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1. 发明申请

US20070254278A1 Photocurable Perfluoropolyethers for Use as Novel Materials in Microfluidic Devices 有权
标题翻译：可光固化的全氟聚醚用作微流体装置中的新型材料
公开(公告)号：US20070254278A1
公开(公告)日：2007-11-01
申请号：US10572764
申请日：2004-09-23
申请人： Joseph DeSimone , Jason Rolland , Stephen Quake , Derek Schorzman , Jason Yarbrough , Michael Van Dam
发明人： Joseph DeSimone , Jason Rolland , Stephen Quake , Derek Schorzman , Jason Yarbrough , Michael Van Dam
IPC分类号： C07H21/04 , C08J7/04 , F17D1/16
CPC分类号： B01L3/502707 , B01L3/0268 , B01L3/502738 , B01L7/52 , B01L2200/12 , B01L2300/0816 , B01L2400/0481 , B01L2400/0655 , B81B1/006 , B81B2201/058 , B81B2203/0323 , B81C2201/034 , B82Y10/00 , B82Y40/00 , C08G18/5015 , C08G18/8116 , C08G65/007 , C08G65/33348 , C08G2650/48 , C09D163/00 , C09D171/02 , F16K99/0001 , F16K99/0015 , F16K99/0026 , F16K99/0034 , F16K99/0036 , F16K99/0042 , F16K99/0046 , F16K99/0051 , F16K99/0059 , F16K99/0061 , F16K99/0065 , F16K2099/008 , F16K2099/0084 , F16K2099/0086 , G03F7/0002 , Y10T137/0396 , Y10T428/24479 , Y10T428/249954 , Y10T428/3154
摘要： A functionalized photocurable perfluoropolyether is used as a material for fabricating a solvent-resistant microfluidic device. Such solvent resistant microfluidic devices can be used to control the flow of small amounts of a fluid, such as an organic solvent, and to perform microscale chemical reactions that are not amenable to other polymer-based microfluidic devices.
摘要翻译：功能化的光固化全氟聚醚用作制造耐溶剂微流体装置的材料。这种耐溶剂的微流体装置可用于控制少量流体（例如有机溶剂）的流动，并且执行不适合于其它基于聚合物的微流体装置的微量化学反应。

2. 发明申请

US20060083971A1 Liquid materials for use in electrochemical cells 有权
标题翻译：用于电化学电池的液体材料
公开(公告)号：US20060083971A1
公开(公告)日：2006-04-20
申请号：US11040317
申请日：2005-01-21
申请人： Joseph DeSimone , Jennifer Kelly , Jason Rolland , Zhillian Zhou , Ginger Denison , Raymond Dominey
发明人： Joseph DeSimone , Jennifer Kelly , Jason Rolland , Zhillian Zhou , Ginger Denison , Raymond Dominey
IPC分类号： C08J5/20 , H01M4/88 , H01M8/10 , B05D5/12
CPC分类号： C08J5/2256 , C08J5/2262 , C08J2367/00 , H01M4/8828 , H01M8/0221 , H01M8/0234 , H01M8/0258 , H01M8/1004 , H01M8/1025 , H01M8/1027 , H01M8/103 , H01M8/1032 , H01M8/1039 , H01M8/1072 , H01M2300/0082 , Y02P70/56
摘要： Disclosed is the use of liquid precursor materials to prepare a processible polymeric electrolyte, which can be used to form a proton exchange membrane for use in an electrochemical cell. Also disclosed is the use of liquid precursor materials to prepare a processible catalyst ink composition, which can be conformally applied to a proton exchange membrane and a electrode material for use in an electrochemical cell. Also disclosed is the use of a photocurable perfluoropolyether (PFPE) material to form a microfluidic electrochemical cell.
摘要翻译：公开了使用液体前体材料来制备可加工的聚合物电解质，其可用于形成用于电化学电池的质子交换膜。还公开了使用液体前体材料来制备可以适形地施加到质子交换膜和用于电化学电池中的电极材料的可加工催化剂油墨组合物。还公开了使用光固化全氟聚醚（PFPE）材料来形成微流体电化学电池。

3. 发明申请

US20070275193A1 Functional Materials and Novel Methods for the Fabrication of Microfluidic Devices 审中-公开
标题翻译：功能材料和微流控器件制造的新方法
公开(公告)号：US20070275193A1
公开(公告)日：2007-11-29
申请号：US10589222
申请日：2005-02-14
申请人： Joseph DeSimone , Jason Rolland , Ginger Rothrock
发明人： Joseph DeSimone , Jason Rolland , Ginger Rothrock
IPC分类号： B32B7/02 , B05D1/40 , B05D3/02 , C08F16/24 , C12M1/40 , H05H1/00 , G01F13/00 , C08G73/24 , B67D5/00 , B05D3/06
CPC分类号： B81C99/0085 , B01L3/0268 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L2200/12 , B01L2300/0816 , B01L2400/0481 , B01L2400/0655 , B29C66/9121 , B81B2201/051 , B81C1/00206 , B81C2201/019 , B81C2201/034 , F16K99/0001 , F16K99/0015 , F16K99/0034 , F16K2099/008 , F16K2099/0084 , Y10T137/0329 , Y10T428/13 , Y10T428/24
摘要： The presently disclosed subject matter provides functional perfluoropolyether (PFPE) materials for use in fabricating and utilizing microscale devices, such as a microfluidic device. The functional PFPE materials can be used to adhere layers of PFPE materials to one another or to other substrates to form a microscale device. Further, the presently disclosed subject matter provides a method for functionalizing the interior surface of a microfluidic channel and/or a microtiter well. Also the presently disclosed subject matter provides a method for fabricating a microscale structure through the use of a sacrificial layer of a degradable material.
摘要翻译：目前公开的主题提供了用于制造和利用诸如微流体装置的微量装置的功能性全氟聚醚（PFPE）材料。功能性PFPE材料可用于将PFPE材料层彼此粘附或粘附到其它基底上以形成微米级装置。此外，目前公开的主题提供了用于对微流体通道和/或微量滴定阱的内表面进行官能化的方法。此外，目前公开的主题还提供了通过使用可降解材料的牺牲层来制造微结构的方法。

4. 发明申请

US20110215045A1 HIGH FIDELITY THROUGH HOLE FILM, AND ASSOCIATED METHOD 审中-公开
标题翻译：通过孔膜的高密度和相关方法
公开(公告)号：US20110215045A1
公开(公告)日：2011-09-08
申请号：US13000244
申请日：2009-06-19
申请人： Zhilian Zhou , Xiansheng Meng , Joseph M. Desimone , Benjamin Maynor , Jason Rolland , Kenton B. Wiles
发明人： Zhilian Zhou , Xiansheng Meng , Joseph M. Desimone , Benjamin Maynor , Jason Rolland , Kenton B. Wiles
IPC分类号： B01D69/00 , B01D39/00 , B01D71/06 , B29C33/42
CPC分类号： B01D67/002 , B01D39/1692 , B01D2323/12
摘要： A membrane is provided, comprising a first membrane layer having a first side and a second side. The first membrane layer defines a plurality of holes extending along a first axis between the first side and the second side. Each hole is defined by the first membrane layer as a complex three-dimensional shape, and each hole has a diameter of less than about 10 micrometers. The membrane is fabricated by dispersing a liquid polymeric material onto a patterned master template, hardening the polymeric material, and removing it from the master template. The membrane includes through holes which correspond to the structures of the patterned master template in size, cross-sectional and three dimensional shape, orientation, and the like.
摘要翻译：提供了一种膜，其包括具有第一侧和第二侧的第一膜层。第一膜层限定在第一侧和第二侧之间沿着第一轴延伸的多个孔。每个孔由第一膜层限定为复杂的三维形状，并且每个孔的直径小于约10微米。通过将液体聚合物材料分散到图案化的主模板上，硬化聚合物材料并将其从主模板中除去来制造膜。膜包括对应于图案化主模板的尺寸，横截面和三维形状，取向等的结构的通孔。

5. 发明授权

US08518316B2 System and method for producing particles and patterned films 有权
标题翻译：用于生产颗粒和图案化膜的系统和方法
公开(公告)号：US08518316B2
公开(公告)日：2013-08-27
申请号：US13156147
申请日：2011-06-08
申请人： Robert Lyon Henn , Alex Ermoshkin , Kyle Matthew Benjamin Henn , Benjamin Maynor , Jason Rolland , Robert Praino
发明人： Robert Lyon Henn , Alex Ermoshkin , Kyle Matthew Benjamin Henn , Benjamin Maynor , Jason Rolland , Robert Praino
IPC分类号： B28B7/34
CPC分类号： B29C43/222 , B29C33/42 , B29C43/00 , B29C2043/025 , B29C2043/463 , B29L2031/7562 , Y10T428/2982
摘要： A system including a mold having a fluoropolymer wherein the mold defines a plurality of cavities having a predetermined shape and a cross-sectional dimension less than about 100 micrometers; a roller; a surface in cooperation with the roller to form a nip point configured to receive the mold, wherein the nip point is further configured to receive a substantially liquid composition and accelerate entry of the substantially liquid composition into the cavity. A method of forming particles including applying a substantially liquid composition to a mold, wherein the mold comprises a fluoropolymer and defines a plurality of cavities each having a broadest cross-sectional dimension of less than about 100 micrometers; nipping the mold between a roller and a surface such that the substantially liquid composition enters the cavities of the mold; and hardening the substantially liquid composition in the cavities of the mold to form a particle within each cavity, wherein the particle has a size and shape that substantially mimics the size and shape of the cavity of the mold.
摘要翻译：一种包括具有含氟聚合物的模具的系统，其中所述模具限定具有预定形状和横截面尺寸小于约100微米的多个空腔; 滚筒与辊协作以形成被配置为接收模具的夹持点的表面，其中夹持点进一步构造成接收基本上液体的组合物并加速基本上液体的组合物进入空腔。一种形成颗粒的方法，包括将基本上液体的组合物施加到模具，其中所述模具包括含氟聚合物并且限定多个空腔，每个空腔具有小于约100微米的最宽的横截面尺寸; 将模具夹在辊和表面之间，使得基本上液体的组合物进入模具的空腔; 并且在模具的空腔中硬化基本上液体的组合物以在每个空腔内形成颗粒，其中颗粒具有基本上模拟模具空腔的尺寸和形状的尺寸和形状。

6. 发明申请

US20070178133A1 Medical device, materials, and methods 审中-公开
标题翻译：医疗器械，材料和方法
公开(公告)号：US20070178133A1
公开(公告)日：2007-08-02
申请号：US11595533
申请日：2006-11-09
申请人： Jason Rolland
发明人： Jason Rolland
IPC分类号： A61F2/02 , C08F20/00
CPC分类号： A61L27/50 , A61L27/18 , A61L27/34 , C08L83/04 , C08L71/02
摘要： Dual thermal and photo curable materials are used for fabricating, functionalizing, and utilizing devices, such as medical devices, surgical devices, and medical implants. The materials include thermal and photo curable components that can adhere layers of the materials to one another, to other substrates, or to biologic tissues to form medical devices, surgical devices, and medical implants.
摘要翻译：双重热和光固化材料用于制造，功能化和利用诸如医疗装置，手术装置和医疗植入物的装置。这些材料包括可以将材料层彼此粘附到其它基底或生物组织以形成医疗装置，手术装置和医疗植入物的热可光固化组分。

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