. Marking lines (19) may be provided on the wall (12) indicating the amount of ergot alkaloid (14) which has been delivered and/or the amount remaining to be delivered.
摘要翻译：公开了一种用于将麦角生物碱输送到人类患者的口中的渗透装置（10）。装置（10）具有适应其舒适地保持在口中长时间的尺寸和形状。装置（10）包括围绕容纳一角麦角生物碱（14）层和流体可溶胀的亲水性聚合物层（16）的隔室（13）的壁（12）。壁（12）中的通道（17）将麦角生物碱（14）与装置（10）的外部连接。所述壁（12）对于水性生物流体的通道是可渗透的，但是对于亲水性聚合物（16）的通过基本上是不透水的。在一个实施方案中，麦角生物碱（14）具有与亲水性聚合物（16）不同的颜色。壁（12）足够半透明以允许患者看到剩余的待转运麦角生物碱（14）的量。标记线（19）可以设置在壁（12）上，指示已经输送的麦角生物碱（14）的量和/或剩余的待传送量。

2. 发明授权

US5512299A Method of treating oral inflammatory disease 失效
标题翻译：治疗口腔炎症的方法
公开(公告)号：US5512299A
公开(公告)日：1996-04-30
申请号：US092024
申请日：1993-07-14
申请人： Virgil A. Place , Myriam T. Encarnacion , Patrick S. L. Wong , Juan M. E. Harrison
发明人： Virgil A. Place , Myriam T. Encarnacion , Patrick S. L. Wong , Juan M. E. Harrison
IPC分类号： A61K9/00 , A61K9/22 , A61K9/20
CPC分类号： A61K31/573 , A61K9/0004 , A61K9/006
摘要： A method of treating inflammatory disease of the mouth by locally delivering beclomethasone dipropionate and related compounds to the oral cavity of a patient over an extended period of time is disclosed. In one embodiment, beclomethasone dipropionate is delivered by an osmotic device (10), in another embodiment, it is delivered by an erosion controlled device (110) and in yet another embodiment, it is delivered by a diffusion controlled device (310).
摘要翻译：公开了一种通过在长时间内将二丙酸倍氯米松和相关化合物局部递送到患者的口腔来治疗口腔炎症的方法。在一个实施方案中，二丙酸倍氯米松通过渗透装置（10）递送，在另一个实施方案中，其由侵蚀受控装置（110）递送，并且在另一个实施方案中，其由扩散控制装置（310）递送。

3. 发明授权

US5512293A Oral sustained release drug delivery device 失效
标题翻译：口服持续释放药物输送装置
公开(公告)号：US5512293A
公开(公告)日：1996-04-30
申请号：US164181
申请日：1993-12-09
申请人： Felix A. Landrau , Patricia S. Campbell , Arthur W. Hall , Juan M. E. Harrison
发明人： Felix A. Landrau , Patricia S. Campbell , Arthur W. Hall , Juan M. E. Harrison
IPC分类号： A61K9/00 , A61K9/20 , A61L15/24 , A61K9/70 , A61K47/32
CPC分类号： A61K9/0004 , A61K9/006 , A61K9/2027
摘要： This invention pertains to a sustained release delivery device for delivering a beneficial agent into the oral cavity of a patient. More particularly, the invention relates to a device comprising about 0.1% to about 20% by weight beneficial agent, about 40% to about 95% by weight ethylene vinyl acetate copolymer having a vinyl acetate content of about 4% to about 80% and about 1% to about 60% by weight polyvinyl pyrrolidone.
摘要翻译：本发明涉及一种用于将有益药物输送到患者的口腔中的持续释放递送装置。更具体地说，本发明涉及包含约0.1％至约20％重量的有益剂，约40％至约95％重量的乙酸乙烯酯含量为约4％至约80％的乙烯 - 乙酸乙烯酯共聚物和约 1％至约60％重量的聚乙烯吡咯烷酮。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式