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1. 发明授权

US06186982B1 Subcutaneous drug delivery device with improved filling system 失效
标题翻译：具有改善灌装系统的皮下给药装置
公开(公告)号：US06186982B1
公开(公告)日：2001-02-13
申请号：US09072875
申请日：1998-05-05
申请人： Joseph Gross , Zvi Nitzan , Izrail Tsals , Mario Razonowich , Oz Cabiri , Haim Danon , Gilad Lavi
发明人： Joseph Gross , Zvi Nitzan , Izrail Tsals , Mario Razonowich , Oz Cabiri , Haim Danon , Gilad Lavi
IPC分类号： A61M3700
CPC分类号： A61M5/14248 , A61M5/14276 , A61M5/14593 , A61M5/155 , A61M2005/14252 , A61M2005/1426 , A61M2005/14264
摘要： A subcutaneous drug delivery device having a housing having an internal reservoir in communication with a drug delivery needle via a fluid path. An expandable chamber disposed adjacent to the reservoir forces drug from the reservoir to the needle when supplied with a gas. A flow regulating chamber, in communication with the fluid path, is capable of volumetric changes in response to temperature and/or pressure changes. An increase in the volume of the flow regulating chamber increases flow resistance to the needle and thereby counteracts the corresponding increase in delivery rate resulting from the expansion of the expandable chamber due to the same volumetric changes in response to temperature and/or pressure. The device also includes an improved filling system that enables the reservoir within the device to be filled with drug from a source without regard to filling position and with a decreased risk of injury from needles. Moreover, the filling system provides an accurate measure of drug transferred into the device thus enabling patients to fill the devices and to ensure proper dosage upon delivery.
摘要翻译：一种具有壳体的皮下药物输送装置，该壳体具有经由流体路径与药物输送针连通的内部储存器。邻近储存器设置的可膨胀室在供应气体时迫使药物从储存器到针头。与流体路径连通的流量调节室能够响应于温度和/或压力变化而发生体积变化。流量调节室的体积的增加增加了对针的流动阻力，从而抵消由于响应于温度和/或压力的相同的体积变化而导致的可膨胀室膨胀导致的输送速率的相应增加。还包括一种改进的填充系统，其使装置内的储存器能够从源处填充药物，而不考虑填充位置并且降低针头受伤的风险。此外，填充系统提供了转移到装置中的药物的精确测量，从而使得患者能够填充装置并确保递送时的适当剂量。

2. 发明授权

US6078842A Electrode and iontophoretic device and method 失效
标题翻译：电极和离子电渗法器件及方法
公开(公告)号：US6078842A
公开(公告)日：2000-06-20
申请号：US997404
申请日：1997-12-23
申请人： Joseph Gross , Zvi Nitzan , Izrail Tsals
发明人： Joseph Gross , Zvi Nitzan , Izrail Tsals
IPC分类号： A61N1/32 , A61N1/04
CPC分类号： A61N1/044 , A61N1/0436 , A61N1/325
摘要： An improved electrode and iontophoretic device and method where the electrode exhibits varied resistance. The electrode is made of a conductive material and applied to a flexible substrate. The variation in resistance can be achieved by varying the thickness of the electrode across its length or by varying the conductivity of the material across the area of the electrode or a combination of both. A pair of such electrodes may be used with a power source in electrical relation thereto and applied over a layer of agent to the skin to deliver the agent into the skin iontophoretically. The pair of electrodes may be shaped so as to cover a portion of the face, hands, feet or other body parts to iontophoretically apply particular agents to those areas.
摘要翻译：改进的电极和离子电渗疗法装置和方法，其中电极具有变化的电阻。电极由导电材料制成并施加到柔性基底上。电阻的变化可以通过改变电极在其长度上的厚度或通过改变电极区域上的材料的导电性或两者的组合来实现。一对这样的电极可以与电源相关联的电源使用并施加到皮肤层上以将试剂输送到皮肤中的离子电渗。一对电极可以被成形为覆盖面部，手部，脚部或其他身体部分的一部分，以将特定的药剂离子电渗应用于那些区域。

3. 外观设计

USD404366S Electronic control unit 失效
公开(公告)号：USD404366S
公开(公告)日：1999-01-19
申请号：US83447
申请日：1998-02-10
申请人： Joseph Gross , Gilad Lavi , Zvi Nitzan
设计人： Joseph Gross , Gilad Lavi , Zvi Nitzan

4. 发明授权

US6157858A Device for the delivery of a substance to a subject and improved electrode assembly 失效
标题翻译：用于将物质输送到受试者和改进的电极组件的装置
公开(公告)号：US6157858A
公开(公告)日：2000-12-05
申请号：US997388
申请日：1997-12-23
申请人： Joseph Gross , Zvi Nitzan
发明人： Joseph Gross , Zvi Nitzan
IPC分类号： A61N1/04 , A61N1/30 , A61N1/32
CPC分类号： A61N1/044 , A61N1/325 , A61N1/0436
摘要： The invention is directed to a device for delivering a pharmaceutically active compound or cosmetic substance to a subject comprises a flexible substrate sheet attached to an electronic controller. The controller is provided with a pair of electrical contacts on the underside thereof and is adhered to the sheet by means of a pair of strips of electrically conductive adhesive. The underside of the sheet is printed in two halves with electrically conductive ink to provide a pair of electrodes separated by an insulating barrier. A protuberance extends from each electrode and is folded onto the top of the sheet such that the contacts of the controller are adhered in electrical connection with the protuberances and thus also with the electrodes. The use of an adhesive to connect a controller in electrical communication with the electrodes enables an extremely simple construction of delivery device to be achieved.
摘要翻译：本发明涉及用于将药学活性化合物或化妆品物质递送到受试者的装置，包括附接到电子控制器的柔性基片。控制器在其下侧设置有一对电触点，并且通过一对导电粘合剂粘合到片材上。片材的下侧用导电油墨印刷成两半，以提供由绝缘屏障隔开的一对电极。突起从每个电极延伸并且被折叠到片材的顶部上，使得控制器的触点与突起电连接并因此粘附在电极上。使用粘合剂来连接与电极电连通的控制器能够实现非常简单的输送装置的构造。

5. 发明申请

US20090204056A1 CONSTANT CURRENT TREATMENT DEVICE 审中-公开
标题翻译：恒定电流处理装置
公开(公告)号：US20090204056A1
公开(公告)日：2009-08-13
申请号：US12300961
申请日：2007-05-17
申请人： Zvi Nitzan
发明人： Zvi Nitzan
IPC分类号： A61N1/30 , A61N1/36
CPC分类号： A61N1/30 , A61N1/0412 , A61N1/0428 , A61N1/325 , A61N1/327
摘要： The present invention provides a device for treatment of a nail condition comprising, at least one active electrode disposed on the nail, at least one counter electrode, at least one power source for providing power to the device, wherein the at least one power source is electrically coupled to the at least one active electrode and the at least one counter electrode; a controllable voltage converter coupled to the at least one power source; and a sensing means coupled to the nail and to the controllable voltage converter, wherein the sensing means is configured to facilitate adjustment of the output voltage of the power source according to the nail resistance to facilitate providing a constant current to the nail with high efficiency. The present invention is also directed to a method of providing a constant current to treat a nail condition.
摘要翻译：本发明提供了一种用于治疗指甲病症的装置，包括：设置在指甲上的至少一个有效电极，至少一个对电极，至少一个用于向装置供电的电源，其中至少一个电源为电耦合到所述至少一个有源电极和所述至少一个对电极; 耦合到所述至少一个电源的可控电压转换器; 以及耦合到钉子和可控电压转换器的感测装置，其中感测装置被配置为便于根据指甲电阻调节电源的输出电压，以便于以高效率向钉子提供恒定的电流。本发明还涉及一种提供恒定电流以治疗指甲状况的方法。

6. 发明申请

US20090045916A1 Battery-assisted backscatter RFID transponder 审中-公开
标题翻译：电池辅助反向散射RFID应答器
公开(公告)号：US20090045916A1
公开(公告)日：2009-02-19
申请号：US11930823
申请日：2007-10-31
申请人： Zvi Nitzan , Doron Lavee , Gaby Guri
发明人： Zvi Nitzan , Doron Lavee , Gaby Guri
IPC分类号： H04Q5/22
CPC分类号： G06K19/0723 , G06K19/0702
摘要： A radio frequency transponder includes at least one battery, which is coupled to provide electrical power for operating the transponder and at least one antenna, which is configured to receive and backscatter RF interrogation radiation from an interrogation device. An integrated circuit is arranged to store a code including information and, powered only with energy provided by the battery, to vary a radiation characteristic of the antenna responsively to the code so as to modulate the information onto the backscattered radiation.
摘要翻译：射频应答器包括至少一个电池，其被耦合以提供用于操作应答器的电力和至少一个天线，其被配置为从询问装置接收和反向散射RF询问辐射。集成电路被布置为存储包括信息的代码，并且仅由电池提供的能量供电，以响应于代码改变天线的辐射特性，以便将信息调制到反向散射辐射上。

7. 发明授权

US08162230B2 Method and circuit for providing RF isolation of a power source from an antenna and an RFID device employing such a circuit 有权
标题翻译：用于从天线和使用这种电路的RFID设备提供电源的RF隔离的方法和电路
公开(公告)号：US08162230B2
公开(公告)日：2012-04-24
申请号：US12424749
申请日：2009-04-16
申请人： Zvi Nitzan , Doron Lavee , Benyamin Almog
发明人： Zvi Nitzan , Doron Lavee , Benyamin Almog
IPC分类号： G06K19/06
CPC分类号： G06K19/07749 , H01Q1/2225 , H01Q1/52
摘要： An RFID device including: electronic circuitry suitable for an RFID device comprising a radio frequency section; an antenna; a battery which provides the device with power; and at least one quarter wavelength transmission line coupled between the battery and one or both of the electronic circuitry and the antenna.
摘要翻译：一种RFID设备，包括：适用于包括射频部分的RFID设备的电子电路; 天线提供设备电源的电池; 以及耦合在电池与电子电路和天线中的一个或两个的至少四分之一波长的传输线。

8. 发明申请

US20100265041A1 RFID TRANSPONDER 审中-公开
公开(公告)号：US20100265041A1
公开(公告)日：2010-10-21
申请号：US12426309
申请日：2009-04-20
申请人： Benyamin ALMOG , Tzahi Hachamo , Zvi Nitzan , Doron Lavee , Paul Fenster
发明人： Benyamin ALMOG , Tzahi Hachamo , Zvi Nitzan , Doron Lavee , Paul Fenster
IPC分类号： H04Q5/22 , H01Q21/00 , H01Q9/16
CPC分类号： G06K19/07749 , H01Q1/2225 , H01Q1/52 , H01Q9/26
摘要： A radio frequency identification (RFID) transponder comprising: an antenna comprising at least two connected dipoles, and having an input port feeding one of the dipoles; a conductive ground plane separated by a predetermined distance from the antenna by a dielectric; and a transponder electrically connected to the input port and operative to produce a response signal when the transponder receives a signal at a given frequency from the antenna.
摘要翻译：一种射频识别（RFID）应答器，包括：天线，包括至少两个连接的偶极子，并具有馈送所述偶极之一的输入端口; 通过电介质与天线隔开预定距离的导电接地平面; 以及应答器，其电连接到输入端口，并且当应答器从天线以给定频率接收到信号时，产生响应信号。

9. 发明授权

US07491465B2 Method of making a thin layer electrochemical cell with self-formed separator 有权
标题翻译：制作具有自形分离器的薄层电化学电池的方法
公开(公告)号：US07491465B2
公开(公告)日：2009-02-17
申请号：US10593742
申请日：2005-03-23
申请人： Zvi Nitzan , Shalom Luski , Ehud Shchori , Dalia Jayes
发明人： Zvi Nitzan , Shalom Luski , Ehud Shchori , Dalia Jayes
IPC分类号： H01M2/14 , H01M10/04
CPC分类号： H01M6/12 , H01M2/1673 , H01M6/40 , H01M10/0436 , Y10T29/49108 , Y10T29/4911 , Y10T29/49115
摘要： A method of forming an electrochemical cell is disclosed. The method comprises contacting a negative pole layer and a positive pole layer one with the other or with an optional layer interposed therebetween. The pole layers and the optional layer therebetween are selected so as to self-form an interfacial separator layer between the pole layers upon such contacting.
摘要翻译：公开了形成电化学电池的方法。该方法包括使负极层和正极层与另一个接触，或者与插入其间的可选层接触。选择它们之间的极层和可选层，以便在这种接触时在极层之间自形成界面分离层。

10. 发明申请

US20070024425A1 Active capacitive coupling RFID device, system and method of production thereof 审中-公开
标题翻译：有源电容耦合RFID器件，系统及其生产方法
公开(公告)号：US20070024425A1
公开(公告)日：2007-02-01
申请号：US11495556
申请日：2006-07-31
申请人： Zvi Nitzan , Doron Lavee , Yoram Karmon
发明人： Zvi Nitzan , Doron Lavee , Yoram Karmon
IPC分类号： H04Q5/22
CPC分类号： G06K19/0723
摘要： The present invention is of an active RFID system configured for SIMPLEX two way communication based on conductive coupling, wherein two way communication is non-simultaneous and can operate on a single frequency comprising at least one capacitive coupling reader, wherein the reader is configured to transmit modulated or unmodulated RF electric signals and to receive and decode data transmitted by the transponder; at least one active capacitive coupling RFID transponder comprising at least one integrated circuit, which is arranged to store a code comprising information and which is configured for capacitive coupled RFID transponder application; at least one antenna configured to receive signal from the at least one reader, and transmit the transponder code comprising information; and at least one power source for providing energy to operate the at least one integrated circuit and transponder transmission; and at least one data processing device for processing the data received from the reader. The fully active transponder includes a carrier frequency control circuit wherein the carrier frequency generator is configured to facilitate correction of frequency error in comparison to the reader transmitter carrier frequency.
摘要翻译：本发明是一种有源RFID系统，其被配置用于基于导电耦合的SIMPLEX双向通信，其中双向通信是非同时的并且可以在包括至少一个电容耦合读取器的单个频率上操作，其中读取器被配置为传输调制或未调制的RF电信号并且接收和解码由应答器发送的数据; 至少一个有源电容耦合RFID应答器，其包括至少一个集成电路，其被布置为存储包括信息的代码，并且被配置用于电容耦合RFID应答器应用; 至少一个天线被配置为从所述至少一个读取器接收信号，并且发送包括信息的所述应答器代码; 以及用于提供能量以操作所述至少一个集成电路和应答器传输的至少一个电源; 以及用于处理从读取器接收的数据的至少一个数据处理装置。完全有效的应答器包括载波频率控制电路，其中载波频率发生器被配置为便于与读取器发射机载波频率相比频率误差的校正。

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